XLOC_009707 (enpp2)


Basic Information

Item Value
gene id XLOC_009707
gene name enpp2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 9609721 ~ 9662205 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019446
ACAGTGCCGAGGTTTGAGTAGTCGTTCAGTGTGGAAGAGAGCCACCAGACGCACGTCAACAATGCTGCAACTTAAATGGGTATTCTCCGTTATGTGGCTTTTCTCACGGTTAACAGTGTGTAAGACTTATGTGGTCAGACGGTCCGGAAAGGCTGCATCACCAGACGAATCGCTCTCAAAAAGTTTCTCTGACCAGCCATTTACCAGCCTGGCAGGTTCTTGCAAAAAACGGTGTTTTGAGCTAGTGGAAGCTGATCCACCAAATTGTCGCTGTGACaacctgtgtaaaacatacaataTGTGTTGCTCAGACTTTGATGACCACTGTCTAAAAACTGCAGGGGGTTTTGAATGTAGTAAAGAGCGTTGTGGTGAAAATCGTAATGAGCAGCATGCCTGCCACTGCTCAGAGGACTGCATGGCCAAAGGAGACTGCTGCACCAACTACAGGTCTCTTTGCAAAGGCGATGTTCCTTGGTTGCAAGAAGAGTGTGAAGAGATTAAGAACCACGAGTGTCCTGCTGGGTTTGTTCGACCTCCTGTCATCATGTTGTCTGTTGATGGCTTTCGTGCATCTTACATGAAAAGAGGAGGCACGGTGATCCCCAACATCGAGAAACTCCGATCCTGTGGAACACATGCACCATACATGAGGCCTATGTATCCTACAAAAACCTACCCAAATTTGTATACAATTACAACGgGGCTTTATCCTGAATCGCATGGGATTGTGGGTAACTCCATTCATGATCCAAGCTTTGATGCCAACTTTAACTTCCGTGGGAAAGAGAAGCTTAATCATCGATGGTGGGGAGGCCAGCCTATCTGGATTACTGCAATGAAACAGGGAGTAAAGGCTGGTTCATTTTTCTGGCCAGTTGCCATTCCAATGGAAAGAAGAGTTCTGACCATGTTGCAATGGCTTCATCTCCCCGATGCAGAGagGCCATATCTTTATGCAATGCATTCTGAACAGCTGGATTCATATGGCCACAAACTAGGACCCCACAGCACAGAGCTTAACAGTGCACTAAGGGATGTTGATAAGGTGATTGGACAGCTGATGAATGGCCTGAAACAGATGAAACTACACCGTTGTATCAATATCATTTTGGTTGGAGACCATGGTATGGAGGAAGCTCATTGTGACAAAACAGAGTTCCTAAGTTCTTATATGTCCAACACTGAGGACCTCATCCTAATTCCTGGCTCTCTGGGAAGAATCCGAGCCCGAAATCCCAACAACTCTAAATTTGATGCAAAAGCAGTTGTGGCAAACCTAACATGTAAAAAGCCAGACCAGCACTTTAAGCCATACTTAAAGCAGCATCTTCCCAAACGTTTGCACTATGCCAATAACGACAGAATTGAGGAGATTCATTTAATGGTTGAAAGGAAATGGCACATTGCACGGAAAATCATGAAAACAAAAAGGAATCATGAGAAATGTGGGTTTGCTGGTGATCACGGATATGACAATAAGATCAACAGCATGCAgacaattTTCCTTGGATATGGACCAGCTTTCAAATTCAAAACCAAAATTCCACCATTCGAGAATATTGAGCTTTATAATATCATGTGTGATCTCCTTGGCTTGAAGCCAGCCCCTAACAATGGTACACATGGTAGTCTTAACCAGCTCCTGAGGACCCCTGTATACATACCCAACATGCCTGAAGAAGTGACCAAGCCAAACCCTGCAGGACCAGTCATAGCTATTAATGATGACCTGGGCTGCACTTGTGAAGACAAGAACAAAGTGGACGAGCTCAATCAACGACTGAGACAAGTTATTGATGacaacaagAATCTTCCATATGGGCGTCCAGCTGTTATGTTTCGCACCAAATACTGCATTCTTCATCATACTGACTACATTAGTGGATACAGTGAAGCTTTACATATGCCTCTTTGGACATCTTATACCGTTTCCAAGCAGGTAGACTTTACCCCTCTGACTGATGCTCTGAGCAACTGCATTCGACCTGATAGTAGAGTTCCTACAGCTTACAGCCAGTCCTGCTCAAACTACCGCACAGAAAAACAGATCTCCTACAGTTTCCTCTATCCACCTCAGTTGTCCTCCACTCAGGAAGCAAGATATGATGCTGTTCTCATTACCAACACTGTACCAATGTATGCAGCATTCAAACGAGTGTGGAGTTATTTTCAGAAATCACTTGTGAAACGTTACGCTAGTGAGAAAAATGGTGTGAATGTGGTCACCGGGCCCATTTTCGACTATGACTACAATGGTCTTAGAGATTCTGCAGAGACAATAAAACAGTTTGTCAGTGGCTCCGTACAAATCCCAACTCATTACTTTGTTGTGGTTACAAGCTGCCTCGATTACACACAGACCGTTGACTCCTGTGTTGGTCCTCTCAGTGTGTTCTCCTTCATCCTTCCACACCGATCAGATAATGAAGAGACCTGCAATAGTTCAGAAGATGAGTCAAAGTGGGTGGAGGAACTGATGAAGACTCATACAGCCCGCCTGCGGGATGTGGAGTTACTCACAGGACTGGACTTTTATCGCCGTACCAGCAGGACCTATGAGGAGATTCTCGCTCTGAAAACGTACTTGCACACATACGAAAGTGAGATCTGAAATACTCCCTGCATTAGCATGTCCAAGGTACCTGCAGCCTTCAGTTCCAGACagacacacctgtctgtaattagcAAATGTTCCTGAATGTCTTTATTAGCTAGCTGAGCTGTTTTATCGGGATTGGAGATGAACTTGAGATGAACCTTGAAAATAGGAAAATAATTGGACACCCAATTAAAACTGTGGGATGTGGCAGCGTTTTAtggaaaatataatatttattgttctttCTTAGTTAATCGTTAAGTGTAATATTTTGTCTGTCCTAATGCATTATTCTCCTTTTATATTTGAACTGTACGCATGACCTGACATGTAATAATcacaatatttaaatgtattaacctGTTTGATGCGCTGGAGTCAGATGCCTAAACAAAGTAGACAAgtcttgtttttatattaaatttaagctATTTGACCAAACAGGTAAAGGATAATATCTGTAATCTGCAGTTAAACCTCTTCTGTAGTTTCCTgaataatgttcagttttttaTGC

Function

symbol description
enpp2 Enables lysophospholipase activity and phosphoric diester hydrolase activity. Acts upstream of or within several processes, including Kupffer's vesicle development; animal organ development; and oligodendrocyte differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including axial blood vessel; axis; central nervous system; head; and shield. Orthologous to human ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2).

GO:

id name namespace
GO:0045765 regulation of angiogenesis biological_process
GO:0006935 chemotaxis biological_process
GO:0006955 immune response biological_process
GO:0051216 cartilage development biological_process
GO:0060215 primitive hemopoiesis biological_process
GO:0060217 hemangioblast cell differentiation biological_process
GO:0070121 Kupffer's vesicle development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0060271 cilium assembly biological_process
GO:0034638 phosphatidylcholine catabolic process biological_process
GO:0030334 regulation of cell migration biological_process
GO:0001944 vasculature development biological_process
GO:0048709 oligodendrocyte differentiation biological_process
GO:0050848 regulation of calcium-mediated signaling biological_process
GO:0061371 determination of heart left/right asymmetry biological_process
GO:0005615 extracellular space cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0004528 phosphodiesterase I activity molecular_function
GO:0004551 nucleotide diphosphatase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0030247 polysaccharide binding molecular_function
GO:0004622 lysophospholipase activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0008081 phosphoric diester hydrolase activity molecular_function
GO:0005044 scavenger receptor activity molecular_function

KEGG:

id description
ko00565 Ether lipid metabolism

ZFIN:

id description
ZDB-GENE-040426-1156 Enables lysophospholipase activity and phosphoric diester hydrolase activity. Acts upstream of or within several processes, including Kupffer's vesicle development; animal organ development; and oligodendrocyte differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including axial blood vessel; axis; central nervous system; head; and shield. Orthologous to human ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2).

Ensembl:

ensembl_id ENSDARG00000011257

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019446 True 3119 mRNA 0.43 25 9609721 9662205

Neighbor

gene id symbol gene type direction distance location
XLOC_009706 taf2 coding upstream 3437 9580699 ~ 9606284 (+)
XLOC_009705 ca14 coding upstream 51618 9540033 ~ 9558103 (+)
XLOC_009704 NA coding upstream 81415 9526080 ~ 9528306 (+)
XLOC_009703 NA coding upstream 93914 9515326 ~ 9515807 (+)
XLOC_009702 NA coding upstream 104202 9504373 ~ 9505519 (+)
XLOC_009708 ecm1b coding downstream 51645 9713850 ~ 9725432 (+)
XLOC_009709 pip5k1ab coding downstream 63833 9726038 ~ 9761973 (+)
XLOC_009710 psmd4b coding downstream 100056 9762261 ~ 9777928 (+)
XLOC_009711 zgc:92912 coding downstream 117475 9779680 ~ 9786259 (+)
XLOC_009712 NA coding downstream 350130 10012335 ~ 10016713 (+)
XLOC_009699 CR394537.2 non-coding upstream 372475 9237132 ~ 9237246 (+)
XLOC_009697 NA non-coding upstream 642795 8966209 ~ 8966926 (+)
XLOC_009715 FP016064.1 non-coding downstream 662344 10324549 ~ 10324665 (+)
XLOC_009718 NA non-coding downstream 716126 10378331 ~ 10379821 (+)
XLOC_009719 CU929328.1 non-coding downstream 725514 10387719 ~ 10389787 (+)
XLOC_009724 NA non-coding downstream 955149 10617354 ~ 10617686 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_12087864_12111652 ENPP2 coding CI01000016 null 12087864 ~ 12111772 (+)