XLOC_009714 (tubb5)



Basic Information


Item Value
gene id XLOC_009714
gene name tubb5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 10318893 ~ 10327620 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00019456
GTCCAGGAATATAAAGCCTTTGTCCGGCTTTCTCAAATTATTGCCGAGCCACACCGCTACTTTTTACATTCATTGGAGAACTTCTCGCACAATTTCTAACAATGAGGGAGATTGTTCACATCCAAGCCGGTCAGTGCGGAAACCAAATCGGTGCCAAGTTTTGGGAGGTGATCAGCGATGAACATGGAATCGACCCAACCGGAACCTATCACGGAGACAGTGACCTCCAGCTGGACAGAATTAGTGTCTACTACAATGAGGCTACAGGAGGTAAATATGTGCCAAGAGCCATTCTAGTGGATCTGGAGCCTGGTACCATGGACTCTGTGCGTTCAGGGCCCTTTGGACAGATCTTCAGACCTGACAACTTTGTATTTGGACAGAGCGGTGCTGGTAATAACTGGGCCAAGGGCCACTACACGGAAGGTGCTGAGCTTGTAGATTCAGTTCTGGATGTGGTCCGCAAGGAGTCCGAGAGCTGTGACTGCCTGCAGGGCTTCCAGCTCACTCACTCCCTCGGCGGTGGAACCGGCTCCGGCATGGGTACCCTGCTGATCAGCAAAATCCGCGAAGAGTACCCAGACCGCATCATGAACACATTCAGCGTGGTGCCTTCGCCAAAAGTCTCTGACACCGTAGTGGAGCCTTACAACGCCACGCTGTCGGTTCATCAGCTGGTGGAGAACACAGACGAGACCTACTGCATAGACAATGAAGCCTTATATGATATCTGCTTCCGCACCCTCAAACTCACCACCCCCACATATGGCGACCTCAACCATCTTGTGTCCGCCACCATGAGTGGTGTCACCACCTGCCTGCGCTTCCCCGGCCAGCTCAACGCCGACCTTCGCAAGTTAGCCGTCAACATGGTGCCATTCCCCCGTCTGCACTTCTTCATGCCCGGCTTCGCTCCTCTGACAAGCCGAGGCAGCCAGCAGTACCGCGCCCTCACCGTGCCTGAGCTCACGCAGCAAGTTTTCGACGCCAAGAACATGATGGCGGCCTGCGACCCAAGACATGGGCGCTACCTGACCGTCGCCGCTGTCTTCCGAGGCCGCATGTCTATGAAGGAAGTGGACGAGCAGATGCTGAACGTCCAGAACAAGAACAGCAGCTACTTCGTGGAATGGATCCCCAATAACGTTAAAACCGCCGTCTGCGATATTCCACCTAGGGGTCTCAAAATGGCCGTCACCTTTATTGGTAACAGCACGGCCATCCAAGAGCTGTTCAAGCGTATCTCCGAGCAGTTCACGGCTATGTTCAGGCGTAAGGCTTTCCTGCACTGGTACACGGGCGAGGGGATGGACGAGATGGAGTTCACCGAGGCCGAGAGCAACATGAATGACCTGGTGTCCGAGTACCAGCAGTACCAGGACGCCACCGCCGAGGAAGAGGGCGAATTCGAGGAAGAAGCCGAGGATGATGCTTAAGAAGGAAACTAAAGGGTGTTTTGGGGAGGTGGTAGTGTGTTTAAGTTTTGAGTAAATGTAGCAAAACTTTTATGGAAGTGTCTCAATCAGATGAAGTAGAAATTAGCACTAGACAAAAAGGGGCCAAAAATGAACAGAGGAAGgcagaaagaatgttttttaAACATGGATTAGAGTGGGTAACAGTGTTTACGATTACAGTTCACTCTTTttagtgtgtatgagtgtattaGTTTACCATTCTGATGGTGCGGTACAGAACAGGGAAGCGAAAAGTGGCAAACATCCAGGTAGAATCAGTGTTACAAATTGGGAGGACTGTAACATCTCATTTAAGTTTTATTTGAACGTTTGCTTCTTTTATCTACAAGTAACTTCAGTGAAATTTATCGTGTTTTATTTGTGTGATTTCTTTTGTTACTATTGCACTAGAACAGGGCAGCTCTGTGAAATAATGGCACTTCAATGTGACCTCCAGGGGTCTGATTGCAGTATTGCAAGAAATGTTTGGAAAAGATAAGCATGTCATGGAAATGGTTATGGAAAAGGACTGATGGAATGACAGGGTTATTGAATCTTGGCCTCACTTGGACGCCAACCAACGTCTACAGGAGGACATAAATCAATGGATGGCAAGGGCAATACAGGAAAGGGAAGTATTTTAGATTAGGCAAATAGAAAGACAAGCATGTTGAATGGATTGTTGGTGCAATTTTTTAATTCATGGACTCTGTTATGTCTTATTTCTGAGCCCATCGTTTTAAGTGTTATATTGTTGATTATATATTTCAACAGTTTTGATGTTCCTTGATTGTCCCTGTGTGGAAGGAAACTGAGCCTCTGgagaaaaccaaaataaaaatgaaaacaatttagttaaaaa

Function


symbol description
tubb5 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within fin regeneration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in midbrain hindbrain boundary neural keel; nervous system; optic vesicle; and spinal cord neural tube. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I).

GO:

id name namespace
GO:0007017 microtubule-based process biological_process
GO:0031101 fin regeneration biological_process
GO:0000226 microtubule cytoskeleton organization biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0005856 cytoskeleton cellular_component
GO:0005874 microtubule cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003924 GTPase activity molecular_function
GO:0005525 GTP binding molecular_function
GO:0005198 structural molecule activity molecular_function
GO:0005200 structural constituent of cytoskeleton molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-031110-4 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within fin regeneration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in midbrain hindbrain boundary neural keel; nervous system; optic vesicle; and spinal cord neural tube. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I).

Ensembl:

ensembl_id ENSDARG00000037997

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00019456 True 2319 mRNA 0.48 4 10318893 10327620

Neighbor


gene id symbol gene type direction distance location
XLOC_009713 mrs2 coding upstream 25956 10264286 ~ 10292937 (+)
XLOC_009712 NA coding upstream 302180 10012335 ~ 10016713 (+)
XLOC_009711 zgc:92912 coding upstream 532634 9779680 ~ 9786259 (+)
XLOC_009710 psmd4b coding upstream 540965 9762261 ~ 9777928 (+)
XLOC_009709 pip5k1ab coding upstream 556920 9726038 ~ 9761973 (+)
XLOC_009716 mdc1 coding downstream 2081 10329701 ~ 10345769 (+)
XLOC_009717 si:dkeyp-77h1.4 coding downstream 18657 10346277 ~ 10369298 (+)
XLOC_009718 NA coding downstream 50711 10378331 ~ 10379821 (+)
XLOC_009719 CU929328.1 coding downstream 60099 10387719 ~ 10389787 (+)
XLOC_009720 ino80e coding downstream 85931 10413551 ~ 10422490 (+)
XLOC_009704 NA non-coding upstream 790587 9526080 ~ 9528306 (+)
XLOC_009703 NA non-coding upstream 803086 9515326 ~ 9515807 (+)
XLOC_009702 NA non-coding upstream 813374 9504373 ~ 9505519 (+)
XLOC_009699 CR394537.2 non-coding upstream 1081647 9237132 ~ 9237246 (+)
XLOC_009724 NA non-coding downstream 289734 10617354 ~ 10617686 (+)
XLOC_009733 NA non-coding downstream 1034140 11361760 ~ 11376845 (+)
XLOC_009736 NA non-coding downstream 1245569 11573189 ~ 11578407 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_04193887_04198494 TUBB4B, TUBB4A, TUBB5, TUBB, TBB5, TUBB2B coding CI01000016 null 4193887 ~ 4199380 (+)