XLOC_009731 (gsk3ab)


Basic Information

Item Value
gene id XLOC_009731
gene name gsk3ab
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 11242443 ~ 11292148 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019482
CAGAATCCTAACGAGACTTCAgctatctttatttttttaacgattattgttgtttaaattgaCATATCTACCACGCGCCTGGGCCAGTCTACCGGCACACTTTACCCCCGCTCTGGCACATTTGCAACCCGAAATGAGCGGCAGCGGGCGGCCCAGGACTAGCTCGTTTGCTGAGCCTCCGGGGGTTCCGGGAGCCGCTGCAGCCGCCGCCGGATCAGCCGTCGCCGGTGGAAGCTCATCAGGAAAGACGGGGGGCGCGCAGGCCTCAGGCGGGAGTTCGTCTGGTTTCGGAAACCTAAAGCTGGGCAGGGACAGTGGGAAAGTGACGACAGTAGTAGCCACACCAGGGCAGGGTCCCGACCGTCCTCAGGAGGTTTCGTACACGGACATCAAGGTGATCGGGAATGGCTCATTCGGAGTGGTTTATCAGGCTCGGCTCATCGACAGCCAGGAGATGGTGGCCATAAAGAAGGTGCTTCAGGATAAGAGGTTTAAGAACCGTGAGCTACAGATAATGAGGAAGTTGGACCACTGTAATATTGTCAGGCTACGCTACTTCTTCTACTCCAGTGGAGAAAAGAAAGATGAAGTGTATCTAAATTTGGTGCTTGATTTTGTACCAGAAACCGTGTACAGGGTGGCACGCCACTTCAACAAGTCCAAAACCACCATCCCCATTATCTATGTCAAAgTGTATATGTATCAGTTATTTCGCAGTCTGGCGTATATTCATTCCCAAGGCGTCTGCCATAGAGACATCAAGCCACAGAATCTCCTGGTGGACCCAGACACAGCTGTACTCAAACTGTGTGACTTTGGCAGTGCAAAGCAGTTAGTTCGTGGAGAGCCAAATGTGTCATACATCTGTTCCCGGTATTACCGTGCTCCTGAGCTAATATTCGGAGCCACGGATTACACATCCAACATTGATATCTGGTCAGCCGGCTGTGTATTAGCGGAGCTGCTTCTGGGACAGCCCATATTCCCCGGTGACAGTGGAGTGGACCAGTTAGTGGAGATCATCAAGGTTTTGGGGACCCCCACAAGAGAACAGATCCGAGAGATGAACCCCAACTACACAGAGTTTAAATTCCCACAGATCAAAGCACACCCTTGGACAAAGGTGTTTAAGCCGAGGACTCCTCCAGAAGCCATCTCGTTGTGTTCTCGTCTGCTGGAGTACACGCCGGTGACGCGGCTCTCTCCGCTGGAGGCCTGCGCACACGCCTTCTTTGATGAGCTGCGCCAGCCCAATGCCCGTCTGCCTAATGGCCGAGAACTTCCCCAGCTCTTCAACTTCAGCCCTGTGGAGCTGTCTATCCAACCACAGTTGAACTCCATTCTCATTCCTCCACATGCTCGCTCGCAGACGACACCTGCCTCGCACGAGGGCAGCGGTTCAGACGGTCCAGCCCAGTCCAGCTCCGCACCAGGACCCCTGAGCAACAACACCTAATTGTTCCCTTGGCATTACTGCGACGTTATCACCCCTCTCTCCACCATCCCTTCTTTCTCATTCCTCTCTCCTTCCCAACAGCAGCTCCAAACAGTCTCTCTTGCACAAATCTCtttctcacacacgcacactcccGTCACCTCGTGTTACGTGTACTCACATTCTCCAATAATGGAAGAAGTGTGTGTGATGCCCAGAATAACGACGTCACCGGAGGTCGATTTAAATTCGGTATGATTGAGCTGGTAAGGTTTTAACCCTGGGAGGGGTACGTTTTTGGGCACCTCTGCCCTCTAGTGGCAGGAAGAGCACCGCACAGTTACTGCTCTCTGCCAGCCATCAATTTTTAAAGCTATCGAGCTCATTTAAATTAGATTTCGCTCTTAAAAACGATACCTTTTAGCCAAGTTCTTAAACAAAAGCAAGGTCTGTGATGTGTTTTATGAAGCAGCGAGTGTGAGATGtccgtgtttgtgtgttttctcttCTCGCCGAGACGAAAATGAGTGTCTTAATATGCGTGTATGTAAGTTTTAAGTAATCATTGCACACTCTTTTGGGTTTTAATGTCTTTTAAGGAGAATATTTAGGTGTTTGGATACGCTGAGGTAGAATGGGTGTAGAAACgtgctcatgcacacacacgcattaTAACGCATAGGTCAATCCCATTAATAGCTGTGTCTGTTTGATTACAGTTGTGCATTATGAAGTCGACACCggtgtgtgagtgtttgtataCATTGGTGTGGCCATTAAATGTGGATTTAGCGGATGCTcgttcaaaacaaacaaacaaaacacaccatGAACACAGCAAATGAGACTCGAAAACGGAGCTGTTAGTCTTTCCCTTCCTCcatccttcctctctctctctcattgctAATATGTAAATGCCATGTaccttttattttgttatttttgttattgttattctgTTGTCCTTGTAATTAGATTTTCCTCCTAGTGGAGCAGTGCTGGCGTGAGCAGAAACCAGCCTTtctcggtctctctctctctctctctctttgtctctcgctctcttcttttcttcttctccTTTCCCTCCATCATACGACTGTATATAACATTTCATCCAGCCTCTCCCAGAATCTGGGGAGGAAGACGAAACTGaacaaaattttgtttttacctgATATCTTtcagtctctctctttctttctctctctctcgctctctctctctcctcgctCGCCCACCGGCCTGTCCTTCCCCTTCCTCATCAGTGTTAATTCtgatctttttatttattgtattgctGTCTGTTAACAGTCTGATGGGGGAggggttttgtgtgtgtgatgtcatTTGGTGTAACATTCATATCTCAAACTCCGATAGAATGTTCTGGAAAGGGCAGGTCCACACTATATATACCACACACAGGCTGCTCGGCCCATCGGtcaagagatgaacggttcacgggagagagagggagacatgaactatgtttttgtttgttggtataaataataaactcattaataaaGT
>TCONS_00019483
ACATTTGCAACCCGAAATGAGCGGCAGCGGGCGGCCCAGGACTAGCTCGTTTGCTGAGCCTCCGGGGGTTCCGGGAGCCGCTGCAGCCGCCGCCGGATCAGCCGTCGCCGCTGCGCCAGCCCAATGCCCGTCTGCCTAATGGCCGAGAACTTCCCCAGCTCTTCAACTTCAGCCCTGTGGAGCTGTCTATCCAACCACAGTTGAACTCCATTCTCATTCCTCCACATGCTCGCTCGCAGACGACACCTGCCTCGCACGAGGGCAGCGGTTCAGACGGTCCAGCCCAGTCCAGCTCCGCACCAGGACCCCTGAGCAACAACACCTAATTGTTCCCTTGGCATTACTGCGACGTTATCACCCCTCTCTCCACCATCCCTTCTTTCTCATTCCTCTCTCCTTCCCAACAGCAGCTCCAAACAGTCTCTCTTGCACAAATCTCtttctcacacacgcacactcccGTCACCTCGTGTTACGTGTACTCACATTCTCCAATAATGGAAGAAGTGTGTGTGATGCCCAGAATAACGACGTCACCGGAGGTCGATTTAAATTCGGTATGATTGAGCTGGTAAG
>TCONS_00019484
CAAATGTGTCATACATCTGTTCCCGGTATTACCGTGCTCCTGAGCTAATATTCGGAGCCACGGATTACACATCCAACATTGATATCTGGTCAGCCGGCTGTGTATTAGCGGAGCTGCTTCTGGGACAGCCCATATTCCCCGGTGACAGTGGAGTGGACCAGTTAGTGGAGATCATCAAGGTTTTGGGGACCCCCACAAGAGAACAGATCCGAGAGATGAACCCCAACTACACAGAGTTTAAATTCCCACAGATCAAAGCACACCCTTGGACAAAGGTGTTTAAGCCGAGGACTCCTCCAGAAGCCATCTCGTTGTGTTCTCGTCTGCTGGAGTACACGCCGGTGACGCGGCTCTCTCCGCTGGAGGCCTGCGCACACGCCTTCTTTGATGAGCTGCGCCAGCCCAATGCCCGTCTGCCTAATGGCCGAGAACTTCCCCAGCTCTTCAACTTCAGCCCTGTGGAGCTGTCTATCCAACCACAGTTGAACTCCATTCTCATTCCTCCACATGCTCGCTCGCAGACGACACCTGCCTCGCACGGTACTGATCACACTTACAAACACAGTGCCTTTGATTTACCCTTCATGTCAGTCTGTGTGGATTTGTGAATGCACGTGCCCTGAAGTATACTtcggtttttatttttatgctacaGTATACTGTACGATGCTGCAGATAGACAATGATAAAGTGTGTCAGTGTTGGTCAGAGATATTGGCAGTAGCTGATTTCTTTGACGATTTCaaggttttttaaaaaaacagataGAAAACACCCTTGCCATTTTTGCTTGAACAGATTGGAATTAGACTTCATTGGAAACTGTAAAGAGTTTACGTTCATTTGTGTGCCTGCAATAAACCCATCATGCATttgtaaataaagaaaacatacaGGATAA

Function

symbol description
gsk3ab Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within cardiac muscle cell development; dorsal/ventral pattern formation; and heart looping. Predicted to be active in axon; cytosol; and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).

GO:

id name namespace
GO:0055013 cardiac muscle cell development biological_process
GO:0010975 regulation of neuron projection development biological_process
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0016310 phosphorylation biological_process
GO:0001947 heart looping biological_process
GO:0032007 negative regulation of TOR signaling biological_process
GO:0007165 signal transduction biological_process
GO:0030424 axon cellular_component
GO:0005829 cytosol cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990714-3 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within cardiac muscle cell development; dorsal/ventral pattern formation; and heart looping. Predicted to be active in axon; cytosol; and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).

Ensembl:

ensembl_id ENSDARG00000015681

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019482 False 2971 mRNA 0.48 10 11242443 11292148
TCONS_00019483 False 576 nonsense_mediated_decay 0.57 4 11242560 11290883
TCONS_00019484 True 901 lncRNA 0.47 4 11275659 11283602

Neighbor

gene id symbol gene type direction distance location
XLOC_009730 cicb coding upstream 17999 11151699 ~ 11224444 (+)
XLOC_009729 erfl3 coding upstream 99646 11029762 ~ 11142797 (+)
XLOC_009728 pou2f2a coding upstream 251203 10918252 ~ 10991240 (+)
XLOC_009727 dedd1 coding upstream 379402 10841163 ~ 10863041 (+)
XLOC_009726 atp1a3b coding upstream 421534 10776688 ~ 10820909 (+)
XLOC_009732 znf574 coding downstream 5555 11297703 ~ 11344727 (+)
XLOC_009733 NA coding downstream 69612 11361760 ~ 11376845 (+)
XLOC_009734 grik5 coding downstream 191663 11483811 ~ 11555934 (+)
XLOC_009735 zgc:198329 coding downstream 266720 11558868 ~ 11569729 (+)
XLOC_009736 NA coding downstream 281041 11573189 ~ 11578407 (+)
XLOC_009724 NA non-coding upstream 624757 10617354 ~ 10617686 (+)
XLOC_009719 CU929328.1 non-coding upstream 852656 10387719 ~ 10389787 (+)
XLOC_009718 NA non-coding upstream 862622 10378331 ~ 10379821 (+)
XLOC_009715 FP016064.1 non-coding upstream 917778 10324549 ~ 10324665 (+)
XLOC_009712 NA non-coding upstream 1225730 10012335 ~ 10016713 (+)
XLOC_009737 NA non-coding downstream 288504 11580652 ~ 11583878 (+)
XLOC_009751 NA non-coding downstream 825483 12117631 ~ 12139336 (+)
XLOC_009755 CR388102.1 non-coding downstream 1008021 12300169 ~ 12300286 (+)

Expression


Co-expression Network