XLOC_009750 (gnb3a)



Basic Information


Item Value
gene id XLOC_009750
gene name gnb3a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 12022543 ~ 12049762 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00019508
TCTGCCCATCACAAAAGCATCACAGAGAGAGAGGGACGGGGATCAGGAGGTGCGTACGGCAGAAAATCTGAATGAACATTGTCCTGAGAAAACAGCAAGTGTGGATACAGAGTCGCAAAGGGATAAGAAATACAAACAGAGTGGAGGAACACCCAAAAGTAACAAGAGAGTTTTTCCCAGCATTCTCTCTGCTTTACTGACCTCACTTCCTGTCTCTGGGTGACTGTGCCTGAAAACCGTTGCCATGGGTGAAATGGAGCAACTGCGAAAGGAGGCGGAGAAGCTGAAGGATGACATCACTGCAGCTCGTAAAACCGTGCAGGACCTTACACTGCAGGATCATGTGGCCGGGACGGCTGTGGTGGGACGTGTCCAGCTAAAGACCAGAAAGACATTGAGAGGACATCTGGCCAAAATCTATGCCATGCATTGGGGGACAGACTCAAAACTGTGCGTCAGTGCTTCTCAGGACGGTAAACTGATTGTATGGGACAGCTACACCACCAATAAGGTGCATGCAATCCCACTGAAGTCCTCATGGGTGATGACATGTTCATACGCACCTTCAGGGAACATGGTGGCCTGTGGAGGACTTGACAACATGTGCTCCATTTACAACCTGAAGGCCAAAGATGGAAACGTGAAGGTCATGCGTGAGCTCGCAGCACATACAGGTTACCTGTCCTGCTGCCGTTTTCTGAGTGACAGTGAGATCATCACCAGCTCTGGAGACTGTACCTGTGTTCTGTGGGACATCGAGACAGGATCACAGAAGACGGTGTTTGCAGGTCATCTGGGAGACTGTATGTCCCTCGCCGTGTCTCCAGACTTTAACACCTTCATCTCAGGGGCTTGTGACTTCACTGCCAAACTGTGGGACATCCGTGAAGGCCAGTGCAGACAGACCTTCGGTGGACACGAGAGTGACATCAACGCCATTGGGTTTTTCCCCAACGGCAATGCAGTGATCACAGGTTCAGACGATGCTTCCTGCAAGTTGTACGACCTGCGCTCAGACCAGGAGCTCATCACATACCAGGACTCCAGCATCATGTGCGGCGTGACATCCATCGCTCCGTCCCTCTCCGGAAGACTCATCCTCGCCGGATACGATGACTTCAACTGCAACATCTGGGATTCACTTAAGTCAGAGAGAGTCGgaGTGCTGTCTGGTCATGACAACAGAGTGAGCTGCATCGGTGTGACTCCTGACGGGATGGCCTGCTGCACAGGATCATGGGACAGCTTCCTGAAGATCTGGAACTAACGCTCTGTCTCGAAGATGGGCAAAAATCACAACATGTCAAAGACAGGGTAAAAATGTAAAGGGGACAACTGAAACAGGACTATGAGAAATAGTGGTAAAAGCAGGGAGGGAAAGCGATATGGTTGCTGTGGCGTCACAACGAGAACGATTATGAATAAGAAAACCTCATTTAGAGACGGGCTGATCTGTAGAATAATCTTGTCAAAGAAATCACGCAATAACAGAAATCTTGTCTTTCAGGGATTGCTAACTGCAAACGTGGGCATTTATAAAGCCATTACCTATTTTTGGTGATTTTGTGAGgtaattttgttttcattcacaCATGGGTGTGTTAACAGCATATTAACAATGTAGCATATGAAACAAGACTTTCAACACTAGTTGAATAAAGCTTACTGATATCTAAATGCATCCTGTGCTATCAAAACCGAACGACGGAGGTTGCCAAAATAGTTACGCAAGATCGAGTATACAATGACTTCAGGCTACACTGAATGATATTTTCACTTTTATAAAATGTGGTTTACAACCTCTAGATAGATTCGACAAGTTTTAGTGAGAGTGTCTGAGGAAGCTTCGTTTGTTAAGTTTAGTGTTAGATTTTGATTTTTGGGATAGTGCACTGATAGtgtcatgtattttttttcttctgcttattCGGGCCAATAAAACAAGTACTATGGAAAAA

Function


symbol description
gnb3a Predicted to enable signaling receptor complex adaptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in nervous system. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005834 heterotrimeric G-protein complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0031682 G-protein gamma-subunit binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-134 Predicted to enable signaling receptor complex adaptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in nervous system. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3).

Ensembl:

ensembl_id ENSDARG00000004358

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00019508 True 1958 mRNA 0.46 9 12022543 12049762

Neighbor


gene id symbol gene type direction distance location
XLOC_009749 p3h3 coding upstream 15715 11992498 ~ 12006828 (+)
XLOC_009748 cxcr3.3 coding upstream 182409 11834516 ~ 11840134 (+)
XLOC_009747 cxcr3.2 coding upstream 197240 11818126 ~ 11825303 (+)
XLOC_009746 si:dkey-250k15.4 coding upstream 237257 11779534 ~ 11785286 (+)
XLOC_009745 ceacam1 coding upstream 261947 11724230 ~ 11760596 (+)
XLOC_009751 NA coding downstream 67869 12117631 ~ 12139336 (+)
XLOC_009752 tpi1b coding downstream 186577 12236339 ~ 12254994 (+)
XLOC_009753 zgc:92606 coding downstream 215396 12265158 ~ 12276225 (+)
XLOC_009754 si:dkey-26c10.5 coding downstream 231270 12281032 ~ 12294468 (+)
XLOC_009755 CR388102.1 coding downstream 250407 12300169 ~ 12300286 (+)
XLOC_009737 NA non-coding upstream 438665 11580652 ~ 11583878 (+)
XLOC_009736 NA non-coding upstream 444136 11573189 ~ 11578407 (+)
XLOC_009733 NA non-coding upstream 645698 11361760 ~ 11376845 (+)
XLOC_009724 NA non-coding upstream 1404857 10617354 ~ 10617686 (+)
XLOC_009719 CU929328.1 non-coding upstream 1632756 10387719 ~ 10389787 (+)
XLOC_009756 CR388102.6 non-coding downstream 330968 12380730 ~ 12380846 (+)
XLOC_009764 NA non-coding downstream 913198 12962960 ~ 12963877 (+)
XLOC_009765 NA non-coding downstream 1062502 13112264 ~ 13115609 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000016_05117302_05122058 GNB3A, GNB3 coding CI01000016 null 5115426 ~ 5122712 (+)
bowfin (Amia calva) AMCG00004663 NA coding CM030121.1 CM030121.1 56093109 ~ 56096391 (-)