XLOC_009899 (apoc1)


Basic Information

Item Value
gene id XLOC_009899
gene name apoc1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 23972126 ~ 23973721 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019755
GAAAATCTCCGTGAAAACAGCTGTTGTGGCAAACGGAGTTTACTTACCTCTAAAGGATGTTTACTATAGTCATTTACCACATCGCAAAGCTGTAAGGAGAACGAGAGATGAACGCGAGGAAAGCGAGTGATTGCAGGAGGTCTTGATAGGTCAGAGGTGGTGTTATTACACAACGTCATCTCTGTGTCCCTATAAAGGGACAAGCCATCTGTGGGACATCACAAACTCAGCCCAATTCTTTCGAGGACTGCGAAGAGGGAAAAAAACGACAAGATGAAATTGTACTTGGCTGCAGCCGTGCTGATGCTTGTACTTGCTGTACACACAGAGGCCCAGGAGGAGCCCACACTGGAGCAGCATTTCACAAAATTTGGGACCCAGATGAAGGAGATTGCAGAGGACCTGGCAGATAAGACCAAAACCGCCTTCCAGAACATTGAACAGAGCGAGCTTGGTACCAAAACCAGGAACTGGTTTAACGATCAATATGAGAAGCTGAAGCAAAAGATGACTGAAaccttcaattaaaaaaaatgaaaaatcaagcCCCATTTACCTTACACCCCCAATTACCTTGTGTTTTGTGATATCACCTCAAAACTGTTGAGCCGACTGGCACATTTGTTACAGACCAATACAAAGTCACACTGTGATGATCTGCTTGTCATTTGTGTAATGTGTAAAATAGTTAATTTTGTGGGATGctgtaaaataagaaaaaatgagATAAAAAATACATGCAGATTTTCCTTTTCAAAAGAATAAACAGTGGAAAAA
>TCONS_00019756
GAAAATCTCCGTGAAAACAGCTGTTGTGGCAAACGGAGTTTACTTACCTCTAAAGGATGTTTACTATAGTCATTTACCACATCGCAAAGCTGTAAGGAGAACGAGAGATGAACGCGAGGAAAGCGAGTGATTGCAGGAGGTCTTGATAGGTCAGAGGTGGTGTTATTACACAACGTCATCTCTGTGTCCCTATAAAGGGACAAGCCATCTGTGGGACATCACAAACTCAGCCCAATTCTTTCGAGGACTGCGAAGAGGGAAAAAAACGACAAGATGAAATTGTACTTGGCTGCAGCCGTGCTGATGCTTGTACTTGCTGTACACACAGCAGAGGCCCAGGAGGAGCCCACACTGGAGCAGCATTTCACAAAATTTGGGACCCAGATGAAGGAGATTGCAGAGGACCTGGCAGATAAGACCAAAACCGCCTTCCAGAACATTGAACAGAGCGAGCTTGGTACCAAAACCAGGAACTGGTTTAACGATCAATATGAGAAGCTGAAGCAAAAGATGACTGAAaccttcaattaaaaaaaatgaaaaatcaagcCCCATTTACCTTACACCCCCAATTACCTTGTGTTTTGTGATATCACCTCAAAACTGTTGAGCCGACTGGCACATTTGTTACAGACCAATACAAAGTCACACTGTGATGATCTGCTTGTCATTTGTGTAATGTGTAAAATAGTTAATTTTGTGGGATGctgtaaaataagaaaaaatgagATAAAAAATACATGCAGATTTTCCTTTTCAAAAGAATAAACAGTGGAAAAATAA

Function

symbol description
apoc1 Predicted to enable fatty acid binding activity and phospholipase inhibitor activity. Acts upstream of or within cell migration involved in gastrulation. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Is expressed in DEL; blastoderm; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and obesity. Orthologous to human APOC1 (apolipoprotein C1).

GO:

id name namespace
GO:0042074 cell migration involved in gastrulation biological_process
GO:0034447 very-low-density lipoprotein particle clearance biological_process
GO:0006641 triglyceride metabolic process biological_process
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance biological_process
GO:0042157 lipoprotein metabolic process biological_process
GO:0032375 negative regulation of cholesterol transport biological_process
GO:0050995 negative regulation of lipid catabolic process biological_process
GO:0051005 negative regulation of lipoprotein lipase activity biological_process
GO:0005576 extracellular region cellular_component
GO:0034361 very-low-density lipoprotein particle cellular_component
GO:0034364 high-density lipoprotein particle cellular_component
GO:0005504 fatty acid binding molecular_function
GO:0004859 phospholipase inhibitor activity molecular_function

KEGG:

id description
ko04979 Cholesterol metabolism

ZFIN:

id description
ZDB-GENE-030131-1074 Predicted to enable fatty acid binding activity and phospholipase inhibitor activity. Acts upstream of or within cell migration involved in gastrulation. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Is expressed in DEL; blastoderm; and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease and obesity. Orthologous to human APOC1 (apolipoprotein C1).

Ensembl:

ensembl_id ENSDARG00000092170

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019755 False 777 mRNA 0.42 4 23972126 23973718
TCONS_00019756 True 783 mRNA 0.42 4 23972126 23973721

Neighbor

gene id symbol gene type direction distance location
XLOC_009898 apoeb coding upstream 8665 23960744 ~ 23963461 (+)
XLOC_009897 apoa4b.2 coding upstream 23588 23947196 ~ 23948538 (+)
XLOC_009896 si:dkey-7f3.14 coding upstream 47281 23923746 ~ 23924845 (+)
XLOC_009895 apoa4b.2 coding upstream 49258 23921610 ~ 23922868 (+)
XLOC_009894 apoa4b.1 coding upstream 55863 23913943 ~ 23916263 (+)
XLOC_009900 apoa2 coding downstream 5257 23978978 ~ 23980354 (+)
XLOC_009901 apoc2 coding downstream 10458 23984179 ~ 23994642 (+)
XLOC_009902 NA coding downstream 45387 24019108 ~ 24028618 (+)
XLOC_009903 NA coding downstream 224758 24198479 ~ 24207903 (+)
XLOC_009904 CT867948.1 coding downstream 542371 24516092 ~ 24524076 (+)
XLOC_009889 CR533578.1 non-coding upstream 364774 23607231 ~ 23607352 (+)
XLOC_009875 NA non-coding upstream 1275630 22695226 ~ 22696496 (+)
XLOC_009872 NA non-coding upstream 1392800 22575143 ~ 22579326 (+)
XLOC_009870 NA non-coding upstream 1643098 22327970 ~ 22329028 (+)
XLOC_009869 NA non-coding upstream 1644624 22323766 ~ 22327502 (+)
XLOC_009905 NA non-coding downstream 592013 24565734 ~ 24573801 (+)
XLOC_009910 NA non-coding downstream 861054 24834775 ~ 24897111 (+)

Expression


Co-expression Network