XLOC_009928 (tyrobp)


Basic Information

Item Value
gene id XLOC_009928
gene name tyrobp
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 25196572 ~ 25200757 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019798
CTTCTTGTATTCGAGTCAGGGCTGTGTAAACCCTGAGCAATCTTTCCTAAACCTGTCTGCACTCATTATGAGAAGGATACTGTTTATAATGTTCCCCGTCAACGGACTGTTTGGCTTTGTAGAGGCAAATCAAGACTGCAGTTCCTGTTACCAGATGGACATTGGAGTGGCTGTGGGGATCATCACGTGTGATATTATTGTCACGCTCCTCATTGCTCTCTCCGTCTACTGTTTTGTTTCTCGCCAGAAAAAGAGAGGGAGTTTACATGCACACGGCAGATGCTGTAGCTCAGGCAAAGCAAAGCTTCAGCAGACATCTATGAGGGCAAAACCAATTGAAGTAGAATCACCTTACCAGGAGCTTTATGGAGTGCAGTCAGACATATACAGTGATCTTCAGCAGTATCGGAAATAAACAAGGTCACCTAACATTATCAATGAACGAGTTGTGTTCACACCAATATTTGGAGATTGCATAGGTTCATGACGGTTTCATATTGTGGCATACAAATATGTATTTGATATAAATAAGCTATAATAATTGAATCATGCAAAACAATTTCCATGAATCATCATGATTGGTACATataaaaatcatcaaaataaatgttaatggtTTGTGGAAAGGAAATGATCTTCAGGAACTTGAAGATTTAATTCCACATTTTATTATagttgtaaaagtttttttttttttttgtatctttatATGTcagttttgtatttattcataGTATATCTTTGTATTGGAAGATTCCCTTGCTCCTTAtggtaaaataaatgtgtttgatTTTAA

Function

symbol description
tyrobp Predicted to enable signaling receptor binding activity. Acts upstream of or within phosphatidylinositol 3-kinase signaling. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in cell surface. Is expressed in liver; lymphocyte; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP).

GO:

id name namespace
GO:0002282 microglial cell activation involved in immune response biological_process
GO:0002283 neutrophil activation involved in immune response biological_process
GO:0032911 negative regulation of transforming growth factor beta1 production biological_process
GO:0034241 positive regulation of macrophage fusion biological_process
GO:0014065 phosphatidylinositol 3-kinase signaling biological_process
GO:0030889 negative regulation of B cell proliferation biological_process
GO:0016310 phosphorylation biological_process
GO:1904151 positive regulation of microglial cell mediated cytotoxicity biological_process
GO:0032816 positive regulation of natural killer cell activation biological_process
GO:0009986 cell surface cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0016301 kinase activity molecular_function

KEGG:

id description
ko04650 Natural killer cell mediated cytotoxicity
ko04380 Osteoclast differentiation

ZFIN:

id description
ZDB-GENE-061130-2 Predicted to enable signaling receptor binding activity. Acts upstream of or within phosphatidylinositol 3-kinase signaling. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in cell surface. Is expressed in liver; lymphocyte; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP).

Ensembl:

ensembl_id ENSDARG00000094894

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019798 True 796 mRNA 0.36 5 25196572 25200757

Neighbor

gene id symbol gene type direction distance location
XLOC_009927 hcst coding upstream 8763 25184207 ~ 25187809 (+)
XLOC_009926 wu:fe05a04 coding upstream 15030 25171832 ~ 25181542 (+)
XLOC_009925 znf576.2 coding upstream 26727 25163443 ~ 25169845 (+)
XLOC_009924 znf576.1 coding upstream 33359 25137483 ~ 25163213 (+)
XLOC_009923 CU062628.1 coding upstream 61360 25133335 ~ 25135212 (+)
XLOC_009929 NA coding downstream 6861 25207618 ~ 25213978 (+)
XLOC_009930 NA coding downstream 18678 25219435 ~ 25242310 (+)
XLOC_009931 NA coding downstream 33196 25233953 ~ 25235093 (+)
XLOC_009932 klhl38b coding downstream 45100 25245857 ~ 25250414 (+)
XLOC_009933 fbxo32 coding downstream 58556 25259313 ~ 25272633 (+)
XLOC_009913 BX539313.2 non-coding upstream 277615 24905556 ~ 24918957 (+)
XLOC_009912 dre-mir-125a-1 non-coding upstream 298319 24898171 ~ 24898253 (+)
XLOC_009910 NA non-coding upstream 299461 24834775 ~ 24897111 (+)
XLOC_009911 dre-let-7d-1 non-coding upstream 315354 24881122 ~ 24881218 (+)
XLOC_009905 NA non-coding upstream 622771 24565734 ~ 24573801 (+)
XLOC_009937 dre-mir-30d non-coding downstream 140659 25341416 ~ 25341543 (+)
XLOC_009938 dre-mir-30b non-coding downstream 140967 25341724 ~ 25341811 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G140921 NA unknown CI01000027 null 5757776 ~ 5757799 (+)