XLOC_009988 (itga8)


Basic Information

Item Value
gene id XLOC_009988
gene name itga8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 28383758 ~ 28512860 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019883
AGTACGCAGGGTTCGCGCAGAGAAAGGCGCGCAGCTTGCAAGAGGGCAGCAGCAGACGCGTGGAGCGCGCACTCAACATATGACAGCTCAACACGGACATACCGTACACTCTCTCTGCACATCTTTAAGCAGCATATATGGATTACACTCGGACACACAGGGCTGAAGCCATGCACTCTTGTTTGTCCCGCATGCGTTTTCGATGCTTTTTCCTCATGTTGTCATTTTTTTGCGAAGCTGCAGCTTTTAACCTGGATTTAGAAAAGCCCACGGTTTACAATGGACCTGAGGGAAGTTATTTTGGATACTCACTGGACTTTTACCACCCAACACAGGATAGAAACGTCATGTCGGTGTTGGTTGGGGCTCCTAAAGCGAACACCTCTCAGCCGGGGATTGTGGAGGGAGGAGCGGTGTACTACTGCCCCTGGCCGGCATCAGACCCAGACTCCTGCCGCCAGATCCCCTTTGATAAAGCAAATAACCGTATGATTAAAGTGAACGGGACACGAGAGCCTCTAGAATTTAAATCCCATCAGTGGTTTGGAGCAACAGTCAGGACCCACAAAGGCAAAGTGGTGGCCTGTGCTCCCCTCTATCAATGGAGGACAGTGAAGGTCAGCAGTGAGATGGATCCTGTGGGAACCTGTTATGTGGCTGTGCAGAACTTTAGTGCCTATGCTGAGTATTCACCCTGTAGAACCAATAACCCAGACCCAGAGGGCCAGGGCTTCTGCCAGGCGGGCTTCAGTGTTGATTTTACTAAGgaAGGGACTCTGGTCGTGGGAGGACCAGGGAGTTTCTACTGGCAAGGCCAAGTGATAACAGCCGGAGTTGCCGAGATATTAAACGGCTATTCTCTGAAAACAATCCTGCGTAAAGTTCAAGGAGAAAAGCAGACGGTGGCAGCATCAGACACGTACGATGACAGTTACCTTGGATATTCTGTAGCGGTTGGAGAGTTCACAGGGGATTCGGAACAAGAATTGGTAGCAGGGGTTCCTCGAGGGGCACACAACTTTGGTTATgtGACAGTGATCAATGCAACAAACCTGACGTTCATTCAGAACTTTACTGGAGAGCAGATGGCCTCTTACTTTGGATACACCATTGCAGTGACTGATCTAAATGGAGATGGGTTAGACGACGTGCTAGTTGGAGCTCCACTCTATATGGACCGCGAGTTTGAGAGTAAGCCTCGAGAGGTGGGCCGGGTTTATTTATATCTGCAAGAAGATGTGCTTCTCTTCTCTCCTCCCATCACACTCACTGGAATGCACCTGTTTGGCCGCTATGGAAGTGCCATTGCTCCTCTTGGAGATATCAACCAGGATGGCTATCTTGACGTGGCTATAGGGGCTCCATTCGCCGGGGAGGATCGTGGTGGCAGAGTCTTTATCTATAATGGGCAGAAATCCGGCCTGATGTTACAGGCTTCTCAAGTGCTGAAAGGCGACTGGGCCTCATCTGGCATCCCAGCAGGCTTTGGATTCACCCTTCGTGGAGATTCTGACCTCGACAACAACCAGTACCCTGATTTGCTGGTCGGTGCATTTGGAGTGAGTAAAGTCGTGGCCTACAGGTCAAGACCAGTGGTGACCGTGGATGCTCAGCTGATTTTAAGACCCAGAATCCTTAACCCAGAGGACAAGTCTTGCCGAATGCCCAATTCTGATATCATGGTAACCTGCCTGTCAGTAAATGTGTGTGCAAAGATCTCTGGGATTGGTATTCCTGATTATGTAGCTCTGCGGATGGAGCTACAGCTGGACTGGCTGAAGCAGCGTGGAGCAGTAAAGCGGGTCTTGTTCATGGACTCTCACCAACACCAGCGGAGCCAGCAGCTGGTTCTGGGTCAAGGGGACCGCCAGCACTGCCACAACTACTCTGTGTACCTGCGGGATGAGGCCGAGTTCAGGGATAAACTGAGTCCTATCAGCGTGACACTGAACTACAGTCTGGACCAAAGCTCTCCTCCTGCTGGCCTACAGCTGCGGCCTGTGTTGGATCACTACAGCAAGACCTTCCACCACGAGCAGGCAAACATCCTGTTGGACTGTGGAGAAGACAACATGTGCATCCCAGATCTCAAACTCTCTGCTAAAATGGACCGGACTGAGCTTATAATCGGGGATGACAACTTGCTGATGTTGACTATTAATGCAGCCAATGAGGGTGAGGGGGCGTATGAGGCGGAGCTTCACGTGACCCTCCCACCAGAGGCAGATTATATAGGTGTGGAGCGTAGGCGTGAGgATCTTCAGCGGCTGAACTGTGAACACAGGACGGAGAATGACACCAGGATTGTGGTGTGTGATCTGGGGAACCCAATGGTTGCTGATACAAATTTGTCGGTGGGTTTACGGTTTTCCGTGGCGAGGCTGGAGGACGCCCCTCCTACCATTGGCTTTGAGGTGCAGATCCACAgCTCTAACAAGGACAACTCAAGAAGTGTCCCAGTGAATTTGACTCTAAGCATTGTGGCAAGAGCAGAGGTGGAGATAAGAGGTGTGTCTCATCCCGCTCAGGTTGTTTTGCCTTTCCCTCGATGGGAGCCCAAAGAGAAACCTGTGAGAGAGGATGAAGTCGGTCCTCAGGTTCAGCACATATATGAGTTACATAACAAAGGTCCGAGTTCAATAAGCAGGACAGTGCTGGAGGTGGGCTGGCCCAGTCGCTACCGTGAAGAGCACCTTCTCTATGCACTTCAGGTCATTACTGACGGACCGGTTCACTGCAGCACCAACAGCTCCCTCAACCCACTGGAGTTGGAGACCTCGACTCTTCAGGACACTCCAGAGTTACTGGGCTTCCTGAGGAACAGCAGCGGAGTGACCCGCCGAAGACGATCTGTTTCTATAGGCCAAAGCTACAACAGCAAAACACTGaACTGCTCGAATATCAACTGTCTGATGGTGGAGTGTGTAGTGGACCGTCTGGATCGAGGGCAAAGTGCAGTGATCAAGTTCAGATCTCGACTCTGGGCTTACACCTTCTTACAGAGAAGGAATGACCACTACACGCTAAACTCCACAGTGTCCTTTCAAGTGACGGCCATGCCTTATCGCATCAAAGCTGAGACACTCCCACGCCAGAGCAAATCAATCGGCACGTTTGTGGTGTGGGCCATTCCTGACGTCTCCTTTGCCATTCCCCTGTGGGTCATAATTCTGGCTATACTGCTGGGACTGCTGGTGCTGGCAGTGCTTAGCCTAGCAATGTGGAAGTGTGGCTTCTTCGATCGTGCGCGGCCACCCAAAGATGATGACGTGTCAGACCGCGAGCAGCTGACCGCAGAAAAATCCACAGACGCGTGAGAGCAGACCAGATGACCAAAAATGAACGAAGAGGCCATGGATTGAATCTCCATGAAGACAGTGGAGGAGCTGCGTCCAAGAGTTCAGTATCTGCTGAAGAACACAGATCAAAGCCTCTAAATAAACTACAGCTCCCACACTGGACTGCCATCTGTGAGCTGGGCCACAGTTCcactcaaaaacatttatttaaattgacgGATAAGAGCAAGAACTCTGAGCATTGCACACTGATAGAGCTGTAATATACACAAGATCCAATGAGCCACTTGACTAGAGGCTGATCAGTACAGTCCAAAAACATCAAGATCTCATTGTCCAATCAACTCCATTGACTTCTTTTTTTATGGTTGTGATGAGGATTTCCGAGGACATACTGTTTAACTGTATCAGTGGAACTCAAGAATATTTGATCTCAATCACCAGCTCAAAACAGGATCTGGATCATTCCGCAATTCACCTTActttggctgcatttacactgcatctAAATATGGAGTCACTCctcttttaagacctttttttgttttattatttaaatatcgaAATCAAACTGTTGGCATCCATGTTTGATGTTTACAGCAGAGAGAGAATTTAAAACTCGCTTcgaattagaattttttttgtaCACACAAAACGATAATTTAAATGTTCACACCAACATTCACACTCTGCTGTGTGTATATGAGCATTTTAACAGAATGTTTCAAGAAAACATTCAACAAAGTCACATATAATGTCACATACTATATGCAAATTGTTAATGTCACCTGCAGTACAGTTCATATAGTCATAAAAGGAGCTGAATGTTACAGATAAGAACGCAGCTTGTTGATAATGATGGAGGGATGCATTTTGTGTGTTGCAGCTGACTAGAGTCTAGATTCTTAGACCCTGTTTACATCTGCTATTAGATGTGTTTTTGTAGATCCAACCACAAATGGACAATGCCAAATACAGGTGTAAACCAGGGCTGAAACTTTTTGGGCTTGTTCACTTTTGATTACTTTCATAGGTAGccaaaaacacattcattcaaaTGGCAAACCAGCCAGGGTTTGAACTTTGTCATCTGAAATTGTACGTTTGGTTTGAAGATCAAAAAATTTGAAGTAAAAATCATAGTTAGAATACTAGCAGTTaaaggaacactttttttttttgaaatacaTTTTGCAGTGATTAAAAAGAATCCCAGCTAGGTAAGTAGGTAACAGCGCTGTGTAA
>TCONS_00019884
CTTGCAAGAGGGCAGCAGCAGACGCGTGGAGCGCGCACTCAACATATGACAGCTCAACACGGACATACCGTACACTCTCTCTGCACATCTTTAAGCAGCATATATGGATTACACTCGGACACACAGGGCTGAAGCCATGCACTCTTGTTTGTCCCGCATGCGTTTTCGATGCTTTTTCCTCATGTTGTCATTTTTTTGCGAAGCTGCAGCTTTTAACCTGGATTTAGAAAAGCCCACGGTTTACAATGGACCTGAGGGAAGTTATTTTGGATACTCACTGGACTTTTACCACCCAACACAGGATAGAAACGTCATGTCGGTGTTGGTTGGGGCTCCTAAAGCGAACACCTCTCAGCCGGGGATTGTGGAGGGAGGAGCGGTGTACTACTGCCCCTGGCCGGCATCAGACCCAGACTCCTGCCGCCAGATCCCCTTTGATAAAGCAAATAACCGTATGATTAAAGTGAACGGGACACGAGAGCCTCTAGAATTTAAATCCCATCAGTGGTTTGGAGCAACAGTCAGGACCCACAAAGGCAAAGTGGTGGCCTGTGCTCCCCTCTATCAATGGAGGACAGTGAAGGTCAGCAGTGAGATGGATCCTGTGGGAACCTGTTATGTGGCTGTGCAGAACTTTAGTGCCTATGCTGAGTATTCACCCTGTAGAACCAATAACCCAGACCCAGAGGGCCAGGGCTTCTGCCAGGCGGGCTTCAGTGTTGATTTTACTAAGgaAGGGACTCTGGTCGTGGGAGGACCAGGGAGTTTCTACTGGCAAGGCCAAGTGATAACAGCCGGAGTTGCCGAGATATTAAACGGCTATTCTCTGAAAACAATCCTGCGTAAAGTTCAAGGAGAAAAGCAGACGGTGGCAGCATCAGACACGTACGATGACAGTTACCTTGGATATTCTGTAGCGGTTGGAGAGTTCACAGGGGATTCGGAACAAGAATTGGTAGCAGGGGTTCCTCGAGGGGCACACAACTTTGGTTATgtGACAGTGATCAATGCAACAAACCTGACGTTCATTCAGAACTTTACTGGAGAGCAGATGGCCTCTTACTTTGGATACACCATTGCAGTGACTGATCTAAATGGAGATGGGTTAGACGACGTGCTAGTTGGAGCTCCACTCTATATGGACCGCGAGTTTGAGAGTAAGCCTCGAGAGGTGGGCCGGGTTTATTTATATCTGCAAGAAGATGTGCTTCTCTTCTCTCCTCCCATCACACTCACTGGAATGCACCTGTTTGGCCGCTATGGAAGTGCCATTGCTCCTCTTGGAGATATCAACCAGGATGGCTATCTTGACGTGGCTATAGGGGCTCCATTCGCCGGGGAGGATCGTGGTGGCAGAGTCTTTATCTATAATGGGCAGAAATCCGGCCTGATGTTACAGGCTTCTCAAGTGCTGAAAGGCGACTGGGCCTCATCTGGCATCCCAGCAGGCTTTGGATTCACCCTTCGTGGAGATTCTGACCTCGACAACAACCAGTACCCTGATTTGCTGGTCGGTGCATTTGGAGTGAGTAAAGTCGTGGCCTACAGGTCAAGACCAGTGGTGACCGTGGATGCTCAGCTGATTTTAAGACCCAGAATCCTTAACCCAGAGGACAAGTCTTGCCGAATGCCCAATTCTGATATCATGGTAACCTG

Function

symbol description
itga8 Acts upstream of or within cilium assembly and embryonic viscerocranium morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Is expressed in hair cell; head; inner ear; neuromast hair cell; and pharyngeal arch. Human ortholog(s) of this gene implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (integrin subunit alpha 8).

GO:

id name namespace
GO:0007229 integrin-mediated signaling pathway biological_process
GO:0060271 cilium assembly biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0007155 cell adhesion biological_process
GO:0008305 integrin complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG:

id description
ko04151 PI3K-Akt signaling pathway
ko04512 ECM-receptor interaction
ko04514 Cell adhesion molecules
ko04510 Focal adhesion
ko04810 Regulation of actin cytoskeleton
ko05165 Human papillomavirus infection
ko05410 Hypertrophic cardiomyopathy
ko05412 Arrhythmogenic right ventricular cardiomyopathy
ko05414 Dilated cardiomyopathy
ko04515 Cell adhesion molecules

ZFIN:

id description
ZDB-GENE-080220-48 Acts upstream of or within cilium assembly and embryonic viscerocranium morphogenesis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Is expressed in hair cell; head; inner ear; neuromast hair cell; and pharyngeal arch. Human ortholog(s) of this gene implicated in end stage renal disease; ovarian cancer; renal agenesis; and schizophrenia. Orthologous to human ITGA8 (integrin subunit alpha 8).

Ensembl:

ensembl_id ENSDARG00000078717

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019883 False 4544 mRNA 0.48 30 28383758 28512860
TCONS_00019884 True 1656 mRNA 0.50 15 28383792 28451338

Neighbor

gene id symbol gene type direction distance location
XLOC_009987 NA coding upstream 12428 28270015 ~ 28371330 (+)
XLOC_009986 NA coding upstream 333730 28049554 ~ 28050028 (+)
XLOC_009985 znf804b coding upstream 384902 27957808 ~ 27998856 (+)
XLOC_009984 NA coding upstream 510391 27839927 ~ 27873367 (+)
XLOC_009983 glipr2l coding upstream 761575 27614989 ~ 27622183 (+)
XLOC_009990 fam171a1 coding downstream 34297 28547157 ~ 28574789 (+)
XLOC_009991 nmt2 coding downstream 65492 28578352 ~ 28591541 (+)
XLOC_009992 acbd7 coding downstream 83695 28596555 ~ 28599328 (+)
XLOC_009993 crot coding downstream 89114 28601974 ~ 28627568 (+)
XLOC_009994 NA coding downstream 147535 28660395 ~ 28667333 (+)
XLOC_009977 CR848817.1 non-coding upstream 967946 27415697 ~ 27415812 (+)
XLOC_009973 LO017763.1 non-coding upstream 1176961 27206669 ~ 27206797 (+)
XLOC_010005 NA non-coding downstream 698502 29211362 ~ 29230847 (+)
XLOC_010006 NA non-coding downstream 733020 29245880 ~ 29250848 (+)
XLOC_010014 NA non-coding downstream 1078259 29591119 ~ 29600668 (+)
XLOC_010018 NA non-coding downstream 1208767 29721627 ~ 29813252 (+)

Expression


Co-expression Network