XLOC_001017 (ern2)


Basic Information

Item Value
gene id XLOC_001017
gene name ern2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 9169807 ~ 9195760 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001615
TGAAGAACTGGACACAGATGCTGCTGTTGCTGGTTTGCTTCGCTGGAATCGTGTCTCAGTGTGAGGGAGGAAGCTCCGTCTCTCTGCCCGAGTCTCTGCTCTTTGTTTCTACACTGGATGGAAGTCTGCATGCCGTCAGCAAACAGACCGGAGACATCAAATGGACACTGAAGGAAGATCCCATTATACAGGTTCCCGAGTATTTCCAAGAGCCAGGCTTTTTACCAGACCCCAATGACGGAAGTCTGTATGTTCTCGGAGGAAAGAGGAAAGAAGGTCTGATGAAACTGCCATTCACTATTCAAGAGCTGGTGCAGTCGTCTCCCTGCAGGAGCTCAGATGGAGTACTCTACACCGGTAAAAAACAGGACACCTGGTTTGTGGTCGATCCTCAGACAGGTGAAAAACAGACAAGTTTGAGCACCTCGTCTTCAGACTCCATCTGTCCCTCTGCACCTCTGTTGTACATCGGTCGCACAgAATATATGATCACCATGTATGACACGAAGACTCAGGAGCTCCGCTGGAATGCCACATACAACGATTACTCAGCTCCTCTATATGACgacaaaaaatatgaatataAGATGTCGCACTTTGCATCGAGTGGCGATGGTCTGGTGGTTACGGTGGATCGAGACTCTGGCGAGGTTTTGTGGATGCAGAAATTTGATTCTCCGGTGGCTGGATTTTACTTGTGGAGTCAGGACAGTCTCCGTCGAGCCCCTCATCTGACCGTCGCAACAGAAACCCTGCGCTATCTGACCTTCACCGCAGAAAACACACAGTCCCACACCATGAAGTGGACCTACCAGTTCACAAAGGAGAGCCACAGCACGAAGACTCAGCTAGTTCCCACTCTGTATGTTGGGAAGACGGAGTCTCATCTGTATGCTTCTGCCTCCCTTGTCCATCAAGGTGTCGCAATAGTGCCTAAGGGTCTCACTCTTGCACGCATTGAGGGGCCGATGACAGCAGGCGTCACAATGGGTAATGGACGGCCTGAGTGCGAGATCACACCCAGCACTGACGTCAAATATCCACCAGGAAGCAGCAGCTCTCTGCAGAATCAGTGGCTGCTCATTGGTCACCATGAAATCCCTCCTCTGGCTCACACCACCATGTTGAGAGATTTCCCAGAGAACCTGCAGCGCTCTGGTGATGTCATCCCACCTCGAGGATCCGGCTCTTCTTACCGCTCTCCCTCTCACCCATTGCCACCAGTTAGGAAGCAGAGCTCttctccagtgctgccagactcGCTGAGCTCTGAGCCCATGACAGTGCTGGTGGTGACGCTGCTGCTAGGAGCCTGGATCACCTTCCTGCTCACACACAAATGGCCTGTAAAAAAATCCCAAAGATCTGAAGAGCCAGTGGACTCCACCCCACTTTCTGGTCTGACCAATTACAGCGCTTCTACAGAACTGAACACTCCGCCCTCAACATCATCTTACAGCAACAGCAGTCGCTCAGAAAAGACCAGTTCTGTTGCATCCAATCAAACTCAGCCATTCTCAAGCAAAGACTCCGCCTCTGTAACAGCAGCCAGCCAATCACAGAATGAACAGGCTGACGTGGTGGAAGTTGGTAAAATCTCTTTCAGTCCCACTGAGGTGTTGGGTCATGGGACAGAAGGAACCTTCGTGTTTCGGGGTCATTTTGACGGTCGGCGTGTGGCGGTGAAGCGAATCCTGCCggagtgtgtggagtttgcagagCGAGAGGTTCAACTTCTGCGGGAATCAGATGAACATCCCAATGTGATCCGTTACTTCTGCACAGAGCGGGACAGACAGTTCACTTACATTGCCATAGAGCTGTGTGCTGCAACACTCCagcagTATGTAGAAGACCCGAGCTGTCCTCACTCAGAGCTGAACCCGGTGTCCCTGCTGGAGCAGACCATGTGTGGCCTCAGTCACCTGCACTCCCTCAACATCGTCCACAGGGATTTAAAGCCCAGGAATATTTTGCTGTCTCTGCCCGGGGCACTGGGTCGAGTGCGGGCGCTCATCTCAGATTTCGGCTTGTGTAAGAAGCTTCCAGATGGTCGGCACAGTTTCAGCCTACGCTCCGGGATACCTGGAACCGAAGGCTGGATCGCCCCTGAATTACTCATAAACGCTCCGAAAGGGAACCCTACGAGTGCGGTGGACATTTTTTCTGCCGGATGTGTGTTTTATTATGTGACGTCTAAAGGACAGCATCCGTTCGGTGACACTCTGCGGCGTCAGGCTAACATCCTCTCTGGAGTCTATAACCTCGATCACTTCATGGAGGATATACATGAGGACGTGATTGGCAGAGATCTGATCGAGCGGATGATCAGTGCAGAGCCAGAGAGCCGTCCTTCAGCAGCGTCAATTCTTAAACACCCCTTCTTCTGGAGTCCAGAGAAACAGCTGCAGTtctttcagGACGTCAGTGACAGGATTGAGAAGGAGCCTACAGAAAGTCCTATAGTGGCTCGTCTGGAAAATTCTGGCAGATCTGTCGTAAGAACCAACTGGAGGATGCACATCTCAGCGCCGCTGCAGGCTGATCTTAGAAAATTTCGTACATATAAAGGAAACTCAGTGAGAGACCTGCTTAGAGCAATGAGGAATAAAAAACACCATTATCACGAGCTCCCGCCGGAGGTTCAGTCGACTCTCGGTGAAGTCCCCGATGGCTTTGTGGCGTATTTCACCTCACGGTTCCCCCGGTTACTGCTTCACACGCACACAGCACTCAGCATCTGTGCCCCCGAGAGACCCTTTCACCCGTACTATCATCACTGA
>TCONS_00001616
CTCGGTGAGAATGGCGTTTTGTTGGAGGAGTTTGGAGTGTTTTCCTGGTTTTCTCTTCAGTGTGAGGGAGGAAGCTCCGTCTCTCTGCCCGAGTCTCTGCTCTTTGTTTCTACACTGGATGGAAGTCTGCATGCCGTCAGCAAACAGACCGGAGACATCAAATGGACACTGAAGGAAGGTACTTATGTATATGTGCAATATGACAAGCCAGGCTTTTTACCAGACCCCAATGACGGAAGTCTGTATGTTCTCGGAGGAAAGAGGAAAGAAGGTCTGATGAAACTGCCATTCACTATTCAAGAGCTGGTGCAGTCGTCTCCCTGCAGGAGCTCAGATGGAGTACTCTACACCGGTAAAAAACAGGACACCTGGTTTGTGGTCGATCCTCAGACAGGTGAAAAACAGACAAGTTTGAGCACCTCGTCTTCAGACTCCATCTGTCCCTCTGCACCTCTGTTGTACATCGGTCGCACAgAATATATGATCACCATGTATGACACGAAGACTCAGGAGCTCCGCTGGAATGCCACATACAACGATTACTCAGCTCCTCTATATGACgacaaaaaatatgaatataAGATGTCGCACTTTGCATCGAGTGGCGATGGTCTGGTGGTTACGGTGGATCGAGACTCTGGCGAGGTTTTGTGGATGCAGAAATTTGATTCTCCGGTGGCTGGATTTTACTTGTGGAGTCAGGACAGTCTCCGTCGAGCCCCTCATCTGACCGTCGCAACAGAAACCCTGCGCTATCTGACCTTCACCGCAGAAAACACACAGTCCCACACCATGAAGTGGACCTACCAGTTCACAAAGGAGAGCCACAGCACGAAGACTCAGCTAGTTCCCACTCTGTATGTTGGGAAGACGGAGTCTCATCTGTATGCTTCTGCCTCCCTTGTCCATCAAGGTGTCGCAATAGTGCCTAAGGGTCTCACTCTTGCACGCATTGAGGGGCCGATGACAGCAGGCGTCACAATGGGTAATGGACGGCCTGAGTGCGAGATCACACCCAGCACTGACGTCAAATATCCACCAGGAAGCAGCAGCTCTCTGCAGAATCAGTGGCTGCTCATTGGTCACCATGAAATCCCTCCTCTGGCTCACACCACCATGTTGAGAGATTTCCCAGAGAACCTGCAGCGCTCTGGTGATGTCATCCCACCTCGAGGATCCGGCTCTTCTTACCGCTCTCCCTCTCACCCAGTAAGTCCAAAGCCAATAAAACTCATCTGTGCAATTAGGAAGCAGAGCTCttctccagtgctgccagactcGCTGAGCTCTGAGCCCATGACAGTGCTGGTGGTGACGCTGCTGCTAGGAGCCTGGATCACCTTCCTGCTCACACACAAATGGGTCAGAAATACATTTACTGAtttttttttaaattgtgatgTATATTCTTCAGATGAACAGGCTGACGTGGTGGAAGTTGGTAAAATCTCTTTCAGTCCCACTGAGGTGTTGGGTCATGGGACAGAAGGAACCTTCGTGTTTCGGGGTCATTTTGACGGTCGGCGTGTGGCGGTGAAGCGAATCCTGCCggagtgtgtggagtttgcagagCGAGAGGTTCAACTTCTGCGGGAATCAGATGAACATCCCAATGTGATCCGTTACTTCTGCACAGAGCGGGACAGACAGTTCACTTACATTGCCATAGAGCTGTGTGCTGCAACACTCCagcagTATGTAGAAGACCCGAGCTGTCCTCACTCAGAGCTGAACCCGGTGTCCCTGCTGGAGCAGACCATGTGTGGCCTCAGTCACCTGCACTCCCTCAACATCGTCCACAGGGATTTAAAGCCCAGGAATATTTTGCTGTCTCTGCCCGGGGCACTGGGTCGAGTGCGGGCGCTCATCTCAGATTTCGGCTTGTGTAAGAAGCTTCCAGATGGTCGGCACAGTTTCAGCCTACGCTCCGGGATACCTGGAACCGAAGGCTGGATCGCCCCTGAATTACTCATAAACGCTCCGAAAGGGAACCCTACGAGTGCGGTGGACATTTTTTCTGCCGGATGTGTGTTTTATTATGTGACGTCTAAAGGACAGCATCCGTTCGGTGACACTCTGCGGCGTCAGGCTAACATCCTCTCTGGAGTCTATAACCTCGATCACTTCATGGAGGATATACATGGTGTAGATCTGATCGAGCGGATGATCAGTGCAGAGCCAGAGAGCCGTCCTTCAGCAGCGTCAATTCTTAAACACCCCTTCTTCTGGAGTCCAGAGAAACAGCTGCAGTtctttcagGACGTCAGTGACAGGATTGAGAAGGAGCCTACAGAAAGTCCTATAGTGGCTCGTCTGGAAAATTCTGGCAGATCTGTCGTAAGAACCAACTGGAGGATGCACATCTCAGCGCCGCTGCAGGCTGATCTTAGAAAATTTCGTACATATAAAGGAAACTCAGTGAGAGACCTGCTTAGAGCAATGAGGAATAAAAAACACCATTATCACGAGCTCCCGCCGGAGGTTCAGTCGACTCTCGGTGAAGTCCCCGATGGCTTTGTGGCGTATTTCACCTCACGGTTCCCCCGGTTACTGCTTCACACGCACACAGCACTCAGCATCTGTGCCCCCGAGAGACCCTTTCACCCGTACTATCATCACTGA

Function

symbol description
ern2 Predicted to enable endoribonuclease activity; protein serine/threonine kinase activity; and unfolded protein binding activity. Predicted to be involved in IRE1-mediated unfolded protein response and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to act upstream of or within mRNA processing and protein phosphorylation. Predicted to be located in membrane. Predicted to be part of IRE1-TRAF2-ASK1 complex. Is expressed in liver. Orthologous to human ERN2 (endoplasmic reticulum to nucleus signaling 2).

GO:

id name namespace
GO:0030968 endoplasmic reticulum unfolded protein response biological_process
GO:0006397 mRNA processing biological_process
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress biological_process
GO:0006468 protein phosphorylation biological_process
GO:0036498 IRE1-mediated unfolded protein response biological_process
GO:1990604 IRE1-TRAF2-ASK1 complex cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0004521 endoribonuclease activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004540 ribonuclease activity molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0051082 unfolded protein binding molecular_function

KEGG:

id description
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-090312-15 Predicted to enable endoribonuclease activity; protein serine/threonine kinase activity; and unfolded protein binding activity. Predicted to be involved in IRE1-mediated unfolded protein response and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to act upstream of or within mRNA processing and protein phosphorylation. Predicted to be located in membrane. Predicted to be part of IRE1-TRAF2-ASK1 complex. Is expressed in liver. Orthologous to human ERN2 (endoplasmic reticulum to nucleus signaling 2).

Ensembl:

ensembl_id ENSDARG00000058475

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001615 False 2783 mRNA 0.52 22 9169807 9195629
TCONS_00001616 True 2622 mRNA 0.51 20 9169807 9195760

Neighbor

gene id symbol gene type direction distance location
XLOC_001016 BX004779.2 coding downstream 7170 9157310 ~ 9162637 (-)
XLOC_001015 NA coding downstream 30647 9138638 ~ 9139160 (-)
XLOC_001014 palb2 coding downstream 35762 9132335 ~ 9134045 (-)
XLOC_001013 palb2 coding downstream 39671 9125023 ~ 9130136 (-)
XLOC_001012 ndufab1a coding downstream 46342 9118100 ~ 9123465 (-)
XLOC_001018 BX004779.1 coding upstream 2099 9197859 ~ 9197966 (-)
XLOC_001019 gng13a coding upstream 31321 9227081 ~ 9228007 (-)
XLOC_001020 si:dkeyp-57d7.4 coding upstream 34484 9230244 ~ 9231952 (-)
XLOC_001021 zgc:136472 coding upstream 39168 9234928 ~ 9249943 (-)
XLOC_001022 ubn1 coding upstream 63171 9258931 ~ 9278037 (-)
XLOC_001010 NA non-coding downstream 87035 9081842 ~ 9082772 (-)
XLOC_001009 NA non-coding downstream 189136 8978905 ~ 8980671 (-)
XLOC_001008 NA non-coding downstream 191844 8974500 ~ 8977963 (-)
XLOC_001023 AL954703.1 non-coding upstream 112511 9308271 ~ 9321931 (-)
XLOC_001024 NA non-coding upstream 225064 9420824 ~ 9422275 (-)
XLOC_001031 NA non-coding upstream 720616 9916376 ~ 9918812 (-)
XLOC_001037 CR854964.1 non-coding upstream 1074487 10270247 ~ 10272725 (-)

Expression


Co-expression Network