XLOC_010207 (sqlea)


Basic Information

Item Value
gene id XLOC_010207
gene name sqlea
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 43401005 ~ 43413293 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020210
agcataaattaTTCAGCATCACCTAGAAGCATCTCACCAGCTCGAGTGCGCCCATGTGCTGGGGATTAaacttactttttatttattattatttattataaaaggaATTTAACTGAAGTCGAGCCCGAGATTAATCGGAAAACGGAtactatatgttttttttccactttttgtGTCTGTCTGGAATAATTCAGTTAATTTTCAGATCACCTGTGCTGCTCTTTTGTGATATTTTTAAACGCCATTAAGCGATATTTTGTGTCTGTTTATAATTGAAGCGAGTGTCGACATGTGGACCTTTCTTGGCATAGCGAGTTTTACATATATCTATAAGAAATGCGACGCGCTGCTGAGCTCCGCGACTACAGAGCTGCTGGTGGCCGCGGTGCTGTGCGTGTCTGTGGGGCTCATCATCACCTGTTTCTCCCTCCGCGGACAGACTCTCAAAGCGCCGCAGTTTTTACAAATGCCTTTTCAACTCTTGATGACATTTTCCCCCACCAAAAAACTCTTCTCCGCGTCCAGCACTGATAGTTGTAGTCGCTCTTCTAAGAAGAGAGATGTAAAGCGAAAGAGGGCGACGGACAGTCAGTGCAGTCCAACTGAGGATCCGGAGGTCATCATAGTGGGAGCTGGGGTGCTAGGATCGGCCATGGCTGCTGTTCTGGCCCGGGATGGACGGCGGGTCACCGTGGTGGAGAGGGACATGAAAGAACCAGACCGAATAGTTGGAGAACTTCTGCAGCCGGGAGGATTTCGGGTACTCAAAGACCTTGGCCTGGAGGGTACTGTTGAGGGTCTGGATGCTCATGTGGTGAACGGTTATGTAATCCATGACATGGAAAGTAGGACAGAGGTGGAGATCCCATATCCCCAGCAGGAGAACTGCATTCAGGGTGGACGTGCTTTCCATCATGGGCGCTTCATCATGGGGTTGCGTCGAGCTGCCCTCGCTGAGCCTAATGTGAAGTTTGTGGAGGGAACAGTGACCAGCCTGGAGGAGGAGGAAGGTTGTGTGACAGGAATTCAGTACAGGGAGAAAGACACCGGGATGCTCAAGGAGGTTCGCGCTCCTCTGACTATAGTCGCTGATGGCTGTTTCTCCAAGTTCAGGAAGAATCTGGTTTCTGGGAAAGTTCGGGTGTCGTCGCATTTTGTTGGATGCATAATGAAGGACTCTCCTCAGTTCAAAGCCCACCATGCAGAGCTAGTTCTAGCTGATCCCAGTCCAGTGCTGATCTACCAGATCTCCTCCAATGAAACTCGTGTTCTGGTGGACATCAGAGGAGAGATGCCACGGGACCTCATGCAGTACATGACTGACAAAATCTACCCACAGCTACCAGAgcacttaaaggagccgttcaTGCTGGCACTGCAGAACGACCGGTTGAGAACGATGCCTGCCAGCTTTCTGCCACCCGCACCAGTCAATAAACAAGGGGTTCTGCTGTTAGGAGATGCGTATAACATGCGTCATCCTCTGACCGGCGGAGGCATGAGTGTTGTGCTGAATGACGTCTCCATCTGGAGAGACCTGCTCAAGAACATTCCTGACCTCTATGACAATACAGCTTTGCTCCAGgcGAAGAAGAAATTCCACTGGGAGCGGAAATCCTCTCACTCGTTTGTGGTGAACGTTTTGGCTCAAGCGTTATACGAGCTGTTTGCTGCGACTGACAAATCACTGCATCAGCTACGAAAAGCATGCTTTCACTATTTCAAGCTCGGTGGAGAATGCATCAATGGACCAATCGGGCTCCTGTCTGTGTTGTCGCCAAAACCCTTGACTCTGATTGGACACTTTTTTGCCGTGGCCCTGTACGCTATATACTTCAGCTTCAAGTCTGAATCCTGGCTCACAATACCACGAGCACTGGTCAACAGCGCAGCCATCCTGTACAGAGCCTGTGCCGTCATGTTTCCTCTCATATACTCGGAGTTACAGTACCTGGTTTACTAGAAAAAGAGACTGATTTTAAATTTGCTGCGACACATCTGCCTTTAGTGCTTACATCCAAGTGCCTCATTTACTTTGAGGGGAAAAAAGGGATTCATGTcagataaaacacaataaaaggaGCGAGTCTCAG

Function

symbol description
sqlea Predicted to enable squalene monooxygenase activity. Predicted to be involved in cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SQLE (squalene epoxidase).

GO:

id name namespace
GO:0016126 sterol biosynthetic process biological_process
GO:0008203 cholesterol metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004506 squalene monooxygenase activity molecular_function
GO:0050660 flavin adenine dinucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-071004-98 Predicted to enable squalene monooxygenase activity. Predicted to be involved in cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SQLE (squalene epoxidase).

Ensembl:

ensembl_id ENSDARG00000079946

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020210 True 2093 mRNA 0.49 11 43401005 43413293

Neighbor

gene id symbol gene type direction distance location
XLOC_010206 rnf144b coding upstream 8550 43368572 ~ 43392455 (+)
XLOC_010205 ccdc127a coding upstream 50500 43347966 ~ 43350505 (+)
XLOC_010204 mrpl32 coding upstream 54089 43344475 ~ 43346916 (+)
XLOC_010203 adam22 coding upstream 116066 43152727 ~ 43284939 (+)
XLOC_010202 dbf4 coding upstream 250516 43139504 ~ 43150489 (+)
XLOC_010208 NA coding downstream 273860 43687153 ~ 43687568 (+)
XLOC_010209 NA coding downstream 352686 43765979 ~ 43818565 (+)
XLOC_010210 dpys coding downstream 885609 44298902 ~ 44325688 (+)
XLOC_010211 CR925804.2 coding downstream 1192033 44605326 ~ 44605440 (+)
XLOC_010212 zgc:101716 coding downstream 1265009 44678302 ~ 44687969 (+)
XLOC_010201 NA non-coding upstream 276769 43119050 ~ 43124236 (+)
XLOC_010199 NA non-coding upstream 352726 43041505 ~ 43048279 (+)
XLOC_010198 NA non-coding upstream 499265 42897582 ~ 42901740 (+)
XLOC_010197 CR854827.2 non-coding upstream 522994 42876446 ~ 42878011 (+)
XLOC_010195 NA non-coding upstream 600274 42795604 ~ 42800731 (+)
XLOC_010213 CR925804.1 non-coding downstream 1291079 44704372 ~ 44705154 (+)
XLOC_010216 FP085399.1 non-coding downstream 1789797 45203090 ~ 45206236 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_02950348_02954214 SQLE, SQLEA coding CI01000027 null 2950106 ~ 2954214 (-)