XLOC_010227 (otud7b)


Basic Information

Item Value
gene id XLOC_010227
gene name otud7b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 45930962 ~ 45982657 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00020236
GCCTTGACGTTGTTGTTGTGGGAGTAAGAATGTACTTAGTCGTCAAGTCTTTATAAGACAAAAAGCAAGACGTTTCTTTGATATTTACATAACACAACAATAGCACACAACCCAAGAGGAAGTATTTTCTGCGAGCGAACAGCCAAGAGTGGGAGGAAATGAGAGAGAAATTCCGCGAGGCCGCTCGAGGTGTGGCCCAAACTGTGCTGTTGCTGTGAGGGAGAATTGCTCTCctgttttttctctctcctgATGCCCCCTTCTGCACTGTaaattcatgatcacatgactTTGGATATGGACGCAGTCCTGTCCGACTTTGTCCGTTCTACTGGAGCTGAACCCGGACTGGCCAGAGACCTGCTGGAGGGAAAGAATTGGGACCTCTCAGCTGCACTGAGTGACTTTGAGCAGCTGAGACAAGTGCATGCTGGGAGCCTCTCATGCAGCTTTGTTGAGGAGAGTGAGTACCCCTCCATTGAGAAGGAGATGGCACGGACAGGACGGCCCCTCTTACATCGACAAGATGAGGCTGTTCAAGCAGCCACAGAGAAGAGACTGTCGAGAGGAATCTCTCACGCCAGCTCCACCATCGTCTCCTTGGCCCGCTCGCACGTGTCCAGTACAGGAGGAACCAACGAGCAGCTTCTGGATACCCCGCTCTGCACATTCCAGTTGCCGGACCTCACCGTTTACAGAGACGACTTCCGCGGCTTCATCGAGAGAGATCTCATTGAGCAGTCTATGATGGTGGCTCTGGAGCAAGCTGGTCGGTTGAACTGGTGGACTCGTTTGGGGACAGGCTGTCAAAGTTTATTACCTCTAGCCACAAGTGGTGATGGGAATTGCCTGTTACACGCAGCCTCTCTGGGAATGTGGGGCTTCCATGATCGAGACCTGATGCTGCGGAAGTCTCTCTATGCACTGATGGATCATGGGCAGGAAAGGGAGGCTTTAAAGCGAAGGTGGAGATGGCAGCAAACCATGCAGAACAAAGAGtcggGACTGGTTTACACAGAGGAAGAGTGGCAGAAAGAGTGGAACGAGTTGTTAAAACTGGCATCTAGCGAACCAAGGATACACTACAGCACCAATGGCAGCAGCGgTGCCGAATCGCAGGAGGAGCCAGTGTATGAGAGCCTGGAGGAGTTTCATGTGTTCGTTCTTGCTCACGTGCTCCGCAGGCCCATAGTCGTGGTTGCTGACACCATGCTACGGGACTCTGGAGGAGAAGCTTTTGCACCAATTCCTTTCGGAGGGATTTATCTGCCTTTGGAAGTACCAGCCAACAAGTGTCACCGCTCCCCTTTGGTTTTGGCATATGACCAGGCCCATTTCTCTGCCCTGGTCTCAATGGAGCAGAAAGACAGTTCCAAAGAACAAGTGGTGATCCCTCTGACAGATTCAGATCATAAGATGCTGCCTTTGCACTTTGCTGTGGATCCTGGGGCAGACTGGGAATGGGGCAAAGATGACAATGACAATGTGATGCTAGCAAGTGTAACCTTATCTCTGGAGGCCAAGCTCCATCTGCTGCATTGCTACATGACTGTCACCTGGCTTCCTCTGCCCTGTGAGGTACAGCAGGCTCCACTGGCACAGCCAGAGTCACCAACAGCATCTGCAGGAGAGGATGCCCGCACCCCACCAGACTCTGGAGAGTCTGATAAGGAGTCCGTTAGTAGCAGTTCCAATGGCAACGGTGACAGCAGTACTACTGGAACCAGTGGGACAACAGGCAAAACCAGTGGTGGATCTTCCAGTTCCTCAAGCTCATCCAGCAACAGTTCAGGAGGAACCACCGGCACAATAGGAAAGGAGAAGGGGAAGAAAGATAAAGAAAAGGATAAGGACAAAGACAAGAAGCGTGCAGACTCTGTTGCCAACAAACTGGGAAGCTTTGGCAAGAGTCTGGGCAGT
>TCONS_00020237
GATATTTACATAACACAACAATAGCACACAACCCAAGAGGAAGTATTTTCTGCGAGCGAACAGCCAAGAGTGGGAGGAAATGAGAGAGAAATTCCGCGAGGCCGCTCGAGGTGTGGCCCAAACTGTGCTGTTGCTGTGAGGGAGAATTGCTCTCctgttttttctctctcctgATGCCCCCTTCTGCACTGTaaattcatgatcacatgactTTGGATATGGACGCAGTCCTGTCCGACTTTGTCCGTTCTACTGGAGCTGAACCCGGACTGGCCAGAGACCTGCTGGAGGGAAAGAATTGGGACCTCTCAGCTGCACTGAGTGACTTTGAGCAGCTGAGACAAGTGCATGCTGGGAGCCTCTCATGCAGCTTTGTTGAGGAGAGTGAGTACCCCTCCATTGAGAAGGAGATGGCACGGACAGGACGGCCCCTCTTACATCGACAAGATGAGGCTGTTCAAGCCACAGAGAAGAGACTGTCGAGAGGAATCTCTCACGCCAGCTCCACCATCGTCTCCTTGGCCCGCTCGCACGTGTCCAGTACAGGAGGAACCAACGAGCAGCTTCTGGATACCCCGCTCTGCACATTCCAGTTGCCGGACCTCACCGTTTACAGAGACGACTTCCGCGGCTTCATCGAGAGAGATCTCATTGAGCAGTCTATGATGGTGGCTCTGGAGCAAGCTGGTCGGTTGAACTGGTGGACTCGTTTGGGGACAGGCTGTCAAAGTTTATTACCTCTAGCCACAAGTGGTGATGGGAATTGCCTGTTACACGCAGCCTCTCTGGGAATGTGGGGCTTCCATGATCGAGACCTGATGCTGCGGAAGTCTCTCTATGCACTGATGGATCATGGGCAGGAAAGGGAGGCTTTAAAGCGAAGGTGGAGATGGCAGCAAACCATGCAGAACAAAGAGtcggGACTGGTTTACACAGAGGAAGAGTGGCAGAAAGAGTGGAACGAGTTGTTAAAACTGGCATCTAGCGAACCAAGGATACACTACAGCACCAATGGCAGCAGCGgTGCCGAATCGCAGGAGGAGCCAGTGTATGAGAGCCTGGAGGAGTTTCATGTGTTCGTTCTTGCTCACGTGCTCCGCAGGCCCATAGTCGTGGTTGCTGACACCATGCTACGGGACTCTGGAGGAGAAGCTTTTGCACCAATTCCTTTCGGAGGGATTTATCTGCCTTTGGAAGTACCAGCCAACAAGTGTCACCGCTCCCCTTTGGTTTTGGCATATGACCAGGCCCATTTCTCTGCCCTGGTCTCAATGGAGCAGAAAGACAGTTCCAAAGAACAAGTGGTGATCCCTCTGACAGATTCAGATCATAAGATGCTGCCTTTGCACTTTGCTGTGGATCCTGGGGCAGACTGGGAATGGGGCAAAGATGACAATGACAATGTGATGCTAGCAAGTGTAACCTTATCTCTGGAGGCCAAGCTCCATCTGCTGCATTGCTACATGACTGTCACCTGGCTTCCTCTGCCCTGTGAGCAGGCTCCACTGGCACAGCCAGAGTCACCAACAGCATCTGCAGGAGAGGATGCCCGCACCCCACCAGACTCTGGAGAGTCTGATAAGGAGTCCGTTAGTAGCAGTTCCAATGGCAACGGTGACAGCAGTACTACTGGAACCAGTGGGACAACAGGCAAAACCAGTGGTGGATCTTCCAGTTCCTCAAGCTCATCCAGCAACAGTTCAGGAGGAACCACCGGCACAATAGGAAAGGAGAAGGGGAAGAAAGATAAAGAAAAGGATAAGGACAAAGACAAGAAGCGTGCAGACTCTGTTGCCAACAAACTGGGAAGCTTTGGCAAGAGTCTGGGCAGTAAGCTGAAGAAGAATGTGGGAGGCCTAATGCCAGGGAAGAATGCAAGTGGAACTGGAGGCAAACAAGAGGGTCAGGAGAAGAAGAAAGGCTCTCTGAGAGGCCGTAAGGGCAGTAAGGACAGCTCTCCTTCCATTCAAACTGGCTCCGAGGACTCTGGGAAAGGCTCACCCTCCTCAACCAGTGAGCGGCAAAATGGAGGCTACTCTTCGGAAAGTGACCCTTTCAAATACAGCTCGGATGTGAAAGTTAGTCTTAGCATCCTTCGATCTGCTATGCAAGGTGAAAGGAAGTATATCTTCTCTGCGCTCCTTACCACCAGCAACCGGCAGCCGTTCCAAGAAGAAATGATTCAGCGCTACCTGGTCGATGCAGAGGAACGCTTTCATGCAGAACAGGAACAGAGAAGGGAAGCGGAACGGAAAGCAGCAGGAGGTCTTGCCTCGACTACTGGACCCCAGATGAAGAAGGACGGACCTGAGCTGAGCTACAGAGGTTTTGAAAGCAAAGAGGAAGTTACCGATAGCTCGCCTCCGAATTTTAATGCGTTGAAATCATCCTCTTTCAGTCCTGTGATGTACTCTGGTGTGGTCCCAATCCCGAGGCACACCTTTATTGACCATTCTCCTTCCCCAATGACACAGCATCTCCATATGCATCATGGTTATATGGATACACGACGGCAACTGGCAGGAGGATCACCGTCATCTTACCCAGGCCTGCCATCTTATGCTACTCTCCCCAGACATTGCCCTCTAGCACAGGGCCCGCCTCATGCTCAGTACCACCCGCCCTCCGCCAGCTTGGGAAGCCCATCCCGTATCATCACCCCCTGCTTGACGTCTTTTCCTCAAGAGCATGACCCAACTGATTATCCAAGCGAACCCAGCGGAGCCTACACAAACGGATTGCGGGACTTGCGCTCTACTTTGGACAGTCGAAACGGGCCGATGCCCGTGAGGCATTACTCCTTAGGAAGTGCGGGTGGCCTGGCCAACCTGCAGTCCAGCAAATGCCGAACGCCTACGTGCAATTACTACGGCCACCCGGAGACAGGCAACTACTGCTCGTACTGCTACAGAGAGGAACTGAAGAGACGGGAAACAGAGCCAGCCATCCACAGGTTTTGAACAGACAACCGTTGGCCTGTTCCTCTCATAATGGACTCATTGGAGCCTACAGTGTGAGCCACATCATATCCTATTTGTGTGGATCTTGCTTTAAAACAATAGATCGGCCTTTCTGAACCAGGTTATTAGGACTCTGTGTCCACAAATTATGGCCATTGTGGATATGGGACTGCTGTTGTGTTACATTTGCTGTGGCTCATAGGCAGGAGCTTTAAGCTCCTCCCACATTAGCTTGATGTGGTCATCCTCTTACCTGTCTCTTTGTCTCCTCCTTGTGGTGAGAATGTAGAGTACAGGCAATAAACATTTGAGTGTAACGTGCGTCACACAAACACGCCGCATACCCTAAAATACACATTAAGCACAACCAGAAAACGCGTATTTATATCAGCTGCATTTGTatacaaaataagacatttcatGTAGGATTTTAGCTGCAATCCATGTAAGACTTGCCATATTGCGAGTGTAAGGCAACGACACACTGTTAACTTCAAGTGAGTGTTATTCACATTAGCCCAACGCTACAGTACTTTAACTTGCACCCTTTGGAAAGCCATACCTGGTTGGCTTAAATGAGCTAATATGGTGCTTTTTATTGCTTGTTCAACTGACGGAGCTAAACCTTGACAGTCAAAGGTTTCGCTTGAGGTCTTCACATGTCCTTATTAAAAGTCCCAGTTGTTTA

Function

symbol description
otud7b Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent deubiquitinase. Acts upstream of or within Notch signaling pathway. Predicted to be active in cytoplasm and nucleus. Orthologous to human OTUD7B (OTU deubiquitinase 7B).

GO:

id name namespace
GO:0007219 Notch signaling pathway biological_process
GO:0070536 protein K63-linked deubiquitination biological_process
GO:0071108 protein K48-linked deubiquitination biological_process
GO:0035871 protein K11-linked deubiquitination biological_process
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process biological_process
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding molecular_function
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060616-1 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent deubiquitinase. Acts upstream of or within Notch signaling pathway. Predicted to be active in cytoplasm and nucleus. Orthologous to human OTUD7B (OTU deubiquitinase 7B).

Ensembl:

ensembl_id ENSDARG00000017220

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00020236 False 1920 mRNA 0.52 12 45930962 45980841
TCONS_00020237 True 3648 mRNA 0.51 12 45931041 45982657

Neighbor

gene id symbol gene type direction distance location
XLOC_010226 rbm8a coding upstream 885 45922175 ~ 45930077 (+)
XLOC_010225 NA coding upstream 118638 45787042 ~ 45812324 (+)
XLOC_010224 paqr6 coding upstream 148355 45739193 ~ 45782607 (+)
XLOC_010223 smg5 coding upstream 196749 45693413 ~ 45734213 (+)
XLOC_010222 CU459129.1 coding upstream 264110 45666735 ~ 45666852 (+)
XLOC_010228 NA coding downstream 5774 45988431 ~ 45990842 (+)
XLOC_010229 mtmr11 coding downstream 18299 46000956 ~ 46104010 (+)
XLOC_010230 sv2a coding downstream 129192 46111849 ~ 46202705 (+)
XLOC_010231 bola1 coding downstream 223036 46205693 ~ 46209855 (+)
XLOC_010232 NA coding downstream 287067 46269724 ~ 46270888 (+)
XLOC_010220 NA non-coding upstream 239742 45455980 ~ 45691220 (+)
XLOC_010221 CU062666.1 non-coding upstream 342632 45588214 ~ 45588330 (+)
XLOC_010217 FP016247.1 non-coding upstream 657243 45217307 ~ 45273719 (+)
XLOC_010233 NA non-coding downstream 294287 46276944 ~ 46282156 (+)
XLOC_010240 NA non-coding downstream 572737 46555394 ~ 46569152 (+)
XLOC_010241 NA non-coding downstream 573686 46556343 ~ 46569484 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_01466387_01475758 OTUD7B coding CI01000027 null 1465547 ~ 1475758 (-)