CI01000071_00792254_00802384 (SLC6A4B, SLC6A4)


Basic Information

Item Value
gene id CI01000071_00792254_00802384
gene name SLC6A4B, SLC6A4
gene type misc
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000071
NCBI id null
chromosome length 5214881
location 791346 ~ 803317 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000071_00792254_00802384.mRNA
GCATAAAAAACAATAAACAGAATGAAGGTTCTGCTGGAAAATTAATCTTTGTTTAACTTGTCACAATCATTTCTGTCAGTTCTACTTGATAAGTTACCGTAGCTTTCTTCATCAAAAATTAAATTCAGAGTTCTACTTATCACTACAGTTTATAATTTGAGACCACCATGAATTTTGCCCAAAACAATTTTAGGACAAAATTGTTTACAGTATGTTGGTTTCTATAGCTATAAGGTGAACATTAGCTGGTTTTAGAATTGTGGGCTAATTATCTAGTTGACCATCTACTATGATCATATTTATCATATTAAATATGAACAGTACCTGGTTTGTTACTGGTCCAACAAGTTCTATTAGCTTTAATTCCAGCAGAGGGAAATAAGAAAGTGTTACATTTACTAAATTATATATATATATATATATATATATATATGGTATTTCTGAAACAATTGCAATATTTCCATTAAAAGTACACATTGACCATACTTTTATTTCCTCTTCTTCATAATATTGTCGTTGTTACGTTGACAAATAGAGCAATATTTCTTGAGGACTCAAGCGCGCTCTTGGAAAAGTCTATATTTGAATGATAGCAGTGCTGGGCGCGCGGGATGTCAGGGGTGAGTGATGGTGTCGCGCGCATCTCCCGCGTGTAATCTCATTCGATCACAGCTCTCGCGCTCAGGTGGGGGACTCTTGGTTAATCCTGAAGCTCTTACTCCCACCAGCAGGGAAATCAACCACAGCAGCATGCTGCGGTCCCCCGCACAGACTCTTTTGACCGCACGTCGAGCATAATCCAAAAAACTATTCTTACTACTTTTTACATTTTGAAAAACTCACAAAAGCCATTTCTTACGTAGTCTTTTAGTACTTCTGCAGTTTGCCAAGCCACCGGACCACCGAAGATGCCCCACCAAGAGCAAGTGATCGCTCACGGGAACCTCTGCGCCCCGGGTCCTCCAAACAACGCCGGGTACAACAGCAACCCGGGGCCCGTCATCATTCAGACAGAATCCCGCGATAAATGGAGCAAAAAAATGGATTTTCTTTTATCAGTTATTGGGTTTGCGGTAGACCTCGGTAACGTTTGGAGATTTCCATATATCTGTTATCAAAACGGCGGTGGTGCATTTCTTATTCCTTATGTCCTGATGGCTGTATTTGGTGGGGTGCCACTTTTCTACATGGAGTTAGCTCTGGGACAGTTTCACAGAACAGGTGCCATATCCATATGGAAACATATTTGCCCGATTTTTAAAGGTATTGGTTTCGCCATCTGCATCATTGCACTGTATGTGTCCTTCTACTATAACACCATCATCGCCTGGGCTCTGTTCTACTTCTACTCCTCGTTCAGCAGCACTCTGCCCTGGACCAGCTGTGATAATGAATGGAACACCGAAAACTGCACTAACTACTTCGGGAAAGATAACGTAACCTGGACAAACTATTCACGCTCACCTGCCGAGGAGTTTTACACGAGGAATGTCTTGGCAGTTCATGAATCATCTGGGCTTGGGAATGTGGGATACATTCGCTGGCAGCTCATGCTCTGCCTCTTCCTCATCTTCACCATTGTCTACTTCAGCCTGTGGAAAGGAGTCAAGACTTCAGGAAAGGTAGTGTGGGTGACTGCCACCCTGCCGTACGTAGTGCTGTTGATTCTTATGATCCGTGGTGCCACCTTGCCAGGAGCGTGGAAAGGAGTGGTGTTCTACCTCAATCCCAAATGGGAAAAACTGCAGGAGACCAGCGTATGGGTAGATGCAGCTGCACAGATCTTCTTCTCCCTTGGTCCTGGTTTTGGCGTTCTGCTTGCCCTGTCCAGCTACAATCCCTTCAACAATAACTGCTACAGAGATGCTATTGTAACCAGTCTGGTGAACTGCCTGACAAGTTTTGTGTCAGGATTTGTTATTTTCACTGTCCTGGGATATATGGCTGAACAGAGAAATGTAAACGTTGAGGACGTAGCCAAGGACAAAGGACCGAGTCTGCTCTTCATCACATATCCAGAAGCCATCGCAAACATGGTTGGGTCGACTTTCTTTGCCATCATCTTCTTTGTAATGATGATTACGCTTGGATTGGACAGCACTTACATTATTATCAGCTCACTGCTGAACCCTCAACCCCTCACGCTATTCGACTACAAGTTCCCAGACTGGAGCATCACGGTTGGTTTTGTCATTGGAGCTTCCTCCTTCATATGGATCCCCATATACATGGTGTACAAGCTCGTGTGGACCCCAGGCTCTCTTAAACAGCGCCTTGCTGTATGTCTGCGACCGGAGAGAACACTGCCAGATATCCACGCTGACAGTATGGGGTTAAGTCCTGTACCTTAGACCACTGAGAGAAAAACACAATGTGCATAAAAAGGCCACATATAGTGGGTTACATGTGTCCACAGCAAACTAAGAGTTTATTATAAGGGTAAAGAGCAACTTTGGCATAGTTTCAGGGATTTGTCCATTTGAAATCACCAATCAAGAATGATCTATTTGAAAGTGATGTACAATTAGATTTAATATAAAAAAAATTAAAACTGATGTTCACTTTAAGTTAAAGTCCCTTATTTAACATGCTGTGCAATTTACAAATGGTTGATGTTCTTTTTTTAATTTAAGGTTTACGTATAAAATGAAGAGTTCAGTGGTATTTTTTACATTGTAAGTCATATATACATTCCAGGTCACAGAACGTTTTTTGACATACATGCAAGTGAGATTACCTCATTGTGAGAAATTCAGCCAATGAGAAAATGAGAACAGAGAACTTCATATACATTTCTCGCTCATTTATTTATTTATTTTTTTTAAGAAATAACTATTGTCAAGATTTAATCATTATGGTGTTTTCTGCCTTAACTCTGCCTAAATATTGTAGCTACTTTATGTCAAAACTTTGTTAAACCTGTATTGATATTGTGCCTCACCAAGAAAAGGAAAAATGACAAAAATAAGGTTTTCTTCTGTTCCTCATTTGGAACTAACACTACATGACTGTTTGAAATGTTCATTCTCTAACAGAACTTGAGCCCAAATCCTAGCTATGTGTAACGTGTTAATTTTCTTCCCACATTTTTTCCAA

Function

symbol description
slc6a4b Predicted to enable serotonin binding activity and serotonin:sodium symporter activity. Predicted to be involved in serotonin uptake and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; alexithymia; anxiety disorder (multiple); heart disease (multiple); and mental depression (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4).
slc6a4 Enables serotonin:sodium symporter activity. Involved in regulation of thalamus size; response to toxic substance; and serotonin uptake. Acts upstream of or within monoamine transport. Located in endomembrane system; membrane raft; and plasma membrane. Implicated in several diseases, including alcohol use disorder; alexithymia; anxiety disorder (multiple); heart disease (multiple); and mental depression (multiple). Biomarker of brain disease; chronic fatigue syndrome; diverticulitis; and leishmaniasis.

NR:

description
serotonin transporter b, partial

GO:

id name namespace
GO:0051610 serotonin uptake biological_process

KEGG:

id description
K05037 SLC6A4, SERT; solute carrier family 6 (neurotransmitter transporter, serotonin) member 4

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000071_00792254_00802384.mRNA False 3096 mRNA 0.41 10 791346 803129

Neighbor

gene id symbol gene type direction distance location
CI01000071_00707882_00708320 NA coding upstream 82071 706888 ~ 709581 (+)
CI01000071_00544529_00545575 FOXD1 coding upstream 245505 544249 ~ 545841 (+)
CI01000071_00531716_00534432 ANKRA2 coding upstream 256384 530382 ~ 534962 (+)
CI01000071_00335696_00339048 NA coding upstream 451773 335049 ~ 339573 (+)
CI01000071_00329399_00333840 ENC1, CCIN coding upstream 456862 329399 ~ 334484 (+)
CI01000071_00807216_00807677 NA coding downstream 3702 806831 ~ 808142 (+)
CI01000071_00825247_00853236 GIT2A, GIT2 coding downstream 21810 824939 ~ 853754 (+)
CI01000071_00867024_00871868 NA coding downstream 63712 866841 ~ 873319 (+)
CI01000071_00880705_00897817 TRPV4 coding downstream 77576 880705 ~ 898445 (+)
CI01000071_00923006_00927912 NA coding downstream 119623 922752 ~ 928488 (+)
G280413 NA non-coding upstream 15235 737965 ~ 776111 (+)
G280411 NA non-coding upstream 63976 726653 ~ 727370 (+)
G280341 NA non-coding upstream 142690 648064 ~ 648656 (+)
G280373 NA non-coding upstream 230124 560987 ~ 561222 (+)
G280449 NA non-coding downstream 95689 898818 ~ 899610 (+)
G280477 NA non-coding downstream 99738 902867 ~ 903174 (+)
G280478 NA non-coding downstream 100654 903783 ~ 904013 (+)
G280479 NA non-coding downstream 101503 904632 ~ 904864 (+)
G280443 NA other downstream 102088 905217 ~ 922096 (+)
CI01000071_01374449_01376813 NA other downstream 571454 1373996 ~ 1377670 (+)
CI01000071_02815324_02834097 NA other downstream 2001515 2815127 ~ 2835525 (+)
G282080 NA other downstream 2252955 3056084 ~ 3056531 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_030960 slc6a4b coding NC_007116.7 CM002889.2 19969794 ~ 19988772 (-)