CI01000306_08868661_08869685 (GPX1A, GPX1)


Basic Information

Item Value
gene id CI01000306_08868661_08869685
gene name GPX1A, GPX1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000306
NCBI id null
chromosome length 11491657
location 8868182 ~ 8870046 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000306_08868661_08869685.mRNA
ACGAACTTTTATGCAGGGGTTGGAAAGCAATATCGTCGTTTGACAAAAGATGGCGGTGTTTAACAGCGTTTACCTCCTGCTGCCCTGGCACGAGACAGCACTTCCTTGAATTGTATACGCAGTTCCCTCCCCCTTGACTCAAGGTTCAACTGAAGGTTTATAAAACAAATAGCATTTTGCATTTCGAGCTACAGAGTTAACTGCGTGTTCGAGCATGACAGGGACCATGAAGAAGTTTTATGATCTGTCCGCCAAGCTTTTGTCAGGGGACCTCCTGAATTTTTCGTCTCTCAAAGGTAAAGTTGTGCTTATTGAAAATGTGGCGTCGCTTTGAGGCACAACAGTCAGGGATTACACTCAGATGAACGAGCTCCACAGTTGTTATGCTGATCAGGGGCTGGTTATTCTGGGCGCTCCCTGCAACCAGTTCGGACATCAGGAGAACTGCAAGAATGATGAAATTCTGAAATCTCTGAAGTATGTCCGTCCGGGAAATGGCTTCGAGCCCAAATTCCAGCTTCTGGAGAAGCTGGAAGTGAATGGTGAGAACGCCCACCCTCTGTTTGTGTTCCTGAAAGAGAAGCTGCCTCAACCCAGTGATGACGCTGTGTCCCTGATGGGTGATCCCAAATTCATCATCTGGAGTCCCGTGAACAGGAATGACATCGCCTGGAACTTTGAGAAGTTCCTCATTGGCCCGGACGGGGAACCGTTCAAGCGGTACAGCAGAAGGTTCCTCACCAGCGACATTGAAGCAGATATCAAAGAGCTTCTCAAGAGGACGAAGTAAATCTGGCAGGCAGCCTTCTAGTGTTTGGCAACGCAAGATAGACCGTCCACTGCCTATCACATGAAGCCATAAGATTGTTGTTTGATATAAGCCGACTGTGCAGACATGATTAAAGTGCGACTGTTTTTTAGACTTTTTACTTAATGAAGATGCTTCCTAAAACCTTTCTGAGGGAAGTTTCTGATGTAACTGTAAAGGTTTATTATAATAGTTGTGTTTTATCCATGAATTGCACAGCTCAGGTTTTGTCTTTCAACCGTTAACTGAAAATAAAAAATAAAAAAATTCGATTGTTCCTTATTTCACAATTTACAAAACAAAAAACAGAAGCAGTTCATATGACAAACCTCAGCCTCACTTTTTCACTTCCACATTTTTTTTATTTTAAGAAAATTTTCCCCCTCTGTGCCTTTTTTAAAGAAAAACTTAAGTGCTATGAGAGTTATAATGCCTAACGAATTATTCTCTAACTAAATAAA

Function

symbol description
gpx1a Predicted to enable glutathione peroxidase activity. Predicted to be involved in several processes, including glutathione metabolic process; hydrogen peroxide catabolic process; and response to selenium ion. Predicted to act upstream of or within response to oxidative stress. Predicted to be active in cytosol and mitochondrion. Is expressed in Kupffer's vesicle; digestive system; muscle; optic tectum; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Orthologous to human GPX1 (glutathione peroxidase 1) and GPX2 (glutathione peroxidase 2).
gpx1 Enables SH3 domain binding activity; glutathione peroxidase activity; and phospholipid-hydroperoxide glutathione peroxidase activity. Involved in several processes, including UV protection; icosanoid metabolic process; and negative regulation of apoptotic process. Located in mitochondrion. Colocalizes with Lewy body. Implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Biomarker of Huntington's disease; artery disease (multiple); diabetic angiopathy; inflammatory bowel disease (multiple); and nephrosis.

GO:

id name namespace
GO:0006979 response to oxidative stress biological_process

KEGG:

id description
K00432 gpx, btuE, bsaA; glutathione peroxidase

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000306_08868661_08869685.mRNA True 1269 mRNA 0.43 2 8868182 8870046

Neighbor

gene id symbol gene type direction distance location
CI01000306_08864809_08865809 BRK1, BRK1.S, BRK1.L coding downstream 1969 8864794 ~ 8866213 (-)
CI01000306_08862287_08863560 SETMAR coding downstream 4622 8862119 ~ 8863560 (-)
CI01000306_08710919_08824478 ITPR1 coding downstream 43704 8709604 ~ 8824478 (-)
CI01000306_08699884_08701812 BHLHE40 coding downstream 164731 8698569 ~ 8703451 (-)
CI01000306_08690665_08696165 ARL8BA, ARL8B, ARL8BB, ARL8A coding downstream 172017 8690665 ~ 8696165 (-)
CI01000306_08950728_08950975 NA coding upstream 80583 8950629 ~ 8950975 (-)
CI01000306_08953503_08960561 RRP9 coding upstream 82994 8953040 ~ 8960782 (-)
CI01000306_08977329_08982584 NFYA coding upstream 107236 8977282 ~ 8983344 (-)
CI01000306_08986353_09011689 SORT1A coding upstream 115359 8985405 ~ 9012125 (-)
CI01000306_09013366_09014513 PSMA5 coding upstream 143025 9013071 ~ 9014513 (-)
G436337 NA non-coding downstream 40731 8826604 ~ 8827451 (-)
G436211 NA non-coding downstream 399582 8468362 ~ 8468600 (-)
G436198 NA non-coding downstream 424975 8442991 ~ 8443207 (-)
G436383 NA non-coding upstream 51568 8921614 ~ 8921940 (-)
G436386 NA non-coding upstream 53524 8923570 ~ 8923780 (-)
G436319 NA non-coding upstream 95656 8965702 ~ 8970622 (-)
G436308 NA non-coding upstream 102982 8973028 ~ 8973478 (-)
G436405 NA non-coding upstream 220084 9090130 ~ 9090826 (-)
G434338 NA other downstream 2001246 6866656 ~ 6866936 (-)
G434086 NA other downstream 2415931 6437406 ~ 6452251 (-)
G434016 NA other downstream 2506539 6355180 ~ 6361643 (-)
G433985 NA other downstream 2670972 6196107 ~ 6197210 (-)
G433670 NA other downstream 2826899 6041014 ~ 6041283 (-)
G436446 NA other upstream 786233 9656279 ~ 9671776 (-)
G436626 NA other upstream 964979 9835025 ~ 9836323 (-)
G436643 NA other upstream 1152102 10022148 ~ 10025375 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00017088 LOC100694221,LOC104965620,LOC102796420,LOC101486183,LOC103385919 coding CM030122.1 CM030122.1 44656787 ~ 44658914 (+)