CI01000310_01414325_01452698 (RUNX2, RUNX2A)


Basic Information

Item Value
gene id CI01000310_01414325_01452698
gene name RUNX2, RUNX2A
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000310
NCBI id null
chromosome length 5141163
location 1414325 ~ 1452698 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000310_01414325_01452698.mRNA
ATGCGCATTCCGGTAGATCCGAGCACCAGCCGCAGGTTCAGTCCGCCGTCCAGCAGCCTTCAGCCGGTGGCGGGGAAGATGAGCGATGTGCAGCAGGAGCCGAACGCGGCGGTGCCGAGACTCCGACAGCACGACAACCGAACCATGGTGGAAATCATCGCGGACCACCCCGCTGAGCTCGTGCGGACGGACAGCCCCAACTTTCTGTGCTCAGTGCTGCCGTCTCACTGGAGGTGCAACAAAACTCTCCCGGTGGCGTTTAAGGTTGTCGCTCTGGGAGATGTTCCTGACGGGACCGTGGTGACAGTTATGGCAGGAAATGACGAGAACTACTCGGCAGAACTGCGAAACGCCTCAGCTGTCATGAAGAATCAGGTGGCGCGTTTCAATGACCTGAGATTTGTTGGCAGGAGTGGAAGAGGAAAGAGCTTCACGCTGACAATCACAGTATTCACGAACCCACCGCAAGTGGCGACTTACCATCGAGCCATAAAGGTCACAGTGGATGGACCGCGGGAGCCACGAAGACACAGACAGAAACTGGAAGACCCCCCAAAACCGCCGCTGTTCTCCGAGCGCCTGAGCGAGTTAGAGCGTTTACGCCAGACCACCATGAGAGTTGCCGTGCAAACCCAGAGTCCCCGGCAGTCTCTCAACGCCACGCCGAACTCCTTCAATCCACAGGGGCAAACTCAGATCTCAGATCCGCGGCAGGCACAATCCTCTCCACCCTGGTCCTACGAGCAGCCGTACACTCCTTACCTGAGCCAAATGACGTCACCCTCCATCCACTCCACCACACCGCTGTCTTCCACCCGCGCCACCGGCCTGCCCACCATCAGCGACGTGCCAAGACGCCTCTCAGGTACGTCGGATCTCAGTCCGTTCTCGGCAGACCCACGGCAGTTTGAACGTCAGTTTCCTGGTCTGTCCACGCTCACAGAAAGCCGTTTCCCCAGTCCCAGAATGCACTATCCTGCGACGTTCACGTACACCCCCACGCCGGTCACCTCTGGCATGTCTCTGGGCATGTCCACCACCACCCACTACCACACCTACCTGCCTCCGCCATACCCCGGCTCCACCCAGAACCAAAGCGGGCCCTTCCAGACCAGCAGCACGCCCTATCTCTACTACGGCGCCTCATCCGGGTCGTACCAGTTCTCAATGGTGCCGGGCGGAGATCGATCCCCTTCCAGGATGCTGCCGCCTTGCACTAGCGCATCCACCGGCAGCACCCTCATCAACCCCAACCTGCCCAATCAGACGGACGGAGGCGAGGCGGATGGCAGCCACAGCAGCTCGCCAACTGTGCTCAACTCCAGCGGCAGGATGGACGAGTCCGTTTGGCGACCCTAT

Function

symbol description
runx2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including chondrocyte differentiation; ossification; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including cranium; fin; osteoblast; osteoprogenitor cell; and scale. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2).
runx2 Enables sequence-specific double-stranded DNA binding activity. Involved in osteoblast differentiation; positive regulation of osteoblast differentiation; and regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Biomarker of esophagus squamous cell carcinoma.

GO:

id name namespace
GO:0071773 cellular response to BMP stimulus biological_process

KEGG:

id description
K09278 RUNX2, AML3; runt-related transcription factor 2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000310_01414325_01452698.mRNA True 1359 mRNA 0.60 6 1414325 1452698

Neighbor

gene id symbol gene type direction distance location
CI01000310_01411744_01412226 NA coding upstream 1858 1411744 ~ 1412467 (+)
CI01000310_01394296_01394727 NA coding upstream 19417 1393089 ~ 1394908 (+)
CI01000310_01257447_01269508 NA coding upstream 144292 1257327 ~ 1270033 (+)
CI01000310_01207513_01226750 CDC5L coding upstream 187153 1207057 ~ 1227194 (+)
CI01000310_01196439_01199290 NA coding upstream 214948 1195700 ~ 1199377 (+)
CI01000310_01508712_01511125 FAM167A coding downstream 56014 1508341 ~ 1513341 (+)
CI01000310_01513690_01517791 NA coding downstream 60992 1513690 ~ 1518229 (+)
CI01000310_01564875_01571307 TDH coding downstream 112177 1564875 ~ 1572028 (+)
CI01000310_01588365_01597469 NA coding downstream 133794 1586492 ~ 1597486 (+)
CI01000310_01638700_01644396 FNDC4B coding downstream 186002 1638700 ~ 1644598 (+)
G439657 NA non-coding upstream 3720 1407707 ~ 1410605 (+)
G439628 NA non-coding upstream 46822 1357898 ~ 1367503 (+)
G439631 NA non-coding upstream 47896 1365631 ~ 1366429 (+)
G439565 NA non-coding upstream 152564 1261346 ~ 1261761 (+)
G439541 NA non-coding upstream 216255 1197604 ~ 1198070 (+)
G439679 NA non-coding downstream 70040 1522738 ~ 1523826 (+)
G439704 NA non-coding downstream 109623 1562321 ~ 1562554 (+)
G439721 NA non-coding downstream 151199 1603897 ~ 1604107 (+)
G439723 NA non-coding downstream 152153 1604851 ~ 1605069 (+)
G439741 NA non-coding downstream 198314 1651012 ~ 1651387 (+)
G439115 NA other upstream 723133 651976 ~ 653356 (+)
CI01000310_00648731_00650082 NAPB other upstream 764772 648566 ~ 650159 (+)
G439845 NA other downstream 458903 1911601 ~ 1912417 (+)
G440505 NA other downstream 1646719 3099417 ~ 3136328 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00004141 LOC107717234,LOC107594081,LOC107552040,LOC107653853 coding CM030121.1 CM030121.1 35239232 ~ 35248925 (+)