XLOC_013306 (mlc1)


Basic Information

Item Value
gene id XLOC_013306
gene name mlc1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 14928040 ~ 14941840 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00026318
ACTGGCTAAAACTGGCTGGCAGGGCAACGCGCTCAACTTTCTGTTCCAGGCTTTCGAAACGATCCAAAAAGTTTTTTATTGAATTGGAGTGAAGGGGACAGAGAGAAAAGAGGAGAACAAGAGGAAGAAGACAAAGATAAAGTACAACTAAAACCTTAGACTTCCTCGGGAGCAGGGGAACAGGGTGCCTCATGGATTTGAGGATGCAGCGAGAGGAGGCATCGGCTCAGGAAGTGTTCAGCTATGCCCAGATGTCCACCCTGGAGAGAAACAGCGGTGTAGGAACGCTGAGTCGGCATCTAGAGCGCGAGCGATTGGAGAGAGACGGCTACACGGTGGATGTCAGAGCCAGTGACCTGCAGCTGGATCAGCCTGGCCCGCTACATCCCTGCTTCAGCTACAGAGTCTGGCTTTACAGTGTGGTTGTAGGGAGCAGCTTGCTGATAGCGTCGGCTTTCTCGCTCTACATGGGTAATGTGTTTCCTGCTGCAATGGATTACCTGCGCTGTACTGCTGGATCTAGTATACCAGCAGCAGTGGTGAGCTTCGCCATTGCCAAGAACAGACAAGTCGCAGTCTCAGACTTTCAACTGGTCTATGTGTCTTCCTTTGCTGTGACAACCACGTGTCTGGTGTGGTTTGGCTGTAAACTGGCCATCAGTCCTTCAGCCATCAATATTAACTTTAACCTGCTCCTGCTTATTGTGCTGGAAGTGCTCACCGCCAGTACTGTTATTCTGTCAGCACGTTCAGTGGACAACTGCTGCAGTCACAGCAAGCCGGTGTCTGAAGGCCCAATGATTGTGACCCAAACATCGTTCCCCACTCGTCTTTTCAAGGCCTTCGCCGTAATTGAGCTCATAGTGGGCATCGCTGCAGTTTTTGGAGGAATTATTGCCCTCAATTTGGGCGCTCTTCTCCCAGAGCCTTACCTTTCTGTTACCTTCTTCTGGATTCTGGCAGCGTGTTTCCCCAGTGCCATCGCCAGCCATGTGGTGGCAGAAAATCCCAGCAAAAGTCTGGTGGAAATGCTGATTGCTATAAATAGTGTGACTTCACCACTGCTCTTCTCGGCCTCTGCATTCTTATCCAGCAGTGTGATTAGTTTTATTGAGATCTTTCTGCACGAAGTAGCATTAGCCAAGCAGTCGTATGACATCCTGCTGTTGGTcctgatgctgctgctgctggtgccAGCGGTGCTGACTTTAGCCACTATTATACAGTGTGCTTCCTACAAGAGCCAGGTCCGCATGGGTGCTAACGAATGGGACACACTGCGCAAAAAACACTGTGAGCAGCTGGCATCAAATGGCACATTAAGGGATTTCGACAAAGAAAAGGCCTGGAAGGCAGTGGTCGTCCAGATGGCCCAGTGACCAAAGTTGCTTG
>TCONS_00026319
GATGCAGCGAGAGGAGGCATCGGCTCAGGAAGTGTTCAGCTATGCCCAGATGTCCACCCTGGAGAGAAACAGCGGTGTAGGAACGCTGAGTCGGCATCTAGAGCGCGAGCGATTGGAGAGAGACGGCTACACGGTGGATGTCAGAGCCAGTGACCTGCAGCTGGATCAGCCTGGCCCGCTACATCCCTGCTTCAGCTACAGAGTCTGGCTTTACAGTGTGGTTGTAGGGAGCAGCTTGCTGATAGCGTCGGCTTTCTCGCTCTACATGGGTAATGTGTTTCCTGCTGCAATGGATTACCTGCGCTGTACTGCTGGATCTAGTATACCAGCAGCAGTGGTGAGCTTCGCCATTGCCAAGAACAGACAAGTCGCAGTCTCAGACTTTCAACTGGTCTATGTGTCTTCCTTTGCTGTGACAACCACGTGTCTGGTGTGGTTTGGCTGTAAACTGGCCATCAGTCCTTCAGCCATCAATATTAACTTTAACCTGCTCCTGCTTATTGTGCTGGAAGTGCTCACCGCCAGTACTGTTATTCTGTCAGCACGTTCAGTGGACAACTGCTGCAGTCACAGCAAGCCGGTGTCTGAAGGCCCAATGATTGTGACCCAAACATCGTTCCCCACTCGTCTTTTCAAGGCCTTCGCCGTAATTGAGCTCATAGTGGGCATCGCTGCAGTTTTTGGAGGAATTATTGCCCTCAATTTGGGCGCTCTTCTCCCAGAGCCTTACCTTTCTGTTACCTTCTTCTGGATTCTGGCAGCGTGTTTCCCCAGTGCCATCGCCAGCCATGTGGTGGCAGAAAATCCCAGCAAAAGTCTGGTGGAAATGCTGATTGCTATAAATAGTGTGACTTCACCACTGCTCTTCTCGGCCTCTGCATTCTTATCCAGCAGTGTGATTAGTTTTATTGAGATCTTTCTGCACGAAGTAGCATTAGCCAAGCAGTCGTATGACATCCTGCTGTTGGTcctgatgctgctgctgctggtgccAGCGGTGCTGACTTTAGCCACTATTATACAGTGTGCTTCCTACAAGAGCCAGGTCCGCATGGGTGCTAACGAATGGGACACACTGCGCAAAAAACACTGTGAGCAGCTGGCATCAAATGGCACATTAAGGGATTTCGACAAAGAAAAGGCCTGGAAGGCAGTGGTCGTCCAGATGGCCCAGTGA

Function

symbol description
mlc1 Acts upstream of or within protein localization to cell surface. Located in cell-cell junction. Is expressed in nervous system and radial glial cell. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts 1. Orthologous to human MLC1 (modulator of VRAC current 1).

GO:

id name namespace
GO:0047484 regulation of response to osmotic stress biological_process
GO:0034394 protein localization to cell surface biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005911 cell-cell junction cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-050419-145 Acts upstream of or within protein localization to cell surface. Located in cell-cell junction. Is expressed in nervous system and radial glial cell. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts 1. Orthologous to human MLC1 (modulator of VRAC current 1).

Ensembl:

ensembl_id ENSDARG00000063026

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00026318 False 1392 mRNA 0.51 12 14928040 14941840
TCONS_00026319 True 1177 mRNA 0.51 11 14928053 14937211

Neighbor

gene id symbol gene type direction distance location
XLOC_013305 panx2 coding downstream 5168 14906570 ~ 14922872 (-)
XLOC_013304 trabd coding downstream 26560 14885545 ~ 14901480 (-)
XLOC_013303 selenoo1 coding downstream 48905 14863407 ~ 14879135 (-)
XLOC_013302 mapk12a coding downstream 67605 14844669 ~ 14860435 (-)
XLOC_013301 mtss1la coding downstream 91178 14772474 ~ 14836862 (-)
XLOC_013307 btbd11b coding upstream 14325 14956165 ~ 15104858 (-)
XLOC_013308 BX649610.1 coding upstream 94311 15036151 ~ 15036269 (-)
XLOC_013309 mterf2 coding upstream 206091 15147931 ~ 15155962 (-)
XLOC_013310 NA coding upstream 246177 15188017 ~ 15191812 (-)
XLOC_013311 tmem263 coding upstream 317548 15259388 ~ 15269272 (-)
XLOC_013384 BX323829.1 misc upstream 4600262 19542102 ~ 19542231 (-)
XLOC_013300 NA non-coding downstream 162157 14763903 ~ 14765883 (-)
XLOC_013294 BX950204.1 non-coding downstream 1383673 13544250 ~ 13544367 (-)
XLOC_013293 BX890576.1 non-coding downstream 1449818 13477102 ~ 13478222 (-)
XLOC_013291 BX511124.1 non-coding downstream 1640389 13281654 ~ 13287651 (-)
XLOC_013288 NA non-coding downstream 1813722 13077843 ~ 13114318 (-)
XLOC_013319 BX928740.1 non-coding upstream 646247 15588087 ~ 15588201 (-)
XLOC_013321 CR854977.1 non-coding upstream 933822 15875662 ~ 15875780 (-)
XLOC_013323 NA non-coding upstream 997421 15939261 ~ 15970573 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000013_07012984_07019146 MLC1 coding CI01000013 null 7012723 ~ 7019146 (+)