XLOC_016157 (ephb3a)


Basic Information

Item Value
gene id XLOC_016157
gene name ephb3a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 7923964 ~ 8017579 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031873
aaaaaaacatgcacaaataAAAGAACATAGCAGAGTATTCTACTTAGTGTGTAAGTTATCAGCGGTATCCCGCAGGGTTTTGTCATGGGACCAATAGAGCTTTTCGCCCCCCAATCATTCCTCGCAACTGACACTCCTCCGTGCAGTCGCAAAGAATCAACAGCTTCTTTCACAcggaggatgaggaggatgatGCCACACATGTAGAAGAGCATGATAGAGGAAGAGCATCCGTGGATTCCGTGGTCCGAATGAAAGACGCGAAGACAACCACACCAAAGCGGAGCTGTGCATTTTTCACaggctgtttttttctctctctcaaggCGTGAATTCGATCATGAATGCTGAGATTTAACGAGACTTTCTGTCCCGGTGACACATAGACAAAACGCTTCTTCATGTTGCATCCTCAAGCTTCATGACAATGGATTATTCGCTGTTATTATACAGCCTTTGGGTTCCCGTTATTCTCGCTGTTGAGGAGACTCTTATGGACAGCAGGTGGGCTACTACAGAGCTGGCGTGGACCACCTATCCTGAAAGCGGGTGGGAGGAAGTGAGCGGATATGATGACCACTTGAGCCCCATCAGGACTTACCAGGTCTGTAACGTGCTGGAGCCCAATCAGAACAACTGGCTCCGTACAGACTTCATTCCCCGTCGAGGAGTCCTCCGAGTCTACGTGGAGCTCAAGTTCTCTGTGCGGGACTGTGGCAGTATTCCCAACATCCCCGGTTCCTGTAAAGAGACCTTTAATCTGTTCTACTATGAATCAGACGGAGACATGGCCACGGCAAGCAGCCCACCGTGGAGGGAGAATCCTTATGTAAAGGTGGACACCATTGCCCCAGATGAAAGCTTCTCGTTGCTGGAGTCAGGAATCGTCAACACCAAAGTACGGAGCTTCGGCCCTCTTTCCAAAGCTGGTTTCTACCTGGCCTTCCAGGACCTGGGCGCCTGCATGTCTCTGATCTCAGCCCGGGTCTTCTTTAAAAAGTGCTCCACCTCCATTGCCAACTTCGCTGTCTTCCCAGAGACGGCCACTGGCGCCGAGGCCACCTCTCTGGTCATCGCTGCCGGAGCTTGTGTGCCAAACGCCGCCGAGGAATCTGTCCCTCTAAAGCTGTACTGTAACGGAGATGGCGAATGGATGGTTCCAGTGGGAGCCTGCACCTGCATGCCGGGATTTGAGCCGGCCAAGAAGGACACTCAGTGCCAGGCGTGCACTCCAGGGACCTTTAAGTCCAAACAGGGTGAGGGTTCTTGTATGCCGTGCCCTTCCAACAGCCGAGCCAGCTCTAGGGCATCCAGCGTGTGCCCTTGTCAAAGTGGCTACTACCGCGCTGACAGCGACCTCCCTGACACGGCCTGCACTACTGTTCCCTCAGCTCCATTAAACGTGATCTCCAGCGTCAACGAGACTTCGGTGTCCCTCGAGTGGTCCGAGCCTCGGGATTCGGGCGGTCGAGGGGACGTGGTGTATAACGTGGTGTGTAAAAAGTGTCTTCACGATGGTGGCTCTTGTGCGCGCTGCGATGACAATGTGGAGGTCTCGCCGCGTCGCCTGGGTCTGGCAGAGAGGCAGGCGGCAGTGAGGAATCTGCAggcacacacacattacagcttTGAGATTCAGGCTGTGAACGGCGTGTCCCCCAAGAGCCCGTCCAGCCCACAGTACACCACTGTCAATATCACCACCAATCAAGCAGCTCCGTCAGCAGTCCCCACCGTCCACTTAATGCGGGCCACAGCTGGCACTCTCAGCCTCTCCTGGCTGCCCCCAGAGCAGCCCAATGGCGTGATCCTGGATTATGAGATCAAGTACCAGGAGAGGGGAGAGTCCTTCTCTCATACGGTCACAGCTCAGCACACTTCTGCCAAAGTGGAGGGTTTGAAGGCTGGCACGGTGTACTCTGTGCAGGTTCGAGCTCGGACGGTAGCTGGGTATGGACGGTATAGCAACCCGGTGGATTTCAGTACAAGTCTTTATGATGACCCAGAGCGCTCCGTACAGGATCTGCTGCCTCTCATTGTGGGCTCTGCTTCAGCAGGATTTGTGGTCATCCTTGCCATGATAGTCATCGCTGTTGTCTGCCTGAGACGGCAGCGTACTGGATCAGAGCTGGAGTACACTGAAAAACTACAGCAGTACGTATCGCCTGGTGTAAAAGTTTACATTGACCCTTTCACCTACGAGGATCCGAACGAGGCAGTTCATGAGTTTGCCCGAGAGATTGACATCTCATGTGTGAAGATAGAAGAAGTCATTGGAGCAGGAGAGTTCGGGGAGGTTTGTCGGGGTCGACTCAAACAGGCTGGCAGAAAGGAAACAACCGTGGCCATCAAGACGCTGAAGGCCGGCTACACCGAGCACCAGAGGCGGGACTTTCTCAGTGAGGCCAGCATCATGGGCCAGTTTGACCACCCTAACGTTATCCATCTGGAGGGCGTCCTGACCAGGAGTTGTCCCGTCCTCATTGTCACAGAGTTCATGGAGAACGGAGCACTCGATTCATTCCTCAGACTGAACGATGGCAGGTTTACTGTAACGCAGCTGGTGGGCATGTTGAGGGGGATCGCAGCTGGCATGAAGTATCTGTCCGACATGAACTACGTCCATCGTGACCTGGCTGCCAGAAACGTGCTTGTCAACAGCAACCTGGTGTGCAAAGTGTCCGATTTTGGCCTCTCCCGCTTTTTAGATGACAACTCATCAGACCCCACCTATACCAGCTCATTGGGTGGGAAGATCCCGATTCGCTGGACGGCTCCCGAAGCTATCGCCTTCAGGAAGTTCACCTCTGCCAGCGACGTGTGGAGCTATGGCATTGTGATGTGGGAAGTAATGTCATTCGGAGAGCGGCCGTACTGGGACATGAGTAATCAAGACGTGATGAACGCAGTGGAGCAGGACTACAGGCTGCCTCCACCCATGGACTGCCCCGCGGTTCTGCACCAGCTGATGCTGGAGTGCTGGGTGAAGGAGCGCAACATGAGGCCGCGTTTCGGACAGATCGTCAGCACTCTCGACAAGCTCCTCCGCAACGCCGCCAGCCTTAAAGTGCTCACCAGTACACACTCAGGAGATCTCTGTCGAATTGGCGGGACTCTGCCGGGGCACCAAAGGAAGAGTATAGGAGATGCACAAGACATAAAACAACAAATGAGCCAAACTCTACCCATACGGGTTTGACTgattcaaaatacacacacaaaaaacacctgCTGAGCCTCCAGGCTAGCAACAACTGACTGGGACAATCAATAGAAAGCCCATGGAAAATGACTGGAGCCAACTATTGCTTGAAGAGCCAATGGAAAAACCTGTATACAATTTGAGACAGTGTCGCACCCCTTCCCAAGGAGCCTGTGGAAAACAGGCGTGTCCAATGGAAAACTGTATCGCAGCCTGCGTTTCGGCACCTGGGGATGCTGGGAAATCACAGCACATGTTAATTGGAATTCTGTATGATGGCGCCTCAGGCAACCGTCTTTGTTCTTCCCTCCCTTTTGCCATGACTTTCTTGTGTTTACACTGAATTCTCATTACATGGATTAAATCGACAACGTTTCTACTTCTCAGGTTCAgtttgcatgtgtgcatgtgtttctctactggcaaaaaaaaaaaaactaaaaaaacaatcACTTTCTTCCGGAACTCAAATCCCTTCCATACTCATTTGCCGAGGCCACAAACGATGAGACGGACTGGAGAATTATAAGCTAGCtgtaataatgtttaaataatgtattaaatgtacGCCGGGACCGTTTGATGTTGGCTAGAGGATATTTTGCCACTCTTTCTCCCTCAAAAATTCTTCTGATCTTTTCTTCATATTGAAGAAAGGACGAGAGGAGTGGAACAGATGAAACTTTCGGAAAGAGACGTTACAGAGAACGGAAGGTCCTATACGGACGAAAAACAAAGCGGACTGTTACAAATCAAGAAAGGTGTTTTATTTACCTCTGTTGTATTTCGTCTTCCATGAAACGCTCCCGAGACTGAGAGGTTTGTCCACGTGGAGGACATCGAGCTGTGATTTTAAGATTCCCATTTCCCCAGCTTGTAAGCGAGGGGGGAattgtgctgtgtgtatgtgtgtgtgtatgtgtacagtaTGCTCATGTGCGCTTGACCGAGCTGGTCAGGCTCTACAGCTTTACATGCATGCCATATTCAAAACTCAAAGCTTATCCGAAAGGTGAAACGACGACAGGTTGACTCGAGCTGTTGTTTGATGAATATTCCGCTTATTTGAATTCCGTCTGTTCAGATATGCATAACTATGTAAATAAATGCCTCATAAGAA

Function

symbol description
ephb3a Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; neuron projection development; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within nervous system development and protein phosphorylation. Predicted to be located in dendrite and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in several structures, including anterior neural keel; central nervous system; hypoblast; immature eye; and mesoderm. Orthologous to human EPHB3 (EPH receptor B3).

GO:

id name namespace
GO:0051965 positive regulation of synapse assembly biological_process
GO:0022407 regulation of cell-cell adhesion biological_process
GO:0034446 substrate adhesion-dependent cell spreading biological_process
GO:0033674 positive regulation of kinase activity biological_process
GO:0016477 cell migration biological_process
GO:0007275 multicellular organism development biological_process
GO:0043087 regulation of GTPase activity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0060996 dendritic spine development biological_process
GO:0060997 dendritic spine morphogenesis biological_process
GO:0050770 regulation of axonogenesis biological_process
GO:0007399 nervous system development biological_process
GO:0007411 axon guidance biological_process
GO:0007413 axonal fasciculation biological_process
GO:0016310 phosphorylation biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0042995 cell projection cellular_component
GO:0043005 neuron projection cellular_component
GO:0030425 dendrite cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005003 ephrin receptor activity molecular_function
GO:0005005 transmembrane-ephrin receptor activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004714 transmembrane receptor protein tyrosine kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-60 Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; neuron projection development; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within nervous system development and protein phosphorylation. Predicted to be located in dendrite and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in several structures, including anterior neural keel; central nervous system; hypoblast; immature eye; and mesoderm. Orthologous to human EPHB3 (EPH receptor B3).

Ensembl:

ensembl_id ENSDARG00000031548

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031873 True 4322 mRNA 0.51 16 7923964 8017579

Neighbor

gene id symbol gene type direction distance location
XLOC_016156 NA coding downstream 7577 7915351 ~ 7916387 (-)
XLOC_016155 si:ch211-38m6.7 coding downstream 78854 7831914 ~ 7845110 (-)
XLOC_016154 tbl1xr1b coding downstream 123262 7764671 ~ 7800702 (-)
XLOC_016153 b3gnt5b coding downstream 166691 7749394 ~ 7757273 (-)
XLOC_016152 dcun1d1 coding downstream 212442 7698446 ~ 7711522 (-)
XLOC_016158 pls1 coding upstream 42378 8059957 ~ 8111346 (-)
XLOC_016159 NA coding upstream 473009 8490588 ~ 8494716 (-)
XLOC_016160 si:ch211-71m22.1 coding upstream 568836 8586415 ~ 8611675 (-)
XLOC_016161 si:ch211-71m22.5 coding upstream 600237 8617816 ~ 8636175 (-)
XLOC_016162 CT027589.1 coding upstream 616661 8634240 ~ 8635132 (-)
XLOC_016148 NA non-coding downstream 375945 7546686 ~ 7548019 (-)
XLOC_016147 FO203364.1 non-coding downstream 429500 7487592 ~ 7494464 (-)
XLOC_016146 NA non-coding downstream 492374 7402491 ~ 7431590 (-)
XLOC_016141 AL953893.1 non-coding downstream 843039 7080302 ~ 7080925 (-)
XLOC_016165 NA non-coding upstream 818343 8835922 ~ 8840884 (-)
XLOC_016169 CR385076.1 non-coding upstream 1388979 9406558 ~ 9406675 (-)
XLOC_016176 CU633992.1 non-coding upstream 1670476 9688055 ~ 9688185 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000004_00150251_00175611 EPHB3, EPHB3A coding CI01000004 null 150251 ~ 176659 (+)