XLOC_017207 (myoc)


Basic Information

Item Value
gene id XLOC_017207
gene name myoc
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 15015557 ~ 15021628 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034275
GGATCAACGACCAATCAAAGCAAGAAGCTCCAACCAGCCCCTCGAAGGCAACGTTTAGCTTGAGCGAGAGAAAGTCAGTAGGAGCGAAAGATTGAAAAGACTCAGGTGAGAGGTCATTAGTGGAACGCCAGAGAAGTACGGGGCTCCGGTTACACTTGGAAGGTGAAAGGGAAGGAATAGATTAGTGCTAGAGCCGAAGAGGACCAGGAAGGACAAGTGAGCTGCAAGTCACCACTGCATTAAACCTTGGACAAGGAGCTTCAGGCAACAGTAGAAAGAAGTTATCTGTGGTCCACCCCAACATGTGGTTTTTAGCAGTGTTGTGGATTTCTTCCCTGCTGATGGGATCCCAGGTTCAGAGCAGTGCTAACCTTCGTCGAGCAAATGCTGGGAATGGTCGCTGTCAGTACACCTTTATGGTGGACAGCCCTACTGAGGCCAGCTGTCCATCACCAGGTTCAACTCCTGAGATGGAGGCTCTGATGTCTCGCCTGGGGCTGCTAGAGGCACTGGTTGCTCGTCTCGTAGGAGGGGAAGCCATGCCAGAATCATCACAGAGCTCGGGATCTGGCCTTCAGGACTCTTACAACCAGGTGATGGGGGAGAACGCGCAGCTCAAGAGAGAAAAGCAGAGACTAGACAGACAAGTTCAGGACCTGCAGCAGAGGATGGAAGAGCTCCGCCAAGAGGCTGAGAGGCTGAGGAGCAGACCCTGCATGCAGCAAACTTCTTCCAGAGTGCCGCAAAAAGACAACAGCTTCAGACCGGGATCAGGGCATGTACCCTCCAACTTGGCATCCAGACCTGGGAATCCACAAGAAGACAAAAGTAGTTTAAGAGACCCCGCATGGCAGTACTCAAATCCCGGATACCAAGAGTTGACGGCTGTGGTCACCGAGGTGACTGCCCCAAATCAGGACGGTCCAGCAGATATCTCAGGCTGTGGTGATCTGGTGTGGGTTGAAAATCCTGAGGTGCATCGTAAAGCTGATAGTATTGCTGGTAAATATGGTGTGTGGATGCAAGATCCAGAAGCCAAGGAACCTTATGGTCCAGACATGGTATGGCGTATTGATTCTGTCGGTTCTGAAGTGCGTCAACTCTTCGGATATGAAAACATGGACCAGCTGACACGTGGCTTTCCCACCAAGGTTCTACTCCTGCCAGAATCTGTAGAGAGCACAGGTGCTACCATGTATAAAGGCTCCTTATACTACCAGCGGAGGCTCAGCCGCACCCTAATAAGATACGACCTACATGCTGAGAGCATTGCTGCTCGTCGTGATCTACCCCATGCTGGTTTCCATGGTCAGTTCCCCTACTCATGGGGTGGCTACACAGACATTGACTTGGCAATAGATGAAAATGGCTTATGGGCTATATACAGCACAAATAAAGCCAAGGGTGCTATCGTGATCTCCCAGCTGGACCCTCACAACCTTGAGGTGAAGGGTACCTGGGAAACAAAAATCCGCAAGACATCTGTGGCTAACGCTTTTATGATCTGTGGCAAGCTCTACACAGTTGCTAGTTACACCTCACCAAACACCACGGTTAATTACATGTTTGACACTGCAACCAGCCAGGGTAAAGCAATATCAGTGCCCTTCAAAAACCGTTATCGCTACAACAGCATGGTAGACTACAACTCCGCAAAAAGAAAGCTGTATGCTTGGGATAATTATTACATGGTGTCTTACAGTGTGAGACTTGGCAAGCAGgagtaaacattgtaaatttccATATCATCAaagcttgcattttttttttttacttaaaacatcCAGTAGGACGTCAATTGTTGGACTTACTGATTTTCAAAGACaatgaacttttttttctgaaaaaagaaCTGGATAAGTCAACCAATCAGGCTTTTGCTGGTATTTGTATAGgaaactgagtgtgtgtgtgtgtataccaaATAAAACACTTTCCTGGTAACATAAAAACAGAGTTTTTTCAAGATTTTCCcattatatacagtaaataccTTACAATTAACTGCATTGTATATCCTTCTCGATCAtagatttatctttgataaaAAAAGATGTTGACCAACAAGTTCCAAAATGGATAATGTATCAAATCATGTCGATATTCACATCCTTAATAATTTTATCCACTTAACATGTTAATAGAGAAATTATTTTTCTACCTATGTAAGTAATGTCTTGTCTGTTTTTGTGTATATGGCACTGAATAAATTCAAGGAAGGGGGAAAATATACTAGCAAACAACTGATTACAGCAAGCCTGCTTCTTAATTCATATATCATTGAGCAGTACGCAACTTTACGAACCTAAACCTTTGCTTGTTGTGTTTGTGCTCTAATACTTTATCATATAATCTTCACTCTGTATATGATGATCATTTTCCCTTCTCTCTTTTGAATTTGCTGCAAATCTCACATGCTGCTTGAGATGTTAAGATTGGGATTTTGTGGCTTTGGAAGCGTATTAActtgaaaataaagatttataaagTCTGCC

Function

symbol description
myoc Predicted to act upstream of or within positive regulation of cell migration; regulation of cell-matrix adhesion; and regulation of stress fiber assembly. Predicted to be located in several cellular components, including extracellular space; mitochondrial outer membrane; and rough endoplasmic reticulum. Is expressed in caudal fin skeleton; eye; and postcranial axial skeleton. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin).

GO:

id name namespace
GO:0051492 regulation of stress fiber assembly biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0001952 regulation of cell-matrix adhesion biological_process
GO:0005615 extracellular space cellular_component

KEGG:

id description
ko04812 Cytoskeleton proteins

ZFIN:

id description
ZDB-GENE-050425-2 Predicted to act upstream of or within positive regulation of cell migration; regulation of cell-matrix adhesion; and regulation of stress fiber assembly. Predicted to be located in several cellular components, including extracellular space; mitochondrial outer membrane; and rough endoplasmic reticulum. Is expressed in caudal fin skeleton; eye; and postcranial axial skeleton. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin).

Ensembl:

ensembl_id ENSDARG00000021789

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034275 True 2495 mRNA 0.44 4 15015557 15021628

Neighbor

gene id symbol gene type direction distance location
XLOC_017205 vamp4 coding upstream 9220 14968031 ~ 15006337 (+)
XLOC_017206 FP074855.1 coding upstream 16485 14998956 ~ 14999072 (+)
XLOC_017204 itpa coding upstream 66114 14941264 ~ 14949443 (+)
XLOC_017203 mir214a coding upstream 137819 14877639 ~ 14877738 (+)
XLOC_017202 mir199-3a coding upstream 140011 14875460 ~ 14875546 (+)
XLOC_017208 NA coding downstream 34368 15055996 ~ 15058705 (+)
XLOC_017209 NA coding downstream 90108 15111736 ~ 15114901 (+)
XLOC_017210 prdx6 coding downstream 142854 15164482 ~ 15184869 (+)
XLOC_017211 NA coding downstream 263636 15285264 ~ 15286146 (+)
XLOC_017212 NA coding downstream 507343 15528971 ~ 15529445 (+)
XLOC_017199 BX901920.1 non-coding upstream 354125 14657141 ~ 14661432 (+)
XLOC_017198 NA non-coding upstream 391639 14487757 ~ 14623918 (+)
XLOC_017217 NA non-coding downstream 859014 15880642 ~ 15895650 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000051_03147600_03152676 MYOC coding CI01000051 null 3147234 ~ 3153094 (+)