XLOC_018302 (hey2)


Basic Information

Item Value
gene id XLOC_018302
gene name hey2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 39588897 ~ 39596338 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00036034
GGAATGAAGTTTGAGACCTCCATTCGACGGCTCGGGGcgtgttttctattttttttttacggtgGGTGTTCCCGAAGCAGGACGTGGGCGTGAATGTGAGACTGAGGCTCCAGCGGTTCGTGGGAAAGGCGCTCAGAGAGTTTTTGGTGTCTGTACCTGCGCGCACTGCATCATGAAGCGGCCCTGTGAGGACAGCACGTCCGACAGCGACATGGATGAAACCATTGATGTGGGCAGCGAGAATAACTACTCTGGCCAAAGCAATGGTTCATTTATAAGATGTGGCTCACCTACAACGACATCCCAAGTCATGGCCAGAAAGAAGCGGAGAGGgATCATTGAAAAAAGAAGAAGGGACCGGATAAATAATAGCTTATCAGAGTTGCGTCGTCTGGTGCCAACAGCTTTTGAGAAACAGGGATCTGCCAAGTTGGAGAAAGCGGAAATATTGCAGATGACAGTGGATCATCTGAAGATGCTTCAGGCCACAGGAGGAAAAGGATATTTCGACGCTCATTCTCTGGCCATGGACTTCTTGAGCATCGGCTTCCGGGAGTGTCTGACTGAAGTGGCCAGGTATTTGAGCTCTGTGGAAGGCCTGGACTCCAGCGACCCTCTCCGTGTCCGTCTGGTTTCTCACCTCAGCAGCTGTGCCTCGCAGAGGGAAGCAGCCGCCATGACCACATCCATAGCCCATCACCAGCAGGCCCTTCACCCGCACCACTGGGCTGCCGCTTTGCATCCCATTCCTGCTGCGTTCCTGCAGCAGAGCGGACTTCCCTCCTCAGAGAGCTCCTCCGGCAGGCTGTCTGAGGCTCCTCAAAGAGGTGCAGCCCTTTTCTCCCATAGTGACTCGGCACTCAGAGCGCCCTCTACTGGAAGTGTGGCTCCTTGCGTGCCACCGCTGTCCACTTCTCTGCTTTCGTTATCAGCGACCGTTCACGCAGCAGCTGCTGCAGCTGCAGCTCAAACCTTCCCTCTATCATTTCCCGCTGGATTCCCACTCTTCAGCCCCAGCGTTACAGCATCTTCAGTGGCTTCTTCCACCGTGAGCTCTTCCGTTTCCACATCCACCACATCCCAACAGAGCAGCGGGAGCAGCAGTAAACCATACCGACCGTGGGGAACTGAAGTGGGAGCGTTTTAAATGTTGGATTTAAATGTTGGACGTCTTCCATGCTTTGTACATAAAGGAAAGCAGCGGCTATTGTGCCTGCTTCGGTCAGCAGCATGGGCTTTTGTCTTCCTCTACACTTGTGCACATATGCAGCGTCAAACTTAAGCCAACATTCTGGGAAGAAAAGAAAGAGTTTTTACACGTCGCACTGTGTTGGAAACCGTAAAGgaagtttgtttctgttttaacAGTGCCTGCATAAACACTGCTAACATGCTGCATTTGAGATGTATGCTTTGATATCATCTGACTTCCACAAACACCCAACAGCAGCTTTAGAGTGAACAGCTTGTTCTGAAACAAACCAAAGTTTTGCAGATAATCACTAAAGTgaggtgtttgtttttttatctctGATTTAACAATCCAGTTTGTAAATCTGTACATGTGTAAGATTGTAACTAGAGTTTATATTGAAATTAGTTCATTGGTATGATGCACTTCAATCACTACTGTTTGTTTGGGGGGAGACAGGATCTTCTCCGATTTATACAATAGGCCTACtgaagttgtttttttaaaataacattcacTAATACTCATGTGAGATTTTTCTACTACTGTAACTGTGTTAATAACCACCCTCTGTAAGATGTAACCTTTTCctatgcaaaaaaacaaatgtcCCTCAAGAACGAA

Function

symbol description
hey2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on cardiac muscle cell proliferation. Acts upstream of or within circulatory system development and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; cardiovascular system; hematopoietic system; mesoderm; and nervous system. Orthologous to human HEY2 (hes related family bHLH transcription factor with YRPW motif 2).

GO:

id name namespace
GO:0060853 Notch signaling pathway involved in arterial endothelial cell fate commitment biological_process
GO:0072359 circulatory system development biological_process
GO:0007219 Notch signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0048514 blood vessel morphogenesis biological_process
GO:0007275 multicellular organism development biological_process
GO:0048844 artery morphogenesis biological_process
GO:0001568 blood vessel development biological_process
GO:0001570 vasculogenesis biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0035912 dorsal aorta morphogenesis biological_process
GO:0045892 negative regulation of transcription, DNA-templated biological_process
GO:0050767 regulation of neurogenesis biological_process
GO:0060840 artery development biological_process
GO:0005634 nucleus cellular_component
GO:0005515 protein binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-000526-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on cardiac muscle cell proliferation. Acts upstream of or within circulatory system development and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; cardiovascular system; hematopoietic system; mesoderm; and nervous system. Orthologous to human HEY2 (hes related family bHLH transcription factor with YRPW motif 2).

Ensembl:

ensembl_id ENSDARG00000013441

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00036034 True 1816 mRNA 0.48 5 39588897 39596338

Neighbor

gene id symbol gene type direction distance location
XLOC_018301 pex7 coding downstream 6581 39520628 ~ 39582316 (-)
XLOC_018300 SLC35D3 coding downstream 71733 39513435 ~ 39517164 (-)
XLOC_018296 NA coding downstream 85930 39375883 ~ 39502967 (-)
XLOC_018303 BX936317.1 coding upstream 5518 39601856 ~ 39686127 (-)
XLOC_018304 tpd52l1 coding upstream 95455 39691793 ~ 39735987 (-)
XLOC_018305 NA coding upstream 147857 39744195 ~ 39746437 (-)
XLOC_018306 rnf217 coding upstream 153110 39749448 ~ 39789846 (-)
XLOC_018307 nkain2 coding upstream 210032 39806370 ~ 40119872 (-)
XLOC_017928 CU539064.1 misc downstream 29535196 10053405 ~ 10053701 (-)
XLOC_018299 NA non-coding downstream 174639 39410844 ~ 39414258 (-)
XLOC_018298 NA non-coding downstream 183928 39404209 ~ 39404969 (-)
XLOC_018289 BX569784.1 non-coding downstream 555961 39032821 ~ 39032936 (-)
XLOC_018288 dre-mir-124-2 non-coding downstream 683284 38905531 ~ 38905613 (-)
XLOC_018308 CR847530.1 non-coding upstream 322894 39919232 ~ 39920174 (-)
XLOC_018309 NA non-coding upstream 619031 40215369 ~ 40254485 (-)
XLOC_018311 NA non-coding upstream 733768 40330106 ~ 40336899 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000029_02145528_02148347 HEY2 coding CI01000029 null 2144450 ~ 2149108 (-)