XLOC_018475 (dusp10)


Basic Information

Item Value
gene id XLOC_018475
gene name dusp10
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 51917506 ~ 51946052 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00036287
aagagGCTCATCAGGCCGGTCGAGGGCTACTAATCCACTGTCAGGCTGGTGTGTCTCGCTCCGCCACCATCGTCATCGCCTACCTGATGAAACACACCTGGATGACCATGACGGACGCCTACAAGTTCGTGAAGTCGCGGAGGCCCATCATTTCGCCAAACCTCAACTTCATGGGGCAACTTTTAGAGTTCGAGGAAGACCTGAACAACGGCATCACTCCTCGAATACTGACGCCCAGACTCACAGGCCTCGAGACCCTCGTATAG
>TCONS_00036288
GCGCGTTCACATTCGTCCCCGTCTCTTTAATCCGGTTTCAGCGAACTGTCCTCTGATTGGCTCTCAATGACATCACCCTGCACTTCCTGCTCTCCGCCCATCTTGGCTCCGCCGCTGCTCTCCAGTGCGGTGCTCCATTGGCTCAAACTCCCGTCAGTCTGAAGTGATACTAGTGCAGACCCGCTACAAACTCCAAATACAGCCCAGAACACACAGCAAAGCAGGACGGGAGGAAAATGTTGCGGTTCTCCAGCGCCGGGACCGGCTGAACGGCTCAGACTGATCAATAACTGAAACTGCGGAGGAAAACACGgctgaaacacacacatttaacTGCTCGTCAGGACGTCTGAGTTCTCCGTGCTGTGCCAGCCCTCTGTGGTCTCTCCATGCCTCCGTCTCCTCTAGACGACAGAATTGTGGTGGCGCTGCCAAGGCCTATCCGACCTCAGGAACTCCGACTTCGCCTGGACACCAGCTACCTGGAAACCACCGTCGGCAAGACCACGGTAATCAGCAGCACCACCGTGGTGAAAATCCAGGCCGCCACGCTTTCGTATATGCCCTCGTCCAGCGGCTCCACACGCTCGCTGACGTGTGGATGCAGCAGTGCCAGCTGTTGCACCGTGACCACCTATGAAAAAGACGGCCAGGTCAGCGCCAGCAGCCCCAATTTACACTCTGGATCGGGATATGGCGTCCAGCAGGGGAGTGTGCACGGCAGTGCACCCAGCCTCACCTCCAGCCTGACCCGGGGCGGCATGCGGGTCATCCACCCTAATGAGCTGGCTAAAAAGCTGACGCATTGTCCATTAGGTCACCCGATCGGTCCGGTTCCCGTTATTATCGATTGTCGGCCGTTTTTGGAGTTCAATAAGAGCCACATTAGGGGTGCGATGCATATTAACTGCTCTGACAAGATCAGCCGCCGGCGCCTCCAGCAGGGTAAAATCACCGTCCTGGACCTGATCTCCTGCCGGCAGAGCAAGGACTCGTTTAAAGGGATTTTTTCTAAAGAGCTGGTGGTGTATGATGAGAGCACAGTGGACCCGGGACGGTTGACACCGTCTCAGCCGCTGCATGTGGTTTTGGAGTCACTACGTAGGGAAGGAAAAGACCCCATCGTTCTGAAAGGAGGTCTCTCTGGTTTCCGGCAGACCCACGCTGACCTGTGTGAGCACTCTCTCCATCTGGATGAGGGTCAGGACGGCAGCGGAGCCATGGGTTTGTCCGGGGCTCTACCTCATTCCCTGCCCTCCACGCCGGACATCGAGAACGCGGAGCTGACGGCCGTCCTGCCCTTCCTCTACTTGGGCAACGAGCGGGACGCGCAAGACCTGGAGCTTCTACAGCGTCTGGACATCGGTTTCGTCCTCAACGTCACCACACACCTGCCGCTCTACCACTACGACATCGCACGGTTCTGCTATAAACGTCTGCCCGCCACCGACAGCAACAAGCAGAACCTGCGGCAGTACTTCGAGGAGGCCTTCGAGTTCATAGaagagGCTCATCAGGCCGGTCGAGGGCTACTAATCCACTGTCAGGCTGGTGTGTCTCGCTCCGCCACCATCGTCATCGCCTACCTGATGAAACACACCTGGATGACCATGACGGACGCCTACAAGTTCGTGAAGTCGCGGAGGCCCATCATTTCGCCAAACCTCAACTTCATGGGGCAACTTTTAGAGTTCGAGGAAGACCTGAACAACGGCATCACTCCTCGAATACTGACGCCCAGACTCACAGGCCTCGAGACCCTCGTATAG

Function

symbol description
dusp10 Predicted to enable MAP kinase tyrosine/serine/threonine phosphatase activity; mitogen-activated protein kinase binding activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in negative regulation of JUN kinase activity; peptidyl-threonine dephosphorylation; and peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human DUSP10 (dual specificity phosphatase 10).

GO:

id name namespace
GO:0046329 negative regulation of JNK cascade biological_process
GO:0035335 peptidyl-tyrosine dephosphorylation biological_process
GO:0006470 protein dephosphorylation biological_process
GO:0000188 inactivation of MAPK activity biological_process
GO:0035970 peptidyl-threonine dephosphorylation biological_process
GO:0016311 dephosphorylation biological_process
GO:0043508 negative regulation of JUN kinase activity biological_process
GO:0005737 cytoplasm cellular_component
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity molecular_function
GO:0008138 protein tyrosine/serine/threonine phosphatase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016791 phosphatase activity molecular_function
GO:0051019 mitogen-activated protein kinase binding molecular_function
GO:0008330 protein tyrosine/threonine phosphatase activity molecular_function
GO:0004721 phosphoprotein phosphatase activity molecular_function
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG:

id description
ko04010 MAPK signaling pathway
ko04013 MAPK signaling pathway - fly
ko04214 Apoptosis - fly
ko01009 Protein phosphatases and associated proteins

ZFIN:

id description
ZDB-GENE-041014-271 Predicted to enable MAP kinase tyrosine/serine/threonine phosphatase activity; mitogen-activated protein kinase binding activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in negative regulation of JUN kinase activity; peptidyl-threonine dephosphorylation; and peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human DUSP10 (dual specificity phosphatase 10).

Ensembl:

ensembl_id ENSDARG00000052465

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00036287 False 266 mRNA 0.55 1 51917506 51917771
TCONS_00036288 True 1769 mRNA 0.57 4 51917506 51946052

Neighbor

gene id symbol gene type direction distance location
XLOC_018474 NA coding downstream 3233 51910775 ~ 51914273 (-)
XLOC_018473 mia3 coding downstream 85690 51758426 ~ 51831816 (-)
XLOC_018472 BX936461.1 coding downstream 168338 51748497 ~ 51749168 (-)
XLOC_018471 brox coding downstream 189646 51700633 ~ 51727860 (-)
XLOC_018470 si:ch211-14a11.2 coding downstream 220069 51695479 ~ 51697437 (-)
XLOC_018476 CU905509.1 coding upstream 198139 52144191 ~ 52144305 (-)
XLOC_018477 hlx1 coding upstream 249473 52195525 ~ 52199311 (-)
XLOC_018478 rhpn1 coding upstream 287929 52233981 ~ 52271262 (-)
XLOC_018479 naprt coding upstream 327394 52273446 ~ 52314299 (-)
XLOC_018480 si:ch1073-287p18.1 coding upstream 386920 52332972 ~ 52338810 (-)
XLOC_017928 CU539064.1 misc downstream 41863805 10053405 ~ 10053701 (-)
XLOC_018467 NA non-coding downstream 275158 51619897 ~ 51642348 (-)
XLOC_018462 CU660013.2 non-coding downstream 574773 51342164 ~ 51342733 (-)
XLOC_018461 CU660013.3 non-coding downstream 575989 51341381 ~ 51341517 (-)
XLOC_018481 NA non-coding upstream 595414 52541466 ~ 52544754 (-)
XLOC_018486 NA non-coding upstream 707448 52653500 ~ 52654969 (-)
XLOC_018488 NA non-coding upstream 727056 52673108 ~ 52676467 (-)
XLOC_018489 BX005301.1 non-coding upstream 740177 52686229 ~ 52691004 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000029_07672445_07687240 DUSP10 coding CI01000029 null 7672445 ~ 7687873 (+)