XLOC_018497 (gata4)


Basic Information

Item Value
gene id XLOC_018497
gene name gata4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 52952116 ~ 52967878 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00036318
GGGTAAAGGTCATCCCGGTAAGCTCCGGTTCCCGACAGCCGCTCGTGGAGCAATAATCGCTCACCTGTGGATATGTATCAAGGTGTAACGATGGCCGCCAACCACGGAGCTGCGTCTTACGAGTCCGGTTTCCTCCATAACTCGACTTCTCCGGTGTACGTGACACCCACACGGGTGACTCCGATGATCCAGGCCCTCCCGTACCTACAGGCGCCCCAGCAGAGCAGCCCGGCGTCTGGACACTCTGGATGGGCACAGCCGGGCGTGGAAACCACCTCCTATAACTCAAGCACCGGGCACCATCATTCTCCGGTGTCCAGATTCACTTTCTCCACCAGTCCTCCGTTAACTTCAGGCCGGGATACCGCAACTTATACAAGCCGGGAGCATTTCGGGTCTCGGGCTCTTAGCGGCTCTTATCACAGCGGTTACCCGGCCTATGTGAGCCCTAATATCGGAGCCTCTTGGACGGCTTCGCACTTCGACAGCTCCGTACTGCACAGCCTCCAGACCGGAGGAGCGGCCGCTGCTAGACACCCCAATTTAGAGTTTTTTGATGATCTGGGCGAGGGCCGGGAGTGTGTGAACTGCGGGGCGATGTCGACTCCTCTGTGGCGGCGGGACGGCACCGGTCATTACCTGTGCAATGCCTGTGGACTCTACCATAAGATGAACGGCATCAACCGGCCGCTGGTCAAACCACAGAGACGACTGTCTGCGTCCAGGCGGGTGGGTTTATCCTGCACAAACTGTCAGACTACCACAACAACTCTTTGGAGACGCAATGCAGAAGGAGAGCCAGTCTGCAACGCCTGTGGACTCTACATGAAGCTCCACGGGGTTCCTCGTCCTCTCGCCATGAAGAAAGAGGGCATTCAGACACGAAAGCGCAAACCCaaaaacatcagcaaaaccaaacCCGGCTCCTCTGAAGGTCAGTCGGCGATCAGCGCTGTGAACTCCAGTCCAACAGAAGAGACGCGACCCATCAAGACTGAACCAGACACAACACCGCTCTACACACaccacaacatacacacacagGTATCTGCGTTTCCAGCATATATGGGCTCTCCAAGCGGATCCTCCAGCACCAAGAGTGAAGTGTGGAACAGCCTGATTCTGgcataaacgcacacacacacacacacacacacacacacacacacacatgcacacacacacacacacacacacatacacacatacccaCA

Function

symbol description
gata4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within animal organ development; cardiac muscle tissue regeneration; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including endocrine system; gut; liver and biliary system; mesoderm; and pericardial region. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4).

GO:

id name namespace
GO:0030099 myeloid cell differentiation biological_process
GO:0007507 heart development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0048797 swim bladder formation biological_process
GO:0055010 ventricular cardiac muscle tissue morphogenesis biological_process
GO:0045165 cell fate commitment biological_process
GO:0035050 embryonic heart tube development biological_process
GO:0060975 cardioblast migration to the midline involved in heart field formation biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0061026 cardiac muscle tissue regeneration biological_process
GO:0001889 liver development biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0001947 heart looping biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko04022 cGMP-PKG signaling pathway
ko04218 Cellular senescence
ko04530 Tight junction
ko04919 Thyroid hormone signaling pathway
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-980526-476 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within animal organ development; cardiac muscle tissue regeneration; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including endocrine system; gut; liver and biliary system; mesoderm; and pericardial region. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4).

Ensembl:

ensembl_id ENSDARG00000098952

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00036318 True 1214 mRNA 0.56 6 52952116 52967878

Neighbor

gene id symbol gene type direction distance location
XLOC_018496 fdft1 coding downstream 12615 52907397 ~ 52939501 (-)
XLOC_018495 ctsbb coding downstream 49396 52886927 ~ 52902720 (-)
XLOC_018494 dspb coding downstream 69235 52851793 ~ 52882881 (-)
XLOC_018492 tbc1d7 coding downstream 105904 52825215 ~ 52846212 (-)
XLOC_018493 CABZ01076171.1 coding downstream 124990 52827010 ~ 52827126 (-)
XLOC_018498 NA coding upstream 5982 52973860 ~ 52995339 (-)
XLOC_018499 CABZ01066813.1 coding upstream 101843 53069721 ~ 53078607 (-)
XLOC_018500 CABZ01115113.1 coding upstream 202091 53169969 ~ 53176675 (-)
XLOC_018501 NA coding upstream 319995 53287873 ~ 53292515 (-)
XLOC_018502 wasf1 coding upstream 332710 53300588 ~ 53366137 (-)
XLOC_017928 CU539064.1 misc downstream 42898415 10053405 ~ 10053701 (-)
XLOC_018491 NA non-coding downstream 132500 52818807 ~ 52819616 (-)
XLOC_018489 BX005301.1 non-coding downstream 261112 52686229 ~ 52691004 (-)
XLOC_018488 NA non-coding downstream 275649 52673108 ~ 52676467 (-)
XLOC_018486 NA non-coding downstream 297147 52653500 ~ 52654969 (-)
XLOC_018505 NA non-coding upstream 836484 53804362 ~ 53810669 (-)
XLOC_018510 NA non-coding upstream 1078300 54046178 ~ 54046733 (-)
XLOC_018511 NA non-coding upstream 1082554 54050432 ~ 54051494 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000029_08250264_08262665 GATA4 coding CI01000029 null 8250249 ~ 8262665 (-)