XLOC_022627 (pfkfb2a)


Basic Information

Item Value
gene id XLOC_022627
gene name pfkfb2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 42765700 ~ 42810664 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00044557
AGACACAAACACTTCCTGAAACACGGAGAGCACTTCAAAATCTCCTCTACtccatttaaaatcattttaaaccgaGTGTGAATGGGAAACGACCCGCGTGTTTGTGCTCTCTCAGGTGCAGGACTGACCTATGACCTCTGCTGACCTCTTCTGACCCCTCACAACTTTGTCAGTCTGCATGTGAAAGATAATGGACAGTTCGAATGAGCACAAGAAGACGGAGCCCAGAGTCACTGAGAAGAAATGCTCATGGGCCTCACACATGACAAACTCACCCACAGTGATAGTGTTGGTTGGTCTTCCTGCCAGAGGAAAGACGTATATCTCCAAGAAGCTGACGCGATACCTTAACTGGATCGGTGTTCCTACTAAAGtttttaaCCTGGGTGTTTATAGAAGAGAAGCTGTGCAGTCCTACAAGTCCTATGACTTCTTCCGTCACGACAATGAAGAGGCCATGAAGATCAGGAGACAGTGCGCCATTGTGGCTCTTCAGGACGTGAAGTCTTATCTGAACGAGGAGGGAGGCCAGATCGCTGTTTTTGATGCTACAAACACAACCAGAGAGAGACGAGACCTCATCTTGAGTTTTGCGCAGGATCACTCCTATAAGgTGTTTTTTGTCGAGTCTCTTTGTAGCGACCCAGAAGTCATTGCTGCCAATATAATGGATGTGAAGGTTTCCAGTCCGGATTATCCGGAGCGAGACAGAGAGAGCGTAATGGAGGACTTCCTCAAGAGAATCGAGTGCTACAAAGTCACATATCAGCCCTTAGACCCCGATGAACATGACAAGGCGCTGTCCTTCATCCAGGTGATCAACGTGGGTCAGCGTTTCCTGGTGAACCGCGTTCAGGATTATATTCAGAGTAAGATCGTCTACTACCTCATGAACATCCACGTTCAGAAACACTCCATCTACCTCTGCCGACACGGAGAGAGTCAGCACAACGTCCAGGGCTGCATCGGTGGAGACTCGGAGCTCTCCAGCAGAGGAAAAGAGTTCTCTAAAGCCCTGCGTGGGTTTCTGGAAACCCAGAAGATCCCAGACCTGAAGGTCTGGACCAGCCAGCTTAGACGCACGATTCAGACGGCGGAAGAGCTGGGCGTCCCGTACGAACAGTGGAAAATCCTCAACGAGATCGACGCTGGCATCTGTGAAGAAATGACGTATGAGAAGATTAAAGAAGCATACCCGGATGAATATTCTCTCAGAGACCAGGACAAATATCATTACAGATACCCAGGAGGAGAGTCGTATCAGGATCTGGTCCAGCGTCTGGAGCCGGTCATCATGGAGCTGGAGAGACAAGGAAACGTGCTGGTGATCTGCCATCAGGCTGTCATGCGCTGCCTGCTCGCATACTTCCTGGACAAGAGTGCCAatGATCTGCCGTATCTGAAGTGTCCTCTCCATGCGGTGCTCAAACTCACCCCTGTGGCTTATGgcTGTAAAGTGGACATGTTTGACCTGAAAGTAGAAGCTGTAAACACACACCGGGACAGACCTCTTGGCAGGGGCAGACAGGTAGTGGCTCCGGCCTTGCTGAGAAGGAACAGTTTCACTCCTCTGTCCAGTCAGGATCAGGTGAAGCGGCCGAGGCTCTTCAGCGTGGGAAACCCGCCGCGGATAACAAGCGCACCTGCTTTATCAACAACACGATTCCCACAGACACGGGAGAGCGAAGAGCTGAGCGAGAGCCAGGAGTTACTGAACTGCTTCAGCCCATCAGACTCAAAAGAGGTCATCCAAGAGTGAcgacacaaacaaaaacacaacttaCACAAGTGACGCCCATCAGAAATTAAACCGGTTTCCTCCAGACATGACTCAACTCTCTCTCCGTCCGCCCTTCAATCTTCATCCGTCCACAAAATGCTGGAAAATACGGTAAAACCATGCCAGGCACATGTGAGTTATTCAATATACACTCCATTAATCTGCTGATTGACAGCCTGTGCAACCAATAAGGGCCAAttaagtgggtgtggcttgttccGGTTAATCTGATTGGCCCTCCAGAATCTTGAAAAGCACTGCTATtgattaatgtgacttttttgttttcataatagCCAAATTTGACTGGATATAAGTGTAAATATGTGTTTTATTCTATCAGTTATTCATCTGTAAtgctatttttatgtttatagaCTTAATGTTGCGCTCTTGAATGTTTTATCGAATATAACGAATGTGAAATGAAGAAGTTATAAAAGTTATGTTCTGCTGTTTTATGTTCAGACTGGAGTATCAGGGTAAAAAGCCTATAAGTTGATTGTTTAAGCTGTTGTAAATGAGTGTGACCTTTAATATTCTTCTTTAAAACAAAACGCACGCTCTGAAGCATTAATTATAGAGCTTTATTAACGTCTTTAATTGCGTTACGGATGatctacactttaaaaataatatctgTTAGTGAACAGTTTCCGTATATTGTGATTCACAAAAGGTATTTATGTTTATGAATTGCTTCATGGGATGAaatgttgtcacgatactggaatttgataccaattGGTACTGAGATTTTAAAagtgtccatttcccgctaacactTGAGCGCTGTTGAGCTCATTCTTAAAcggcgctgatttgccattgtgttcacatgctcaacagaaaggactgtgattggccgtgaaggtcttcagttcaccaaactcactgctaTTTATTGAGTGtaactacagatacagggacactggagcgttttaaagccacgaagatcagctgatctgtctatgagctgacattagagcgatccgctgatgaatcgactgatatttgcagctttaaaacactccagtgtccgtATATCTGTGCTTACACTCAGTGAGTGTGTccaatgttagcaggaaatggacgtgtTTAAAATTTTACTATCGATTGGTACTGACAAACACTCTAGTGGGatattgatctctgctctgttgacttttgatgtagaaaatttaactctacagtgacttttattgacattttagtagtttcaaATAATAATGCAATGTATAAGGTATAATATAGAGCGAAATAAgtctgttaaataacagaaaatgcactggcagtttattgcaaggtgtttgtagcgtaatatacaacaccaacccagacaatatagcacttaaAACTATGAAAAGTGTTCATAAAGTCACTTTTTAAGGATGAAAGATGATGTGAAGAAAATAAAAGTCTCATactgcaattcaaaagcagaaataaacttggaaaaataaaaacgtgaatcacaaaatatggaaaactgcatatttacggattttttaagtgtttaagtaCACTTAAAACTACTGAGAACATCGCAACTCCTACTTTACTGTATTACTTTTCACATTTTAGCGTCTGTTAATAGTTATGAAAAGCTATTTAtaaggacttttattttgcatcAGATCTAGTAGGATGTTTTTAAATGGTGTTGTAAATGGTTTCATGAATATAAATGTATGTTCTTGTTGTCTGAATTTTGCATTACAAGTTTTTTGGATGCACAGAGTATGTTGTTTAAGTGTTTAATACTCTTAAAGGGACTCAGAATTAA

Function

symbol description
pfkfb2a Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to act upstream of or within fructose metabolic process and phosphorylation. Predicted to be active in cytosol. Orthologous to human PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2).

GO:

id name namespace
GO:0016310 phosphorylation biological_process
GO:0006000 fructose metabolic process biological_process
GO:0006003 fructose 2,6-bisphosphate metabolic process biological_process
GO:0005829 cytosol cellular_component
GO:0003873 6-phosphofructo-2-kinase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-966 Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to act upstream of or within fructose metabolic process and phosphorylation. Predicted to be active in cytosol. Orthologous to human PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2).

Ensembl:

ensembl_id ENSDARG00000023840

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00044557 True 3566 mRNA 0.42 16 42765700 42810664

Neighbor

gene id symbol gene type direction distance location
XLOC_022626 si:ch73-217n20.1 coding downstream 13150 42726161 ~ 42752550 (-)
XLOC_022625 NA coding downstream 138258 42622345 ~ 42627442 (-)
XLOC_022624 CT997819.3 coding downstream 250698 42508734 ~ 42515002 (-)
XLOC_022622 NA coding downstream 311161 42362045 ~ 42454539 (-)
XLOC_022623 CU013526.2 coding downstream 362020 42403564 ~ 42403680 (-)
XLOC_022628 NA coding upstream 17969 42828633 ~ 42831162 (-)
XLOC_022629 dlgap4a coding upstream 25461 42836125 ~ 42883522 (-)
XLOC_022630 CABZ01066224.1 coding upstream 73939 42884603 ~ 42906528 (-)
XLOC_022631 BX004770.1 coding upstream 210530 43021194 ~ 43125946 (-)
XLOC_022632 CR545469.1 coding upstream 433427 43244091 ~ 43289451 (-)
XLOC_022621 NA non-coding downstream 430709 42331919 ~ 42334991 (-)
XLOC_022637 CABZ01117597.1 non-coding upstream 719937 43530601 ~ 43530715 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00013707 pfkfb2,LOC108436129 coding CM030125.1 CM030125.1 39603101 ~ 39627214 (+)