XLOC_022636 (e2f1)


Basic Information

Item Value
gene id XLOC_022636
gene name e2f1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 43467799 ~ 43486714 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00044572
ATGTCTGAGGGTTTTATTTCGGGTCAGACCTCGGAGGACCTGCTGGCTGATTTCGAGTCTCTGTTGAACAATGGCAGTATTGATCTCAGCGAAGATCATCAAATTGTCATCATCTCCACTCCTGGCACGGCCACCACCAGCACTGCTACGGGTGACATTTTACTGTTCGCAACGCCACATCATACAAACCACCGGAGACCGATTTTGGGCCGCCCGCCGGTGAAAAGAAAGTTGGATTTAGACAGCGATCATCAGTACATTTGCACTTCTCGAACCGCTTCAAATGGACCCACACCTCCAGCCACACCCGCACCTCCCAGAGTGCCTAAGCTGGCTGTGGAGAAATCCCGCTACGACACGTCTCTGAATCTGACCACCAAACGCTTTCTGGATCTCCTGGCTCAGTCTCCGGACGGCGTGGTGGACCTGAACTGGGCCTCACAGGTGCTGGACGTCCAGAAGCGACGCATCTACGACATCACCAACGTCCTGGAGGGCATTCACTTAATCTCCAAGAAGTCCAAGAACAACATCCAGTGGCTAGGGAATCGTATCGACGGCGCATCTCTGGCCAGGTTTCAGGAGCTGCAGAAGGAGGTTTCTGAGCTGACGGAGGCCGAGGAGAAACTGGACGAACTCATTAATAAATGCAGTTTACAGCTACGGCTCCTCACTGAGGACACACACAACAAGAAATATCCTTTACCTGTTACGCTGGGATACGTCAGGTGTCAGGATCTGCGTAATACAGTCGATCCTCCAGATCAGATCATCATGGTGATTCGAGCTCCGGCAGAGACAGCCATGCAGGTGTCTGAACCCAGCGAGGGTTACCAGATTTCGCTGAAGAGCTCCAAAGGGCCAATCGATGTGTTCCTGTGTCCTGAAGATAGTTCTGGCGTTTGTAGTCCAGTCACTGACTGCAGTCCAGCTAAATCCTCCAATCAGAGTCCAGCAAAGTCTGACCCCGCCTCACAAGAAGTGACATCAACACCGACGACTCTGCCAAGCTCCTCCCCTCTGCCTCTGCACACAGACTCTGAATCGTTTCTGGACTCTGACCCGTTTTCTGGCATATGTGCGATGCCAGATTTCGATTTGTCTCCTTTGGACTCTGATTTCCTTCTGGAGCGGAGCGGGGCAGCAGACGGGCTCGGCCTCCCACTGGACAGCTTTATCTGCCTGTCTCCGCCGCACAGCCAGGACTATCACTTCGGCCTGGAGGATCATGAGGGCGTCAGTGAGCTGTTCGACTGCGACTTCAGTGACCTCGTCCCTCTGGAGTTCTGA

Function

symbol description
e2f1 Predicted to enable DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Acts upstream of with a positive effect on activation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; lung small cell carcinoma; lung squamous cell carcinoma; pancreatic adenocarcinoma; and pancreatic ductal adenocarcinoma. Orthologous to human E2F1 (E2F transcription factor 1).

GO:

id name namespace
GO:0048469 cell maturation biological_process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
ko04137 Mitophagy - animal
ko04110 Cell cycle
ko04218 Cellular senescence
ko05200 Pathways in cancer
ko05206 MicroRNAs in cancer
ko05207 Chemical carcinogenesis - receptor activation
ko05212 Pancreatic cancer
ko05225 Hepatocellular carcinoma
ko05226 Gastric cancer
ko05214 Glioma
ko05220 Chronic myeloid leukemia
ko05218 Melanoma
ko05219 Bladder cancer
ko05215 Prostate cancer
ko05224 Breast cancer
ko05222 Small cell lung cancer
ko05223 Non-small cell lung cancer
ko05166 Human T-cell leukemia virus 1 infection
ko05161 Hepatitis B
ko05160 Hepatitis C
ko05163 Human cytomegalovirus infection
ko05167 Kaposi sarcoma-associated herpesvirus infection
ko05169 Epstein-Barr virus infection
ko05165 Human papillomavirus infection
ko04934 Cushing syndrome
ko01522 Endocrine resistance
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-131024-3 Predicted to enable DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Acts upstream of with a positive effect on activation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; lung small cell carcinoma; lung squamous cell carcinoma; pancreatic adenocarcinoma; and pancreatic ductal adenocarcinoma. Orthologous to human E2F1 (E2F transcription factor 1).

Ensembl:

ensembl_id ENSDARG00000103868

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00044572 True 1290 mRNA 0.53 8 43467799 43486714

Neighbor

gene id symbol gene type direction distance location
XLOC_022635 rprd1b coding downstream 13276 43405205 ~ 43454523 (-)
XLOC_022634 zgc:174862 coding downstream 74210 43320903 ~ 43393589 (-)
XLOC_022633 si:rp71-80o10.4 coding downstream 160562 43300892 ~ 43307237 (-)
XLOC_022632 CR545469.1 coding downstream 178348 43244091 ~ 43289451 (-)
XLOC_022631 BX004770.1 coding downstream 341853 43021194 ~ 43125946 (-)
XLOC_022637 CABZ01117597.1 coding upstream 43887 43530601 ~ 43530715 (-)
XLOC_022638 itchb coding upstream 48510 43535224 ~ 43595956 (-)
XLOC_022639 CABZ01117603.1 coding upstream 111247 43597961 ~ 43609595 (-)
XLOC_022640 NA coding upstream 178698 43665412 ~ 43668843 (-)
XLOC_022641 abce1 coding upstream 208322 43695036 ~ 43718067 (-)
XLOC_022630 CABZ01066224.1 non-coding downstream 561271 42884603 ~ 42906528 (-)
XLOC_022628 NA non-coding downstream 636637 42828633 ~ 42831162 (-)
XLOC_022625 NA non-coding downstream 840357 42622345 ~ 42627442 (-)
XLOC_022642 NA non-coding upstream 397155 43883869 ~ 43884804 (-)
XLOC_022643 NA non-coding upstream 441784 43928498 ~ 43930231 (-)
XLOC_022644 NA non-coding upstream 502525 43989239 ~ 43992522 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000252_00084717_00089435 E2F1 coding CI01000252 null 84413 ~ 91160 (+)