XLOC_022638 (itchb)


Basic Information

Item Value
gene id XLOC_022638
gene name itchb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 43535224 ~ 43595956 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00044574
AAATGATGTTCTCACAGTCTGACAGGAAACGGACTTTGGCCTCAGTGGAAGGGCTGATCCAGAAAAAGCGTCTTTGATGACGTGTTGCGTGAAGATGGCGGAAGTTCATTCCTGATCTGAGCCGGAGTCTCTCGGTACGGATTCGGTAATAAAACTCTCCGAGGACTGATCGGTTTCGGCTTCACGACTCACATCCGACCCGCCGGCAAATTCGGgAGTCAGCGTAGCCGCATGTCATGGCCTGCAGTGTTGCTAAAGCAGCTCCTGCTAATGGCTTCCCAATGAAGGCTCAGCTGCAGATCATGGTGATTTCTGCCAAACTCAAGGAAAACAAGAAGAACTGGTTCGGTCCGAGTCCGTATGTGGAGGTGTGTGTGGATGGCCAGTCGAAGAAGACGGAGAAATGCAACAACACACACTCGCCCAAGTGGAAGCAGTCGTTCGCAGTGATCGTGACTCCATTCAGCAAGCTGATCTTCCGTGTTTGGAGCCACCAGACGCTCAAATCAGACCTTCTGCTGGGCGTGGCCACACTCGACATCAGCGAGAcgctcaagtcacatgacatgaaaATCTGTGAGGTGGTGCAGACGCTACAACTGTGCGACAGGGATCAGTCTGACAGCATCGGGGATCTGTCCGTGTGTCTGGACGGCCTGCAGGTGGATCCTGAAATGTTCCAGTCAGCTGAGGCCAGCAACCAGAGTCAGTCGCTCAATACTTTAAATGGGGAATCTGAGCTCAATGAAGACTCGGGCCGAAGcaGAGATCCATCTCCTTCAGTGTCAGAGGGTCAGGATCGTCCGGCGGCTCCTAACGGGCGAGTGAATGGCTTGGATTCTCCTTCAGTTTCTGCCAGAAGCTCTCGAGCTCAGAGACCTCCGCGGCCCTCGCGCCCTCCTCCACCCACCCCTCGCAGACCCACATCTTCTCCAGCTTCCTCTACCGGCTCATTTCCAGACGGCAGCGATTCGTCTCGTTCAGACACTCCAGTTCGGAATCCCACAGGGGGAGGAGCCTCTGATTCTAGCCCCGCCCCCACAGTGGAGCAGCCTGGTAGGACAGCCCTTAGTGTAGGCCCCACCCCCAGCAGGATCCCCAGCATGGTGAACGCTGGACCGCTGCCACCCGGttgggAGCAGCGTGTGGATCAGAATGGCCGTCTGTACTTTGTTGATCATGTGGAGAAGAGGACGACATGGGAGAGACCAGAGCCACTGCCGTCAGGCTGGGAGCGGCGCGTGGACCCGATGGGTCGGGTGTATTTCGTGGATCACATCACCAGAACTACCACATGGCAGCGGCCCACCATGGAGACGGTGCGCAACTATGAGCAGTGGCAGCACCAGCGCAGTCAGCTGCAGGGGGCAATGCAGCAGTTCAACCAGAGGTTCATCATCGGGCTCCAGGATCAGGCTTCAGCCACCCAGAATAAGGAGTTTGATCCGCTGGGTCCACTGCCGCACGGCTGGGAGAAGAGAACAGACTCCAATGGCAGAGTTTATTTTGTTCATCACCCGACCAGATCCACACAGTGGGAGGATCCGCGAACTCAAGGTCTGCTTAATGAGAAGCCTCTGCCTGAAGGATGGGAGATGAGGTTCACGGTCGATGGCATCCCTTACTTTGTAGATCACAACCGCAGAACCACTACTTATATCGACCCGCGCACTGGAAAATCCTCCCTtgagaacggTCCTCAGATCACATATGTACGAGACTTCAAAGCCAAAGTTCAGTACTTCAGATTCTGGTGTCAGCAATTATCGATGCCGCAGCACATAAAGATCAACGTCAGCCGCAAAACTCTCTTTGAGGACTCCTTCCAGCAGATCATGAGTTTTAGCGCTCAGGATCTGCGGCGCAGGCTCTGGATCATCTTTCCTGGAGAAGAAGGACTGGATTATGGAGGAGTGGCCAGAGAGTGGTTTTTCCTGCTGTCCCACGAGGTCCTGAACCCGATGTACTGCCTGTTTGAATACGCCGGGAAAGACAACTACTGTCTGCAGATAAACCCCGCCTCCTATATCAACCCCGACCACCTCAAATACTTCAAGTTCATTGGTCGCTTCATCGCCATGGCTTTGTTTCATGGGAAGTTCATCGACACAGGCTTTTCTCTGCCGTTCTACAAGCGCATCCTGAACAAGCCGCTGACTCTCAAAGACCTGGAGTCCATCGACCCGGAGTTTTACAACTCGCTCATCTGGATCAAGGATAATAACATCGAGGAGTGCGGCCTGGAGATGTTTTTCtcggtggataaggagattctgGGTGAAGTGTCGACTCACGAGCTGAAGCCGGACGGAGGAAACATTCAGGTCACCGAGGAGAATAAGGAGGAGTATATTAGgctggTGGCAGAGTGGCGTCTGTCTCGCGGTGTGGAGGAACAAACTCAAGCTTTCTTTGAGGGATTCAACGAGGTTCTTCCACAGCAGTACCTGCAGTATTTCGATGCCAAAGAACTGGAGgTGATGTTGTGTGGGATGCAGGAAATCGACCTGAACGACTGGCAGAGGAACACCATTTACAGACATTACACCTCCTCCAGTAAACAGATCATGTGGTTCTGGCAGTTCATTAAGGAGATGGACAATGAAAAGCGTATGAGACTCCTGCAGTTCGTCACAGGCACCTGCCGTCTGCCTGTCGGAGGATTCGCAGACCTCATGGGGAGCAATGGACCACAGAAGTTCTGCATCGAGAAGGTCGGCAAAGAGAACTGGCTTCCTCGGAGCCACACATGGTACATGACCTGACCATAAACATCATGTTCATCTCAGCATTataaaataggatttttttttttaatctgtggaCACATTTTCAAATTGCATtcataaaataactataataatagcTAAATATATACTATCTTTAACATTATTAGTAGCAAATATTAGTAGTAtataagtacacacacacacattggggaAAATAAGTATGCAATACACAATGTTTTCTCAGAAAACAgatatttctaaaggtgcagtCGACATGAAATTTTcatcagatgttgataacaaccaaataatccatatatgcaaagaaaactaatctaaatagtttacaaatgaaattctgtgtaataaaatgaaatgacgcagggaaaaagtattaaacGCATGAACaaagggaggtgtagttcagcagtgaaagcccagacagctggttcaacatctacattagcaggaggatgaagatgaaaccagggtggacgcAAGACAATCATCCAAAACACTGCCAAGGAGACTcttagatgctttcagagaaagaaaatcaagctgtagaatggcccagccaatcgcctgatctgaatccaatagagaatcctatgtatgtatatatatat

Function

symbol description
itchb Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within posterior lateral line neuromast primordium migration. Predicted to be active in cytoplasm. Is expressed in posterior lateral line primordium. Orthologous to human ITCH (itchy E3 ubiquitin protein ligase).

GO:

id name namespace
GO:0045732 positive regulation of protein catabolic process biological_process
GO:0035519 protein K29-linked ubiquitination biological_process
GO:0070534 protein K63-linked ubiquitination biological_process
GO:0016567 protein ubiquitination biological_process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0070936 protein K48-linked ubiquitination biological_process
GO:0048920 posterior lateral line neuromast primordium migration biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0061630 ubiquitin protein ligase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-131024-2 Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within posterior lateral line neuromast primordium migration. Predicted to be active in cytoplasm. Is expressed in posterior lateral line primordium. Orthologous to human ITCH (itchy E3 ubiquitin protein ligase).

Ensembl:

ensembl_id ENSDARG00000099199

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00044574 True 3358 mRNA 0.50 23 43535224 43595956

Neighbor

gene id symbol gene type direction distance location
XLOC_022637 CABZ01117597.1 coding downstream 4509 43530601 ~ 43530715 (-)
XLOC_022636 e2f1 coding downstream 48510 43467799 ~ 43486714 (-)
XLOC_022635 rprd1b coding downstream 80701 43405205 ~ 43454523 (-)
XLOC_022634 zgc:174862 coding downstream 141635 43320903 ~ 43393589 (-)
XLOC_022633 si:rp71-80o10.4 coding downstream 227987 43300892 ~ 43307237 (-)
XLOC_022639 CABZ01117603.1 coding upstream 2005 43597961 ~ 43609595 (-)
XLOC_022640 NA coding upstream 69456 43665412 ~ 43668843 (-)
XLOC_022641 abce1 coding upstream 99080 43695036 ~ 43718067 (-)
XLOC_022642 NA coding upstream 287913 43883869 ~ 43884804 (-)
XLOC_022643 NA coding upstream 332542 43928498 ~ 43930231 (-)
XLOC_022632 CR545469.1 non-coding downstream 245773 43244091 ~ 43289451 (-)
XLOC_022631 BX004770.1 non-coding downstream 409278 43021194 ~ 43125946 (-)
XLOC_022630 CABZ01066224.1 non-coding downstream 628696 42884603 ~ 42906528 (-)
XLOC_022628 NA non-coding downstream 704062 42828633 ~ 42831162 (-)
XLOC_022644 NA non-coding upstream 393283 43989239 ~ 43992522 (-)
XLOC_022645 CABZ01071875.1 non-coding upstream 414469 44010425 ~ 44010541 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000252_00046722_00065570 ITCHB, ITCH coding CI01000252 null 46558 ~ 65649 (+)
bowfin (Amia calva) AMCG00008324 LOC106566898 coding CM030123.1 CM030123.1 52388795 ~ 52425671 (-)