XLOC_028384 (mrap2b)



Basic Information


Item Value
gene id XLOC_028384
gene name mrap2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007115.7
NCBI id CM002888.2
chromosome length 78093715
location 905483 ~ 908821 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00055129
ATGAGTGAATATTCAAACCGCAGCCAAGCCGGAGCTGATTACGAGTGGCATTATGAATATTACGAGGACGAGGAGCCCGTGTCTTTTGAGGGACTGAGAGCAAACCGCTaCTCTATCGTGATTGGCTTCTGGGTCGGCCTCGCCGTCTTCGTCATCTTCATGTTCTTTGTGTTAACTCTGCTGACCAAAACAGGAGCTCCACATCCAGAGATGTGTGATGCCAGCATGAAGCCtcatgttctgattggctgtgagCTGGAAGTGGGCGGGTCTCTGGCATTTTCTCTGCCACCGCTGCCTGACCAATCACGTTCCCTCTTTCACTTCTACATCCATAAGGAGGAGCGAGTAAAAACCCACAAAGACGCTGTGATTGGCCGAGGGATGCACTGTGGGCGGGGCAATGCTGAGAGAGCAGATGAAGATGAGCACTTCATGTCCAGCTTCAACATTCCGAATTTTGTGAACTCCGAGCAGAGCTCCAGCCTCGGCCATGACGACTTTCTGCTGAGTGAGCCGCCAATCATCACAGACGGCCAATCAGATGAGCTGAAGACAGCAGAGCCCGCCCATCTCTGCTATGATATCATCAGACATTGA

Function


symbol description
mrap2b Enables signaling receptor regulator activity and type 4 melanocortin receptor binding activity. Involved in energy homeostasis and energy reserve metabolic process. Acts upstream of or within cellular localization; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and response to starvation. Located in Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Is expressed in several structures, including adipose tissue; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2).

GO:

id name namespace
GO:0006112 energy reserve metabolic process biological_process
GO:0042594 response to starvation biological_process
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway biological_process
GO:0051641 cellular localization biological_process
GO:0097009 energy homeostasis biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0031782 type 4 melanocortin receptor binding molecular_function
GO:0030545 receptor regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-100729-5 Enables signaling receptor regulator activity and type 4 melanocortin receptor binding activity. Involved in energy homeostasis and energy reserve metabolic process. Acts upstream of or within cellular localization; positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and response to starvation. Located in Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Is expressed in several structures, including adipose tissue; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2).

Ensembl:

ensembl_id ENSDARG00000103050

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00055129 True 600 mRNA 0.52 3 905483 908821

Neighbor


gene id symbol gene type direction distance location
XLOC_028383 NA coding downstream 1461 899962 ~ 904022 (-)
XLOC_028382 crybg1b coding downstream 15263 861444 ~ 890220 (-)
XLOC_028381 sobpb coding downstream 47049 818928 ~ 858434 (-)
XLOC_028380 dpysl5b coding downstream 89612 798696 ~ 815871 (-)
XLOC_028379 mapre3b coding downstream 107625 783644 ~ 797858 (-)
XLOC_028385 NA coding upstream 10931 919752 ~ 921761 (-)
XLOC_028386 sim1b coding upstream 20736 929557 ~ 948842 (-)
XLOC_028387 atp23 coding upstream 49230 958051 ~ 965267 (-)
XLOC_028388 naga coding upstream 73207 982028 ~ 992148 (-)
XLOC_028389 NA coding upstream 102139 1010960 ~ 1013095 (-)
XLOC_028375 CU855889.2 non-coding downstream 171136 701612 ~ 734347 (-)
XLOC_028376 NA non-coding downstream 172999 723830 ~ 732484 (-)
XLOC_028373 NA non-coding downstream 508664 393551 ~ 396819 (-)
XLOC_028362 NA non-coding downstream 786289 116322 ~ 119194 (-)
XLOC_028391 NA non-coding upstream 113495 1022316 ~ 1023700 (-)
XLOC_028392 NA non-coding upstream 120015 1028836 ~ 1036046 (-)
XLOC_028393 NA non-coding upstream 145840 1054661 ~ 1259741 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000068_00728788_00730622 NA coding CI01000068 null 728558 ~ 730622 (-)