XLOC_003046 (tcf7l1a)


Basic Information

Item Value
gene id XLOC_003046
gene name tcf7l1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 42195732 ~ 42297889 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00005581
TATCTCCAAATGAAATGGCCTCTTCTTGACGTTCCTGCCTCGGCGGCTCTTAAAGACTCCAGATCTCCCACACCAGGACACTTGtcaAATAAGGTTCCAGTGGTACAACACCCCCATCACGTTCATCCGCTCACACCGCTGATCACCTACAGCAATGAACACTTCTCTCCAGGGACGCCTCCTTCTCACCTCTCGCCGGAGATTCTTGACCCAAAGACTGGCATACCAAGGACCCCTCACCCCTCAGAGCTGTCCCCATATTACCCTCTCTCTCCTGGGGCAGTCGGACAGATCCCTCACCCTCTTGGATGGTTGGTTCCTCAGCAAGGCCAGCATATGTACTCCATCCCTCCCGGAGGCTTCAGACACCCCTACCCTGCACTCGCCATGAACGCCTCCATGTCTAGTCTGGTCTCCAGCCGTTTCTCTCCACACATGGTTCCTCATCCTCCTCACGGCCTCCACCAGACGGGCATCCCTCACCCCGCCATTGTGTCGCCTGCCATCAAACAGGAGCCCAATGGCGAGAGCCCCAGCAACTCCACACACGGAAAGCCCTCGGTGCCCGTGAAGAAAGAGGAAGAGAAAAAGCCTCACATCAAGAAGCCTCTTAATGCCTTCATGCTCTACATGAAGGAAATGAGGGCCAAAGTAGTGGCTGAGTGTACCCTGAAAGAGAGCGCCGCCATCAACCAGATCCTGGGCAGAAGGTGGCACTCTCTCTCGCGTGAGGAGCAGGCCAAATACTATGAACTGGCCAGGAAAGAGCGGCAGCTGCACTCTCAGCTTTATCCCGGCTGGTCTGCGAGAGACAACTACGGAAAGAGGAAGAAACGGAAGAGAGACTGTAAATCTGACTCCCCATCAGAGAGTAACTTCTCTCCTCAACCCAAGAAGCAGTGCGTCCCGTATCTGTCATCTGAGAAAATGTGTGACAGCCCTACCTCGTCTCACGGCAGCATGCTGGACTCCCCCGCCACACCCTCCGCCGCCCTGGCGTCCCCCGCGGCTCCAGCGGCCACACACTCAGAGCAGGCGCAGCCCCTGTCCCTCACCACCAAACCCGAAGGCCGAGCTCATCATAACCACCCACACTTCCCTCTGCCAGGCAAATCCTCGGGCTCCGGCTCAGGCTCCAGCATGGCCCTCCACAGCCTCTCGCGCCCCATCCCCTTCACCAGCCTGCCCCCGTCTCTGCTCGGCCCGAACTCGCCGTTCCACCAGGCCGCTCTGCATTCCCATCATGCTTTGCTGCAAACACAACCGCTCTCCCTCGTCACCAAATCTGTGGAgtgaacagacaaaaaaaaaaataaagcgacTTTTTTTACACCTGtatattgctttgtttttttacctTTTGATAGATCATAGGCCGAGTTTTTAAAGATAGAATGAAAAGTGATAATTATTGGTCAATATTTGACCCCCCTTCTATTTTGCTTTTCTCTTTTGAAACCAACgacaatgtatttttttgtaaattgacttttttttctctctcctcaTGTGATTCTCCATTGTTGCTCCCTGTATAAAAGACAAATGTATAAaggttttctgtttgtttaattgttttttaaccGTACTTGACAAATACAGTTTGTAGTTTTAGTTCAATTCAATCTAACGGTAGTTTAGGAGTtcggttaatttttttttcattacagctttctctctttgttttttctattattttatttttctccttCATTCTTTTGGTACCACCTCACCCTGTTCCTAACCCTGTGTGTGTGACTCTCCTAAGGCTCCATAGCTAATAAACCTCAAGTTATTTCTAAA
>TCONS_00005582
GGGATACAAATGTTTCTTTATCCACATTCGAGTCTGTCACCGGAGCCCgattgtaaatattaaacatacaGTCGGAGACGTTCGTGCGCGTTCAATCAAAACCATGGGATTGACACACTGAGCTTTGAGTGTTTGGAAGAGAAACTCTGAAGCGGCTGAAAGTTTTGTATCCACACCTTTTGTTTCGCGAAACTTTTCCTTTCTCTCGTAACTTACTTTTTGCAGGAGTATCCGAAGATTCCAGCAGCGCGGATGGATATTAAATGATGCCCGTGGACTGTTTTGGGGGTTTATTTCAGAGTgttttttgtttggaaataaaaccCCGATTCTTCAACCCACAACCCTTCTGATCTGATCATGGGAAAATTGGGAATGTTGGGTTTTTTCTAACCTCCACAGTCGCGCTTGTAAGATTTGGGGTTAGTTCGGATTACTGCAGCTCTCTTCGTGAGACAGGAAAGTTTCGCTTTAAGCAGACGTTTGGCTTTTCATTTAAAGTGCCAACATGCCTCAGTTAAACGGAGGAGGAGGTGATGACCTGGGAGCAAATGATGAACTTATTTCCTTCAAAGACGAGGGCGAACAAGAGGAGAAAATATCCGAAAATGTGTCGTCGGAGAGAGATCTGGACGAGGTCAAATCCTCACTAGTCAACGAGTCCGAGAACAACAGCAGCTCATCAGACTCCGAACAAACAGATAGACGTCCTCGACCGAGACCAGATCTAGAAAGTTACGAGAAACAGAGGGAATACTTTGCGGAagCTTTGAGACGACAACAAGATGGAGGATTTTTTAAGGGACCCCCTTATGCTGGTTATCCGTTTCTTATGATCCCAGATATCACCAATCCATACCTCTCCAACGGATCGCTATCTCCCAGCACACGAACGTATCTCCAAATGAAATGGCCTCTTCTTGACGTTCCTGCCTCGGCGGCTCTTAAAGACTCCAGATCTCCCACACCAGGACACTTGtcaAATAAGGTTCCAGTGGTACAACACCCCCATCACGTTCATCCGCTCACACCGCTGATCACCTACAGCAATGAACACTTCTCTCCAGGGACGCCTCCTTCTCACCTCTCGCCGGAGATTCTTGACCCAAAGACTGGCATACCAAGGACCCCTCACCCCTCAGAGCTGTCCCCATATTACCCTCTCTCTCCTGGGGCAGTCGGACAGATCCCTCACCCTCTTGGATGGTTGGTTCCTCAGCAAGGCCAGCATATGTACTCCATCCCTCCCGGAGGCTTCAGACACCCCTACCCTGCACTCGCCATGAACGCCTCCATGTCTAGTCTGGTCTCCAGCCGTTTCTCTCCACACATGGTTCCTCATCCTCCTCACGGCCTCCACCAGACGGGCATCCCTCACCCCGCCATTGTGTCGCCTGCCATCAAACAGGAGCCCAATGGCGAGAGCCCCAGCAACTCCACACACGGAAAGCCCTCGGTGCCCGTGAAGAAAGAGGAAGAGAAAAAGCCTCACATCAAGAAGCCTCTTAATGCCTTCATGCTCTACATGAAGGAAATGAGGGCCAAAGTAGTGGCTGAGTGTACCCTGAAAGAGAGCGCCGCCATCAACCAGATCCTGGGCAGAAGGTGGCACTCTCTCTCGCGTGAGGAGCAGGCCAAATACTATGAACTGGCCAGGAAAGAGCGGCAGCTGCACTCTCAGCTTTATCCCGGCTGGTCTGCGAGAGACAACTACGGAAAGAGGAAGAAACGGAAGAGAGACTGTAAATCTGACTCCCCATCAGAGAGTAACTTCTCTCCTCAACCCAAGAAGCAGTGCGTCCCGTATCTGTCATCTGAGAAAATGTGTGACAGCCCTACCTCGTCTCACGGCAGCATGCTGGACTCCCCCGCCACACCCTCCGCCGCCCTGGCGTCCCCCGCGGCTCCAGCGGCCACACACTCAGAGCAGGCGCAGCCCCTGTCCCTCACCACCAAACCCGAAGGCCGAGCTCATCATAACCACCCACACTTCCCTCTGCCAGGCAAATCCTCGGGCTCCGGCTCAGGCTCCAGCATGGCCCTCCACAGCCTCTCGCGCCCCATCCCCTTCACCAGCCTGCCCCCGTCTCTGCTCGGCCCGAACTCGCCGTTCCACCAGGCCGCTCTGCATTCCCATCATGCTTTGCTGCAAACACAACCGCTCTCCCTCGTCACCAAATCTGTGGAgtgaacagacaaaaaaaaaaataaagcgacTTTTTTTACACCTGtatattgctttgtttttttacctTTTGATAGATCATAGGCCGAGTTTTTAAAGATAGAATGAAAAGTGATAATTATTGGTCAATATTTGACCCCCCTTCTATTTTGCTTTTCTCTTTTGAAACCAACgacaatgtatttttttgtaaattgacttttttttctctctcctcaTGTGATTCTCCATTGTTGCTCCCTGTATAAAAGACAAATGTATAAaggttttctgtttgtttaattgttttttaaccGTACTTGACAAATACAGTTTGTAGTTTTAGTTCAATTCAATCTAACGGTAGTTTAGGAGTtcggttaatttttttttcattacagctttctctctttgttttttctattattttatttttctccttCATTCTTTTGGTACCACCTCACCCTGTTCCTAACCCTGTGTGTGTGACTCTCCTAAGGCTCCATAGCTAATAAACCTCAAGTTATTTCT
>TCONS_00005583
attaacagttggacaggtgtacctaataaagtggccggtgagtgtataccgcaatatttattgcagggaaaaaaacattgcaatgtcagatttttccaatatcgtgcagccttattattagtgtattatttataattgttgatgtatttttattgttataaaccttttttgttatttatatgatttatttgtaaagtgtattattattgtaCACCTGTTTTACCaggtttaattgtttaaatggTTTATTCTTATTTATGTATAGTACGTTGAGTTACagttgtgtatgaaatgtgcgtTGGAAATAGTTTTGCCATGAAATATCCAGGGAAGCTGAAACCTAAAATCTCCAAACTTCTCTGAAaatctccctctttctctctctccatgcAGAAAGCCCTCGGTGCCCGTGAAGAAAGAGGAAGAGAAAAAGCCTCACATCAAGAAGCCTCTTAATGCCTTCATGCTCTACATGAAGGAAATGAGGGCCAAAGTAGTGGCTGAGTGTACCCTGAAAGAGAGCGCCGCCATCAACCAGATCCTGGGCAGAAGGTGGCACTCTCTCTCGCGTGAGGAGCAGGCCAAATACTATGAACTGGCCAGGAAAGAGCGGCAGCTGCACTCTCAGCTTTATCCCGGCTGGTCTGCGAGAGACAACTACGGAAAGAGGAAGAAACGGAAGAGAGACTGTAAATCTGACTCCCCATC

Function

symbol description
tcf7l1a Enables DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cell proliferation in dorsal spinal cord; negative regulation of Wnt signaling pathway; and nervous system development. Located in nucleus. Is expressed in several structures, including axis; digestive system; midbrain neural keel; nervous system; and posterior neural tube. Orthologous to human TCF7L1 (transcription factor 7 like 1).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0060900 embryonic camera-type eye formation biological_process
GO:0030178 negative regulation of Wnt signaling pathway biological_process
GO:0007275 multicellular organism development biological_process
GO:0021903 rostrocaudal neural tube patterning biological_process
GO:0010456 cell proliferation in dorsal spinal cord biological_process
GO:0048596 embryonic camera-type eye morphogenesis biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0045892 negative regulation of transcription, DNA-templated biological_process
GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0030900 forebrain development biological_process
GO:0030901 midbrain development biological_process
GO:0022008 neurogenesis biological_process
GO:0048699 generation of neurons biological_process
GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation biological_process
GO:0060323 head morphogenesis biological_process
GO:0060847 endothelial cell fate specification biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function
GO:0005515 protein binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0008013 beta-catenin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980605-30 Enables DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cell proliferation in dorsal spinal cord; negative regulation of Wnt signaling pathway; and nervous system development. Located in nucleus. Is expressed in several structures, including axis; digestive system; midbrain neural keel; nervous system; and posterior neural tube. Orthologous to human TCF7L1 (transcription factor 7 like 1).

Ensembl:

ensembl_id ENSDARG00000038159

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00005581 False 1803 mRNA 0.50 9 42195732 42237304
TCONS_00005582 False 2695 mRNA 0.49 12 42195735 42297889
TCONS_00005583 True 708 lncRNA 0.41 3 42199733 42202832

Neighbor

gene id symbol gene type direction distance location
XLOC_003045 dusp11 coding downstream 48414 42134256 ~ 42147318 (-)
XLOC_003044 stambpa coding downstream 64324 42111288 ~ 42131408 (-)
XLOC_003043 ess2 coding downstream 87595 42089267 ~ 42108137 (-)
XLOC_003042 dgcr2 coding downstream 108502 42044220 ~ 42087230 (-)
XLOC_003041 car15 coding downstream 156563 42027285 ~ 42039169 (-)
XLOC_003047 NA coding upstream 15750 42313639 ~ 42355104 (-)
XLOC_003048 NA coding upstream 172727 42470616 ~ 42473939 (-)
XLOC_003049 march5l coding upstream 203006 42500895 ~ 42519773 (-)
XLOC_003050 stc1l coding upstream 380002 42677891 ~ 42685512 (-)
XLOC_003051 zgc:100918 coding upstream 442973 42740862 ~ 42759918 (-)
XLOC_003040 NA non-coding downstream 209137 41982909 ~ 41986595 (-)
XLOC_003029 CU929265.1 non-coding downstream 1292495 40903121 ~ 40903237 (-)
XLOC_003028 NA non-coding downstream 1338635 40851137 ~ 40857097 (-)
XLOC_003024 BX001050.1 non-coding downstream 1454285 40741330 ~ 40741447 (-)
XLOC_003023 NA non-coding downstream 1573777 40620981 ~ 40621955 (-)
XLOC_003053 FP236542.2 non-coding upstream 501226 42799115 ~ 42870149 (-)
XLOC_003057 CU326366.3 non-coding upstream 614044 42911933 ~ 42912047 (-)
XLOC_003062 NA non-coding upstream 1155282 43453171 ~ 43540184 (-)

Expression


Co-expression Network