XLOC_003052 (wdr45)


Basic Information

Item Value
gene id XLOC_003052
gene name wdr45
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 42762454 ~ 42776344 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00005590
GCAAAAACTGTCGCAAAACACCtctgaatgacattttaaaggCCCATagcatagatatatatacaccAGTAAGGCTAAAACTAAAAGGGCTGTATTAGTTCATATTTCACTTCAGTAAAAGTGTCAACCAAATACACCTCCAGGCCTTTATTGGGAAAGTTCAGACTTTATAACtctaaattctgactttatttatttatttatttatttatttatttatttatttatttatttatttattttggcggGAAGGGGCTTCTCCGTGGTACCACTAATCTCCAGACCAGCAGAGGCGCACATGCGCAGTTCAACATCCCGAATGATCATCCCTAACATAGAAGAAGAAACCAGCGACAATAACAACAACATCGGGCAGATGTTGCCTAATATGAGCGATCAGACTTCAAAAACAGTATAAACTCATTTTTCGTTTACTTACTGATCTTTACCGGGGACTTTTCGCTATCTTATGGTAAGTGTTAAGTCGCGACAAACTCATTATACTGTAAACGGAAGCCGTTTTCTCGTGTTCTTATGGTTGTTATTATTACATGAAATAGCTGATTTCTGCTCATCCAGGAGGATCAAATCTAGAGAATAAACTGCAGAGAAGTCTTCTGTGAGCTGTTCTCGGTCATCATGGCCCAGCAGAGAGGAGTCAACAGCCTGCAGTTCAACCAGGACCAGAGTTGTTTCTGCTGTGCCATGGAGACGGGCGTTCGCATTTATAACGTGGAGCCTTTAATGGAGAAAGGGCATTTAGatCATGAGCAGGTTGGCAGCATCGCTCTGTGTTCAATGCTTCATCGCTCAAACCTGCTGGCTGTGGTCGGCGGCGGCGTCAACCCCAAATTCTCTGAGATTTCAGTATTGATATGGGACGATGCTCGAGAAGTTCGAGACCCGAAGGATAAACTTGTTCTTGAGTTCACGTTCACTAAACCAGTGCTGGCAGTGCGCATGAGACACGACAAAATCATCATCATCCTGAAGAACCGGATCTACGTGTACAGCTTCCCGGATAACCCTGTGAAGCTGTTTGAGTTTGACACTCGTGATAATCCTAAAGGTTTGTGTGATTTGTGTCCCAGTCTGGAAAAACAGCTGCTGGTGTTCCCCGGACACAAATGCGGCAGTCTGCAGTTAGTGGATCTCTCCAACACCAAACCGGGCACTTCTTCGGCCCCGTTCACCATTAACGCGCACCAGAGTGAAATCGCATGTCTGGAGCTGAATCAGCCGGGCAGTGTGGTGGCATCAGCCTCCAGAAAGGGAACACTGATCAGGCTGTTCGACACCACCACACGGGACAAACTGGTGGAGCTGCGAAGAGGAACTGATCCTGCCACACTCTACTGTATTAATTTCAGCCACGACTCCTCTTTTCTGTGCGCATCGAGTGACAAGGGAACTGTGCACATATTTGCCCTGAAAGACACCAAACTGAACCGCCGCTCAGCTTTGGCTCGTGTGGGTAAGGTCGGTCCAGTCATCGGTCAGTATGTGGACAGTCAGTGGTCTCTGGCCAACTTCACAGTTCCTGCAGAGTGCGCGTGTATCTGCGCCTTCGGGAAGAACACCTCCAAaaacgtcaactctgttattgccATATGTGTTGACGGGACGTTCCACAAATACGTTTTCACCCCGGACGGAAACTGCAACCGTGAGGCTTTTGACGTTTATCTGGACATCTGTGATGACGATGACTTCTGA
>TCONS_00005589
GCAAAAACTGTCGCAAAACACCtctgaatgacattttaaaggCCCATagcatagatatatatacaccAGTAAGGCTAAAACTAAAAGGGCTGTATTAGTTCATATTTCACTTCAGTAAAAGTGTCAACCAAATACACCTCCAGGCCTTTATTGGGAAAGTTCAGACTTTATAACtctaaattctgactttatttatttatttatttatttatttatttatttatttatttatttatttattttggcggGAAGGGGCTTCTCCGTGGTACCACTAATCTCCAGACCAGCAGAGGCGCACATGCGCAGTTCAACATCCCGAATGATCATCCCTAACATAGAAGAAGAAACCAGCGACAATAACAACAACATCGGGCAGATGTTGCCTAATATGAGCGATCAGACTTCAAAAACAGTATAAACTCATTTTTCGTTTACTTACTGATCTTTACCGGGGACTTTTCGCTATCTTATGGAGGATCAAATCTAGAGAATAAACTGCAGAGAAGTCTTCTGTGAGCTGTTCTCGGTCATCATGGCCCAGCAGAGAGGAGTCAACAGCCTGCAGTTCAACCAGGACCAGAGTTGTTTCTGCTGTGCCATGGAGACGGGCGTTCGCATTTATAACGTGGAGCCTTTAATGGAGAAAGGGCATTTAGatCATGAGCAGGTTGGCAGCATCGCTCTGTGTTCAATGCTTCATCGCTCAAACCTGCTGGCTGTGGTCGGCGGCGGCGTCAACCCCAAATTCTCTGAGATTTCAGTATTGATATGGGACGATGCTCGAGAAGTTCGAGACCCGAAGGATAAACTTGTTCTTGAGTTCACGTTCACTAAACCAGTGCTGGCAGTGCGCATGAGACACGACAAAATCATCATCATCCTGAAGAACCGGATCTACGTGTACAGCTTCCCGGATAACCCTGTGAAGCTGTTTGAGTTTGACACTCGTGATAATCCTAAAGGTTTGTGTGATTTGTGTCCCAGTCTGGAAAAACAGCTGCTGGTGTTCCCCGGACACAAATGCGGCAGTCTGCAGTTAGTGGATCTCTCCAACACCAAACCGGGCACTTCTTCGGCCCCGTTCACCATTAACGCGCACCAGAGTGAAATCGCATGTCTGGAGCTGAATCAGCCGGGCAGTGTGGTGGCATCAGCCTCCAGAAAGGGAACACTGATCAGGCTGTTCGACACCACCACACGGGACAAACTGGTGGAGCTGCGAAGAGGAACTGATCCTGCCACACTCTACTGTATTAATTTCAGCCACGACTCCTCTTTTCTGTGCGCATCGAGTGACAAGGGAACTGTGCACATATTTGCCCTGAAAGACACCAAACTGAACCGCCGCTCAGCTTTGGCTCGTGTGGGTAAGGTCGGTCCAGTCATCGGTCAGTATGTGGACAGTCAGTGGTCTCTGGCCAACTTCACAGTTCCTGCAGAGTGCGCGTGTATCTGCGCCTTCGGGAAGAACACCTCCAAaaacgtcaactctgttattgccATATGTGTTGACGGGACGTTCCACAAATACGTTTTCACCCCGGACGGAAACTGCAACCGTGAGGCTTTTGACGTTTATCTGGACATCTGTGATGACGATGACTTCTGA

Function

symbol description
wdr45 Predicted to enable phosphatidylinositol-3,5-bisphosphate binding activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including autophagy of mitochondrion; autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to act upstream of or within autophagy. Predicted to be located in phagophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Orthologous to human WDR45 (WD repeat domain 45).

GO:

id name namespace
GO:0009267 cellular response to starvation biological_process
GO:0006914 autophagy biological_process
GO:0000045 autophagosome assembly biological_process
GO:0034497 protein localization to phagophore assembly site biological_process
GO:0000422 autophagy of mitochondrion biological_process
GO:0044804 autophagy of nucleus biological_process
GO:0006497 protein lipidation biological_process
GO:0005829 cytosol cellular_component
GO:0000407 phagophore assembly site cellular_component
GO:0019898 extrinsic component of membrane cellular_component
GO:0034045 phagophore assembly site membrane cellular_component
GO:1901981 phosphatidylinositol phosphate binding molecular_function
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding molecular_function
GO:0032266 phosphatidylinositol-3-phosphate binding molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-040426-990 Predicted to enable phosphatidylinositol-3,5-bisphosphate binding activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including autophagy of mitochondrion; autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to act upstream of or within autophagy. Predicted to be located in phagophore assembly site. Predicted to be active in cytosol and phagophore assembly site membrane. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Orthologous to human WDR45 (WD repeat domain 45).

Ensembl:

ensembl_id ENSDARG00000090219

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00005590 False 1716 mRNA 0.46 10 42762454 42776344
TCONS_00005589 True 1609 mRNA 0.47 11 42762454 42776344

Neighbor

gene id symbol gene type direction distance location
XLOC_003051 zgc:100918 coding downstream 2536 42740862 ~ 42759918 (-)
XLOC_003050 stc1l coding downstream 76942 42677891 ~ 42685512 (-)
XLOC_003049 march5l coding downstream 242681 42500895 ~ 42519773 (-)
XLOC_003048 NA coding downstream 288515 42470616 ~ 42473939 (-)
XLOC_003047 NA coding downstream 407350 42313639 ~ 42355104 (-)
XLOC_003053 FP236542.2 coding upstream 22771 42799115 ~ 42870149 (-)
XLOC_003054 FP236542.1 coding upstream 96819 42873163 ~ 42882215 (-)
XLOC_003055 CU326366.2 coding upstream 110860 42887204 ~ 42898220 (-)
XLOC_003056 ACOT12 coding upstream 126747 42903091 ~ 42923385 (-)
XLOC_003057 CU326366.3 coding upstream 135589 42911933 ~ 42912047 (-)
XLOC_003040 NA non-coding downstream 775859 41982909 ~ 41986595 (-)
XLOC_003029 CU929265.1 non-coding downstream 1859217 40903121 ~ 40903237 (-)
XLOC_003028 NA non-coding downstream 1905357 40851137 ~ 40857097 (-)
XLOC_003062 NA non-coding upstream 676827 43453171 ~ 43540184 (-)
XLOC_003063 NA non-coding upstream 708283 43484627 ~ 43496216 (-)
XLOC_003064 dre-mir-9-2 non-coding upstream 759616 43535960 ~ 43536095 (-)

Expression


Co-expression Network