XLOC_032187 (gabrb3)


Basic Information

Item Value
gene id XLOC_032187
gene name gabrb3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 38381957 ~ 38513578 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00062885
cacacacacacacacacactcgtctgtctctctctctttcaatagTTCCATCCATTCTGTCAGGCCAGGCCTCTACGTTTGGGATATACTCTTTCTCTGCTTGCATAAAGGGGCAACTAAAAAGGGGGGCAAACAGCACCAAATCTAGTCTGGATCAGAGGAGACGGATCAAGTGGATCAGATGAAGATGATGACAAGCTGTTGAGCCTTGGAAGTCAAGGAAAAGTTTGAACATTGTGAGGGCCCTGGGGGCAAAGATGTCCTCGTCACGAGGGGCTCGACGCATCCCCTTCATCTCGCACTGCCCTTTATTTCAATGACCGGGAAGAAAGCACATCTGGCAGTGCCCCATTTCAAATATTCCGCCTTGGATGCGCCTTGCCGGGTGGGACTCTTTGAGAGCTGAAAACATGCGACTGTGGTGGATTTTACTGCTAAGCTTTTGGAGTGTTTATGGAGAACTCCCATTCATAGCAGAAAACAACGCTGCCATGCTGGTCAACTGGAATGCTGTGGATGGAAATAAAAAGCTGTTTGCAATTTATGACACAAGcgCCAATGAACCAGGAAACATGTCTTTTGTCAAAGAGACAGTAGACAAGCTTTTGAAAGGCTATGATATTCGTCTACGACCAGATTTTGGAGGTGCACCGGTTGCAGTTGGCATGAGTATTGATGTGGCGAGCATAGACATGGTGTCTGAGGTCAACATGGACTACACGTTGACCATGTATTTCCAACAGTACTGGAGGGACAAGCGGCTGGCATATACTGGGATTCCTCTTAATCTCACTTTAGATAACAGAGTAGCTGACCAGCTCTGGGTTCCTGACACATATTTCCTAAATGACAAAAAGTCTTTTGTACACGGCGTCACAGTGAAGAACCGCATGATCCGCCTGCATCCAGATGGGACAGTTCTTTATGGATTAAGAATCACTACGACTGCTGCTTGCATGATGGATCTGAGAAGGTATCCATTAGATGAGCAGAATTGCACTCTGGAGATTGAGAGTTATGGATACACAACAGATGACATCGAGTTTTACTGGAAGGGAGGAGAAACCGCAGTGACGGGTGTGTCACGCATCGAGCTCCCGCAGTTCTCCATCGTTGACTACAAACTTGTGTCCAGAAATGTTGTCTTTTCCACAGGTGCCTATCCTCGACTATCTTTGAGCTTCAAGCTAAAAAGAAACATCGGCTACTTCATCCTGCAGACCTACATGCCCTCGATCCTGATCACCATCCTGTCCTGGGTCTCCTTCTGGATCAACTACGATGCCTCAGCAGCCCGAGTGGCATTAGGTATCACCACTGTGCTGACCATGACCACAATCAACACCCACTTGAGAGAAACTCTACCGAAGATTCCATATGTCAAAGCAATAGACATGTATCTGATGGGCTGCTTCGTCTTTGTTTTCTTGGCTCTGCTGGAATACGCTTTCGTCAACTACATTTTCTTTGGACGAGGGCCTCAGATGCAGAAGAAATTGGCTGAGAAAGCTGAGAAAGCCAATAATGACCGCAACAAGTATGACGGCAACAAGTCTGTTCAAGAGGGAGGAAACTGCAAGCCATCATCTGTTAAACAGTCCAATCAGGTACAAGGCCACCGTCACTCACGagggGTGGACTCCCAGGGAAATATTCTTCTGACCACCCTGGAGATCCACAACGAGGTGGCCGGGAACGAGATCACCACCAGCGTCAGCGAGGCTCGAAACTCCACTTCAATGGTGTTCGATAACTCAGGGATCCAGTATCGCAAACAGAGCACAGCGCGGCACAGCATGGACAGAAACGCACAGTCCAAGAAACCGCGACTACGCAGACGCTCTTCACAGCTCAAAATCAAAATCCCTGACCTCACAGACGTGAACGCCATCGACCGATGGTCACGGATTATATTTCCCGCAGTTTTCTCGCTTTTCAACTTGATCTATTGGCTGTATTATGTGAATTAGGCCTCAGGCGTCCGTTGGGTTTTTTTGGCCCTTCACGATTTTTTCATGTTGCCAAGTGgaaaattagactttttttttctttctttgctctGATGTACTTTACGGACGTGCTCGCACGCCATAttgaatttttttacatttgaaccCTTGTGATGTTATAAAGGGTTGGGACTGAATGCTACCTGCACTAAATGGGCCGTCCCGTACAGTACATTTCCAGTGACATCAACAAAATCAGTTTTCTAAAGATACATGTCATAATTTCCGAAGCCACAGGACTTCCGCATGATGCATTCAgagctgtttttaatttgtacATGTTGCTATGTTATTCCGATCGAAAGACTGCTAATGTTTCATGCCAATACGTCTTTACTGTTGGAGCACAGGGGATGAATATTAAAAGAAGACTATATAGTTATGGAAATGCAATATAACAAGGGTTGTAGTTCAAATCACGTCTTCAAAACATTGTCATTATGATCTTATTTAGACGACGTTTGTATATAATCATGTCACGATATGCTTTTGGAACATGATTTCCATCCGCCTTGGGTTGATATGATTATGCGCCACTTTTTGCAATCATCATGTAAAGTGCTTCAGTACATGTACGATAAGATAATAACTGTTCACTCAAGGATATCAACAACAACTAAAATGAGAAAAGGAACAAAAAAGGGGAATATTTAAATCAGGGCCTGCAAAGGATTTCCATGATGCCATCCTGAACATCAAACACAAGAAGACGAACAATCCTCACattgtgttttgctttttgttagtAGACGTGTAGCAATGACTTTGATTTTCAAGTGAGGTTTGGGTGTTTTGTtcccctccttttttttttaagtatgcctGAGTCATTTCACATATCATCGTAGGCCTTTTGGAAACATCATATGGGCCCACTTACATCTTCATCCTTTTCCCTTCCTGAAAGGGGTTATTTACATGAACGCATTTGAGGGAATTGTATGCTGGCATCAACACATAACTTGTCTCAGGTTCTCTTCCAACAAGAAAATGATCCGTATTTTTCTGATCGTCAGTATTCGCATCATCTTTGTTGTGATTAATTTGTATTATATCCTTGTGTACAGCAACGATTACATAGCAGATTTAGAGCGCATGATATTGTTTGCATTTTGCGATTCTACagtgactgtatccgatttttgTTTTGGCAGATTTCTTTACCACCAGTCATATGCACTTACTCAGTTTCTGGGGCCGAAAACTGCTGTCTGGTTAGAGAGTAATGTATTCTCATGCTTGCAAACcatcaaatatatttataaatctcTTTAAAATATCCCGTGTGTGCTGTTAACATGTCATTTAACAGGTTGCTTTGCAGTTACATTGTGTCAGTAGATGCTCATTAATTCTTGAATTACTTTTCTTCCCTCTTCTATTGTATGTTGTAAATATATAACCCACGATCCACACATGATCCATTTCTCTGTTCCCTTTTTTTCTAATATTCACTTCTGAGGTTTTATTCTGTACAAATGACAAGAACTCTATTTATGAAATGTGTTTAAACTATTAGACATATGAGGGGTGAATGTCCAAAGGACAACATGAGGAAATGGAATAAACTTTACTCTTTCAAGTA
>TCONS_00062886
ATGCATTGTATTCCCCGAGCACCTAACCAAAAAACGCAGTCTCCGCAAGAGAGCGAAAACCCGGATCGCGGCGATTTGTTTACGCGTGCTTGACAGTAATTGGAGTTCTTTAGCAAAGACACACTGATGGAATAACGTAACCTGTTACCTAAGCAAGAAAACCTTACAACGTCCGTTTTGTCGCTCAGTtccttgtctgaaagagtataaggAATGTTTGGAATACAGAAACGAAGGCTGTTTGGAGTTCTTTCATTACCGGTAATTGTGGCAGTGATGTGCTGTGCTCAAAGcgCCAATGAACCAGGAAACATGTCTTTTGTCAAAGAGACAGTAGACAAGCTTTTGAAAGGCTATGATATTCGTCTACGACCAGATTTTGGAGGTGCACCGGTTGCAGTTGGCATGAGTATTGATGTGGCGAGCATAGACATGGTGTCTGAGGTCAACATGGACTACACGTTGACCATGTATTTCCAACAGTACTGGAGGGACAAGCGGCTGGCATATACTGGGATTCCTCTTAATCTCACTTTAGATAACAGAGTAGCTGACCAGCTCTGGGTTCCTGACACATATTTCCTAAATGACAAAAAGTCTTTTGTACACGGCGTCACAGTGAAGAACCGCATGATCCGCCTGCATCCAGATGGGACAGTTCTTTATGGATTAAGAATCACTACGACTGCTGCTTGCATGATGGATCTGAGAAGGTATCCATTAGATGAGCAGAATTGCACTCTGGAGATTGAGAGTTATGGATACACAACAGATGACATCGAGTTTTACTGGAAGGGAGGAGAAACCGCAGT
>TCONS_00062887
ATGTTTGGAATACAGAAACGAAGGCTGTTTGGAGTTCTTTCATTACCGGTAATTGTGGCAGTGATGTGCTGTGCTCAAAGcgCCAATGAACCAGGAAACATGTCTTTTGTCAAAGAGACAGTAGACAAGCTTTTGAAAGGCTATGATATTCGTCTACGACCAGATTTTGGAGGTGCACCGGTTGCAGTTGGCATGAGTATTGATGTGGCGAGCATAGACATGGTGTCTGAGGTCAACATGGACTACACGTTGACCATGTATTTCCAACAGTACTGGAGGGACAAGCGGCTGGCATATACTGGGATTCCTCTTAATCTCACTTTAGATAACAGAGTAGCTGACCAGCTCTGGGTTCCTGACACATATTTCCTAAATGACAAAAAGTCTTTTGTACACGGCGTCACAGTGAAGAACCGCATGATCCGCCTGCATCCAGATGGGACAGTTCTTTATGGATTAAGAATCACTACGACTGCTGCTTGCATGATGGATCTGAGAAGGTATCCATTAGATGAGCAGAATTGCACTCTGGAGATTGAGAGTTATGGATACACAACAGATGACATCGAGTTTTACTGGAAGGGAGGAGAAACCGCAGTGACGGGTGTGTCACGCATCGAGCTCCCGCAGTTCTCCATCGTTGACTACAAACTTGTGTCCAGAAATGTTGTCTTTTCCACAGGTGCCTATCCTCGACTATCTTTGAGCTTCAAGCTAAAAAGAAACATCGGCTACTTCATCCTGCAGACCTACATGCCCTCGATCCTGATCACCATCCTGTCCTGGGTCTCCTTCTGGATCAACTACGATGCCTCAGCAGCCCGAGTGGCATTAGGTATCACCACTGTGCTGACCATGACCACAATCAACACCCACTTGAGAGAAACTCTACCGAAGATTCCATATGTCAAAGCAATAGACATGTATCTGATGGGCTGCTTCGTCTTTGTTTTCTTGGCTCTGCTGGAATACGCTTTCGTCAACTACATTTTCTTTGGACGAGGGCCTCAGATGCAGAAGAAATTGGCTGAGAAAGCTGAGAAAGCCAATAATGACCGCAACAAGTATGACGGCAACAAGTCTGTTCAAGAGGGAGGAAACTGCAAGCCATCATCTGTTAAACAGTCCAATCAGGTACAAGGCCACCGTCACTCACGagggGTGGACTCCCAGGGAAATATTCTTCTGACCACCCTGGAGATCCACAACGAGGTGGCCGGGAACGAGATCACCACCAGCGTCAGCGAGGCTCGAAACTCCACTTCAATGGTGTTCGATAACTCAGGGATCCAGTATCGCAAACAGAGCACAGCGCGGCACAGCATGGACAGAAACGCACAGTCCAAGAAACCGCGACTACGCAGACGCTCTTCACAGCTCAAAATCAAAATCCCTGACCTCACAGACGTGAACGCCATCGACCGATGGTCACGGATTATATTTCCCGCAGTTTTCTCGCTTTTCAACTTGATCTATTGGCTGTATTATGTGAATTAGGCCTCAGGCGTCCGTTGGGTTTTTTTGGCCCTTCACGATTTTTTCATGTTGCCAAGTGgaaaattagactttttttttctttctttgctctGATGTACTTTACGGACGTGCTCGCACGCCATAttgaatttttttacatttgaaccCTTGTGATGTTATAAAGGGTTGGGACTGAATGCTACCTGCACTAAATGGGCCGTCCCGTACAGTACATTTCCAGTGACATCAACAAAATCAGTTTTCTAAAGATACATGTCATAATTTCCGAAGCCACAGGACTTCCGCATGATGCATTCAgagctgtttttaatttgtacATGTTGCTATGTTATTCCGATCGAAAGACTGCTAATGTTTCATGCCAATACGTCTTTACTGTTGGAGCACAGGGGATGAATATTAAAAGAAGACTATATAGTTATGGAAATGCAATATAACAAGGGTTGTAGTTCAAATCACGTCTTCAAAACATTGTCATTATGATCTTATTTAGACGACGTTTGTATATAATCATGTCACGATATGCTTTTGGAACATGATTTCCATCCGCCTTGGGTTGATATGATTATGCGCCACTTTTTGCAATCATCATGTAAAGTGCTTCAGTACATGTACGATAAGATAATAACTGTTCACTCAAGGATATCAACAACAACTAAAATGAGAAAAGGAACAAAAAAGGGGAATATTTAAATCAGGGCCTGCAAAGGATTTCCATGATGCCATCCTGAACATCAAACACAAGAAGACGAACAATCCTCACattgtgttttgctttttgttagtAGACGTGTAGCAATGACTTTGATTTTCAAGTGAGGTTTGGGTGTTTTGTtcccctccttttttttttaagtatgcctGAGTCATTTCACATATCATCGTAGGCCTTTTGGAAACATCATATGGGCCCACTTACATCTTCATCCTTTTCCCTTCCTGAAAGGGGTTATTTACATGAACGCATTTGAGGGAATTGTATGCTGGCATCAACACATAACTTGTCTCAGGTTCTCTTCCAACAAGAAAATGATCCGTATTTTTCTGATCGTCAGTATTCGCATCATCTTTGTTGTGATTAATTTGTATTATATCCTTGTGTACAGCAACGATTACATAGCAGATTTAGAGCGCATGATATTGTTTGCATTTTGCGATTCTACagtgactgtatccgatttttgTTTTGGCAGATTTCTTTACCACCAGTCATATGCACTTACTCAGTTTCTGGGGCCGAAAACTGCTGTCTGGTTAGAGAGTAATGTATTCTCATGCTTGCAAACcatcaaatatatttataaatctcTTTAAAATATCCCGTGTGTGCTGTTAACATGTCATTTAACAGGTTGCTTTGCAGTTACATTGTGTCAGTAGATGCTCATTAATTCTTGAATTACTTTTCTTCCCTCTTCTATTGTATGTTGTAAATATATAACCCACGATCCACACATGATCCATTTCTCTGTTCCCTTTTTTTCTAATATTCACTTCTGAGGTTTTATTCTGTACAAATGACAAGAACTCTATTTATGAAATGTGTTTAAACTATTAGACATATGAGGGGTGAATGTCCAAAGGACAACATGAGGAAATGGAATAAACTTTACTCTTTCAAGTAGTTGATTTTGCCTTATTTCATATACTAATGAGGTGCTTTTAATGTGAAACATG

Function

symbol description
gabrb3 Predicted to enable neurotransmitter receptor activity. Predicted to contribute to GABA-A receptor activity and chloride channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to act upstream of or within chloride transport. Predicted to be integral component of membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in eye and telencephalon. Human ortholog(s) of this gene implicated in childhood absence epilepsy and developmental and epileptic encephalopathy 43. Orthologous to human GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3).

GO:

id name namespace
GO:0042391 regulation of membrane potential biological_process
GO:0050877 nervous system process biological_process
GO:0034220 ion transmembrane transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:1902476 chloride transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0007165 signal transduction biological_process
GO:0043005 neuron projection cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:1902711 GABA-A receptor complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0004890 GABA-A receptor activity molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005230 extracellular ligand-gated ion channel activity molecular_function
GO:0005254 chloride channel activity molecular_function
GO:0030594 neurotransmitter receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-101102-2 Predicted to enable neurotransmitter receptor activity. Predicted to contribute to GABA-A receptor activity and chloride channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to act upstream of or within chloride transport. Predicted to be integral component of membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in eye and telencephalon. Human ortholog(s) of this gene implicated in childhood absence epilepsy and developmental and epileptic encephalopathy 43. Orthologous to human GABRB3 (gamma-aminobutyric acid type A receptor subunit beta3).

Ensembl:

ensembl_id ENSDARG00000023771

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00062885 False 3594 mRNA 0.43 11 38381957 38513525
TCONS_00062886 False 812 mRNA 0.45 6 38427357 38476961
TCONS_00062887 True 3174 mRNA 0.42 10 38427570 38513578

Neighbor

gene id symbol gene type direction distance location
XLOC_032186 CR405707.1 coding upstream 4746 38377091 ~ 38377211 (+)
XLOC_032185 NA coding upstream 21514 38358681 ~ 38360443 (+)
XLOC_032184 AL935047.1 coding upstream 294346 38087495 ~ 38087611 (+)
XLOC_032183 oca2 coding upstream 327106 37894220 ~ 38054851 (+)
XLOC_032182 herc2 coding upstream 534082 37752781 ~ 37847875 (+)
XLOC_032188 CR628341.3 coding downstream 4641 38518219 ~ 38590172 (+)
XLOC_032189 atp10a coding downstream 113106 38626684 ~ 38730530 (+)
XLOC_032190 ube3a coding downstream 259798 38773376 ~ 38790064 (+)
XLOC_032191 stk35l coding downstream 332098 38845676 ~ 38861349 (+)
XLOC_032192 bin2b coding downstream 366383 38879961 ~ 38894366 (+)
XLOC_032178 NA non-coding upstream 905856 37470116 ~ 37476101 (+)
XLOC_032176 BX324166.1 non-coding upstream 1046994 37334559 ~ 37334963 (+)
XLOC_032194 NA non-coding downstream 439903 38953481 ~ 38955126 (+)
XLOC_032204 NA non-coding downstream 856757 39370335 ~ 39378734 (+)
XLOC_032208 NA non-coding downstream 1018900 39532478 ~ 39541448 (+)
XLOC_032209 AL954698.2 non-coding downstream 1152769 39666347 ~ 39667572 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_08547042_08577482 NA coding CI01000340 null 8546899 ~ 8577918 (+)