XLOC_003220 (thop1)


Basic Information

Item Value
gene id XLOC_003220
gene name thop1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 7183025 ~ 7212097 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00006345
ATGAGCTCCCCAGGTGGTCATGTGACCGGAGCAGGAAGAATGAGTGAGCGGTTATTATAGGTGCTTTGAATCGTTGGTACACGCGGTGTTCTGATTGAGTCGAGAAATGGCACCTACAGGTGAAGTTGTGTTTGGCTCTGGGGATCGAGTTTGTGACGACAACCGTTTGCGCTGGGACCTCACCCCAGAGCAGATCAACCAACTTACCGAAGAGCTTATTGCTAAGACTAAAAAGGTGTATGACACCGTTGGTGCTCTGGACTTGGACAGTGTCAACTATGAGAACACCCTAAAGGCCCTCGCTGATGTGGAAGTGGAGTACACAGtccAGCGGAACATGTTGGATTTTCCTCAACACGTGTCCTCCAGTAAGGACGTCCGTTCAGCAAGCACCGAGGCTGATAAGAAGCTGTCAGAGTTTGATGTGGAGATGAGCATGAGAGAAGATGTTTATCAGCGAATCGTGGCTCTAGAGGAGAAGCTGCCAGAAGGCAGTTTGTCGCCTGAGGCCAAGCGTTACATGGAAAGACTTATAAAGCTTGGCAAGAGAAACGGCCTCCATCTTCCCAAAGTGACACAGGAGGAGATCAAAAAGATCAAGAAGAAACTGAGCACCCTGTGTATCGATTTCAACAAACACCTGAATGAAGATACAACTTGCCTGCATTTCTCTCGAGAGGAGCTTGGGGGGCTCCCTGAGGATTTCCTTAACTCTCTGGAGAAGGATGAGTCTGGAAAACTGAAGCTCACTCTGAAGTATCCTCATTATTTCCCCACCATGAAAAAATGCTTTGTCCCCGAGACACGGAAGAAATTAGAGGAGGCCTTCAACTCGCGCTGCAAAGAGGAGAACTCTGCTATCCTGAAGGAGCTTGTGAATTTGCGCGCTCAGAAGAGCAGCCTGCTGGGCTTCAGCACGCATTCTGACTTTGTTCTTGAGATGAACATGGCCAAGTCATCCAAGAAAGTTTCCACTTTTCTCGAGGACCTTTCGCATAAGCTAAAGCCCCTGGGTGAGAAGGAAAGGGCCGTAATCCTGAAGCTAAAGGAACAGGAGTGCCAGAAGAGGAATCTGCCCTTCACTGGAGAACTTTACGCATGGGACACGCGCTACTACATGACCCAGGTGGAGGAGACCCAGTATGCAGTGGATCAGAACCAGCTGAAGGAGTATTTTCCAATGGAGGTGGTTACCAAGGGCCTGCTGGACATCTATCAGGAGCTGCTAAACCTCACCTTTGAGCAAGTAGAGGGCGCTCCAGTCTGGCATGACGATGTGTCGCTGTACTGCGTTAAAGACCGTTCATCTGGCCTGGTGGTGGGCCAGTTTTATCTGGATCTATTCCCCAGGGAGGGCAAGTACGGCCATGCCGCATGCTTTGGCTTGCAGCCTGGCTGCTTGCTCCCAAATGGGACCCGGCAGATGGCCGTGGCTGCCATGGTGGCTAATTTCAGCAAGCCCACCGCAGATGCACCATCCCTGCTGCAGCATGATGAAGTGGAAACGTACTTCCATGAGTTTGGACATGTGATGCATCAGCTTTGCGCTCAGtcTGATTTTGCAATGTTCAGCGGGACTCACGTAGAAAGGGATTTTGTTGAAGCTCCATCTCAGATGTTGGAGAACTGGGTCTGGGAGAAGGAGCCCATTCAGCGCATGTCCAAGCACTACAAAACAGGAAACCCAATTCCAGAGGAGCTTCTGGATAAGCTCATTAAGTCCAGACTCGCTAACACCGGGTTGTTTAACTTGAGGCAGATTGTTCTGGCTAAGGTGGACCAGGCGTTGCACACAAAGACTGGACTTGACCCAGCTGAAGAATATGCCAGACTCTGCTTGGACATCCTGGGAATTCCTTCTTCACCAGGGACAAACATGCCTGCCACATTTGGTCACCTAGCTGGAGGGTATGATGCTCAGTACTATGGCTACTTGTGGAGTGAGGTGTTCTCCATGGACATGTTCTACGCCCGCTTCAAACAAGAAGGCGTAATGGACCCTAAGgtGGGTCTGGACTACAGGAATTGCATTCTGAAGCCAGGAGGCTCTGAGGATGCTGCTGACATGCTGAAGAAGTTCCTGGGAAGAGAACCCAAGCAGGATGCTTTCCTCCTAAGCAAAGGGCTCACGGCTGATGTGGAGTCTGGCACCCCCTGCGCCTGCTGACCGCCTGAACGCTAGGCCAAGTTGATAAAACCTCAGACTGATACCTCTCAAAAACCCTAAAAAGCTCATTCACTCATCACCACCTCTCCCGAATCGCACTTCTGCAAAGAGCTTTCACTATGGATGTATAAAACCTTGTTTTAGAATTGAAAATTGTATTGAAATCTGTCTCCAAAATGAAAAAGAATCTTTAAATCA
>TCONS_00006346
GCGGTTATTATAGGTGCTTTGAATCGTTGGTACACGCGGTGTTCTGATTGAGTCGAGAAATGGCACCTACAGtccAGCGGAACATGTTGGATTTTCCTCAACACGTGTCCTCCAGTAAGGACGTCCGTTCAGCAAGCACCGAGGCTGATAAGAAGCTGTCAGAGTTTGATGTGGAGATGAGCATGAGAGAAGATGTTTATCAGCGAATCGTGGCTCTAGAGGAGAAGCTGCCAGAAGGCAGTTTGTCGCCTGAGGCCAAGCGTTACATGGAAAGACTTATAAAGCTTGGCAAGAGAAACGGCCTCCATCTTCCCAAAGTGACACAGGAGGAGATCAAAAAGATCAAGAAGAAACTGAGCACCCTGTGTATCGATTTCAACAAACACCTGAATGAAGATACAACTTGCCTGCATTTCTCTCGAGAGGAGCTTGGGGGGCTCCCTGAGGATTTCCTTAACTCTCTGGAGAAGGATGAGTCTGGAAAACTGAAGCTCACTCTGAAGTATCCTCATTATTTCCCCACCATGAAAAAATGCTTTGTCCCCGAGACACGGAAGAAATTAGAGGAGGCCTTCAACTCGCGCTGCAA
>TCONS_00006347
GTGCTTTGAATCGTTGGTACACGCGGTGTTCTGATTGAGTCGAGAAATGGCACCTACAGGGCAAGAAGTAACAGCTGATCATGCTTTTAATTTGGTTTTCTTTTGCTTATGCATACTCTCAGGTGAAGTTGTGTTTGGCTCTGGGGATCGAGTTTGTGACGACAACCGTTTGCGCTGGGACCTCACCCCAGAGCAGATCAACCAACTTACCGAAGAGCTTATTGCTAAGACTAAAAAGGTGTATGACACCGTTGGTGCTCTGGACTTGGACAGTGTCAACTATGAGAACACCCTAAAGGCCCTCGCTGATGTGGAAGTGGAGTACACAGtccAGCGGAACATGTTGGATTTTCCTCAACACGTGTCCTCCAGTAAGGACGTCCGTTCAGCAAGCACCGAGGCTGATAAGAAGCTGTCAGAGTTTGATGTGGAGATGAGCATGAGAGAAGATGTTTATCAGCGAATCGTGGCTCTAGAGGAGAAGCTGCCAGAAGGCAGTTTGTCGCCTGAGGCCAAGCGTTACATGGAAAGACTTATAAAGCTTGGCAAGAGAAACGGCCTCCATCTTCCCAAAGTGACACAGGAGGAGATCAAAAAGATCAAGAAGAAACTGAGCACCCTGTGTATCGATTTCAACAAACACCTGAATGAAGATACAACTTGCCTGCATTTCTCTCGAGAGGAGCTTGGGGGGCTCCCTGAGGATTTCCTTAACTCTCTGGAGAAGGATGAGTCTGGAAAACTGAAGCTCACTCTGAAGTATCCTCATTATTTCCCCACCATGAAAAAATGCTTTGTCCCCGAGACACGGAAGAAATTAGAGGAGGCCTTCAACTCGCGCTGCAAAGAGGAGAACTCTGCTATCCTGAAGGAGCTTGTGAATTTGCGCGCTCAGAAGAGCAGCCTGCTGGGCTTCAGCACGCATTCTGACTTTGTTCTTGAGATGAACATGGC
>TCONS_00006348
ATGGCACCTACAGGGCAAGAAGTAACAGCTGATCATGCTTTTAATTTGGTTTTCTTTTGCTTATGCATACTCTCAGGTGAAGTTGTGTTTGGCTCTGGGGATCGAGTTTGTGACGACAACCGTTTGCGCTGGGACCTCACCCCAGAGCAGATCAACCAACTTACCGAAGAGCTTATTGCTAAGACTAAAAAGGTGTATGACACCGTTGGTGCTCTGGACTTGGACAGTGTCAACTATGAGAACACCCTAAAGGCCCTCGCTGATGTGGAAGTGGAGTACACAGtccAGCGGAACATGTTGGATTTTCCTCAACACGTGTCCTCCAGTAAGGACGTCCGTTCAGCAAGCACCGAGGCTGATAAGAAGCTGTCAGAGTTTGATGTGGAGATGAGCATGAGAGAAGATGTTTATCAGCGAATCGTGGCTCTAGAGGAGAAGCTGCCAGAAGGCAGTTTGTCGCCTGAGGCCAAGCGTTACATGGAAAGACTTATAAAGCTTGGCAAGAGAAACGGCCTCCATCTTCCCAAAGTGACACAGGAGGAGATCAAAAAGATCAAGAAGAAACTGAGCACCCTGTGTATCGATTTCAACAAACACCTGAATGAAGATACAACTTGCCTGCATTTCTCTCGAGAGGAGCTTGGGGGGCTCCCTGAGGATTTCCTTAACTCTCTGGAGAAGGATGAGTCTGGAAAACTGAAGCTCACTCTGAAGTATCCTCATTATTTCCCCACCATGAAAAAATGCTTTGTCCCCGAGACACGGAAGAAATTAGAGGAGGCCTTCAACTCGCGCTGCAAAGAGGAGAACTCTGCTATCCTGAAGGAGCTTGTGAATTTGCGCGCTCAGAAGAGCAGCCTGCTGGGCTTCAGCACGCATTCTGACTTTGTTCTTGAGATGAACATGGCCAAGTCATCCAAGAAAGTTTCCACTTTTCTCGAGGACCTTTCGCATAAGCTAAAGCCCCTGGGTGAGAAGGAAAGGGCCGTAATCCTGAAGCTAAAGGAACAGGAGTGCCAGAAGAGGAATCTGCCCTTCACTGGAGAACTTTACGCATGGGACACGCGCTACTACATGACCCAGGTGGAGGAGACCCAGTATGCAGTGGATCAGAACCAGCTGAAGGAGTATTTTCCAATGGAGGTGGTTACCAAGGGCCTGCTGGACATCTATCAGGAGCTGCTAAACCTCACCTTTGAGCAAGTAGAGGGCGCTCCAGTCTGGCATGACGATGTGTCGCTGTACTGCGTTAAAGACCGTTCATCTGGCCTGGTGGTGGGCCAGTTTTATCTGGATCTATTCCCCAGGGAGGGCAAGTACGGCCATGCCGCATGCTTTGGCTTGCAGCCTGGCTGCTTGCTCCCAAATGGGACCCGGCAGATGGCCGTGGCTGCCATGGTGGCTAATTTCAGCAAGCCCACCGCAGATGCACCATCCCTGCTGCAGCATGATGAAGTGGAAACGTACTTCCATGAGTTTGGACATGTGATGCATCAGCTTTGCGCTCAGtcTGATTTTGCAATGTTCAGCGGGACTCACGTAGAAAGGGATTTTGTTGAAGCTCCATCTCAGATGTTGGAGAACTGGGTCTGGGAGAAGGAGCCCATTCAGCGCATGTCCAAGCACTACAAAACAGGAAACCCAATTCCAGAGGAGCTTCTGGATAAGCTCATTAAGTCCAGACTCGCTAACACCGGGTTGTTTAACTTGAGGCAGATTGTTCTGGCTAAGGTGGACCAGGCGTTGCACACAAAGACTGGACTTGACCCAGCTGAAGAATATGCCAGACTCTGCTTGGACATCCTGGGAATTCCTTCTTCACCAGGGACAAACATGCCTGCCACATTTGGTCACCTAGCTGGAGGGTATGATGCTCAGTACTATGGCTACTTGTGGAGTGAGGTGTTCTCCATGGACATGTTCTACGCCCGCTTCAAACAAGAAGGCGTAATGGACCCTAAGgtGGGTCTGGACTACAGGAATTGCATTCTGAAGCCAGGAGGCTCTGAGGATGCTGCTGACATGCTGAAGAAGTTCCTGGGAAGAGAACCCAAGCAGGATGCTTTCCTCCTAAGCAAAGGGCTCACGGCTGATGTGGAGTCTGGCACCCCCTGCGCCTGCTGA

Function

symbol description
thop1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to be active in mitochondrial intermembrane space. Is expressed in lens. Orthologous to human THOP1 (thimet oligopeptidase 1).

GO:

id name namespace
GO:0006508 proteolysis biological_process
GO:0006518 peptide metabolic process biological_process
GO:0005758 mitochondrial intermembrane space cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004222 metalloendopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008237 metallopeptidase activity molecular_function

KEGG:

id description
ko04614 Renin-angiotensin system
ko05143 African trypanosomiasis
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-040718-47 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to be active in mitochondrial intermembrane space. Is expressed in lens. Orthologous to human THOP1 (thimet oligopeptidase 1).

Ensembl:

ensembl_id ENSDARG00000013776

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00006345 False 2365 mRNA 0.50 13 7183025 7212097
TCONS_00006346 False 589 mRNA 0.48 5 7183072 7194753
TCONS_00006347 False 954 mRNA 0.48 8 7183085 7194962
TCONS_00006348 True 2124 mRNA 0.50 14 7183131 7211899

Neighbor

gene id symbol gene type direction distance location
XLOC_003219 tmem38a coding upstream 3509 7158723 ~ 7179516 (+)
XLOC_003217 NA coding upstream 31018 7149071 ~ 7152007 (+)
XLOC_003218 CU929070.2 coding upstream 32119 7150820 ~ 7150906 (+)
XLOC_003216 CR925817.1 coding upstream 79489 7095176 ~ 7103536 (+)
XLOC_003214 crtc1b coding upstream 224983 6902306 ~ 6958042 (+)
XLOC_003221 nwd1 coding downstream 2256 7214353 ~ 7246987 (+)
XLOC_003222 reep6 coding downstream 49884 7261981 ~ 7274378 (+)
XLOC_003223 si:ch73-238c9.1 coding downstream 64727 7276824 ~ 7280259 (+)
XLOC_003224 NA coding downstream 69142 7281239 ~ 7286310 (+)
XLOC_003225 diras1a coding downstream 112607 7324704 ~ 7341807 (+)
XLOC_003250 BX324177.11 misc downstream 4133706 11345803 ~ 11346099 (+)
XLOC_003255 BX324177.14 misc downstream 4160789 11372886 ~ 11373182 (+)
XLOC_003257 BX324177.13 misc downstream 4174265 11386362 ~ 11386658 (+)
XLOC_003260 BX324177.2 misc downstream 4205936 11418033 ~ 11418323 (+)
XLOC_003262 BX324177.15 misc downstream 4217296 11429393 ~ 11429689 (+)
XLOC_003215 FQ976909.1 non-coding upstream 226646 6946591 ~ 6956379 (+)
XLOC_003212 BX936438.2 non-coding upstream 320657 6862252 ~ 6862368 (+)
XLOC_003227 CR450813.2 non-coding downstream 570417 7782514 ~ 7783314 (+)
XLOC_003228 NA non-coding downstream 613256 7825353 ~ 7826072 (+)
XLOC_003229 NA non-coding downstream 668045 7880142 ~ 7971030 (+)
XLOC_003234 CR847563.1 non-coding downstream 1365957 8578054 ~ 8580557 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000058_00529237_00544012 MEPD, THOP1 coding CI01000058 null 529185 ~ 544027 (+)