XLOC_032218 (slc4a8)


Basic Information

Item Value
gene id XLOC_032218
gene name slc4a8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007117.7
NCBI id CM002890.2
chromosome length 60270059
location 40354424 ~ 40405934 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00062937
gcatttctcacacacacacacaaaaatctaaTTCACTACTCAAAAATGTGCGACTTTGAAACTCAATTGCGCCCCTAAAATAACTTCAGAACACTGTGTTTCACCATAAACGACAGAATTCAATgtaatccacacacacatttttacccTTATGAATTGTACACCCGCTTCAAACTATTTCTGGCGCTTTCCTGCATGTATAGGCGCAAAACCGCATCAATCGAATAACAGCTTCAGCAACAGTCCCAGTTCGAGCTCTGTGATTGGCTGGACAACATATGATGCCGCCACAGTCTGTACCTCTTCCCAAGTCCTGGAGAGCGCGCGCCTAACAGCATTAAAGTAGGCTAAAGACAGGGCGAATGTGCAGCTCAGTTTGAGACTGGATTAAGAGTATCCTACTTAATGCTTCTCTAACCTTATATGCATCAGTTGATCTGGAGTTTCTCAATACGAACTGCTAACCTGAGTCCGGTAGCTATTCTCTCTGTGGAAGCTGTAATCGACGCACCTTTAAAACGGAGTTAACCATGCCAGCCGAAAACAGCGACCAGGAGAGCATGCTGAGCTATCAGAGGCCTGGTGAGGAAGCAGTGGTGGACCATGGAGGCACTAGCTCAGTTCTGAATATCCATTATGAGAAAGAAGAGCTCGAGGGTCACAGGACTCTTTTTGTGGGTGTGCGGATGCCCATGGACAGACCGTCTCACCGTCATCACCGGCCGCACAGTTCCAGACACCGCCGCAGATCTGACAGGATGAGGGCTGGAGGCTCAGCTCAGGACGACGACAACTCAGAAAGTACCCCAGGGGCACACGATACTCCATCCCAGAGGGTTCGGTTTATTCTGGGCACTGAGGAGGACGAGGAGCATGTGGCACATGAACTCTTCACAGAGCTTGATGAAATCTGTGTTAAAGAGGGCAAAGATGCAGAGTGGAAAGAAACTGCAAGGTGGCTAAAGTTCGAAGAAGATGTGGAGGATGGAGGAGAGAGGTGGAGTAAGCCGTATGTAGCCACTCTCTCTCTCCACAGTCTGTTTGAACTGCGCAGCTGCATCATTAATGGGACCGTCCTGCTGGACATGAAGGCAGGCAGCATTGAGGAAATAGCAGATTTGGTGCTTGAAAAACAGGAGACGCCTCATGAACTGGATGACAGTGTGAGAATGAAGGTCCGAGAGGCACTTTTGAAGCGGCATCACCACCAGAATGACAAGAAGAGGAACAACTTGTTGCCTATGGTCAAAACCCTCACAGAAGCCAACAGGAGACATAGTGAAACTCACTTTATGGACAAGACAGGTCTTGCAACATCTCCTCAGCCTCCAACAACAAGCACAGATATAAAGAACGGAGCAACGTCAGAGATTGGCCAGATGGATCTCAGCAAGGTGGACACACATTTCATGAAAAAGATTCCTACTGGAGCAGAAGCTTCCAATGTGCTGGTTGGAGAGCTGGACTTTTTAGAGAGATCCATCGTTGCATTTGTTCGCTTGTCTCCAGCTGTACTGCTGACTGGACTCACTGAAGTTCCCATTCCCACAAGATTCTTGTTCATTTTGCTTGGTCCTGATGGAAAAGCCCAGCAGTACCATGAAATTGGTCGCTCCATGGCCACCATCATGACAGATGAGATTTTCCATGATGTTGCATATAAGGCTAAGGACAGGACGGATTTGTTAGCTGGTATAGATGAGTTTCTTGATCAAGTGACAGTTCTGCCCCCAGGGGAATGGGACCCGTCCATACGCATAGAACCTCCTAAATGTGTCCCATCACAGGAGAAGAGAAAAATGCCGGGAGTGCCGAATGGTACAGCTGTTACTGTTGAGGAAGAGCTACACGCAGAACACCATGGGCCGGAACTGCAGAGAAcaggaagGCTGTTTGGAGGATTGATTTTGGATTTAAAGAGGAAAGCTCCATATTATCTGAGTGACTTTAAAGACGGCCTGACTCTGCAGTGTGTAGCTTCTTTTCTTTTCCTGTACTGTGCCTGTATGTCACCTGTAATCACATTTGGAGGACTTCTGGGAGAGGCAACAGAAGGACAAATTagtgcTATTGAGTCTCTTTTAGGAGCATCTATGACTGGAGTAGCATACTCTCTGTTTGCTGGACAGCCATTAACTATTCTGGGCAGCACTGGACCCGTCCTGGTCTTCGAAAAGATTCTCTTCAAGTTCTGCAAAGACTACGATCTCTCATACCTTTCCCTGCGCACATGTATAGGCCTTTGGACGGCTTTCCTGTGTCTGCTTCTTGTTGCAACGGATGCCAGCTCTTTAGTCTGTTACATCACACGTTTTACAGAGGAAGCTTTTGCTGCGCTCATTTGTCTTATCTTCATTTATGAAGCACTGGAGAAACTTTTCTATCTTGGAGAATTGTACCCGATCAACAGGCATTCCGATCTGGACAAACTCACCCTGGCCTACTGTAGGTGTGCAGAGCCTGATAATCCCAGTAATAAAACACTGGAAGTGTGGAATCAGAGGAACATCACGGCCTCTGCAGTGCCATGGACCAACCTTACTGTAACGgaGTGTTTAGATCTCCAGGGTCAGTTTATTGGACCTTCGTGTGGACATCACGGTCCCTATACCCCTGATGTGCTCTTCTGGTCATCCATCTTGTTCTTTGGTACCTTTTTAATGTCTAGCTTCCTGAAACAGTTTAAGGCTAGCAGATACTTTCCAACACGGGTGCGGTCAATGATCAGTGATTTTGCGGTGTTCCTCACCATTGTTTTCATGGTCCTGATTGATTATATCATTGGAGTTCCATCCCAAAAATTACAAGTCCCCAGCAAGTTCAAGCCTACACGTGATGATCGTGGTTGGGTGATGAACCCAATTGGGCGCAACCCATGGTGGACAGTACTGGCTGCCTTAATACCAGCTCTCCTCTGCACCATTCTCATCTTCATGGACCAACAGATCACTGCAGTCATTATAAACCGCAAAGAGCACAAACTGGTGAAAGGCTGTGGGTACCATTTGGATCTGCTGATGGTCGGGGTGATGTTGGCTGTATGTTCTATGTTGGGATTGCCCTGGTTTGTAGCAGCGACCGTCCTGTCAATATCCCACGTCAACAGCCTGAAGCTGGAGTCTGAAAGCTCAGCCCCTGGAGAACAGCCTCGTTTCCTGGGTATTCAAGAACAGAGGCTGACTGGATTGTTTATCTTTCTGCTCATGGGCTGCTCTGTGTTCATGACTGGATTGTTACAGTTCATTCCCATGCCGGTTCTCTATGGTGTTTTTCTTTATATGGGCGTCTCATCTCTGAAAGGCATTCAGTTGTTTGACCGTCTGAAGCTGTTTGGCATGCCAGCGAAGCATCAGCCAGACTTTATTTATCTCCGCCATGTTCCTCTGAGGAAGGTTCACTTGTTCACTCTGACCCAACTTACCTGCCTTGTGCTGCTCTGGGTCATTAAACATTCCCCTGCCGCAATCGTGTTTCCTATGATGGTCCTGGCATTAGTGTTCATCCGCAAGCTGCTGGACTTCTGTTTTTCCAAACGGGAGCTTAGTTACCTTGATGATCTGATGCCTGAGAATAGAAAGAAGAAGCTGGATGATGATTCCAAGAAAGCAGAGGAGCAGGAATCACAGGAGATGCTGGTGGATGAATCTGGGGAATCGGACAACAAAGACACAGTGCAGATCCCAATGGAGAGCAAACCTCTACACTCTCCTCGAACCCCAGACCCAAGGACTGATCCCTCTGACATTAACATATCTGATGAAATGTCTAAAACTACTGTCTGGAAATCCCTCAATTCCAATAACATGGACACACAACGCGCAAGCACACATAAAAAGGAGGTACCGTGAAGTATCCCTGCAGAAAGAAGAAATTACCTTCTTAGCGACGGTCGTTTGAAATTCGGCTGACTTCGAGAAGCAGCCGCGTGCTAAAAACACACAGATGTTACAGTAGTTCACTTCTTCCCATGTTTCTCACACACATGCGTGTTTATGTATAGCTGTGTGAGATATATTGgtgtctcagtgtgtgtgtgtgtgtgtgaatatgtgcgACATATTCTCCAACCAAATCCAGGTTATTTTCAATGTTTAGTTGGGTTTTAGCAGACATAGGCGTCTCTGTGCTGTGCTGTACTGTACACGTTTTTTGTTTTTCGTTCGTTGTCTGGTTCTAAGTTGTTTAATAGCTGTTTAAATGTTCTCATTTTAACTATATACTTGTAGATAATACTGTATACGTGTGTCAAACCGTCAAAGCAACAAGTTTGTGTGTTTAAGCCAAACATCCGATCAAAATAATAACCTCAGTTGAAACTCTTTTGTGCCAGTATAAATAGCCATTACGTACACTAAACCACCATAAACCAAATCAGTCCTTATCCACTATAGACGGACATGTCTATTTTTATTGCGCGTGCTGTATTCAAACTTGTTAATATTGAGCAATAAAGGCTTATATGGGTTTAGGGATGCTGATGGAGAAGTATGAACTCTATTGCGAGTGTTTTAAACTCCCCTTTCCTTGTATGAACAGGTTAACATTTCCATTATATGCTCCATCCTTTCGGTCTTTCAAGGGTTGAGGGTAAGACTGTTCAGGCTTTCGTTTAAAGACCTTTACGAGTCACCAATCCCAGTAATAAGCCATCTCGTATAGACTACCTCCCCATACTTTTAAAGCTCCCACAATAGATTCTGCACTGAATGAGGTCAAAAAATATGGTTGCGTTTTTAACCTCAGCGAAATAACACTTTATTTACAGTTGCACTTTGTGTAGATATATATACCGatatgattttatattttaaagggaATTATTATATAGAGTATAACAGCGTGATAGTTATTTTAAGTAAAagagttttcttttttatatataaatgtattttaataaaatgagtTGAGCAGATGCAGTAAGACACTGGCTGTTAATGCGAATGGGTTACTgctgtattttttgtttctaacTGGGCCAGTTGTCTGTAAGTCGCGTGTTTCACCTTATTAAACTGCCTTCGGGAGAATGTCATTATATATAATCTGGAATGTCATTTCAGCTTCGGAATGTTGAGGAGTATTGAGCATTTTCCCAGCTTGACATTAAGCTACTGAATTATCTTTATAATCCCCCTCCACGGCTTTCTCGTTTATGGAACTGTTGTCATTGACTTGATTGTACGATGTTATCTTCATGCTGGGATGTGTTCAATGAGAATGTCTTTCACTCCAATAAATTTTAGATTTTATGAATGATGAACCTGTTAAGAgttgtgcatgtgttttttt

Function

symbol description
slc4a8 Predicted to enable sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and transmembrane transport. Predicted to act upstream of or within anion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC4A8 (solute carrier family 4 member 8).

GO:

id name namespace
GO:0051453 regulation of intracellular pH biological_process
GO:0055085 transmembrane transport biological_process
GO:0015701 bicarbonate transport biological_process
GO:0006811 ion transport biological_process
GO:0050801 ion homeostasis biological_process
GO:0006820 anion transport biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005452 inorganic anion exchanger activity molecular_function
GO:0022857 transmembrane transporter activity molecular_function
GO:0008509 anion transmembrane transporter activity molecular_function
GO:0008510 sodium molecular_function

KEGG:

id description
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-131119-88 Predicted to enable sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and transmembrane transport. Predicted to act upstream of or within anion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC4A8 (solute carrier family 4 member 8).

Ensembl:

ensembl_id ENSDARG00000015531

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00062937 True 5289 mRNA 0.44 25 40354424 40405934

Neighbor

gene id symbol gene type direction distance location
XLOC_032217 CU467879.1 coding upstream 304979 40043615 ~ 40049445 (+)
XLOC_032216 NA coding upstream 337287 40004595 ~ 40017137 (+)
XLOC_032215 itpr1a coding upstream 362870 39923052 ~ 39991554 (+)
XLOC_032214 endou coding upstream 441984 39905021 ~ 39912440 (+)
XLOC_032213 NA coding upstream 472197 39874524 ~ 39882227 (+)
XLOC_032219 ghrl coding downstream 32053 40437987 ~ 40439615 (+)
XLOC_032220 BX936393.2 coding downstream 42700 40448634 ~ 40451840 (+)
XLOC_032221 zgc:152986 coding downstream 61628 40467562 ~ 40470521 (+)
XLOC_032222 CU463231.2 coding downstream 69777 40475711 ~ 40481777 (+)
XLOC_032223 fgd5b coding downstream 76396 40482330 ~ 40499799 (+)
XLOC_032210 AL954698.1 non-coding upstream 636866 39700200 ~ 39717558 (+)
XLOC_032209 AL954698.2 non-coding upstream 686852 39666347 ~ 39667572 (+)
XLOC_032225 NA non-coding downstream 139924 40545858 ~ 40551992 (+)
XLOC_032231 NA non-coding downstream 246971 40652905 ~ 40656046 (+)
XLOC_032242 NA non-coding downstream 578663 40984597 ~ 40986135 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000340_09589824_09608037 SLC4A10, SLC4A8 coding CI01000340 null 9589824 ~ 9608605 (+)