XLOC_037954 (ercc1)


Basic Information

Item Value
gene id XLOC_037954
gene name ercc1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007120.7
NCBI id CM002893.2
chromosome length 56459846
location 32674676 ~ 32684008 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00074492
GAATAGTATTAGGGAGCCTCTCAGAGTCGAACGATGTTTCTGTGTGTAACACTTTTGCCTGATTGGTTCGACTGTTTGTTTCGACGCGATGGCGGCAGATGTGATCATGTTTGGTTCCTCTGTGTTGTGCTACCATTGATAACtaacaaaaatggaaaaaaagaagtTTAATATCAATTTGGACGATTCAGCGTTCTCAAAGGACAGAAGTCCGGCGAAGGTGTCTTTGTTCAAATCCAAAAATGATCACGTAGAGGCCTCATCTGTTCCAGCTCCTGGCCAACCACTGTCCTATGCAGAGTTTGTTGTTCAGAACAAACACAAGGGCCATCAGGGAGCCCATGGATCAGAGAAACAAACATCTGCTGCCCAAAGTAGAAATAACGCTCCAGGACAAAGCAGTGCAAACATAGCTGTAATTGAATCAGTTAATACGTCCTCCACAGACTCAGAAAAACCTGAGACTGAACAGCAGGGTCTATCAGAGGGACCTACAGAAGATCAGACCAAAGGGGAAGGTCAGAGTTCAGAGAGTTTTGTGGTTCCTCCTCATCTCTTAGGATCTGGAAACAGTATTATTGTCAGTCCTCGACAGAGGGGCAACCCTATCCTGAAATTTGTGAGAAATGTTCCTTGGGAGTTTGGAGAGGTGGTGCCAGACTATGTTTTAGGAAGGACAACATGTGCACTTTTTCTCAGTGTGCGTTACCATAATCTGAACCCAAACTATGTCCATGAGCGTCTAAAACAGCTGGGCCAGAGTTTCAGTCTCAGAATTCTGCTTGTCCAGGTGGACGTGAAAGACCCTCATCATGCACTGAAAGAGCTTGCACGAATATGCATCATGGCTGACTGTACCCTCATCTTGGCCTGGAGTCCTGAAGAAGCAGGCCGTTATCTTGAAACCTATAAATCCTATGAGAAGAAGCCTGCAGATCTACTTAAAGAGCAAGTAGAGAAAAATTACCTGTCCCaggtTACAGATTGTTTAACCACAGTTAAGTCTGTCAATAAGACTGATGCCATGACTCTTCTGTCTACGTTTTCTTCATTGGAGGGCATCATTAAAGCTTCAAAGGAGGAACTTGTTTTATGTCCAGGACTCGGTCCACAAAAGGCAAGAAGGCTTTATGACGTATTGCATCAGCCCTTCATAAAGACCAAGAAGAAGGAAAGTTGATCATTTTAAGCTGCGTTACAGAAAATGGATTTAGAAAAAGTGTCTGGGACCATCTGAGACCATCAGGCGTGAGAGTTTTTGCTGTTTTTGGCATAAACAGtctctaaatgttatattattagGCTTTGTTTTTCTGTAAgtctaatatttttttgtatatcaTTTTTCATGTGATCAATAAATATCCATAATATTTAGATGTAA

Function

symbol description
ercc1 Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in several diseases, including bone cancer (multiple); carcinoma (multiple); cerebrooculofacioskeletal syndrome 4; hematologic cancer (multiple); and transient cerebral ischemia. Orthologous to human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit).

GO:

id name namespace
GO:0006312 mitotic recombination biological_process
GO:0070914 UV-damage excision repair biological_process
GO:0000710 meiotic mismatch repair biological_process
GO:0006281 DNA repair biological_process
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion biological_process
GO:0070522 ERCC4-ERCC1 complex cellular_component
GO:0000110 nucleotide-excision repair factor 1 complex cellular_component
GO:0005634 nucleus cellular_component
GO:0004519 endonuclease activity molecular_function
GO:0003684 damaged DNA binding molecular_function
GO:0003697 single-stranded DNA binding molecular_function

KEGG:

id description
ko03420 Nucleotide excision repair
ko03460 Fanconi anemia pathway
ko01524 Platinum drug resistance
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-040426-2606 Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in several diseases, including bone cancer (multiple); carcinoma (multiple); cerebrooculofacioskeletal syndrome 4; hematologic cancer (multiple); and transient cerebral ischemia. Orthologous to human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit).

Ensembl:

ensembl_id ENSDARG00000031680

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00074492 True 1384 mRNA 0.42 9 32674676 32684008

Neighbor

gene id symbol gene type direction distance location
XLOC_037953 gzm3.4 coding downstream 2547 32670526 ~ 32672129 (-)
XLOC_037952 gzm3.3 coding downstream 5748 32667169 ~ 32668928 (-)
XLOC_037951 BX571724.2 coding downstream 9214 32662314 ~ 32665462 (-)
XLOC_037950 gzm3.2 coding downstream 11180 32657695 ~ 32663496 (-)
XLOC_037949 gzm3 coding downstream 18020 32654554 ~ 32656656 (-)
XLOC_037955 olig1 coding upstream 44645 32728653 ~ 32730487 (-)
XLOC_037956 BX571724.1 coding upstream 61080 32745088 ~ 32747794 (-)
XLOC_037957 olig2 coding upstream 67420 32751428 ~ 32753535 (-)
XLOC_037958 NA coding upstream 77054 32761062 ~ 32795884 (-)
XLOC_037959 CT030044.1 coding upstream 101409 32785417 ~ 32785537 (-)
XLOC_037946 CR391943.1 non-coding downstream 149305 32525255 ~ 32525371 (-)
XLOC_037945 BX511187.1 non-coding downstream 316011 32355235 ~ 32358665 (-)
XLOC_037942 NA non-coding downstream 395489 32271066 ~ 32279187 (-)
XLOC_037941 NA non-coding downstream 423743 32238733 ~ 32250933 (-)
XLOC_037964 CT030044.2 non-coding upstream 199283 32883291 ~ 32885181 (-)
XLOC_037966 NA non-coding upstream 253821 32937829 ~ 32941228 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000009_02251416_02262823 ERCC1 coding CI01000009 null 2251161 ~ 2262823 (-)