ptgs2b (ptgs2)


Basic Information

Item Value
gene id ptgs2b
gene name ptgs2
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053120.1
NCBI id CM020917.1
chromosome length 41568296
location 13995495 ~ 13999954 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039811906.1
TCAAACTTTCAGCGACATCACAGCgtaggaaaggagagagaaggatAGAACGAGATCCGACGAAGTCTTTGGAGTAGGCTATGAAGACGCTCACGTTTGCGGGTTTGCTCTTGGCGCTGGGGTTTCTTGTCTGCGAAGGGGGTAATCCATGTTGCTCGGAGCCATGCCAGAACAGAGGAGTTTGCACAGCTCTTGGAACAGATAATTACGAGTGTGATTGCACACGCACAGGATATCAGGGACACAACTGCACAACACCTGAATTCCTCACCTGGGTGAAAATATCACTGAAGCCATCGCCCAACACTATCCACTATCTTCTCACCCACTTCAAGGGCTTCTGgaacatcatcaacaacatCTCATTTCTCAGGGATGCCATCATGAGATATGTGCTGACATctCGATCCCATTTGATCGATAGTCCTCCAACTTACAATGCGGATTATGGTTACAAAAGTTGGGAAGCTTATTCCAACCTTTCCTACTATACGCGCACCCTCCCCCCTGTGCCAGAGGATTGCCCAACCCCTTTGGGAGTAGCAGGTAAAAAAGAGCTACCTGATGCTAAGCTGTTGGCTGAGAAGCTTCTAATGAGAAGACAGTTTATCCCGGACCCACAGGGCACCAGCCTGATGTTTGCATTCTTTGCACAGCATTTCACTCACCAGTTCTTCAAATCTGATATGAAGAAAGGGCCTGCTTTTACCTTAGCTAAAGGTCACGGGGTGGACCTCAACCACATTTATGGAAACGACCTGGAGAGGCAACACAAGCTCAGACTCTTTCAGGATGGCAAGCTTAAGTATCAGATCTTGGATGGAGAGGTATACCCCCCAACAGTAAAGGAAGTGGGCGCTGACATGCACTACCCTCCTCATGTTCCCGACTCTCACCGCTTCGCTGTGGGCCATGAGGCATTCGGCCTGGTCCCTGGTCTGATGATGTACGCAACCATCTGGCTACGGGAACATAAccgggtgtgtggtgtgttgaaGGAGGTCCACCCGGACTGGGACGACGAGAGGCTCTTCCAGACCACACGGCTCATTCTAATTGGAGAGACCATCAAGATTGTGATTGAGGACTATGTGCAGCACCTGAGTGGCTATCACTTCAAGCTCAAGTTTGACCCCGAGCTGCTGTTCAACCAGCGCTTCCAGTACCAGAACCGCATTGCATCCGAGTTCAACACCCTGTACCACTGGCACCCCCTGATGCCTGATACTTTCCACATTGAGGAGAAAGATTACAGCTATAAACAGTTTGTCTTCAACACCTCCATAGTGACCGAGCACGGCATCAGCAGCCTTGTGGAGTCGTTTACCAATCAGATTGCTGGACGGGTTGCCGGTGGTCGAAATGTCCCAGGACCTATCGTGTACGTGGCCATTAAGTCCATTGAAAACAGCAGACAAATGCGCTACCAGTCTCTGAACGCCTACAGGAAACGATTCTCCATGAAGCCCTACAGCTCTTTTGAAGACATGACAGGCGAGAAAGAAATGGCCGCAGTGCTTGAGGAGATGTACGGACATGTCGATGCTGTGGAGCTCTACCCGGGTCTGTTGGTGGAGAAACCCAGGTCTAACGCCATCTTTGGGGAGACCATGGTGGAGATGGGGGCTCCTTTCTCCCTCAAGGGCCTAATGGGAAACCCCATCTGTTCCCCGGAGTACTGGAAGCCGAGCACATTCGGAGGCAGCGTGGGCTTCGACATCATCAACACCGCCTCCCTGCAGAGGCTCGTCTGCAATAATGTCCGGGGCCCCTGTCCCGTGGCATCCTTTCATGTGCCCGACGTTAAAGACACGGGGTCCATGATCATCAACTCAAGCACATCCCACTCACGTGGTAGTGATATCAACCCCACagtcattttgaaaaaaaggacTACTGAGCTCtgagcttttttattttataaggttattttttttatgtatgtatttatttattatttattatttattgtattctATTTATAAAATAACTGACATTGTTATGTAATTTTGTATGGACTGTATGATCATGAAAAAagtgtgtggctgtgtttatttattgaaaGATTGttttataagttattgtttgttttgttctcaATACCTGTCGACTGTATGGTTTACAATAAATGGACATGAAACACATTTCTCAGAAA

Function

symbol description
ptgs2 Enables enzyme binding activity and prostaglandin-endoperoxide synthase activity. Involved in cellular response to hypoxia and cyclooxygenase pathway. Located in endoplasmic reticulum; neuron projection; and nuclear membrane. Implicated in several diseases, including arthritis (multiple); avian influenza; cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Biomarker of several diseases, including carcinoma (multiple); functioning pituitary adenoma (multiple); in situ carcinoma (multiple); neurodegenerative disease (multiple); and urinary system cancer (multiple).

NR:

description
prostaglandin G/H synthase 2

GO:

id name namespace
GO:0006979 response to oxidative stress biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004601 peroxidase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG:

id description
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039811906.1 True 2155 mRNA 0.48 10 13995495 13999954

Neighbor

gene id symbol gene type direction distance location
hmcn1 hmcn1 coding upstream 47516 13857034 ~ 13947979 (+)
swt1 LOC102799620 coding upstream 175487 13796094 ~ 13820008 (+)
insl5a LOC104957723,LOC104925860,LOC103372744 coding upstream 579496 13413361 ~ 13415999 (+)
LOC120565922 NA coding upstream 626488 13367294 ~ 13369007 (+)
LOC120565910 NA coding upstream 636370 13356372 ~ 13359125 (+)
pdcb pdc,LOC104921827,LOC102780712 coding downstream 24801 14024755 ~ 14028859 (+)
tprb tpr coding downstream 34303 14034257 ~ 14065550 (+)
fcho1 NA coding downstream 81602 14081556 ~ 14144941 (+)
acsbg2 acsbg2,LOC103367493 coding downstream 173765 14173719 ~ 14203364 (+)
LOC120564948 zap70 coding downstream 345627 14345581 ~ 14361643 (+)
G95239 NA non-coding upstream 24356 13968931 ~ 13971139 (+)
G95236 arpc5,LOC104921830,LOC103367487,LOC103137250 non-coding upstream 40611 13953149 ~ 13954884 (+)
G95179 NA non-coding upstream 160237 13830850 ~ 13835258 (+)
G95177 ivns1abp non-coding upstream 167014 13825457 ~ 13828481 (+)
G95173 ivns1abp non-coding upstream 170226 13822853 ~ 13825269 (+)
G95287 NA non-coding downstream 145051 14145005 ~ 14145318 (+)
G95297 NA non-coding downstream 206385 14206339 ~ 14208562 (+)
G95299 NA non-coding downstream 220617 14220571 ~ 14222594 (+)
LOC120565959 NA non-coding downstream 258331 14258285 ~ 14263886 (+)
G95372 NA non-coding downstream 368968 14368922 ~ 14369226 (+)
LOC120564965 LOC102299696 other upstream 595751 13390823 ~ 13399744 (+)
LOC120564964 LOC102797871,LOC101481459,LOC102301033,LOC106675533,LOC102797273,LOC102300313,LOC102200286 other upstream 612748 13379398 ~ 13382747 (+)
LOC120565776 NA other upstream 653397 13335734 ~ 13342098 (+)
G95046 NA other upstream 775123 13173025 ~ 13220372 (+)
raver2 raver2 other upstream 895050 13005568 ~ 13100445 (+)
G95460 NA other downstream 619404 14619358 ~ 14621413 (+)
LOC120565380 NA other downstream 689428 14689382 ~ 14704353 (+)
dennd1b NA other downstream 810414 14810368 ~ 14923845 (+)
LOC120564959 LOC104946909,LOC103360792,LOC102294988,LOC101486556,LOC102197099 other downstream 1523975 15523929 ~ 15632812 (+)
kcnn1b LOC104945110,LOC103355562 other downstream 2289869 16289823 ~ 16301000 (+)

Expression


Co-expression Network