dll4 (dll4,LOC104955063)


Basic Information

Item Value
gene id dll4
gene name dll4,LOC104955063
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053129.1
NCBI id CM020926.1
chromosome length 36987114
location 15588083 ~ 15597893 (+)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039782510.1
ACGAGTGATGAACATCCGTGGCGCACTGACGCACCAAGTTCAGCACCAAAACAAGCTCTCTGAGCCGCGCGCACACAGCGGAGTGACCGTTGTGGAGTACAGTACGATGCAAGAAGGGGACGCCTGCTGACAGAAAGAAGCACGGCTGTGGATATTGGTCTTCCATCACCTTTGGATAACTTTGAAACGCTTTCTCTGGACGCTTCTGACGCACACCAGCAAGGAGCTACAGGAGAACTCCCTGGGAGTGAAGAAGGATTTATACGAGATTTTCCCCCCCTAATTTGTTTACGTTGGTGTAAATACTTTGGAATAGGAAGGTTTTACTGCTTTATTGGCTGGTGACGCGGCTGCATAGGAGAAGCGAGAAGGATGGCAGCCTGGTTCACCTTTACCATCGCATTCAGCACCACGTTGATATCACAGGTATTTGGATCCGGTGTTTTTGAGCTTGATCTCCACGAATTTAAAAATCACAAAGGTTTGCTGGCAAACGGAAACGCGTGCAAACCCAACTGCAGGACTTATTTTAGAATTTGCTTGAAGAACTATCAGGCTGTGGTCTCGCCAGGTGACTGCATCTTTGGAAGTACAATGACAGCAGTGCTGGGGACAAACTCTTTCAGCGCCAAGGACAGTGGCACTTTACCTAGACCGATTCAGATACCGTTCACCTTTGGATGGCCGGGGTCATTTTCATTAATAATTGAAGCCTGGCATTCACCTTATGGAAGTCTACCTGTAGATAcgaacaacccagagtgtttgaTTAGCTTTATGGCCATCCAAAGACAGCTTGGTGTAGGAACTGATTGGTCTCAGGATACGCAGACTGGAAAGCAGACTGAGCTGAGATATGCTTACCGGTTCATCTGCAACGAAAGTTACTATGGAGAAAGTTGTTCCAAAAAATGTGCGCCCAGGGACGACCGATTTGGCCACTACACCTGCAACCATGACGGGCAGTTATCCTGTCTGCCTGGCTGGAAGGGGAAATACTGCGAAGAACCCATCTGTCTGGAGGGCTGCAGCGAGAGGAACGGAAACTGCTCCAAACCTGGCGAGTGTGTaTGCAGAGATGGCTGGAAGGGTACCTTCTGTGACGAGTGTAGGAAGTACCCGGCCTGTAAGCACGGTACCTGCCAGCTGCCATGGCAGTGTAACTGTCAGGAGGGCTGGGGAGGCCTATTATGTGACCAAGACCTGAACTTCTGCACCCATCACCATCCCTGTGTGAATGGCGCCACCTGTATGAACACAGGACAGGGCAGCTATACGTGTACATGTCTGCCAGGTTTCACAGGGGTCAACTGTGAGCTGGAGATGCAGGAGTGTGACAGCAAACCCTGCAGGAATGGAGGGATATGCACAAATTTGGACAGTGGCTACATGTGCGCATGTCCCCAAGGTTTCGAGGGCTCCCACTGTGAGCACAGCCTGCTGACGTGCGCCGACTCCCCGTGTTTCCACAGCGGCAAATGCTGGGAGAAGGACAATGGCCGCAGCTACATGTGCGAGTGTCCCCGCGGCTACACCGGACTCAACTGCGAGAAGAGAGTGGACAAGTGCACGTCTCTTCCCTGCGCTAATGGTGGTCTGTGTCTGATCCACGGCGGCATGCGCGTGTGTAGCTGCCGTGCAGGATTTACCGGCCAGCGCTGCGAAATTAACATCAACGAGTGTGCCGGTAACCCCTGCCTCAACGGAGGCACCTGCCAAGACCGAATCAACGACTACACCTGCACCTGTCCCGCGGGCTACGGGGGACGCAACTGCGACAGAGCGCTGGATGAGTGTTCCCTTCGCCCATGCCTCAACAGGGGCGTTTGCACTGGGGGCGGCGGGCCAGGCAAACCTCCAGCAACCTGCGCCTGCCCATCAGGCTTCACCGGGCCGCGCTGCGAGTTCTTCGCCGCCGTCACCTCTCCCGTGACCAACGGAGAGATTCAAGACGGCTTCCAGTGGGCGGCCGTTTCTCTGGCTGTGGGGCTGGTGGCGCTGCTGGTGCTGCTGTGTATGGTGGGCCTGGCTTTCAGGCACATCCACAGGCAGGCccaaagagagaggggagacacGGAGACTATGAACAACATCTCCAACGTTCAGAAAGACAACCTGATCCCCGAGTCCCAGCTGAAAAACACCAACCAGAAAATGAGCCTGGAGGTGGACTGTGATTCCGAGAAATCAAACTTTATCCATAAAAACTATATCTTGGACCCATACAACTCTAAATCAAAGGAGTTCAAGGATGAAAAGTCACAAGAGGATAAAAGTCTTATTTATGACAAATGTTTAGAAGACAAAATGCCCTTGAGTAAAATGTACAGTGAAAAGCCAGAGTGTAGGATATCAACGATATGTTCCTCAAGAGACTCCATGTACCAGTCGGTATTTGTTatagcagaggagaggagggagtgCGTCATAGCAACTGAgGTATAAACTGAGGGGTCTGAATGCGAGggtgaaaaaggaaaaagacacAATCGAGGCAGAATAAAATATTCTGGATTGTTTACAAATGCTCAGAAGAGACTGGAGATTGTTTTAGATGTCCACTGCTGCTCTGGAACACTTGAGAACTGAAGAGGGCAGAAACCTCTgctcttcaaaaaaaaaaagaaaacaagaccgAACAGAACTGAGAAACTTTATGTTGACCGAGTGTTTGTATTCAAAACATGTACAGTGAAGGACCTCTCTCAGTTGTGACAACGGTTACACCGACTGGCGAATAGACAATGTGACAAGGTGTGAAGACGGACAGAGCATCGGTGAAATGTTAATTTATAATCTCAGCCATCCTGGACAGCAGAAGGAGGTGAAGGCGGATCTTTGCCCCTCGTATCTGGCCTTTTGTGATAATCATGATGACTTTGACAGCCAACCAATcagtttgaaaagaaaaaaaaaaaaaaaaaggtgcctaAGATTTGACCCCTTCAAATCCCCCTCCCACACACTCACTCCTGCCAGCTTCGCCTGCTATGCAAGACTCCGGGTCGAGACGAGTGAACTCGCCCACTGTCGCAATCCAACCTCACAAACGCTGAGAGTTATGAATGTCTGAAACTAATCTTCAACTGTCAATCACGTGAAAATGACTGGTTGGACTTTTCCATGCAACGGTGAAGATTGTATGCAGTCCAAATTCACTAGAAGCCTTAAAAGAGGGGGTTTGAATGCTAAATTTGTGCCCTTGTCTGTTCTTGGATCATTTGCACTACAAAAGAAAAATCGAGGAAAATAGTTTTTAATCAACAGGGATTTGAAGAGAAAACCACAGGAGCGCAATAGTCAGTGCTGTGCCAGCAAGACCCAAGAGAAAGGAAAAGTTTGCAtagaaaagtgtttttaaaaagttttttttttttatgcaatcCAACTAAGAAAAACAAGGAGAAAAGACTGTCACACCACTGCCTGCCTataatacatttcaaaaatacagaaccaataatgtaatttttttaaatgattatttcCAGAGTTTAATTTAAATATGACACACTGctctttatatgttttataatattattttgtatataatGCATATTTATAAGGACCAAACTTCTGAAGAATAAAACTACCTTGAAAACTG

Function

symbol description
dll4 Predicted to enable Notch binding activity. Acts upstream of or within several processes, including negative regulation of blood vessel endothelial cell migration; vasculature development; and ventral spinal cord interneuron differentiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including atrioventricular canal endocardium; brain; endothelial cell; vasculature; and xanthophore. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human DLL4 (delta like canonical Notch ligand 4).

NR:

description
PREDICTED: delta-like protein 4

GO:

id name namespace
GO:0060854 branching involved in lymph vessel morphogenesis biological_process
GO:0060855 venous endothelial cell migration involved in lymph vessel development biological_process
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway biological_process
GO:0007219 Notch signaling pathway biological_process
GO:0045765 regulation of angiogenesis biological_process
GO:0002040 sprouting angiogenesis biological_process
GO:0060840 artery development biological_process
GO:0043537 negative regulation of blood vessel endothelial cell migration biological_process
GO:0016021 integral component of membrane cellular_component
GO:0005509 calcium ion binding molecular_function

KEGG:

id description
K06051 DLL; delta

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039782510.1 True 3604 mRNA 0.48 11 15588083 15597893

Neighbor

gene id symbol gene type direction distance location
vrtn vrtn coding upstream 287376 15296281 ~ 15300707 (+)
slc25a29 LOC103369942,LOC106518591 coding upstream 301232 15277585 ~ 15286851 (+)
ppp2r5cb LOC103369946,LOC101473650,LOC100694131,LOC104924693 coding upstream 414501 15142703 ~ 15173582 (+)
hsp90aa1.2 LOC107100300,LOC103369947,LOC105919227,LOC103155532,LOC103457915 coding upstream 446690 15135367 ~ 15141393 (+)
mgat2 mgat2 coding upstream 471299 15113170 ~ 15116784 (+)
chac1 chac1 coding downstream 4442 15602335 ~ 15604166 (+)
zfyve1 LOC100698556 coding downstream 82568 15680461 ~ 15687727 (+)
stx7l stx7 coding downstream 132154 15730047 ~ 15738980 (+)
ccn2a ctgf coding downstream 174767 15772660 ~ 15776217 (+)
tmem200a tmem200a coding downstream 255917 15853810 ~ 15877749 (+)
G184481 NA non-coding upstream 94556 15493204 ~ 15493527 (+)
G184474 NA non-coding upstream 109003 15478491 ~ 15479080 (+)
G184465 NA non-coding upstream 265195 15322575 ~ 15322888 (+)
G184463 NA non-coding upstream 265961 15321746 ~ 15322122 (+)
G184461 NA non-coding upstream 267844 15320018 ~ 15320239 (+)
G184509 vps18 non-coding downstream 56953 15654846 ~ 15655520 (+)
G184508 pigh non-coding downstream 81104 15678997 ~ 15680159 (+)
G184521 NA non-coding downstream 179336 15777229 ~ 15780546 (+)
G184526 sel1l,LOC104966051,LOC107585782,LOC107721334 non-coding downstream 199922 15797815 ~ 15798794 (+)
G184561 NA non-coding downstream 291472 15889365 ~ 15889585 (+)
G184458 NA other upstream 269247 15301925 ~ 15318836 (+)
LOC120546207 NA other upstream 294831 15289674 ~ 15293252 (+)
hsp90aa1.1 LOC103369948 other upstream 453223 15129476 ~ 15134860 (+)
G184258 NA other upstream 1058713 14525136 ~ 14529370 (+)
LOC120546619 LOC103359912,LOC102080314 other upstream 1163219 14393440 ~ 14424864 (+)
rhov rhov,LOC102778135,LOC100699098,LOC101469787,LOC102306362,LOC107602886 other downstream 62680 15660573 ~ 15663661 (+)
dpf3 LOC100693327,LOC101467145,LOC103380755,LOC104966071,LOC102779461 other downstream 97051 15694944 ~ 15719632 (+)
LOC120546249 NA other downstream 316693 15914586 ~ 15968123 (+)
nkain2 nkain2 other downstream 650201 16248094 ~ 16391851 (+)
cenpw NA other downstream 781586 16379479 ~ 16381856 (+)

Expression


Co-expression Network