dhfr (dhfr,LOC103371587)


Basic Information

Item Value
gene id dhfr
gene name dhfr,LOC103371587
gene type coding
species eurasian perch (Perca fluviatilis)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_053116.1
NCBI id CM020913.1
chromosome length 44101041
location 13236216 ~ 13237110 (-)
genome version GENO_Pfluv_1.0_2020_eurasian_perch_Genome

Sequence

>XM_039799633.1
ATGCGCGGGAAAAGTTCTCGTAATAATACTTCAATGGGGCAAAGAGCAACATTTTTTTAGCCCTGTCACTTGCTGTGAGCGTAAAACTTGAAGAACATCATTCCCACGTGCTTCTCTAACATCTGTCGGCAGGAAGCTGCGGCGATTATACCAGCATAACGTTAATAACGTCAGCTGTCCAGTCTCTTAACGATGTCCCGAATTCTGAACGGTATCGTGGCGGTATGCCCTGACCTGGGTATCGGAAACAATGGAAATCTGCCCTGGCATCCCGTTAGACTCAATAACGAATTCAAACATTTCCGAACGATGACTGCGACGCCATCGGTGAACGGCAAGCAGAATGTGGTGATCATGGGCAGGAAAACATGGTTTTCCATCCCAGAAAAGAACAGACCTCTGAACAACCGAATTAACATCGTCCTGAGCAGGGAGTGCAAATCGCCCCCCGCGGGAGCACACCACCTGGCGCGAGACTTCAGCTCGGCTCTCAGGCTGGTCGACACGGAGCTGGCACAGCAGGCTGACACCGTCTGGGTCATTGGGGGCAGCTCTCTCTACAAGGAGATGATGGAGAGTCCGGGAACCAGGAGGCTATTCGTCACACGGATCCTGAAGCAGTTTGAGTGTGACACGTTCCTCCCTGAAATCAGTCCGGACAAATATCGTCTACTGCCAGAGTTTCCAGGAGTGCCGCAAGAGCTACAGGAGGAGAACGGTATCCAGTACAGATTTGAAGTCTATGAGAGCATCCAGCAATGAAGTGACagtgataagaaaaaaaattaaaaccagaACAATGCAAAAATTGTAAAGAAAAAATCTGAAATTATCAACTGAAGAAAAACAATTTTGTGGATTTTCTATTAAAACTGCAAGTGTGAATGAAATACAA

Function

symbol description
dhfr Enables dihydrofolate reductase activity. Acts upstream of or within folic acid metabolic process; heart contraction; and heart development. Predicted to be active in mitochondrion. Is expressed in several structures, including anterior neural tube; hematopoietic system; immature eye; nervous system; and neural plate. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human DHFR (dihydrofolate reductase) and DHFR2 (dihydrofolate reductase 2).

NR:

description
dihydrofolate reductase

GO:

id name namespace
GO:0046655 folic acid metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0009165 nucleotide biosynthetic process biological_process
GO:0006545 glycine biosynthetic process biological_process
GO:0001947 heart looping biological_process
GO:0060047 heart contraction biological_process
GO:0050661 NADP binding molecular_function
GO:0004146 dihydrofolate reductase activity molecular_function

KEGG:

id description
K00287 DHFR, folA; dihydrofolate reductase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_039799633.1 True 895 mRNA 0.47 1 13236216 13237110

Neighbor

gene id symbol gene type direction distance location
ccdc187 LOC103354907 coding downstream 321133 12896793 ~ 12915083 (-)
apex2 apex2 coding downstream 491894 12740741 ~ 12744322 (-)
LOC120559801 slc38a5,LOC104951559 coding downstream 496392 12729392 ~ 12739824 (-)
wasb was coding downstream 507447 12722054 ~ 12728769 (-)
LOC120558430 NA coding downstream 539159 12685286 ~ 12697057 (-)
LOC120558584 cdc42,LOC100697482,LOC101164400,LOC101073733,LOC107083933,LOC103465423,LOC100691174 coding upstream 6064 13243174 ~ 13249562 (-)
mfsd4ab mfsd4a,LOC105928558 coding upstream 22215 13259325 ~ 13262798 (-)
LOC120559884 NA coding upstream 55404 13292514 ~ 13299992 (-)
LOC120559881 NA coding upstream 70478 13307588 ~ 13328250 (-)
LOC120559526 NA coding upstream 102383 13339493 ~ 13343953 (-)
G49407 NA non-coding downstream 311888 12921001 ~ 12924328 (-)
G49384 NA non-coding downstream 397084 12837520 ~ 12839132 (-)
G49374 nt5dc2,LOC102799881 non-coding downstream 456896 12775917 ~ 12779320 (-)
G49372 NA non-coding downstream 464797 12768820 ~ 12771419 (-)
G49307 NA non-coding downstream 532111 12700429 ~ 12704105 (-)
G49447 LOC104955234 non-coding upstream 44877 13281987 ~ 13284250 (-)
LOC120558463 NA non-coding upstream 118007 13355117 ~ 13357805 (-)
LOC120558462 NA non-coding upstream 129153 13366263 ~ 13368373 (-)
LOC120558464 NA non-coding upstream 139517 13376627 ~ 13378863 (-)
G49514 NA non-coding upstream 195409 13432519 ~ 13433095 (-)
camta1a LOC103354943,LOC102299287,LOC102779653,LOC102211199,LOC106922242,LOC104961361,LOC107390471,LOC108232047,LOC103144055 other downstream 14878 12924458 ~ 13221338 (-)
prickle3 prickle3,LOC102790576 other downstream 796307 12415603 ~ 12439909 (-)
fkbp1aa LOC100692950,LOC107391264,LOC103354614,LOC101168621 other downstream 844539 12388981 ~ 12391677 (-)
ppdpfa LOC104933328,LOC101073585 other downstream 1013188 12220734 ~ 12223028 (-)
dnmt3ba NA other downstream 1067007 12147414 ~ 12169209 (-)
LOC120558587 NA other upstream 13876 13250986 ~ 13253608 (-)
LOC120558437 NA other upstream 71250 13308360 ~ 13312729 (-)
LOC120558461 NA other upstream 169675 13406785 ~ 13413178 (-)
zgc:66479 NA other upstream 510293 13747403 ~ 13753866 (-)
smim29 LOC104942556,LOC104932788,LOC105416285,LOC106572343,LOC105022745 other upstream 802625 14039735 ~ 14125823 (-)

Expression


Co-expression Network