| Item | Value |
|---|---|
| gene id | lef1 |
| gene name | lef1,LOC103361279 |
| gene type | misc |
| species | striped catfish (Pangasianodon hypophthalmus) |
| category of species | economic fish |
| Item | Value |
|---|---|
| chromosome id | NC_047597.1 |
| NCBI id | CM018543.1 |
| chromosome length | 33776708 |
| location | 7161474 ~ 7204699 (-) |
| genome version | GENO_Phyp_1.0_2019_striped_catfish_Genome |
| symbol | description |
|---|---|
| lef1 | Enables sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; fin development; and fin regeneration. Predicted to be located in nucleus. Predicted to be part of beta-catenin-TCF complex. Is expressed in several structures, including midbrain hindbrain boundary neural rod; nervous system; neural crest; pleuroperitoneal region; and trunk. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human LEF1 (lymphoid enhancer binding factor 1). |
| description |
|---|
| lymphoid enhancer-binding factor 1 isoform X3 |
| id | name | namespace |
|---|---|---|
| GO:0060070 | canonical Wnt signaling pathway | biological_process |
| GO:0022407 | regulation of cell-cell adhesion | biological_process |
| GO:0048747 | muscle fiber development | biological_process |
| GO:0021542 | dentate gyrus development | biological_process |
| GO:0010628 | positive regulation of gene expression | biological_process |
| GO:0042100 | B cell proliferation | biological_process |
| GO:0061153 | trachea gland development | biological_process |
| GO:0001755 | neural crest cell migration | biological_process |
| GO:0001756 | somitogenesis | biological_process |
| GO:0071864 | positive regulation of cell proliferation in bone marrow | biological_process |
| GO:0071866 | negative regulation of apoptotic process in bone marrow cell | biological_process |
| GO:0002040 | sprouting angiogenesis | biological_process |
| GO:0021861 | forebrain radial glial cell differentiation | biological_process |
| GO:0021873 | forebrain neuroblast division | biological_process |
| GO:0071895 | odontoblast differentiation | biological_process |
| GO:0021879 | forebrain neuron differentiation | biological_process |
| GO:0030509 | BMP signaling pathway | biological_process |
| GO:0046632 | alpha-beta T cell differentiation | biological_process |
| GO:0030223 | neutrophil differentiation | biological_process |
| GO:0001837 | epithelial to mesenchymal transition | biological_process |
| GO:0016202 | regulation of striated muscle tissue development | biological_process |
| GO:0032696 | negative regulation of interleukin-13 production | biological_process |
| GO:1900052 | regulation of retinoic acid biosynthetic process | biological_process |
| GO:0032713 | negative regulation of interleukin-4 production | biological_process |
| GO:0032714 | negative regulation of interleukin-5 production | biological_process |
| GO:0001569 | branching involved in blood vessel morphogenesis | biological_process |
| GO:0031101 | fin regeneration | biological_process |
| GO:0021943 | formation of radial glial scaffolds | biological_process |
| GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process |
| GO:0050769 | positive regulation of neurogenesis | biological_process |
| GO:0048341 | paraxial mesoderm formation | biological_process |
| GO:0048922 | posterior lateral line neuromast deposition | biological_process |
| GO:0060784 | regulation of cell proliferation involved in tissue homeostasis | biological_process |
| GO:0021979 | hypothalamus cell differentiation | biological_process |
| GO:0030879 | mammary gland development | biological_process |
| GO:0001649 | osteoblast differentiation | biological_process |
| GO:0048069 | eye pigmentation | biological_process |
| GO:0033334 | fin morphogenesis | biological_process |
| GO:0030326 | embryonic limb morphogenesis | biological_process |
| GO:0033336 | caudal fin development | biological_process |
| GO:0033339 | pectoral fin development | biological_process |
| GO:0060561 | apoptotic process involved in morphogenesis | biological_process |
| GO:0060325 | face morphogenesis | biological_process |
| GO:0016055 | Wnt signaling pathway | biological_process |
| GO:0005667 | transcription regulator complex | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0043565 | sequence-specific DNA binding | molecular_function |
| GO:0070016 | armadillo repeat domain binding | molecular_function |
| GO:0003682 | chromatin binding | molecular_function |
| GO:0008013 | beta-catenin binding | molecular_function |
| GO:0008301 | DNA binding, bending | molecular_function |
| GO:0045295 | gamma-catenin binding | molecular_function |
| GO:0030331 | estrogen receptor binding | molecular_function |
| id | description |
|---|---|
| K04492 | LEF1; lymphoid enhancer-binding factor 1 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| XM_026933026.2 | True | 3050 | mRNA | 0.45 | 11 | 7161474 | 7204699 |
| XM_026933034.2 | False | 2519 | mRNA | 0.45 | 11 | 7161474 | 7204151 |
| XM_026933042.2 | False | 3009 | mRNA | 0.44 | 10 | 7161474 | 7204699 |
| XR_004577908.1 | False | 2583 | misc_RNA | 0.46 | 12 | 7161474 | 7204151 |
| XR_004577909.1 | False | 2600 | misc_RNA | 0.46 | 12 | 7161474 | 7204151 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| gstcd | gstcd,LOC107095855,LOC106602269 | coding | downstream | 41854 | 7017457 ~ 7119620 (-) |
| npnta | npnt | coding | downstream | 155440 | 6942697 ~ 7006034 (-) |
| aimp1a | aimp1 | coding | downstream | 316983 | 6824909 ~ 6844491 (-) |
| pkd2 | pkd2,LOC107583176,LOC107684281,LOC107706826,LOC107675808 | coding | downstream | 445211 | 6700324 ~ 6716263 (-) |
| LOC117596878 | LOC108263069 | coding | downstream | 501483 | 6643933 ~ 6659991 (-) |
| LOC113538928 | LOC108261848,LOC108262968 | coding | upstream | 114400 | 7319099 ~ 7325006 (-) |
| LOC113542008 | LOC108261848,LOC108262968 | coding | upstream | 120675 | 7325374 ~ 7338431 (-) |
| si:ch211-113e8.3 | LOC108262753,LOC105903925 | coding | upstream | 157216 | 7361915 ~ 7384163 (-) |
| clgn | clgn,LOC107674239,LOC107737082,LOC107671330,LOC107556507 | coding | upstream | 425470 | 7630169 ~ 7646075 (-) |
| zgc:153642 | NA | coding | upstream | 497953 | 7702652 ~ 7715901 (-) |
| LOC117596848 | NA | non-coding | downstream | 19172 | 7141099 ~ 7142302 (-) |
| G42008 | NA | non-coding | downstream | 144069 | 7016765 ~ 7017405 (-) |
| G41944 | NA | non-coding | downstream | 149168 | 7012093 ~ 7012306 (-) |
| G41938 | NA | non-coding | downstream | 220016 | 6941240 ~ 6941458 (-) |
| G41809 | dkk2,LOC107594451,LOC107684280 | non-coding | downstream | 363854 | 6794579 ~ 6797620 (-) |
| G42173 | NA | non-coding | upstream | 108969 | 7313668 ~ 7315596 (-) |
| G42179 | NA | non-coding | upstream | 137768 | 7342467 ~ 7342681 (-) |
| G42315 | NA | non-coding | upstream | 231743 | 7436442 ~ 7438889 (-) |
| G42361 | NA | non-coding | upstream | 363672 | 7568371 ~ 7652220 (-) |
| G42391 | NA | non-coding | upstream | 466888 | 7671587 ~ 7672864 (-) |
| gab1 | gab1 | other | downstream | 1341961 | 5756017 ~ 5819513 (-) |
| lsm6 | lsm6 | other | downstream | 1933507 | 5203706 ~ 5227967 (-) |
| tmem184c | tmem184c,LOC107742544,LOC107670728,LOC107654969 | other | downstream | 2255235 | 4893902 ~ 4906239 (-) |
| dclk2a | LOC108263760,LOC108429594 | other | downstream | 2552024 | 4545139 ~ 4609450 (-) |
| trnah-gug_3 | NA | other | downstream | 4126921 | 3034482 ~ 3034553 (-) |
| maml3 | maml3 | other | upstream | 234205 | 7438904 ~ 7589663 (-) |
| rgs12b | rgs12,rgs12b,LOC108443250,LOC107749922,LOC107679871,LOC107551217 | other | upstream | 929942 | 8134641 ~ 8216551 (-) |
| trnam-cau_4 | NA | other | upstream | 1265287 | 8469986 ~ 8470057 (-) |
| trnae-cuc_7 | NA | other | upstream | 1265659 | 8470358 ~ 8470429 (-) |
| LOC113539440 | NA | other | upstream | 1278604 | 8483303 ~ 8492983 (-) |