mitfa (mitf,LOC108424034)


Basic Information

Item Value
gene id mitfa
gene name mitf,LOC108424034
gene type misc
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047596.1
NCBI id CM018542.1
chromosome length 35203048
location 8260485 ~ 8265229 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026921537.2
CaaattttcttcctctctcttttatattttcattgttgtaTCTTTGAGTGCATTGAATGCAGCCGGTCCAGAAGCCTGAACGCGCCTGACTTCCTTTATTTGGTCACTATAACCTGGCTGAGTGCACGAACTGACTACTTACTGAGGTCTCTGTGTTGATCTGTTGCGCATAACAATATGTTGGACATGCTTGAGTACAGTCATTACCAGGTACAGACTCATTTGGAGAGCCCTAATAAGTACCACCTCCAGCAGAGTCCAAGGCAGCAGGTGAAGCACTATCTGCCCAGCACGCTTGGGGCTAAGCTCAGCCCTCCGTTAAACAGCCAGAATCCGGAGCACGGCATGCCCCCCGGCCCCGGAGCCAGCGCCCCCAACAGCCCCATGGCCCTGCTCACCCTCAGCAACAACTGCGAGAAAGAGATGGACGACGTAATTGAAGACATTATCAGTTTGGAGTCAAGCTATAATGATGATATCCTTGGATTAATGGACGCAGGACTTCAAATACCAAATACAATCCCAGTTTCTGCAAATCTCTTGGACATCTATAGTAATCATACACTTCCTCCAGCTGGAGTCACCATTGGGAATTCCTGCCCATCTAGTTTACCCAATGTGAAAAGGGAATTCTCAGCTCCTGACATGATGCACGTGGACCAACCTGGACCATGTGGCAAGTTTGACTCTTATCAGAGGCCCGAAGGCCTTCCAGTAGaagcaGAAGTCAGAGCTTTGGCAAAAGAGAGGCAAAAGAAGGACAACCACAACCTAAttGAACGGAGACGGCGCTTTAACATAAATGACAGAATTAAAGAACTTGGGACGTTAATTCCCAAATCTAATGATCCAGATATGAGGTGGAATAAAGGAACTATTCTGAAGGCCTCAGTGGACTACATCAGGAAACtacagagagagcagcagagagCAAAAGAGCTGGAGAGCAGGCAGAAGAGACTCGAGCACACCAACAGACACCTCCTGCTTCGCATTCAGGAGCTGGAGATGCAGGCTCGTGCTCATGGCCTGGCTGTAGGAGGCTCCTCAACGCTCTGCTCCACTGAGTTGGTGGCTTGCGCCATCAAGGAAGAACCCATCAGCTACACAAGCTGCTCATCCGAGCTGTACACTCGTCCACACCTCCCCAGCCCGGATCATTCTCGGCCCACCACTCTGGACCTCAACAATGGCACCATTAGCTACAGTGACAGCACCACCGAGGAAGCAGAGGCAGGGCTTTATGCAAGCCGCAAAGAACCCACAACCAAGCTAGACGACATGTTTCTGGAGAACACACTGTCACCAGTGGGCACCAGTAACCTGCTGCTCTCCTCAGGTTCTCCCACACACTCCAATGACAGCAGCAGACGAAGCAGCACGAGCACAGAGGAGCAGGACAAGGGCTGTTAGCACTGCTAATGAACTTTTAATAACTCTTTATGACTGTTTTTGTTTAGGATTGTTTTCGTTGTTGGGTTGATTACAGTAGTAGTGTATTCAAAGATGTTTCTGTGCACTGCTAAAGATATGCAAGGATTTGGAACACCACTGGGATTTTTGGGATCTTTTGAAATGTGATTTGTTTCCAGTACATTAATTCTGTTACATCTAGTGTAACAGATGTGATTCCATTTTGCCCATGATTTttgatatatattatttatattaaaaaaaaaaaaagacaagagaaACATTAGTTATGTCATGATGCCTCATCCTAGTTTATACttgcattatactgtatattattagcATATCTGTAATCTGTCatttaatcagaagtaaaatgaGATAATTCTGAAGTTATTGCTTTTAGTGCCATTATAACTGCCAAAGTTTAAAGTTCTCACAAAATTTCTTTGGTgtaaattctaataataataataataataataataataataataataataataataataataccccTTTACTCAGATTTGGTGTTAAATTtgaattatatactgtatttatggtAAATTAAGATTCTTAGTACCAAATTTCACAAAAATTAGTAACTCCTAAAGGATATAGATGATAACTATAgactaacaataataaatagGTTAAGAGTTAACAGGGTTTTCTTCAATCTGTAGTGTATCATTTAATTATCCACCAGAATATATAcgtaatttctttttttcaattagTCATCAGAAAGAACATAAATAAGTACATTATAAACTGAAAATGGACAGAAATAATGGTTATTCAAATTTAGTTATCCATATAGTTATACAGTATTCACTATATTGTATTCTCTATGTGCTTtttctaatatattttattagaaaagTGGAAAGTTCACCTTCTGATTACTCCCTATGGTATATTTGTTTACATGGTAAATATATAAGTTTGGAATTTGAAGTATTTGCtcattattaatgtattcaGTATTAACTtgttatatgattttatatactgtaactACAGAATATTTGTTTTCTCAATTTCTTGGCAGTACACGCTTAGAAAAAAGCGGTTCTTTGAATATGAAAAAATTCTTAGCTTCTTAAAATGGGTTTATTTTGGAACCGTTCCTGATcgggaaacactctgttgtaggtttctacttagaacctttaagggttccctcaCAAGCACAACCagagaacccttaagggttctattTGACCCTTTTCTAATAGtgttatatagatatatagtaGGATATATAGATATGAATCATTAGTTCACAACTGAGAGACCTTGAATGAAGTGCCTTTAACTGAAGaaata
>XM_026921551.2
CaaattttcttcctctctcttttatattttcattgttgtaTCTTTGAGTGCATTGAATGCAGCCGGTCCAGAAGCCTGAACGCGCCTGACTTCCTTTATTTGGTCACTATAACCTGGCTGAGTGCACGAACTGACTACTTACTGAGGTCTCTGTGTTGATCTGTTGCGCATAACAATATGTTGGACATGCTTGAGTACAGTCATTACCAGGTACAGACTCATTTGGAGAGCCCTAATAAGTACCACCTCCAGCAGAGTCCAAGGCAGCAGGTGAAGCACTATCTGCCCAGCACGCTTGGGGCTAAGCTCAGCCCTCCGTTAAACAGCCAGAATCCGGAGCACGGCATGCCCCCCGGCCCCGGAGCCAGCGCCCCCAACAGCCCCATGGCCCTGCTCACCCTCAGCAACAACTGCGAGAAAGAGATGGACGACGTAATTGAAGACATTATCAGTTTGGAGTCAAGCTATAATGATGATATCCTTGGATTAATGGACGCAGGACTTCAAATACCAAATACAATCCCAGTTTCTGCAAATCTCTTGGACATCTATAGTAATCATACACTTCCTCCAGCTGGAGTCACCATTGGGAATTCCTGCCCATCTAGTTTACCCAATGTGAAAAGGGAATTCTCAGaagcaGAAGTCAGAGCTTTGGCAAAAGAGAGGCAAAAGAAGGACAACCACAACCTAAttGAACGGAGACGGCGCTTTAACATAAATGACAGAATTAAAGAACTTGGGACGTTAATTCCCAAATCTAATGATCCAGATATGAGGTGGAATAAAGGAACTATTCTGAAGGCCTCAGTGGACTACATCAGGAAACtacagagagagcagcagagagCAAAAGAGCTGGAGAGCAGGCAGAAGAGACTCGAGCACACCAACAGACACCTCCTGCTTCGCATTCAGGAGCTGGAGATGCAGGCTCGTGCTCATGGCCTGGCTGTAGGAGGCTCCTCAACGCTCTGCTCCACTGAGTTGGTGGCTTGCGCCATCAAGGAAGAACCCATCAGCTACACAAGCTGCTCATCCGAGCTGTACACTCGTCCACACCTCCCCAGCCCGGATCATTCTCGGCCCACCACTCTGGACCTCAACAATGGCACCATTAGCTACAGTGACAGCACCACCGAGGAAGCAGAGGCAGGGCTTTATGCAAGCCGCAAAGAACCCACAACCAAGCTAGACGACATGTTTCTGGAGAACACACTGTCACCAGTGGGCACCAGTAACCTGCTGCTCTCCTCAGGTTCTCCCACACACTCCAATGACAGCAGCAGACGAAGCAGCACGAGCACAGAGGAGCAGGACAAGGGCTGTTAGCACTGCTAATGAACTTTTAATAACTCTTTATGACTGTTTTTGTTTAGGATTGTTTTCGTTGTTGGGTTGATTACAGTAGTAGTGTATTCAAAGATGTTTCTGTGCACTGCTAAAGATATGCAAGGATTTGGAACACCACTGGGATTTTTGGGATCTTTTGAAATGTGATTTGTTTCCAGTACATTAATTCTGTTACATCTAGTGTAACAGATGTGATTCCATTTTGCCCATGATTTttgatatatattatttatattaaaaaaaaaaaaagacaagagaaACATTAGTTATGTCATGATGCCTCATCCTAGTTTATACttgcattatactgtatattattagcATATCTGTAATCTGTCatttaatcagaagtaaaatgaGATAATTCTGAAGTTATTGCTTTTAGTGCCATTATAACTGCCAAAGTTTAAAGTTCTCACAAAATTTCTTTGGTgtaaattctaataataataataataataataataataataataataataataataataataccccTTTACTCAGATTTGGTGTTAAATTtgaattatatactgtatttatggtAAATTAAGATTCTTAGTACCAAATTTCACAAAAATTAGTAACTCCTAAAGGATATAGATGATAACTATAgactaacaataataaatagGTTAAGAGTTAACAGGGTTTTCTTCAATCTGTAGTGTATCATTTAATTATCCACCAGAATATATAcgtaatttctttttttcaattagTCATCAGAAAGAACATAAATAAGTACATTATAAACTGAAAATGGACAGAAATAATGGTTATTCAAATTTAGTTATCCATATAGTTATACAGTATTCACTATATTGTATTCTCTATGTGCTTtttctaatatattttattagaaaagTGGAAAGTTCACCTTCTGATTACTCCCTATGGTATATTTGTTTACATGGTAAATATATAAGTTTGGAATTTGAAGTATTTGCtcattattaatgtattcaGTATTAACTtgttatatgattttatatactgtaactACAGAATATTTGTTTTCTCAATTTCTTGGCAGTACACGCTTAGAAAAAAGCGGTTCTTTGAATATGAAAAAATTCTTAGCTTCTTAAAATGGGTTTATTTTGGAACCGTTCCTGATcgggaaacactctgttgtaggtttctacttagaacctttaagggttccctcaCAAGCACAACCagagaacccttaagggttctattTGACCCTTTTCTAATAGtgttatatagatatatagtaGGATATATAGATATGAATCATTAGTTCACAACTGAGAGACCTTGAATGAAGTGCCTTTAACTGAAGaaata
>XR_004580309.1
CaaattttcttcctctctcttttatattttcattgttgtaTCTTTGAGTGCATTGAATGCAGCCGGTCCAGAAGCCTGAACGCGCCTGACTTCCTTTATTTGGTCACTATAACCTGGCTGAGTGCACGAACTGACTACTTACTGAGGTCTCTGTGTTGATCTGTTGCGCATAACAATATGTTGGACATGCTTGAGTACAGTCATTACCAGGTACAGACTCATTTGGAGAGCCCTAATAAGTACCACCTCCAGCAGAGTCCAAGGCAGCAGGTGAAGCACTATCTGCCCAGCACGCTTGGGGCTAAGCTCAGCCCTCCGTTAAACAGCCAGAATCCGGAGCACGGCATGCCCCCCGGCCCCGGAGCCAGCGCCCCCAACAGCCCCATGGCCCTGCTCACCCTCAGCAACAACTGCGAGAAAGAGATGGACGACGTAATTGAAGACATTATCAGTTTGGAGTCAAGCTATAATGATGATATCCTTGGATTAATGGACGCAGGACTTCAAATACCAAATACAATCCCAGTTTCTGCAAATCTCTTGGACATCTATAGTAATCATACACTTCCTCCAGCTGGAGTCACCATTGGGAATTCCTGCCCATCTAGTTTACCCAATGTGAAAAGGGAATTCTCAGCTCCTGACATGATGCACGTGGACCAACCTGGACCATGTGGCAAGTTTGACTCTTATCAGAGGCCCGAAGGCCTTCCAaagcaGAAGTCAGAGCTTTGGCAAAAGAGAGGCAAAAGAAGGACAACCACAACCTAAttGAACGGAGACGGCGCTTTAACATAAATGACAGAATTAAAGAACTTGGGACGTTAATTCCCAAATCTAATGATCCAGATATGAGGTGGAATAAAGGAACTATTCTGAAGGCCTCAGTGGACT

Function

symbol description
mitf Enables DNA-binding transcription activator activity, RNA polymerase II-specific and E-box binding activity. Involved in several processes, including negative regulation of cell migration; positive regulation of gene expression; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Part of protein-containing complex. Implicated in Tietz syndrome; Tietze's syndrome; Waardenburg syndrome type 2A; Waardenburg's syndrome; and familial melanoma. Biomarker of melanoma.

NR:

description
microphthalmia-associated transcription factor-like isoform X1

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0005654 nucleoplasm cellular_component
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
K09455 MITF; microphthalmia-associated transcription factor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026921537.2 True 2748 mRNA 0.39 9 8260485 8265229
XM_026921551.2 False 2667 mRNA 0.39 8 8260485 8265229
XR_004580309.1 False 894 misc_RNA 0.47 8 8262619 8265229

Neighbor

gene id symbol gene type direction distance location
gpr27 gpr27 coding downstream 266862 7991214 ~ 7993623 (-)
gxylt2 gxylt2,LOC107666964,LOC106565732 coding downstream 438427 7788563 ~ 7822058 (-)
ppp4r2b ppp4r2,LOC102785172,LOC107667031 coding downstream 474036 7778190 ~ 7786449 (-)
chl1b chl1,LOC100380675 coding downstream 889966 7282007 ~ 7370519 (-)
LOC113529215 LOC108271629,LOC108435695 coding downstream 1067344 7066318 ~ 7193141 (-)
gnat1 LOC108271583,LOC108424115,LOC102793896,LOC108231337 coding upstream 304118 8569347 ~ 8574762 (-)
inka1b LOC108271512,LOC108415076,LOC107723929,LOC107587643,LOC107708110,LOC107595459,LOC107666006 coding upstream 584753 8849982 ~ 8853110 (-)
gnai2b LOC108271854,LOC107587570,LOC103137272,LOC107723915,LOC103360398 coding upstream 595143 8860372 ~ 8915086 (-)
slc38a3b slc38a3,slc38a3b,LOC108271853,LOC108411719,LOC107666102,LOC107723914 coding upstream 656895 8922124 ~ 8953564 (-)
rbm5 rbm5,LOC108271979,LOC108433690,LOC107696464 coding upstream 707940 8973169 ~ 8982021 (-)
G23499 NA non-coding downstream 170867 8087767 ~ 8089618 (-)
G23422 rybp,LOC108272260,LOC107599415,LOC107732045,LOC106511513,LOC107680715 non-coding downstream 331769 7927107 ~ 7928716 (-)
G23424 NA non-coding downstream 335054 7925165 ~ 7925431 (-)
G23428 NA non-coding downstream 343893 7915609 ~ 7916592 (-)
G23427 NA non-coding downstream 345691 7913696 ~ 7914794 (-)
G23605 NA non-coding upstream 99071 8364300 ~ 8365123 (-)
G23610 NA non-coding upstream 152145 8417374 ~ 8417993 (-)
G23615 NA non-coding upstream 161892 8427121 ~ 8427325 (-)
G23617 NA non-coding upstream 164552 8429781 ~ 8430093 (-)
G23619 NA non-coding upstream 165251 8430480 ~ 8430694 (-)
G22591 NA other downstream 1780474 6479402 ~ 6480011 (-)
LOC113546630 cox6c,LOC107100236,LOC105920077,LOC108272167,LOC101061984,LOC105901862,LOC107666035 other downstream 2051819 6205284 ~ 6208666 (-)
LOC117596222 NA other downstream 2183608 6074035 ~ 6076877 (-)
blcap blcap,bc10 other downstream 2295302 5956639 ~ 5965183 (-)
romo1 romo1,LOC102788570 other downstream 2724425 5532037 ~ 5536060 (-)
arl6ip5a arl6ip5,LOC107680705,LOC107750278,LOC107599422,LOC108424109,LOC107667022,LOC107713508,LOC107584514 other upstream 78395 8343624 ~ 8351694 (-)
tcta glyctk,tcta,LOC106582802,LOC106565977 other upstream 214145 8479374 ~ 8484181 (-)
tusc2a LOC108271982,LOC108433681,LOC104930950,LOC107595412,LOC107724521 other upstream 1170277 9435506 ~ 9441845 (-)
tnnt2b tnnt2,LOC108441587,LOC107696448,LOC107595452 other upstream 1450287 9715516 ~ 9726051 (-)
G24516 NA other upstream 1598138 9863367 ~ 9868278 (-)

Expression


Co-expression Network