grhl2b (grhl2,grhl2b,LOC107748368,LOC107672862,LOC107550099,LOC107552317,LOC107738316,LOC107698657)


Basic Information

Item Value
gene id grhl2b
gene name grhl2,grhl2b,LOC107748368,LOC107672862,LOC107550099,LOC107552317,LOC107738316,LOC107698657
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047617.1
NCBI id CM018563.1
chromosome length 20335669
location 1804670 ~ 1842048 (+)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_034298573.1
agagagagagagagagagagagagagagagctggaagGTAGGCAGGTAGGCAGGGCAGGATTTACCTGTAGCCCAGGTTTGTGCTCTtgcctcgctctctctctgtctctgtgtgtgtgtgagtgtgtgtgtgtgagtgtgtgtgagtgtgtgaggctgCACCGACCTGAAAGTCCAGTTTCTCCAGGAATTATCGCCGAGGAGGccaaaaacatcatcatgtCACAGGACACAGACAAcagtaagaggctgctggtggtggtcCCTAACGATCCTCTTCATGGGCGTCGCTCGTACACCAGTGAGGATGAGGCGTGGAGGTCGTACCTGGAGAACCCGCTCACTGCCGCCACTAAAGCCATGATGAGCATCAACGGAGACGAGGACAGCGCCGCCGCTCTGGGACTGCTGTACGAGTACTACAAGGTTCCTAAAGATAAGAGGGTGCTGCCCATTAGCAAAGTGGTGGAAGTGGTGGAGGAACAGGAGAAAAGCAGTGTATCCGACCCTCCGTCAGTAGATAATCACGTTCAGGTGTTGAAGTCAGTTCCGGTGAATCTGTCTCTCAGCGCCGAGCCTCACGACTCCAAGCGGGACGGCTTCACCGAAAGCGGCCACGTTGCCACGGTGAAGGCCGAGGGGTACGCCCCCGTCTTCATGAACTCCGCCCTTCAGTACCGTAACGAGGGCGAGGAGCAGGCGAGGGTGGGGTATGAACAGAGCGCGCACTCGATGAGCGCCGATCACGCCGAGTACGGGAGAGACGCACAGCGCAGCAGCCCCGACAGCACGTACGACGACGAGGACGACGGCGCAGAGAAATATCGTCCCTCGTCTCTCGGAGCCAACGAGTTCATCTTCGAACAATCAAACATAGACACGTTCCAGTACACTTTAGACGCCACGAGGTCGCTGAGACAGAAACAGGGCGAGGGGCCGATGAGTTACCTGAATAAAGGACAGTTTTACGCCGTGACGCTGAACGAGACGAGCAGCAACAAACGCCTGAGACACCCCATCAGCAAAGTGCGGaGTGTCGTCATGGTGGTGTTCAGTGAAGATAAGAACCGAGATGAACAGCTGAAGTACTGGAGATATTGGCACTCTCGCCAACACACGGCTAAGCAGCGGGTCCTCGACATcgCGGACTACAAAGAGAGCTTCAACACGATCGGGAACATCGAGGAGATCGCCTACAACGCCGTGTCCTTTACGTGGGACGTCAACGAAGAGGCCAAGatcttCATCACTGTGAACTGCCTGAGCACAGACTTCTCCTCTCAGAAGGGAGTGAAGGGTCTGCCGCTGATGATCCAGATCGACACGTACAGCTACAACAACCGCAGCAACAAACCACTGCACAGAGCATACTGCCAGATCAAAGTGTTCTGTGAtaagggagcAGAGAGGAAGATCCGAGACGAGGAGAGGAAGCAGAACCGCAAGAAGTCAAAAGGGAAAGACGCGGGTGCCGGAGTGGTCAGTCTGCCCAAAAAGGGCGACACCACGCTGTTCAGGACGATGACGGATCTGGACGCTCAGCCCGTCCTCTTCATCCCCGACGTACACTTCGGAAACCTGCAGAGAGCGGCGCAGGTTTTTGCCTTCAACACTGACGAGATCGAGAGAGAAGGgagtGTATTAGTAAAGAGGATGTTCCGGTCAGCAGAGGATGATTGTTGTCCTTCGCCTCATAAACAGCTCAGAGAGGAACCACAGAAAAGAGtgctCCTGTACGTCAGAAAAGAGAGTGACGAGGTGTTCGATGCTCTCATGCTGCGTTCACCGACGCTCCGAGGCCTCATGGACGCAATCTCAGAGAAGTACAGCGTGCCTGTGGAGAGGATCGCTAAAATCTACAAAAAGAGCAAGAAAGGGATCCTGGTGAACATGGACGACAACATCATCGAGCATTACTCCAACGAGGACACGTTCATCCTGAGCATCGAGAGCTACGCCGACGCCTACAAAATCACTCTGACCGagatttagactttttttttttcggaaaTTGGGAACATGAAGAGCTGAAGAGTTCTTTCCAGCGTCATGGTGGAAGCAGTGCAGCGTTCAACGTCTGCGCCGTCAAAACGTCGACGTACGATTTCAAATCAGGTTCAAACGAAGCGGCTTCTTCTAGAGCCGTCCTTCTACACAAACATGAAGAGTCGACTCGTCAGTCACGTGATTCCCGACTTAACTCAAATCAGAGACCGAACAGGAAGTTCTcctgtgtgtaataatgtgataTTGCTTTATAGGTGTTTGTTACAAACATAAATTCAGGACGATACAGAGGCAGTAAAATCCGAGAGGTGAACATTTCTATTCCATAAACTGTAAGTACATTTTCTTATGGTGATGTAtcatttctatttcatttttattttattttttgtgaaaatttcACGGCTGAAAATTTTAGTCTTACACATTTCAGATGAACAGCCTCATCTTTAAGctgatacatatatatttttagttttctattagaaatataatttcccaaaatacacatatttctaatgtgaaaagaaaaaaacaagaacacatTGTGAACACCGTGCTGcaggatataaaaataaattaatatatctatctaaaatataatttataaattgaaTCCACCAGTTTGGATTCAAAGCAAGATTGGATTCAAAAAGTGGAttcaaaaaatttaaaaacaaattggattaaaaaattggatt
>XM_034298574.1
gagagagagagagagagagagagagagagagctggaagGTAGGCAGGTAGGCAGGGCAGGATTTACCTGTAGCCCAGGTTTGTGCTCTtgcctcgctctctctctgtctctgtgtgtgtgtgagtgtgtgtgtgtgagtgtgtgtgagtgtgtgaggctgCACCGACCTGAAAGTCCAGTTTCTCCAGGAATTATCGCCGAGGAGGccaaaaacatcatcatgtCACAGGACACAGACAAcagtaagaggctgctggtggtggtcCCTAACGATCCTCTTCATGGGCGTCGCTCGTACACCAGTGAGGATGAGGCGTGGAGGTCGTACCTGGAGAACCCGCTCACTGCCGCCACTAAAGCCATGATGAGCATCAACGGAGACGAGGACAGCGCCGCCGCTCTGGGACTGCTGTACGAGTACTACAAGGTTCCTAAAGATAAGAGGGTGCTGCCCATTAGCAAAGTGGTGGAAGTGGTGGAGGAACAGGAGAAAAGTGTATCCGACCCTCCGTCAGTAGATAATCACGTTCAGGTGTTGAAGTCAGTTCCGGTGAATCTGTCTCTCAGCGCCGAGCCTCACGACTCCAAGCGGGACGGCTTCACCGAAAGCGGCCACGTTGCCACGGTGAAGGCCGAGGGGTACGCCCCCGTCTTCATGAACTCCGCCCTTCAGTACCGTAACGAGGGCGAGGAGCAGGCGAGGGTGGGGTATGAACAGAGCGCGCACTCGATGAGCGCCGATCACGCCGAGTACGGGAGAGACGCACAGCGCAGCAGCCCCGACAGCACGTACGACGACGAGGACGACGGCGCAGAGAAATATCGTCCCTCGTCTCTCGGAGCCAACGAGTTCATCTTCGAACAATCAAACATAGACACGTTCCAGTACACTTTAGACGCCACGAGGTCGCTGAGACAGAAACAGGGCGAGGGGCCGATGAGTTACCTGAATAAAGGACAGTTTTACGCCGTGACGCTGAACGAGACGAGCAGCAACAAACGCCTGAGACACCCCATCAGCAAAGTGCGGaGTGTCGTCATGGTGGTGTTCAGTGAAGATAAGAACCGAGATGAACAGCTGAAGTACTGGAGATATTGGCACTCTCGCCAACACACGGCTAAGCAGCGGGTCCTCGACATcgCGGACTACAAAGAGAGCTTCAACACGATCGGGAACATCGAGGAGATCGCCTACAACGCCGTGTCCTTTACGTGGGACGTCAACGAAGAGGCCAAGatcttCATCACTGTGAACTGCCTGAGCACAGACTTCTCCTCTCAGAAGGGAGTGAAGGGTCTGCCGCTGATGATCCAGATCGACACGTACAGCTACAACAACCGCAGCAACAAACCACTGCACAGAGCATACTGCCAGATCAAAGTGTTCTGTGAtaagggagcAGAGAGGAAGATCCGAGACGAGGAGAGGAAGCAGAACCGCAAGAAGTCAAAAGGGAAAGACGCGGGTGCCGGAGTGGTCAGTCTGCCCAAAAAGGGCGACACCACGCTGTTCAGGACGATGACGGATCTGGACGCTCAGCCCGTCCTCTTCATCCCCGACGTACACTTCGGAAACCTGCAGAGAGCGGCGCAGGTTTTTGCCTTCAACACTGACGAGATCGAGAGAGAAGGgagtGTATTAGTAAAGAGGATGTTCCGGTCAGCAGAGGATGATTGTTGTCCTTCGCCTCATAAACAGCTCAGAGAGGAACCACAGAAAAGAGtgctCCTGTACGTCAGAAAAGAGAGTGACGAGGTGTTCGATGCTCTCATGCTGCGTTCACCGACGCTCCGAGGCCTCATGGACGCAATCTCAGAGAAGTACAGCGTGCCTGTGGAGAGGATCGCTAAAATCTACAAAAAGAGCAAGAAAGGGATCCTGGTGAACATGGACGACAACATCATCGAGCATTACTCCAACGAGGACACGTTCATCCTGAGCATCGAGAGCTACGCCGACGCCTACAAAATCACTCTGACCGagatttagactttttttttttcggaaaTTGGGAACATGAAGAGCTGAAGAGTTCTTTCCAGCGTCATGGTGGAAGCAGTGCAGCGTTCAACGTCTGCGCCGTCAAAACGTCGACGTACGATTTCAAATCAGGTTCAAACGAAGCGGCTTCTTCTAGAGCCGTCCTTCTACACAAACATGAAGAGTCGACTCGTCAGTCACGTGATTCCCGACTTAACTCAAATCAGAGACCGAACAGGAAGTTCTcctgtgtgtaataatgtgataTTGCTTTATAGGTGTTTGTTACAAACATAAATTCAGGACGATACAGAGGCAGTAAAATCCGAGAGGTGAACATTTCTATTCCATAAACTGTAAGTACATTTTCTTATGGTGATGTAtcatttctatttcatttttattttattttttgtgaaaatttcACGGCTGAAAATTTTAGTCTTACACATTTCAGATGAACAGCCTCATCTTTAAGctgatacatatatatttttagttttctattagaaatataatttcccaaaatacacatatttctaatgtgaaaagaaaaaaacaagaacacatTGTGAACACCGTGCTGcaggatataaaaataaattaatatatctatctaaaatataatttataaattgaaTCCACCAGTTTGGATTCAAAGCAAGATTGGATTCAAAAAGTGGAttcaaaaaatttaaaaacaaattggattaaaaaattggatt

Function

symbol description
grhl2b Enables transcription cis-regulatory region binding activity. Acts upstream of or within apoptotic process involved in morphogenesis; inner ear development; and midbrain-hindbrain boundary morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including anterior axial hypoblast; midbrain hindbrain boundary neural rod; neurogenic placode; optic vesicle; and posterior lateral line system. Used to study autosomal dominant nonsyndromic deafness. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Orthologous to human GRHL2 (grainyhead like transcription factor 2).
grhl2 Enables DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including bicellular tight junction assembly; negative regulation of keratinocyte differentiation; and regulation of nucleobase-containing compound metabolic process. Located in cell-cell junction and nucleoplasm. Implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4.

NR:

description
grainyhead-like protein 2 homolog

GO:

id name namespace
GO:0021555 midbrain-hindbrain boundary morphogenesis biological_process
GO:0048839 inner ear development biological_process
GO:0060561 apoptotic process involved in morphogenesis biological_process

KEGG:

id description
K09275 TFCP2; transcription factor CP2 and related proteins

RNA

RNA id representative length rna type GC content exon number start site end site
XM_034298573.1 True 2708 mRNA 0.49 16 1804671 1842048
XM_034298574.1 False 2706 mRNA 0.49 16 1804670 1842048

Neighbor

gene id symbol gene type direction distance location
spag1a spag1,spag1a,LOC108438857,LOC107748364 coding upstream 102939 1683334 ~ 1701731 (+)
adck5 adck5 coding upstream 174674 1610614 ~ 1629996 (+)
lix1l lix1l,LOC107693252 coding upstream 195816 1596847 ~ 1608854 (+)
prcc prcc coding upstream 218208 1578998 ~ 1586462 (+)
mrpl24 mrpl24,LOC107559719,LOC107693309,LOC107669969 coding upstream 226514 1574337 ~ 1578156 (+)
psmg2 psmg2 coding downstream 41397 1883445 ~ 1891699 (+)
seh1l seh1l,LOC107668717,LOC107746927 coding downstream 78887 1920935 ~ 1932700 (+)
rnmt rnmt,LOC107746930 coding downstream 149766 1991814 ~ 2003334 (+)
mc5ra mc5ra,LOC108257298,LOC108438868,LOC103022384,LOC107746932,LOC107552309 coding downstream 184359 2026407 ~ 2039047 (+)
cthrc1a cthrc1a,cthrc1,LOC108257304,LOC108438867,LOC107746934,LOC107675657,LOC107668704,LOC107754923 coding downstream 217284 2059332 ~ 2065910 (+)
G336261 NA non-coding upstream 47266 1756185 ~ 1757404 (+)
G336256 pabpc1,LOC107672855 non-coding upstream 63663 1738163 ~ 1741007 (+)
G336275 NA non-coding upstream 216376 1586247 ~ 1588294 (+)
G336406 NA non-coding upstream 224370 1579795 ~ 1580300 (+)
G336267 NA non-coding upstream 253470 1549855 ~ 1551200 (+)
G336482 NA non-coding downstream 541 1842589 ~ 1842970 (+)
G336849 fam210a,LOC107675659,LOC107754921,LOC107566562,LOC107668710 non-coding downstream 123928 1965976 ~ 1984496 (+)
LOC117595895 NA non-coding downstream 359732 2201780 ~ 2203741 (+)
LOC117595896 NA non-coding downstream 400137 2242185 ~ 2259536 (+)
G336991 NA non-coding downstream 401445 2243493 ~ 2244230 (+)
polr2k NA other upstream 124318 1675040 ~ 1680352 (+)
G336433 parp10 other upstream 145211 1657317 ~ 1659459 (+)
G336334 NA other upstream 469096 1269809 ~ 1335574 (+)
G336350 cdk12 other upstream 477163 1325816 ~ 1327507 (+)
mllt11 mllt11 other upstream 668546 1132955 ~ 1136124 (+)
G336822 ldlrad4 other downstream 34226 1876274 ~ 1945866 (+)
LOC117595892 LOC108257284,LOC108257282,LOC108257281,LOC108257289,LOC108257310,LOC108272567,LOC108261104,LOC108280065,LOC108272472,LOC108261175,LOC108279530,LOC100526730,LOC108257326,LOC108257286,LOC108261265 other downstream 343844 2185892 ~ 2351749 (+)
LOC113546301 LOC108257282,LOC108257281,LOC108257284,LOC108257326,LOC108257289,LOC108257286,LOC108257310 other downstream 460097 2302145 ~ 2340261 (+)
LOC113546300 LOC108280069,LOC108261210,LOC108257281,LOC108257282,LOC108257284,LOC108257326,LOC108257286,LOC108257289 other downstream 516068 2358116 ~ 2392537 (+)
rsad1 rsad1 other downstream 2465874 4307922 ~ 4325036 (+)

Expression


Co-expression Network