AMCG00016275 (dyrk1a,LOC108435291)


Basic Information

Item Value
gene id AMCG00016275
gene name dyrk1a,LOC108435291
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030122.1
NCBI id CM030122.1
chromosome length 54868152
location 14192347 ~ 14199159 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00016275
ATGGCTGCGCAGATGCCTCATTCGCACCAGCCGTACAGTGACCGTCACCAGCAGGGTACGGACTCATCTGCCACGGCGTTGCCGTACAGTGACCAGGTCCAGCAGTCTACTGCCAACCAGGTGATTGCTGATGTGGTCTTGTTACAGAGGCGGATGCCCCAGACCTTTCGTGAACCAGCCACTGCTCCATTGAGGAAGCTCTCTGTTGACCTgatcaaaacatacaaacacatcaaTGAGGTATACTATGCAAAAAAGAAGAGACGACACCAACAAGGCCAGGGCGACGACTCCAGTCACAAGAAAGAGCGGAAGGTGTACAACGATGGCTACGACGACGACAACTACGATTACATAGTGAAGAACGGGGAGAAATGGATGGACCGCTATGAAATCGATTCCTTAATAGGCAAAGGCTCGTTTGGACAGGTTGTAAAGGCGTATGACCGTGTTGAGCAGGAGTGGGTGGCAATTAAGATCATCAAGAACAAGAAGGCTTTCCTGAATCAAGCCCAGATTGAAGTGCGGCTCCTCGAGCTTATGAACAAACATGACACCGAGATGAAATACTACATAGTTCACCTGAAGCGTCACTTCATGTTCAGGAACCACCTCTGCCTGGTGTTCGAGATGCTGTCGTACAACCTCTATGACTTGCTGCGCAACACCAATTTCCGCGGCGTCTCTCTGAACCTGACCCGCAAGTTTGCCCAACAGATGTGCACGGCCCTGCTGTTCCTCGCCACACCTGAGCTCAGCATCATCCACTGTGACTTAAAACCCGAGAACATCCTTCTGTGTAATCCTAAGCGAAGCGCCATCAAAATAGTAGACTTTGGTAGCTCTTGCCAACTGGGACAAAGGATATACCAGTATATCCAGAGTCGATTCTACCGGTCCCCCGAAGTGCTGCTGGGCATGCCTTACGACCTCGCTATCGACATGTGGTCTCTCGGCTGTATTCTAGTAGAAATGCACACCGGAGAGCCTCTCTTCAGTGGAGCCAATGAAGTGGATCAAATGAACAAAATAGTAGAAGTTCTTGGTGTCCCTCCCAATCACATATTGGACCAGGCACCCAAAGCCAGGAAGTTCTTTGAGAAGTTGTCAGATAGCACATGGGGTGTAAAGAAGACCAAAGATGGAAAACGGGAGTATAAACCCCCAGGTTCCCGTAAACTCCACAACATCCTCGGGGTGGAGGCGGGGGGTCCAGGAGGGCGACGTGCCGGGGAATCGGGCCACGCTGTAGCCGACTACTTGAAGTTCAAGGACCTCATCTTAAGAATGCTGGACTACGACCCTAAGACTCGCATTCAGCCCTACTATGCCCTGCAGCACAGCTTCTTCAAGAAGACGGCGGATGAAGGCACGAATACGAGCAACAGCGTGTCCACGAGTCCGGCACTGGAGCAGTCGCAGTCTTCAGGAACCACATCTAGCACCTCGTCGAGTTCAGGAGGCTCCTCTGGAACCAGTAACAGTGGACGAGCACGGTCCGACCCAACTCACCAGCACCGGCACAGTGGAGGACACTTCAGCGCCGCAGTGCAGGTGATGGACTGTGAGACCCACTGCCCACAGGTGAGACAGCCGTATCCACCTCCCGTGGGATGGACGGGTGGTGACGGTCCCCAGCAGGTCACCGTGGAGACTCATCCAGTCCAGGAGACCACTTTCCACGTGCCTCCCCCGCAGCCCAGCGCATTACACCACCACCCGAGCAGCAACAGCgcgcaccaccaccaccaccaccaccaccaccaccaccacggACAGGGCCTGGCCACGCGCAACCGCCCGCGGCTCTACAACTCCCCCACCAACAGCGCCTCCACGCAGGAATCCATGGAGGTGGTGCACAGCCACCTGTCCATGACCTCCCTGtcttcctctgcctcctcttcctccacatCTTCCTCCTCGACTGGGAACCAAGGCAACCAGACCTATCAGAACCGCCCGGTCGCTGCCAACGCCTTGGACTTTGGCCAAAACGGCAGCGCGGACATGGGATTGGGAGTGTTCTCGAATCCCCGTCAAGAGACTGGCATCACGGGACATCCGACCTACCAGATTGCGACGAACACGGGGGCGGCTCACTACATGACTGAGGGCCATCTGGGCATGAGACAAGGCATTGACAGGGAGGAGTCCCCCATGGCGGGGGTCTGTGTCCAGCAGAGCTCTGTGGCCAGTTCGTGA

Function

symbol description
dyrk1a Enables cytoskeletal protein binding activity; identical protein binding activity; and protein kinase activity. Involved in amyloid-beta formation; positive regulation of RNA splicing; and protein phosphorylation. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in cytoplasm and nucleus. Colocalizes with actin filament; microtubule; and neurofilament. Implicated in autism spectrum disorder; autosomal dominant non-syndromic intellectual disability 7; and intellectual disability. Biomarker of Down syndrome.

NR:

description
PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

GO:

id name namespace
GO:0046777 protein autophosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004712 protein serine/threonine/tyrosine kinase activity molecular_function

KEGG:

id description
K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00016275 True 2205 mRNA 0.55 10 14192347 14199159

Neighbor

gene id symbol gene type direction distance location
AMCG00016268 NA coding downstream 59693 14086954 ~ 14132654 (-)
AMCG00016266 NA coding downstream 170399 14012696 ~ 14021948 (-)
AMCG00016267 NA coding downstream 221495 13956767 ~ 13970852 (-)
AMCG00016263 NA coding downstream 255497 13936623 ~ 13936850 (-)
AMCG00016262 NA coding downstream 270391 13912922 ~ 13921956 (-)
AMCG00016274 NA coding upstream 34539 14233698 ~ 14258146 (-)
AMCG00016276 NA coding upstream 68477 14267636 ~ 14267815 (-)
AMCG00016277 NA coding upstream 69007 14268166 ~ 14269315 (-)
AMCG00016280 sim2,LOC108234774 coding upstream 107140 14306299 ~ 14324175 (-)
AMCG00016284 NA coding upstream 184741 14383900 ~ 14389479 (-)
G12373 NA non-coding downstream 532688 13657443 ~ 13659659 (-)
G12358 NA non-coding downstream 552757 13638303 ~ 13639590 (-)
G12359 NA non-coding downstream 553197 13627255 ~ 13639150 (-)
G12235 NA non-coding downstream 1092123 13097991 ~ 13100224 (-)
G12096 NA non-coding downstream 1553649 12638493 ~ 12638698 (-)
G12585 NA non-coding upstream 228466 14427625 ~ 14428817 (-)
G12594 NA non-coding upstream 232453 14431612 ~ 14436531 (-)
G12595 NA non-coding upstream 264458 14463617 ~ 14463823 (-)
G12702 NA non-coding upstream 994043 15193202 ~ 15193641 (-)
G12707 cntn5 non-coding upstream 1217864 15417023 ~ 15417518 (-)
AMCG00016246 prdm15,LOC108413920,LOC102786849 other downstream 633163 13543348 ~ 13559184 (-)
AMCG00016226 NA other downstream 1321787 12849878 ~ 12870560 (-)
AMCG00016211 NA other downstream 1863314 12323161 ~ 12329033 (-)
AMCG00016203 zdhhc20,LOC108438268,LOC106578454,LOC108256609 other downstream 2245025 11832428 ~ 11947322 (-)
AMCG00016194 NA other downstream 2410800 11766152 ~ 11781547 (-)
AMCG00016281 NA other upstream 221197 14420356 ~ 14427290 (-)
AMCG00016293 NA other upstream 586039 14785198 ~ 14791969 (-)
AMCG00016327 NA other upstream 2271452 16470611 ~ 16475170 (-)
G12945 ucp2,ucp2b,LOC106567822 other upstream 2659382 16858541 ~ 16861179 (-)
AMCG00016345 NA other upstream 2667159 16866318 ~ 16870002 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000203_00086596_00095920 DYRK1A, DYRK1AA coding CI01000203 null 84952 ~ 96172 (-)