AMCG00016420 (mre11a)


Basic Information

Item Value
gene id AMCG00016420
gene name mre11a
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030122.1
NCBI id CM030122.1
chromosome length 54868152
location 19281702 ~ 19316677 (-)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00016420
GTAGGAAAGACGGAGGGAGATTTCACGTGGCGTGAAACTGACATCACACAGTTTTGGAAACaatcctgaaaataaaaatcccaaaTGAGAAAGGTCTCCCTTTGATTAAATCAAACTGTGTATGTTCTGCTGTGTGTCCTGCTGACATTTTAACTTCAAGATGACCTCTGAAAATACCCgagatgATGAGGACACATTCAATATTCTGCTAGCCACCGACATTCACCTGGGGTACATGGAGAAAGATGCCATTCGGGGCAATGATACCTTTGTGACGTTTgatgagattttaaaatgtgcaaaagagAATGAGGTTGACTTTATATTGCTTGGTGGCGATCTGTTTCATGACAACAAACCCTCTCGGCGGACCCTGCACAGCTGTATGGAGCTAATGAGGAAGTATTGCATGGGAGAGCGGCCTATAGTCTTTGAAATCCTCAGCGATCAAGCAGTAAATTTTAGCAATAGCAAgtttCCATGGGTGAACTATCAAGATGAAAATCTGAACATCTCCATTCCGGTCTTTAGTGTGCATGGTAACCACGACGATCCCACGGGGGCAGATGGTCTGTGTGCGCTGGATATCTTGAGTTGTGCTGGACTGGTTAATCACTTTGGCCGCAGCAGGTCTGTGGAGAAGATTGAAATCAGTCCCATTCTTCTGCAGAAAGGAAACACAAAGATATCGTTGTATGGCATTGGGTCCATCCCAGATGAGAGGCTTTACAGGATGTTTACCAATAAACAGGTGGTCATGCTCAGGCCCAAGGAGGATGAAAATAGCTGGTTCAATCTGTTTGTTATCCATCAGAACAGGAGTAAACACGGGGCCACTAATTACATCCCTGAGCAGTTTCTGGACGACTTCCTGGACTTGGTGGTGTGGGGTCACGAGCACGAGTGCAAGATCGCCCCGGTCCGCAACGAGCAGCAGCTCTTCTACGTCACGCAGCCGGGGAGCTCTGTCGTCACGTCGCTTTCTCCGGGGGAGGCGGTCAAGAAACACGTGGGCCTGCTGAGAATCAAGGGGAAGAAGATGAACCTGCAGAAGATCCCTCTGCACACAGTGCGTCAGTTCTTCATCAACGATGTGGTATTGGCGGACCACGCCAGCCTCTTCAACCCAGACAACCCCAAGGTCATGCAGAAAATAGAGGCCTTCTGCAACGAAAAGGTGGAGGAGATGCTGGAGCAGGCAGAACGAGAGCGGATGGGGAATTCCTTGACTCCAGAGAAGCCGCTCATTCGCCTGAGGGTTGACTACAGTGGGGGATATGAACCATTCAACATGATGCGATTCGTCCAGAGGTTTGTGGACCGAGTGGCGAACCCAAAGGACGTTGTGCACTTCTTCAGACACAGAGACCAGAAGGATAAAAAAGatgatgAAAACATTAACTTTGATCAGCTGGTGAACAGGACCTCATCTGAAGTCATGCAGTTAAGAGTGGAGGACTTGGTGAAACAGTACTTTGAAACAGCAGAGAAAAGCGTGCATCTGTCCCTGCTGACGGAGCAAGGCATGGGGAAGGCAGTACAGGAGTTTGTGGACAAGGAGGAGAAGGACGCCATTGAGGACCTGGTTAACTTCCAGCTGGAGAAAACACAACGCTTCCTGAAGGAACGCCACATAGAAGCCGCTGAGGACAAGATCGATGAGGAGATTCGCCGTTTACGAGAATCAAAAAAGACAACcgcagaggaagaggaggaagtcCAGCAGGCTATCAGCAAAGCTAAAGCCATGCGTGGACAGCCCTCCTCGTTTGTGGACGATGTGATGGACGTGTCTGAAGACTTTGGGATGGACTCCGATGACAGTGGCCCTCCACCCTCAGTGTCGACACGTGGCAGGGGCAGGGGACGTGCGCGAGCAGCCAAGAGAGCCGCCTCCCAGATGGAGCCAAAGCCTACTGGCCGAGGACGCTCCTACAAAAAGCCACTGATCAGCCCCTCCAAAAACATGTCCATCTTAGATGcCTTCAATTCCAGTTCTCAAAGGCCTTCTCGAAGTTCAGCCCCTCCAAAATCAGAAGAGATTATAATTGATGATGACTCGGATGACGACGCAAGTTTTTCCCAGCCTTCCAAACCTAATCAGAGGGCTTCCAGGGTGTCAAGTAAGACAAGCTCCCAGAGTCAGTCGCTGAAGGGGCTGTGTTTTGAAGATGATGAAGATGAGGATGAATACAATCCCTTTAAGAGCTCCGGCAGCTCGAACAGAAGAAGCCGCAGATAGCTGATAGAAAAGACGTCTACCCCGCCACATGCCTCCGATTGTTCTATCATGGGCTTCTTTATTGTGATTGCTTTCTACCCTTTTCCATCGCTGAGATTCGAGTGTTTCGCATGGTTTAGGTTATCAGCTGCACCCACACGCAGTGACTTACTGAACACCAGGATGAGTCAGACTGCACTTCAGGTGGAAAAAGGGTTCTCTCTAGGTATTTCAAGCCAGATCCCCCTTTGTTCGTctgtgttttttgctttgttgtggCACTGCCATTGCCATTGCCATTGATGAAACTCAGAGTGGTTGTAACTTAATTCAGCTTTAAGTGGGACCTTTGAATGGCTTTAGAGAAGCAGCCTTGAATTGTACACAGAAGCAtttaattccatttatttttcatttttctttggttatttttctttattactgGAATTGCATCCATAAGAAcccaaaactttgacctacccttgaattgcaaattatacatttataccctattttgttttgttttagaagaGAAAGTGTCTTCTGACAATACACTAAACTGCGATGGGGTATGTTTGTATGCAAAGCTCAAATAAGAAGGAAATACCGATAGTAAATGCTAGTAATCGCCAGTGTAGGTAAGAGACTTAACTCTGCAGTCCTCTTTGTTCCTTTTTGTCCTTCACAGCTTTActcttaaatgtaattgtaatatagtAATTCAAGGGTATAATTACTCAGGAAAGCAAGGAGATTTTCTGTCATaaagaatacacattttctgcCAATTATACGCCCCCATCTCTCGCCTTGCCTTGCAACAGAATAACCGCACTGAGCAGTTATGTGGGAATTGCAAATAATGGTATGACTACCCCCTATACATACACTGacaaaaactaagaaacaatgAATACTATACAATAAAAGGAacgttttgtttcctttcttgaGTAGCTACTCAACACTGCACCTTCAATTctagttgtttatttttctgagaTTTCCAGTATGTGCACTGTTGCCTTGCACCTATAATTTTCAAATTCAGTGAATTAACATCCCCTCTTACAcatttcttcattgtttttactATATCATCCTTGCACACCTGTTATATTGGAGCTTTTATCCTCTTCAAGTGATTTGGTATGGGATTAGCTAAATGAATCTGTCCATCATCTTTACTCCAAGTGAACtcacttatttttcttcagctgTAGTCTGTTGGATTATAGTTTAAGCTGCCATCTCTACAAACTATTAAGTAATGATTGCTGTTTATTAAagaaattatcattatttctttTGATTAATCACCATTGTGTTTCGGGACGAACTGATTATATGCAATGTgaacatttgtacatttattattaaagagACATTTTGTACCCAA

Function

symbol description
mre11a Predicted to enable single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in mitotic DNA damage checkpoint signaling and nucleic acid metabolic process. Predicted to act upstream of or within double-strand break repair and meiotic cell cycle. Predicted to be located in nucleus. Predicted to be part of Mre11 complex. Predicted to be active in site of double-strand break. Is expressed in alar plate midbrain region; digestive system; eye; immature eye; and midbrain. Human ortholog(s) of this gene implicated in breast carcinoma; endometrial cancer; stomach carcinoma; and urinary bladder cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease).

NR:

description
PREDICTED: double-strand break repair protein MRE11A

GO:

id name namespace
GO:0006302 double-strand break repair biological_process
GO:0090305 nucleic acid phosphodiester bond hydrolysis biological_process
GO:0005634 nucleus cellular_component
GO:0030145 manganese ion binding molecular_function
GO:0004519 endonuclease activity molecular_function
GO:0004527 exonuclease activity molecular_function

KEGG:

id description
K10865 MRE11; double-strand break repair protein MRE11

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00016420 True 3620 mRNA 0.45 20 19281702 19316677

Neighbor

gene id symbol gene type direction distance location
AMCG00016419 NA coding downstream 2034 19277298 ~ 19279668 (-)
AMCG00016414 NA coding downstream 76108 19184938 ~ 19205594 (-)
AMCG00016410 NA coding downstream 119974 19155334 ~ 19161728 (-)
AMCG00016409 NA coding downstream 138184 19109142 ~ 19143518 (-)
AMCG00016404 NA coding downstream 242198 19025838 ~ 19039504 (-)
AMCG00016418 cwc15,LOC100196400 coding upstream 49407 19366084 ~ 19375596 (-)
AMCG00016424 sesn3 coding upstream 61323 19378000 ~ 19406939 (-)
AMCG00016423 fa76b,fam76b,LOC106603374 coding upstream 110778 19427455 ~ 19437740 (-)
AMCG00016425 mtmr2 coding upstream 129877 19446554 ~ 19455857 (-)
AMCG00016426 pde2a coding upstream 143616 19460293 ~ 19498100 (-)
G13414 NA non-coding downstream 23145 19258323 ~ 19258557 (-)
G13413 NA non-coding downstream 24783 19256638 ~ 19256919 (-)
G13392 NA non-coding downstream 28288 19165586 ~ 19253414 (-)
G13366 NA non-coding downstream 193070 19088224 ~ 19088632 (-)
G13341 NA non-coding downstream 203879 19077368 ~ 19077823 (-)
G13615 NA non-coding upstream 686472 20003149 ~ 20004940 (-)
G13680 NA non-coding upstream 999065 20315742 ~ 20316579 (-)
G13762 NA non-coding upstream 1151569 20468246 ~ 20513404 (-)
G13766 NA non-coding upstream 1170204 20486881 ~ 20492021 (-)
G13789 NA non-coding upstream 1278652 20595329 ~ 20598765 (-)
G13367 NA other downstream 176321 19091239 ~ 19105381 (-)
AMCG00016376 NA other downstream 1740360 17538034 ~ 17541342 (-)
AMCG00016360 aamdc,LOC107658908,LOC107660681,LOC107600345,LOC107600309 other downstream 2014955 17263601 ~ 17266747 (-)
AMCG00016345 NA other downstream 2411700 16866318 ~ 16870002 (-)
G12945 ucp2,ucp2b,LOC106567822 other downstream 2420523 16858541 ~ 16861179 (-)
AMCG00016453 NA other upstream 812231 20128908 ~ 20135547 (-)
AMCG00016479 NA other upstream 1299832 20616509 ~ 20636960 (-)
AMCG00016480 NA other upstream 1349465 20666142 ~ 20683024 (-)
G13962 NA other upstream 4138415 23455092 ~ 23455811 (-)
G13969 NA other upstream 4382472 23699149 ~ 23700255 (-)

Expression


Co-expression Network