AMCG00018526 (fscn1a,fscn1,LOC107742378,LOC107581720,LOC107674660)


Basic Information

Item Value
gene id AMCG00018526
gene name fscn1a,fscn1,LOC107742378,LOC107581720,LOC107674660
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030135.1
NCBI id CM030135.1
chromosome length 28454832
location 13639723 ~ 13649092 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00018526
ATGACGGCAAACGGAATCAGCGATATGGTCCAAATCCAGTTTGGGCTCATCAACTGTGGGAACAAATACCTCACGGCTGAAGCGTTTGGTTTTAAGATCAACGCCTCTGCCATCAGCATGAAGAAGAAGCAGATCTGGACCCTGGAGCAGGATGGTGATGACTCCAACGTGGTCTTCCTCAAAAGCCACCTGGGCAGGTACCTGGCAGCTGACAAGGACGGCAACATCACCGGGGATAGCGAGACCACCGTCGTGGACTGCAGATTCATCATCATTGCCCACGACGACGGGCGCTGGTCTCTGCAGTCGGAGCCTCACAAGCGCTACCTGGGCGGCACCGAGGACCGGATCACCTGCTTTGCCCAGACCATCTCGGTGGCGGAGAAATGGAGCGTCCACATCGCCATGCACCCtcaagtcaacatcttcagcctcACCAGGAAGAGATACGCTCACCTGAGCTCCAAGCAAGACGAGATTGCCATCGATAGAGATGTCCCTTGGGGAGTCGACTCCTTGATCACGTTGGTCTTTCAGGACCAGAGGTACAGTCTCCAGACATCCGACAACCGCTTCCTGAAGAATGACGGCTCGCTGGCCGAGAAATCCGACAAAACCACCGGGTACACCTTGGAGTTCCGCTCGGGAAAGGTAGCCTTCAGGGACTGCGAGGGGAAATACTTGGCTCCCTCGGGGCCCAGTGGGACCATGAAGTCTGGGAAGAGCTCCAAGGTGGGAAAAGACGAGCTGTTTGTACTGGAGCAGAACCATCCACAAGATGAGGAAGGAGACCAAGAGACCTTTCAAATGGAGATCAGCAAAGACACCAAGAAGTGTGCTTTCAGAACCTGTGCTGGGAAGTACTGGACCCTTACCCCCAATGGAGGAGTACAGTGCACTGCCTCCACCAAgACTCCTAACTGTTACTTTGACATTGAGTGGCGTGAGAAGAAAATCACTTTGAAGGCCTCCAATGGGAAATATGTGGCCGCCAAAAAGAATGGCCAACTTGCAGCCACCACTGACTCTGCAGGTGACACTGAAGAGTTTCTGATGAAGCTCATTAACAGGCCCATCATCGTCCTGCGAGGAGAGCATGGGTTCATTGGCTGCAGGAAGGTGACCGGTACCCTGGACTCCAACCGCTCCTCATACGACGTCTTTCAGCTGGAATTCAACAATGGAGCGTATAATCTCAAAGATTGCACTGGTAAGTACTGGATGGTTGGCAACGAATCTTCTGTGGTGAGCAGCAGTGACACCCCGGTGGACTTCTTCCTGGAGTTCTGTGACTACAACAAGGTGGCAATCAAGTCCTCGGGTGGCAAGTACCTGAAGGGGGACCATGCTGGCGTGCTCAAAGCCAATGCTGACAGCATTGAGAGCTCCACA

Function

symbol description
fscn1a Enables actin filament binding activity; protein-macromolecule adaptor activity; and signaling receptor binding activity. Acts upstream of or within several processes, including animal organ development; epiboly; and pharyngeal system development. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including lamellipodium; microvillus; and ruffle. Is expressed in several structures, including head; mesoderm; nervous system; neural crest; and neural plate. Orthologous to human FSCN1 (fascin actin-bundling protein 1).
fscn1 Enables actin filament binding activity and drug binding activity. Involved in several processes, including microspike assembly; positive regulation of cellular component organization; and regulation of plasma membrane bounded cell projection assembly. Located in several cellular components, including actin cytoskeleton; microspike; and ruffle. Biomarker of cholangiocarcinoma; common bile duct neoplasm; pancreatic cancer; and pancreatic ductal carcinoma.

NR:

description
fascin

GO:

id name namespace
GO:0005856 cytoskeleton cellular_component
GO:0005737 cytoplasm cellular_component
GO:0030674 protein-macromolecule adaptor activity molecular_function
GO:0051015 actin filament binding molecular_function

KEGG:

id description
K23551 FSCN1; fascin 1

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00018526 True 1392 mRNA 0.54 5 13639723 13649092

Neighbor

gene id symbol gene type direction distance location
AMCG00018523 tnrc18,LOC107742388 coding upstream 104896 13468893 ~ 13534827 (+)
AMCG00018515 cpsf4,LOC107578701,LOC107720053 coding upstream 387478 13246534 ~ 13252245 (+)
AMCG00018516 bud31,LOC106595689 coding upstream 402037 13235201 ~ 13237686 (+)
AMCG00018514 NA coding upstream 443526 13187923 ~ 13196197 (+)
AMCG00018509 NA coding upstream 473578 13162657 ~ 13166145 (+)
AMCG00018527 NA coding downstream 133622 13782714 ~ 13785549 (+)
AMCG00018530 LOC108430595 coding downstream 210803 13859895 ~ 13878065 (+)
AMCG00018534 arpc1a,LOC107720063,LOC107674705,LOC107591778 coding downstream 236688 13885780 ~ 13902661 (+)
AMCG00018533 mmd2,LOC107725363,LOC103909971 coding downstream 292536 13941628 ~ 13960988 (+)
AMCG00018536 NA coding downstream 323458 13972550 ~ 13985601 (+)
G116882 NA non-coding upstream 272695 13366640 ~ 13367028 (+)
G116790 NA non-coding upstream 424371 13129738 ~ 13215352 (+)
G116775 NA non-coding upstream 591629 13047117 ~ 13048094 (+)
G116765 NA non-coding upstream 681171 12905100 ~ 12958552 (+)
G116941 NA non-coding downstream 16931 13666023 ~ 13691367 (+)
G116975 NA non-coding downstream 190624 13839716 ~ 13839971 (+)
G116976 NA non-coding downstream 197798 13846890 ~ 13847092 (+)
G117130 NA non-coding downstream 593772 14242864 ~ 14244203 (+)
G117131 NA non-coding downstream 595616 14244708 ~ 14245318 (+)
AMCG00018520 slc29a4,LOC107703421,LOC107737679,LOC107581724 other upstream 292846 13307898 ~ 13346877 (+)
G116832 NA other upstream 383929 13253343 ~ 13255794 (+)
AMCG00018498 NA other upstream 1027844 12543545 ~ 12611879 (+)
AMCG00018491 slc5a10 other upstream 1119392 12503023 ~ 12520331 (+)
AMCG00018493 prpsap2,LOC107737786,LOC107581734,LOC107720040,LOC107654541 other upstream 1139669 12489467 ~ 12500054 (+)
AMCG00018537 radil,LOC107725399,LOC107722964,LOC107590699,LOC107564693 other downstream 348817 13997909 ~ 14022806 (+)
G117033 NA other downstream 397167 14046259 ~ 14049153 (+)
AMCG00018538 LOC103397138,LOC107554284,LOC100698873 other downstream 492285 14141377 ~ 14145995 (+)
AMCG00018553 cryba4,LOC106568369,LOC106563090 other downstream 539911 14189003 ~ 14191077 (+)
AMCG00018551 NA other downstream 590150 14239242 ~ 14242717 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_025621 fscn1a coding NC_007114.7 CM002887.2 40576447 ~ 40589489 (+)
grasscarp (Ctenopharyngodon idella) CI01000046_03761959_03768003 FSCN1, FSCN1A coding CI01000046 null 3760451 ~ 3768116 (-)