AMCG00018679 (nf2,nf2a,LOC108431713,LOC107726729,LOC107599150)


Basic Information

Item Value
gene id AMCG00018679
gene name nf2,nf2a,LOC108431713,LOC107726729,LOC107599150
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030135.1
NCBI id CM030135.1
chromosome length 28454832
location 17840752 ~ 17866985 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00018679
GGGGTCGGGGCCTCCTCCACCGCGGGCTCGGAGTGATGTGTTGCTCCTGATGTTGCAGCTTTGTGTGGCGATCAGTGTTTGGAAAGTTACTTTTCACGGGCGCAAAGTGAAAGGGGGATGGTGATGCCGTGGAGTTTCTGGCCAGGGATCCCCTGTTTTACCAGCCACAAAATGCAGGGAGTGTTGGGAAGTAGTTGGAAAGTTGCGTTTTCCACAGAAAAAGCGAACAGCAACTGGGACTAAATGTAGTTTcaatgcagctttttttttttagtattagCGGTCAAGAAACCGTGGTATTTTAACACGCACTGAACTGAAAATACAAGAAGAGGACTAGCAGTGGAGACAATGATCAAGAAAGCACAATAAAAAAGGCGAAAAAGTGTGCATAGTGTGCTTTAACTTGACGTCACCACACCGTATCCACGTGGAATGATGTGAATcttaaatctgtgtttttttatggatGTGAAAAGGGATTTTGCATGAAAGGATCACTTTTACAGCATGACATCCTGCTTTTTGAAATGTCCCGTTTAACCCCACGTCATCAGTTCTCTCATTGGGAATGACAGCAACatgtttctaaaatgaaaaccataacaCCCGAGTGACTGGGATTGTGTATCCATGTGGAAGAAAACTGGATCAGTAAATAACTGAATCTTCAATCCGCTTCAAGAAGTGCATTTCAGTAATGAAATAAAGGGACGCTGCTCTTATTGAATGACATGGTTGTTTAATACAGTTCTTTCTATAAGAGATGCTCCTCTGAGGAACTTTGATTGAGATCAGAAAACGCTGGGGTCACACATTATCACACATCTGCTCACTGGATATCGCCCTCTGTGCTCTGCTGATGTGATGGACTGTGACATGGCTTCACACTAGAAGAATGATCCCAAAGCAGATGTGTACATTGGATTGATCTTTACACCAGTGCATATATTTTCAAGGGCTTTCCAGCTTCTAGTGATCATGGCCAGCGCCATAGCCTCAAAGATGGGTCTGAGCTCCTGGAGGAGAAAACACAGCAAGGCTTTCAACGTGCGGATCGTCACCATGGATGCTGAGATGGAGTTCAGCTGTGAGGTCAAGTGGAAAGGGAAGGACCTTTTCGATTTGGTTTGCAGGACTGTGGGCCTGAGGGAGACCTGGTTTTTCGGACTTCAGTACAATGTGAAGGACACGGTGGCCTGGCTTAAAATGGACAAAAAGGTCTTGGACCACGACGTTCCAAAAGAAGAGCCGATCACCTTCAATTTCCTGGCCAAATTCTATCCAGAAAATGCAGAAGAGGAGCTTGTACAAGACATAACACAGCACCTTTTCTTCCTGCAGGTGAAGAAACAGATACTGGATGAAGAGATCTATTGTCCACCAGAGGCTTCAGTCCTGCTGGCTTCATACGCCGTCCAGGCCAAGtatGGAGACTATGATCCCGGTGTGCACAATCCAGGGTTTTTGGCTCAAGAAGAGCTGTTGCCAAAGAGGGTGATAAACCTGTATCAGATGACGCCCGAGATGTGGGAAGAAAGAATAACTGCCTGCTATGCCGAACACAGGGGAAGAACAAGGGACGAAGCAGAGATGGAGTATTTAAAGATAGCTCAGGACCTGGAGATGTATGGTGTGAACTACTTTTTCATTAGGaATAAAAAGGGAACAGACTTGCTGCTAGGGGTGGACGCTTTAGGTCTCCATATATACGATCCCGAGAACAGACTCACTCCCAAAATCTCCTTTCCCTGGAATGAAATCCGTAACATCTCCTACAGCGATAAAGAGTTTGCGATAAAGCCCTTGGACAAGAAGACGGATGTGTTTAAGTTTAACTCCTCTAAACTACGAGTCAATAAATTGATTCTCCAGCTGTGCATCGGGAATCACGATCTCTTCATGCGCAGGAGGCGGGTGGATTCTCTGGAGGTGCAGCAGATGAAGTCTCAGGCCAGGGAGGAAAAAGCGAGGAAGCAGATGGAGCGTCAGCGGCTGGCTCGGGAGAAGCATCtaagggaggaggcagagcgATCGAGAGACGAACTTGAGAGGAGGCTACTTCAGCTGCAGGACGAGGCGCAGATGGCCAACGAGGCCCTGATAAGATCAGAGGAGACTGCAGACCTGCTGGCGGAGAAAGCCCAGATAGCTGAGGAAGAGGCCAAGCTACTGGCCCAGAAGGCGGCCGAGGCCGAGCAGGAGATGCAGAGGATCAAAGTGACGGCCATCCGCGGCGAGGAGGAGAAGAGGCTGATGGAGCAGAAGATGTTGGAGGCCGAGATGCTGGCGCTCAAAATGGCAGAGGAGTCGGAGAGAAGGGCCAAAGAGGCGGAGCTGCTGAAGCAGGACTTGCAGGAGGCCCGGGAGTCGGAGCGCAGGGCGAAACACAAACTGTTGGAAATCACCAGCAAGTCTGCGTACACGCCCACCAGTTCGTCCGCGAACGCCATGCCCCCCGACATCCCCAGCTTCAACTTCAGCACCGAGAACCTCACCTTCGATTTCAAAGACACCGACATGAAGCGACTCTCCATGGAGATCGAGAAGGAAAAAGTGGAGTACATGGAGAAGAGTAAACACTTGCAAGAGCAGCTGAACGAACTGAAAACGGAGATTGAATCTCTGAAGCTGAAGGAGAGGGAGACCCCTTTGGACATCTTGCACAATGAGAATACCGAGAAGGGAACCAGCAAACAGAGCAACTTTAAGAAgCTTACTTTACAGAGCACAAAATCCAGAGTTGCCTTCTTCGAAGAACTCTAGGCTCCTAAAGGGACTCCCCAACCCCCAACTGAAGTCCCGGAATCGCAAGCTCTGAAGGCAGAAATGACACCGGACTTGTATGTAGTCCAACGCAAAGACACTGACCAAGTCCAGAGCATTTGGAGGGAAGCGTTTTACATTCACAACCACAGTGAAAATCTCAAGACGCACCAAGAGTGTTAAGTTTCTCTAAATGAGTTTTGCATTTGAAGTGGCAAGACTGTGTGAAGCTTCTGAACATAACTGACATTAAGGAAGAACGTCGgttatatcacttttttttttacgtgcgagtgaaaacaaatagaaaggcCGTCGTAAAGGTTATCGTGTGAATTTCATATTATTGGATGTGACAGTAAACTGACaatgtgttattgtgtttaTGAGCAGGGACGCTATGAACTGTTTGCAATGTAAAGTGCATTGACCGTTTGATGAACAACGTTGACGccttcattaaatataaatatacgaTGGTCTGTGtactgttcttatttatttaacgtGAACGAATGCTCAGTTTAATCCTAA

Function

symbol description
nf2a Predicted to enable actin binding activity. Predicted to be located in cytoplasm; cytoskeleton; and plasma membrane. Human ortholog(s) of this gene implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Orthologous to human NF2 (neurofibromin 2).
nf2 Predicted to enable actin binding activity. Involved in several processes, including Schwann cell proliferation; positive regulation of stress fiber assembly; and regulation of signal transduction. Located in several cellular components, including early endosome; nucleolus; and perinuclear region of cytoplasm. Implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Biomarker of acoustic neuroma.

NR:

description
PREDICTED: merlin

GO:

id name namespace
GO:0008285 negative regulation of cell population proliferation biological_process
GO:0005856 cytoskeleton cellular_component
GO:0019898 extrinsic component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003779 actin binding molecular_function

KEGG:

id description
K16684 NF2; merlin

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00018679 True 3300 mRNA 0.47 16 17840752 17866985

Neighbor

gene id symbol gene type direction distance location
AMCG00018668 NA coding upstream 17152 17807007 ~ 17823600 (+)
AMCG00018673 NA coding upstream 36804 17797953 ~ 17803948 (+)
AMCG00018666 NA coding upstream 51312 17786712 ~ 17789440 (+)
AMCG00018665 NA coding upstream 58052 17779697 ~ 17782700 (+)
AMCG00018667 gatsl3,LOC100696475 coding upstream 70216 17752323 ~ 17770536 (+)
AMCG00018678 LOC104923679,LOC100329495,LOC107386260,LOC102231850,LOC107599169 coding downstream 66760 17933745 ~ 17959525 (+)
AMCG00018685 prodha,LOC100695866,LOC108439536,LOC107373658,LOC106514456 coding downstream 156042 18023027 ~ 18035628 (+)
AMCG00018686 NA coding downstream 271060 18138045 ~ 18139541 (+)
AMCG00018698 NA coding downstream 478972 18345957 ~ 18437784 (+)
AMCG00018697 NA coding downstream 660758 18527743 ~ 18528121 (+)
G117887 NA non-coding upstream 255640 17584751 ~ 17585112 (+)
G117813 NA non-coding upstream 587729 17250869 ~ 17253023 (+)
G117808 znrf3,LOC106584905 non-coding upstream 616143 17224012 ~ 17224609 (+)
G117805 NA non-coding upstream 679029 17161514 ~ 17161723 (+)
G117804 NA non-coding upstream 679712 17160762 ~ 17161040 (+)
G117959 NA non-coding downstream 112026 17979011 ~ 17980939 (+)
G118005 LOC101154678 non-coding downstream 350818 18217803 ~ 18218099 (+)
G118013 NA non-coding downstream 599383 18466368 ~ 18730812 (+)
G118043 LOC104945943 non-coding downstream 807289 18674274 ~ 18676226 (+)
G118285 NA non-coding downstream 1589157 19456142 ~ 19456983 (+)
G117786 LOC101064881,LOC103134930,LOC106938822,LOC106933658,LOC103469853,LOC105937727 other upstream 771082 17068212 ~ 17069670 (+)
AMCG00018602 LOC102789415 other upstream 2859047 14954564 ~ 14981705 (+)
G117383 NA other upstream 3052619 14786623 ~ 14788133 (+)
G117379 rplp0,LOC107701857,LOC107654305,LOC107591459 other upstream 3063642 14774115 ~ 14777110 (+)
AMCG00018567 NA other upstream 3428473 14408958 ~ 14412279 (+)
AMCG00018681 NA other downstream 114155 17981140 ~ 17983017 (+)
AMCG00018702 NA other downstream 852221 18719206 ~ 18721343 (+)
AMCG00018712 NA other downstream 960612 18827597 ~ 18840095 (+)
AMCG00018717 trpv4,LOC106585668 other downstream 1027350 18894335 ~ 18908956 (+)
AMCG00018732 NA other downstream 1356183 19223168 ~ 19234351 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_030872 nf2a coding NC_007116.7 CM002889.2 11724428 ~ 11809710 (-)