XLOC_006271 (egln1a)


Basic Information

Item Value
gene id XLOC_006271
gene name egln1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 49175624 ~ 49206713 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012272
AGTGTGTGAAATGTGAATGAAGCGAGGCGGGGCGTATTTATCATGTCACATCTGTAACCACGCCCTCCCTCAGTGACGTCAGAGGTTTGGTTTGTACTTGCGACGTGCAGAACGCAGAGCAACACAGCCACGCGCTTGTAGAGGAGAGCGCAGCGGGATGGAGCGCGCGCGCTGCACGGTGTCGATCCCGACCCCTGTGGTTTATTTAACGGGAATATCTTACCGTGATGAACGGACGCGGTTGTTCGTTCGTATATGTTGATGCTGACGCGTTGTGCGTGAAAGTTGACCGGTGGAAGCACCGGATTTAAAGGGTCGGTGACATGGAGAAGTGCCCGACAGTTCTGGATCCCGACGGGGATAAGCAGTACTGCGAGCTGTGTGGGAAGATGGAAAACCTGCTAAAATGCGGTAGGTGCAGGATCTCATTTTACTGCAGCAAAGAGCATCAAAAGGAGCACTGGAAAAAGCACAAACTCACCTGCAGAGAGGCTGACAAACACAACACTGTGCCCCAAACCCAACAACAGCACCCCAAAACTGCCCATCCAGAGAAAAACAACCTGATCTGCAGCTCAGAAGCTGATCTGAAAGCCAAACCCCACACACAGAAGCTGGCCACCGATTATATAATCCCATGTATGAACAAGCATGGCATCTGTGTGGTGGACAACTTTCTGGGGGAAGACATGGGACTGTCCATTTTGGAGGATGTGAAGGCTCTTCATCAGACGGGTAAATTCACTGACGGTCAGCTGGTCAGTCAGAAAAGTGACTCTTCGAAGGACATACGGGGGGATAAAATCACCTGGATTGAGGGGAAGGAGCCTGGATGCGAGAAAATCTGCTTCTTGATGAGCCGCATGGATGACCTGGTCAGGAATTGCAATGGGAAACTGGGAAACTACATAATTAATGGAAGGACTAAAGCGATGGTGGCGTGTTATCCGGGTAAAGGCACGGGTTATGTGCGCCATGTGGACAACCCGAATGGCGATGGGAGATGCGTCACGTGCATTTATTATCTTAATAAGAATTGGGATGCCAAGGAGCACGGGGGAATGCTGCGGATATTCCCCGAGGGTAAAGCTCAGTTTGCGGACATCGAACCCAAATTTGAccgtttgcttttattctggtctGACAGACGAAACCCTCATGAGGTCCAGCCTGCGTATTCGACAAGatatgcCATTACCGTGTGGTATTTTGATGCTGATGAGCGGGCCAGAGCGAAAGAAAAGTATCTTACAGGTAATCACCTCAATGGCACTGTTCATCCTGAGCCACTTGAACACGTAATTGGACATGATGCAGTCCTGATGgtttgtttttggttttga
>TCONS_00012273
ATGGAGAAGTGCCCGACAGTTCTGGATCCCGACGGGGATAAGCAGTACTGCGAGCTGTGTGGGAAGATGGAAAACCTGCTAAAATGCGGTAGGTGCAGGATCTCATTTTACTGCAGCAAAGAGCATCAAAAGGAGCACTGGAAAAAGCACAAACTCACCTGCAGAGAGGCTGACAAACACAACACTGTGCCCCAAACCCAACAACAGCACCCCAAAACTGCCCATCCAGAGAAAAACAACCTGATCTGCAGCTCAGAAGCTGATCTGAAAGCCAAACCCCACACACAGAAGCTGGCCACCGATTATATAATCCCATGTATGAACAAGCATGGCATCTGTGTGGTGGACAACTTTCTGGGGGAAGACATGGGACTGTCCATTTTGGAGGATGTGAAGGCTCTTCATCAGACGGGTAAATTCACTGACGGTCAGCTGGTCAGTCAGAAAAGTGACTCTTCGAAGGACATACGGGGGGATAAAATCACCTGGATTGAGGGGAAGGAGCCTGGATGCGAGAAAATCTGCTTCTTGATGAGCCGCATGGATGACCTGGTCAGGAATTGCAATGGGAAACTGGGAAACTACATAATTAATGGAAGGACTAAAGCGATGGTGGCGTGTTATCCGGGTAAAGGCACGGGTTATGTGCGCCATGTGGACAACCCGAATGGCGATGGGAGATGCGTCACGTGCATTTATTATCTTAATAAGAATTGGGATGCCAAGGAGCACGGGGGAATGCTGCGGATATTCCCCGAGGGTAAAGCTCAGTTTGCGGACATCGAACCCAAATTTGAccgtttgcttttattctggtctGACAGACGAAACCCTCATGAGGTCCAGCCTGCGTATTCGACAAGatatgcCATTACCGTGTGGTATTTTGATGCTGATGAGCGGGCCAGAGCGAAAGAAAAGTATCTTACAGGTGCTGGTGAAAAAGGCGTGAAGGTGGAGCTAAACAAGCCGTCGGAACCAAGCTAATTAA

Function

symbol description
egln1a Predicted to enable ferrous iron binding activity and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in cellular response to hypoxia and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).

GO:

id name namespace
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0071456 cellular response to hypoxia biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0005506 iron ion binding molecular_function
GO:0031543 peptidyl-proline dioxygenase activity molecular_function
GO:0031545 peptidyl-proline 4-dioxygenase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0008198 ferrous iron binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0031418 L-ascorbic acid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-110408-34 Predicted to enable ferrous iron binding activity and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in cellular response to hypoxia and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).

Ensembl:

ensembl_id ENSDARG00000038996

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012272 False 1343 mRNA 0.50 4 49175624 49206649
TCONS_00012273 True 991 mRNA 0.49 5 49175947 49206713

Neighbor

gene id symbol gene type direction distance location
XLOC_006270 CABZ01005325.1 coding upstream 192824 48982686 ~ 48982800 (+)
XLOC_006268 NA coding upstream 211783 48902167 ~ 48963841 (+)
XLOC_006269 CABZ01030259.1 coding upstream 272565 48902945 ~ 48903059 (+)
XLOC_006267 CU651669.1 coding upstream 333867 48765887 ~ 48841757 (+)
XLOC_006266 NA coding upstream 442591 48729645 ~ 48733033 (+)
XLOC_006272 NA coding downstream 77060 49283773 ~ 49287310 (+)
XLOC_006273 NA coding downstream 101837 49308550 ~ 49313340 (+)
XLOC_006274 ggps1 coding downstream 520620 49727333 ~ 49769372 (+)
XLOC_006275 NA coding downstream 618847 49825560 ~ 49825898 (+)
XLOC_006276 NA coding downstream 658459 49865172 ~ 49867408 (+)
XLOC_006280 NA non-coding downstream 1177201 50383914 ~ 50390410 (+)

Expression


Co-expression Network