nr1h4 (nr1h4,LOC107749275,LOC107686236,LOC107672305,LOC107740216)


Basic Information

Item Value
gene id nr1h4
gene name nr1h4,LOC107749275,LOC107686236,LOC107672305,LOC107740216
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056716.1
NCBI id CM032085.1
chromosome length 26409628
location 24474237 ~ 24488921 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043216758.1
CTTGAAGAGAAACAGATAGATAGTTTAATTAATAACCACTGTCCCGTTTCCCCATGACCCCAGCCGCTCAGTCCAGTTGCTACACAGAATCAGCTTGATGCTTATGATGGCTTCAAATATCGAGACCCGGCTCAGGAGCGCACAGCGTCTGTTAGAGCAATAGAAACAGGATCAAACCCATCATTCACTTCCATCCTGGACTGAGGCATCTTTGGACGCCAAGACTCAACACACAGGCTTCTGAATGAATGAGTGGGTGGGCCATGACGTCAATGTGGTGGGACCTTTACAGATCCCACCCAGTGATGTGTTCCCCCTATCAGAGAGCTCACACTTTTTTGATATTCTGGCAGAGCAGAACAGTCCTTTGCTACAGGACCAGGAGGTCATGCCCTTCACCAGCTATCCCGGCATGCAGTACACCTCGGTGGAGCCCTCCATGTCATCACCATCATACTACTCCAGCCAGCACTGCTACTCACAGTACAATGGAGAGGAGTGGTACTCTCCATCCACCATGTTTGAGATGAGGAAAGGACCGTTGGAGGGAGGCTTTGATAATGAGCTGGACGAGTCTTGCCCAGTTGTTCCAACCATCTGTAAAAGATCCAGACACGCAGCCCACTCTGGAAGGAACAAAGGAGAGGAACTGTGTGTGGTCTGTGGAGATAAAGCATCAGGGTATCACTACAATGCACTCACATGTGAAGGATGTAAAGGTTTCTTCAGAAGGAGTATTACAAAGAAtgctgtatataaatgtaagagTGGAGGAAACTGTGAGATGGACATGTACATGCGCAGAAAATGCCAAGAATGTCGACTCAGAAAGTGCAAAGAGATGGGCATGTTGGCAGAGTGCTTATTAACTGAAATCCAGTGCAAATCCAAAAGactgaggaaaaacacaaaGGCCTCATCTGACGAAAGTATAGGGGATGATGTTGGTGATAGTAGAGACGCTAAACAAATTGTATCTACCACTAAACAGTCCAAGGAGAATATAGAACTGAGCCAAGACCAACAGGCTTTAATAAGTTATATAGTTGATGCTCACAACAAACATCGCATCCCTCAGGATATGGCGAAAAAACTGCTACAAGAGCAATTCAACACAGAAGAAAACTTCCTTCTGCTGACCGAAATGGCAACTAGCCACGTTCAGGTGCTGGTTgagttcacaaaaaatatacCAGGCTTTCAATCTCTGGACCACGAAGATCAGATCGCTTTATTAAAAGGTTCCGCTGTAGAGGCAATGTTCCTGCGCTCAGCACAGGTTTTCTCCAAGAAACTGCCCAATGGACACACAGAGGTGCTAGAGGACAGGATCAGAAGGAGTGGCATATCTGAAGAATTTATCACACCCATGTTTAACTTCTATAAAAGCATTGGGGAGCTGCAGATGATGCAAGAGGAGCATGCTCTCCTTACTGCTATCACGATCCTCTCACCAGACAGACCATACGTAAAGGACCAGCAGGCGGTGGAGCGTCTGCAGGAGCCCATGTTGGAGGTGCTGAGGAAGGTCTGTAAACTACAGCACCCCCACGAGCCCCAGCACTTTGCTCGGCTTCTCGGCCGTCTGACTGAGCTTCGTACCCTCAACCACCACCACGCAGAAATGCTGGAGTCATGGCGTATGAGCGATCACAAGTTCACCCCCCTCCTCTGTGAGATCTGGGACGTTCAGTGACTTCAGAAGTGCTACAGACTTTTACTAAGCTGCCAAAGAGAGGAGTTTACACACTTTTTAGAGAAGTGGACTGTTAAactatgtaatgtaaatgtaatatattgacGAGGTTCACGTAAAAGAGGAAATAAGAAGATTTAAGACATTATCAGCTCTTTAAAAAAGGACTGATGTAcgcattttgatattttaatgccTTTGTAAATGTTTACCTGGCCTTTGCAACCTTGGCACATTGGATTGTTTAAAATCTGCTTTCCTTTATCTGAGGATTTTGtggctttttacattttatgtctgtttttgttttgtgtaattctaaatattttaatgttctaTTAATATTAAGGTTCTGACTGACCTGTGGTCactcttttcacttttttcgAGAATTATGTAACCATACTGTTCATCATCCGAACCGTTTttaagaaatttagcattacatcacttgttcacCTCAGCAGTGATTGATgttcaaaaacatcacaataatccacaaggaATGCATCCATCCACCAATCAACATCTTGTcaagtagaaaaaaagaaacgtatgtaagaaacaaatatacataatttgGACGTaattttaaaccattgcttccaGCTAACGTTAAAATACCttgatgtatttgtttcttacaaacatgcagcttttcacttcatgaGATGGACtgttgtgtggattacttgtagattattgtgatgtttttagcagctgtttagactctcattctgacggcacccattcaattCAGAGGATCTACTGGAaggcaagtgatgtaatgctcaATTTCTCTAttccaataaagaaacaaactcatctagatcttg
>XM_043216759.1
AGCTCATGTTTAACATGCTGATATGAAGCCTCTCGCCGGTTTGTACTACTGTTTGATGGCCTTATCTCTACATCTAGCTTTTATGATTTGATGTGTGGTTCTAAAACGCCGCTCAGTCCAGTTGCTACACAGAATCAGCTTGATGCTTATGATGGCTTCAAATATCGAGACCCGGCTCAGGAGCGCACAGCGTCTGTTAGAGCAATAGAAACAGGATCAAACCCATCATTCACTTCCATCCTGGACTGAGGCATCTTTGGACGCCAAGACTCAACACACAGGCTTCTGAATGAATGAGTGGGTGGGCCATGACGTCAATGTGGTGGGACCTTTACAGATCCCACCCAGTGATGTGTTCCCCCTATCAGAGAGCTCACACTTTTTTGATATTCTGGCAGAGCAGAACAGTCCTTTGCTACAGGACCAGGAGGTCATGCCCTTCACCAGCTATCCCGGCATGCAGTACACCTCGGTGGAGCCCTCCATGTCATCACCATCATACTACTCCAGCCAGCACTGCTACTCACAGTACAATGGAGAGGAGTGGTACTCTCCATCCACCATGTTTGAGATGAGGAAAGGACCGTTGGAGGGAGGCTTTGATAATGAGCTGGACGAGTCTTGCCCAGTTGTTCCAACCATCTGTAAAAGATCCAGACACGCAGCCCACTCTGGAAGGAACAAAGGAGAGGAACTGTGTGTGGTCTGTGGAGATAAAGCATCAGGGTATCACTACAATGCACTCACATGTGAAGGATGTAAAGGTTTCTTCAGAAGGAGTATTACAAAGAAtgctgtatataaatgtaagagTGGAGGAAACTGTGAGATGGACATGTACATGCGCAGAAAATGCCAAGAATGTCGACTCAGAAAGTGCAAAGAGATGGGCATGTTGGCAGAGTGCTTATTAACTGAAATCCAGTGCAAATCCAAAAGactgaggaaaaacacaaaGGCCTCATCTGACGAAAGTATAGGGGATGATGTTGGTGATAGTAGAGACGCTAAACAAATTGTATCTACCACTAAACAGTCCAAGGAGAATATAGAACTGAGCCAAGACCAACAGGCTTTAATAAGTTATATAGTTGATGCTCACAACAAACATCGCATCCCTCAGGATATGGCGAAAAAACTGCTACAAGAGCAATTCAACACAGAAGAAAACTTCCTTCTGCTGACCGAAATGGCAACTAGCCACGTTCAGGTGCTGGTTgagttcacaaaaaatatacCAGGCTTTCAATCTCTGGACCACGAAGATCAGATCGCTTTATTAAAAGGTTCCGCTGTAGAGGCAATGTTCCTGCGCTCAGCACAGGTTTTCTCCAAGAAACTGCCCAATGGACACACAGAGGTGCTAGAGGACAGGATCAGAAGGAGTGGCATATCTGAAGAATTTATCACACCCATGTTTAACTTCTATAAAAGCATTGGGGAGCTGCAGATGATGCAAGAGGAGCATGCTCTCCTTACTGCTATCACGATCCTCTCACCAGACAGACCATACGTAAAGGACCAGCAGGCGGTGGAGCGTCTGCAGGAGCCCATGTTGGAGGTGCTGAGGAAGGTCTGTAAACTACAGCACCCCCACGAGCCCCAGCACTTTGCTCGGCTTCTCGGCCGTCTGACTGAGCTTCGTACCCTCAACCACCACCACGCAGAAATGCTGGAGTCATGGCGTATGAGCGATCACAAGTTCACCCCCCTCCTCTGTGAGATCTGGGACGTTCAGTGACTTCAGAAGTGCTACAGACTTTTACTAAGCTGCCAAAGAGAGGAGTTTACACACTTTTTAGAGAAGTGGACTGTTAAactatgtaatgtaaatgtaatatattgacGAGGTTCACGTAAAAGAGGAAATAAGAAGATTTAAGACATTATCAGCTCTTTAAAAAAGGACTGATGTAcgcattttgatattttaatgccTTTGTAAATGTTTACCTGGCCTTTGCAACCTTGGCACATTGGATTGTTTAAAATCTGCTTTCCTTTATCTGAGGATTTTGtggctttttacattttatgtctgtttttgttttgtgtaattctaaatattttaatgttctaTTAATATTAAGGTTCTGACTGACCTGTGGTCactcttttcacttttttcgAGAATTATGTAACCATACTGTTCATCATCCGAACCGTTTttaagaaatttagcattacatcacttgttcacCTCAGCAGTGATTGATgttcaaaaacatcacaataatccacaaggaATGCATCCATCCACCAATCAACATCTTGTcaagtagaaaaaaagaaacgtatgtaagaaacaaatatacataatttgGACGTaattttaaaccattgcttccaGCTAACGTTAAAATACCttgatgtatttgtttcttacaaacatgcagcttttcacttcatgaGATGGACtgttgtgtggattacttgtagattattgtgatgtttttagcagctgtttagactctcattctgacggcacccattcaattCAGAGGATCTACTGGAaggcaagtgatgtaatgctcaATTTCTCTAttccaataaagaaacaaactcatctagatcttg
>XM_043216760.1
TGCTATCTTTGCCACGGCtggtaatgaaataaaacaatgagtCAGAAACTATGAAAAAAGTGAAGCAAATTATCATTAGCAGACGTGAAACTGTCACCTTTAATTTTACAACCCCCGCATCAGCATGTTTTGTCCTAGACTACATATATAAATCTGTATCGATCCTACCTGTAATAAGACAGGGGATTGTGACTGTCAGGTTAATGAGCAACTATAGCAACCTTTGTTCACACTAGCACTTATGTATGAAGTATGAAGGTGTTGAAGAACAGTAATTCTCTGTGAAAAGAGACATATAGACACatgctgaagagctgaaggaaCAGTTGGATGGTTAGGTATCAGAACGGCTAACGATCATCTGCACCCTTACTGGGTCACACTGAAATGGCCATGGTTCAGGACAAGGCTTCAGATATTCTGGCAGAGCAGAACAGTCCTTTGCTACAGGACCAGGAGGTCATGCCCTTCACCAGCTATCCCGGCATGCAGTACACCTCGGTGGAGCCCTCCATGTCATCACCATCATACTACTCCAGCCAGCACTGCTACTCACAGTACAATGGAGAGGAGTGGTACTCTCCATCCACCATGTTTGAGATGAGGAAAGGACCGTTGGAGGGAGGCTTTGATAATGAGCTGGACGAGTCTTGCCCAGTTGTTCCAACCATCTGTAAAAGATCCAGACACGCAGCCCACTCTGGAAGGAACAAAGGAGAGGAACTGTGTGTGGTCTGTGGAGATAAAGCATCAGGGTATCACTACAATGCACTCACATGTGAAGGATGTAAAGGTTTCTTCAGAAGGAGTATTACAAAGAAtgctgtatataaatgtaagagTGGAGGAAACTGTGAGATGGACATGTACATGCGCAGAAAATGCCAAGAATGTCGACTCAGAAAGTGCAAAGAGATGGGCATGTTGGCAGAGTGCTTATTAACTGAAATCCAGTGCAAATCCAAAAGactgaggaaaaacacaaaGGCCTCATCTGACGAAAGTATAGGGGATGATGTTGGTGATAGTAGAGACGCTAAACAAATTGTATCTACCACTAAACAGTCCAAGGAGAATATAGAACTGAGCCAAGACCAACAGGCTTTAATAAGTTATATAGTTGATGCTCACAACAAACATCGCATCCCTCAGGATATGGCGAAAAAACTGCTACAAGAGCAATTCAACACAGAAGAAAACTTCCTTCTGCTGACCGAAATGGCAACTAGCCACGTTCAGGTGCTGGTTgagttcacaaaaaatatacCAGGCTTTCAATCTCTGGACCACGAAGATCAGATCGCTTTATTAAAAGGTTCCGCTGTAGAGGCAATGTTCCTGCGCTCAGCACAGGTTTTCTCCAAGAAACTGCCCAATGGACACACAGAGGTGCTAGAGGACAGGATCAGAAGGAGTGGCATATCTGAAGAATTTATCACACCCATGTTTAACTTCTATAAAAGCATTGGGGAGCTGCAGATGATGCAAGAGGAGCATGCTCTCCTTACTGCTATCACGATCCTCTCACCAGACAGACCATACGTAAAGGACCAGCAGGCGGTGGAGCGTCTGCAGGAGCCCATGTTGGAGGTGCTGAGGAAGGTCTGTAAACTACAGCACCCCCACGAGCCCCAGCACTTTGCTCGGCTTCTCGGCCGTCTGACTGAGCTTCGTACCCTCAACCACCACCACGCAGAAATGCTGGAGTCATGGCGTATGAGCGATCACAAGTTCACCCCCCTCCTCTGTGAGATCTGGGACGTTCAGTGACTTCAGAAGTGCTACAGACTTTTACTAAGCTGCCAAAGAGAGGAGTTTACACACTTTTTAGAGAAGTGGACTGTTAAactatgtaatgtaaatgtaatatattgacGAGGTTCACGTAAAAGAGGAAATAAGAAGATTTAAGACATTATCAGCTCTTTAAAAAAGGACTGATGTAcgcattttgatattttaatgccTTTGTAAATGTTTACCTGGCCTTTGCAACCTTGGCACATTGGATTGTTTAAAATCTGCTTTCCTTTATCTGAGGATTTTGtggctttttacattttatgtctgtttttgttttgtgtaattctaaatattttaatgttctaTTAATATTAAGGTTCTGACTGACCTGTGGTCactcttttcacttttttcgAGAATTATGTAACCATACTGTTCATCATCCGAACCGTTTttaagaaatttagcattacatcacttgttcacCTCAGCAGTGATTGATgttcaaaaacatcacaataatccacaaggaATGCATCCATCCACCAATCAACATCTTGTcaagtagaaaaaaagaaacgtatgtaagaaacaaatatacataatttgGACGTaattttaaaccattgcttccaGCTAACGTTAAAATACCttgatgtatttgtttcttacaaacatgcagcttttcacttcatgaGATGGACtgttgtgtggattacttgtagattattgtgatgtttttagcagctgtttagactctcattctgacggcacccattcaattCAGAGGATCTACTGGAaggcaagtgatgtaatgctcaATTTCTCTAttccaataaagaaacaaactcatctagatcttg

Function

symbol description
nr1h4 Enables bile acid binding activity and nuclear receptor activity. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in intestinal bulb and liver. Human ortholog(s) of this gene implicated in extrahepatic cholestasis; hepatocellular carcinoma; and progressive familial intrahepatic cholestasis 5. Orthologous to human NR1H4 (nuclear receptor subfamily 1 group H member 4).

NR:

description
PREDICTED: bile acid receptor isoform X1

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0030522 intracellular receptor signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0032052 bile acid binding molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K08537 NR1H4, FXR; farnesoid X receptor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043216758.1 False 2532 mRNA 0.43 10 24476351 24488921
XM_043216759.1 False 2577 mRNA 0.43 11 24474237 24488921
XM_043216760.1 True 2606 mRNA 0.42 9 24478592 24488921

Neighbor

gene id symbol gene type direction distance location
slc17a8 slc17a8,LOC107553956,LOC107672209,LOC107686235,LOC107583818 coding upstream 1286 24460916 ~ 24472951 (+)
si:dkey-103i16.6 si:dkey-103i16.6,LOC107749280,LOC107664689,LOC107553976,LOC107672161 coding upstream 124080 24338891 ~ 24350157 (+)
si:ch73-62b13.1 si:ch73-62b13.1,LOC107749314,LOC107740436,LOC107672215,LOC107553958,LOC107583921,LOC107664683,LOC108425440 coding upstream 159257 24308176 ~ 24314980 (+)
zgc:153031 zgc:153031,LOC107664682,LOC107583831,LOC107672313,LOC107553959 coding upstream 182778 24287138 ~ 24291459 (+)
cry1b cry1ab,LOC107672239,LOC107553944,LOC107583830 coding upstream 187462 24277282 ~ 24286775 (+)
LOC122322915 LOC107553937,LOC107749305,LOC107686321,LOC107686322,LOC107553936 coding downstream 5012 24493933 ~ 24502864 (+)
LOC122322916 LOC107749305,LOC107686322,LOC107553937,LOC107686321,LOC107553936 coding downstream 23211 24512132 ~ 24522487 (+)
ube2na ube2na,ube2nb,ube2n,LOC105897570,LOC107707098,LOC107658971,LOC106609528 coding downstream 38290 24527211 ~ 24534508 (+)
nudt4a LOC107740279,LOC107672310,LOC107553971,LOC107686239 coding downstream 46375 24535296 ~ 24549380 (+)
eea1 LOC107686240,LOC107583815,LOC107672259,LOC107740258 coding downstream 61511 24550432 ~ 24570221 (+)
G128859 NA non-coding upstream 15303 24458719 ~ 24458934 (+)
G128857 arntl2,LOC107749276,LOC107686234 non-coding upstream 29038 24444502 ~ 24445199 (+)
G128856 NA non-coding upstream 31078 24442373 ~ 24443159 (+)
G128841 NA non-coding upstream 33705 24436038 ~ 24440532 (+)
G128855 NA non-coding upstream 38857 24435074 ~ 24435380 (+)
G128863 si:ch211-219a15.3,LOC107553954,LOC107583920,LOC107740237,LOC107672306,LOC105898028 non-coding downstream 35606 24524527 ~ 24525054 (+)
G129038 NA non-coding downstream 175530 24664451 ~ 24728979 (+)
LOC122362653 NA non-coding downstream 178563 24667484 ~ 24669844 (+)
LOC122362654 NA non-coding downstream 246266 24735187 ~ 24737012 (+)
G129115 mgat4c,LOC107553950,LOC107740326,LOC107672194 non-coding downstream 350141 24839062 ~ 24856231 (+)
G128858 NA other upstream 16677 24449765 ~ 24457560 (+)
cdh13 cdh13,LOC107722459,LOC107684661,LOC107587012,LOC107738387,LOC107666219,LOC107553949 other upstream 737389 23457100 ~ 23736848 (+)
G128367 LOC107722471,LOC107738392,LOC107587041 other upstream 2035558 22434806 ~ 22438679 (+)
LOC122363143 LOC107722468,LOC107587027,LOC107670369,LOC107684651,LOC107738409,LOC107559800,LOC107705337,LOC107658950,LOC107584024,LOC107656390,LOC107718551,LOC107590534 other upstream 2062280 22400944 ~ 22411957 (+)
LOC122362661 zgc:77650,arf5,LOC107599973,LOC107559620,LOC108439765,LOC108439842,LOC107599983,LOC103033491 other upstream 3833178 20634845 ~ 20641059 (+)
LOC122323037 NA other downstream 94924 24583845 ~ 24588337 (+)
kiaa0513 zgc:91860,LOC107583795,LOC107740318,LOC107686269,LOC107738753,LOC107549630 other downstream 805822 25294743 ~ 25309740 (+)
mt2 NA other downstream 857471 25346392 ~ 25348594 (+)
G129424 LOC107738763,LOC107549607,LOC107686336,LOC107742881,LOC107583870 other downstream 1432346 25921267 ~ 26174156 (+)
slc24a1 LOC107596980,LOC107738725,LOC107686291,LOC107672236,LOC107742879,LOC107583763 other downstream 1463409 25952330 ~ 25962581 (+)

Expression


Co-expression Network