XLOC_007274 (gdf9)


Basic Information

Item Value
gene id XLOC_007274
gene name gdf9
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007125.7
NCBI id CM002898.2
chromosome length 52660232
location 22457230 ~ 22464183 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00014357
CTGTCAGGAAAAGGCGACGGAAGTGTAGTTTGGCCGAAGACACCGAGGTTTTCTCCGGGACCGTTCTTAAATAAACCGACGTTATTTATTATGGCGACgctgttttttaaatgtagtgcGCTTTGTTACCTACCCAGATCATTAATTGTCCTCGCAGTTCTCGGACTGTCAATTACATCAAGCTACAACTTTGAAAACGAGTCTGTTGAACCCGACGTGCCCCTTCAACATGGTAATATCCTGAGCCCTTTGTTAAAGGCTTTGTCAGAGCAGAACCCATGGGGAGAGTTTACACACCGAACCAAACCTGACTCCAGATATGTGCGCTACATGAGGAGACTGTACAAACAGTCATCCAAACCCTACAGGAGCCCCGAAGCCTCTCACCTGTACAACACCGCTCGTCTGATCACTCCTAGGGAAGAGTGTCTCAAGCAAAACAGAGAATTCTTCATGCAAGACATTTCCTACAGTCTGAATCGAGTGAGGTCACAAGAACACTTGCTAAAATCCGTCCTGCTGTACTCCTTCGACCACAACCACCTCTCTCCATTCTCATTGCTCTGTTATCTTGACATGAAGGAACAGAAATCCTCCaaggatcagatgtgctccaaccaTCTGGGCATCCAGCACTCGGTCCCCCTGCTCAGCTTCCGCGTCCATCACCGCTGGGTGGAGGTGGACGTGACCTCCTTCCTTCATCCTCTCATTCAGGCCCATAAGAAGGACATCCACCTACTGATCAACCTGACCTGCGTCGAAGATATGATCTCCAGACCTGGAGGCCAGATTCATAAGAGTCCTGTTGAGTTAACTCCCAGATCTCCATCACTCCTTCTCTATCTTAACGACACCAGTGAGGTGGCGTACCAGAGAAGAAGCACACAGGGCAGGATGGTGGATCTGACATCAAACCATTGGGATGGAAAGTCCACATTATGGGAATCGACTTCTCGAAGGCGACGAGGCACCCTAAAGAGTTCAGAAACCAGCATGCCTAAACTCGTCCCCATGTATGAGTTTACGACCGATGATTGTGACCTGTATGATTTCAGAGTGAGCTTCAAAGAGCTCAAACTGGACCATTGGATCATTGAGCCTAAAAAATACAATCCGAGGTACTGCAAGGGATCTTGTCCGAGGAATGTGGGTTTTATGTACGGGTCGCCAATGCACACCATGGTTCAGAACCTCATTTATGAAAAGTTGGACTCTTCTGTGCCCAGACCTACATGCGTACCATCAGAATATAACCCTTTAAGTGTTTTAACCTTTGAGAATGACAAATCCTATGCTTATAAAGAGTATGAGGAGATGATTGCTACTAAATGCGCTTGTCGATAAAATTAATTTGGctggttgaattttttttttttccctattttttgTGATACTACATTGCTTTGTAAAACACTGACCTATTTTTTTTGCACTGGCCATTCTCATTATGAAGATGATTAATGACCACGTGTGTCAGATAATTTGCTGAAATGTTTATTTGACATTACCTTTTTATCTGACTCTGTAATGCTCCAAATATTTGAATGAATTTCGCAATTGAGTTGTTTTGgtgttttcaggttttttttttttttgtaatatagttgTATATGGGGGTATTTAATTGGCTTAAAGGATAATTTTCTACTTTGATGAGAAGTtctgttattttaagttttttttctctttaggtTGGTGGTCTTGTCATGCACTTTCTATTCCTTAAACATGAATTGCAAAATTTTAATACTTCTGGTTCTGGACAGAATATGAAAAGTGTGGTTCTATTGTCTTATCAGAAcacttttacattgttttttaaaacctGGGAATTGCAGACGGTTGTCTCATGGGCAACCTCTCTCTTCTTGATGTCCAGAAAATAAGTTGCCCTAATTGTGGGCAACTTGATATGTGTGTATTAACTGCTTTAAAGAAAGTAATGGATGAGAATGTGTGTCACGTGcctatttatgtaatttatgtcTTTGTAATTTGGTCAGACTGGCTTtggtttcacaaaaaaaagtgtagaggagagaaaaaaaaatcccatatgaaaatataaaataaaaacaaaaaattctgcAAACACA

Function

symbol description
gdf9 Predicted to enable cytokine activity and type I activin receptor binding activity. Acts upstream of or within female sex determination. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in fertilized egg; gonad; and immature gonad. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 14. Orthologous to human GDF9 (growth differentiation factor 9).

GO:

id name namespace
GO:0060395 SMAD protein signal transduction biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0030237 female sex determination biological_process
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0070698 type I activin receptor binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG:

id description
ko04060 Cytokine-cytokine receptor interaction
ko04052 Cytokines and growth factors

ZFIN:

id description
ZDB-GENE-050221-7 Predicted to enable cytokine activity and type I activin receptor binding activity. Acts upstream of or within female sex determination. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in fertilized egg; gonad; and immature gonad. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 14. Orthologous to human GDF9 (growth differentiation factor 9).

Ensembl:

ensembl_id ENSDARG00000003229

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00014357 True 2099 mRNA 0.41 2 22457230 22464183

Neighbor

gene id symbol gene type direction distance location
XLOC_007273 sowahab coding upstream 2345 22447662 ~ 22454885 (+)
XLOC_007272 atp7a coding upstream 13728 22397251 ~ 22443502 (+)
XLOC_007271 atp10b coding upstream 89309 22293787 ~ 22367921 (+)
XLOC_007270 gabrb2a coding upstream 183383 22172047 ~ 22273847 (+)
XLOC_007269 gabra6a coding upstream 288444 22152060 ~ 22168786 (+)
XLOC_007275 nudt22 coding downstream 3489 22467672 ~ 22479480 (+)
XLOC_007276 smyd5 coding downstream 34574 22498757 ~ 22523799 (+)
XLOC_007277 gfra4b coding downstream 127441 22591624 ~ 22708777 (+)
XLOC_007278 BX005043.2 coding downstream 343315 22807498 ~ 22811997 (+)
XLOC_007279 NA coding downstream 376974 22841157 ~ 22959220 (+)
XLOC_007268 NA non-coding upstream 317017 22129096 ~ 22140213 (+)
XLOC_007259 NA non-coding upstream 679394 21777557 ~ 21777836 (+)
XLOC_007255 ndufs8b non-coding upstream 778313 21671107 ~ 21678917 (+)
XLOC_007254 NA non-coding upstream 1163732 21293114 ~ 21293498 (+)
XLOC_007241 NA non-coding upstream 1612190 20841544 ~ 20845040 (+)
XLOC_007293 NA non-coding downstream 1766728 24230911 ~ 24234703 (+)
XLOC_007298 BX005228.1 non-coding downstream 1893217 24357400 ~ 24357517 (+)
XLOC_007300 NA non-coding downstream 2412919 24877102 ~ 24878581 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000000_18605257_18608772 GDF9 coding CI01000000 null 18604535 ~ 18609087 (-)