XLOC_007338 (xiap)


Basic Information

Item Value
gene id XLOC_007338
gene name xiap
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007125.7
NCBI id CM002898.2
chromosome length 52660232
location 28473173 ~ 28483419 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00014451
TTGCCAAATTTCCCACCACTGCCCACTTGGGTGAATTGTGACGTCTCATACTCTACTTCCGTAACgttaaacatttcatttaaatttactatagttgtttttatttttgtttattaatttaatccttCTACTGAAAAAGGTAGTGTCGATTTGACGTTGCTTGGAAATCCTAGTGCAGAGCCCCCAATCGTCTCTCTGTGGCTCTGCCAGTTAACGTTAATGGGATAGCACGAACGTCACGTTGCTAACACTCACCACAGTAAATTCCTGTTTGGGTTGTCACCATTTACGCATCCATCCCTCTGCGCTGCGCTGTCTTGTAATCGTTACTTGCCTTCGACCAAGAACAGAATAAAGTACAGCTTTCCTTTTTTGAAGAACTGCACTGGATATCGTGTTTCCTGACCGAAGAAATTTAGTTACTACAAATATGGCACACTCAACTCATAATGGCGAATTGGAATCTGACAATGTGgcagctgattggtcagtcatgaaGAATCGGGTGAACTCTTTTCAACGTTTTCCATATTCTGAAGACATTTCAGCACAGCGGCTGGCCCGAGCGGGCTTTTACTTCACAGGCGAGGGGGACAGGGTGCAATGTTTCAGCTGCAGTGCCACTGTGCAGAACTGGAACAGAGGTGACACCCCATTGGAGAGACATCAACTGGCATCTCCGGACTGCAGGTTCCTCAGCTGTGCTCATGGTATGAGAAACTCTAATTCGATCCAGAGTCCTGATTACGATGAAGAGGCCGAGAATAGAGAGTTCCTCCTCCGCACGGGAGAGGTGGTGGACGAGTCCATGTATCCTGTTGTACCGCACATGAAGAGTGAAGAAGCGCGACTGAGTACTTTCAACAACTGGCCAGCAGACTCTCCAGTTCGGCCTGAAGACCTGGCAGAAGCAGGGATGTATTACATTGGGATAGACGACAATGTGCAGTGCTTCTGTTGCGGAGGGGGTCTGAGTGGATGGGAGCAAGGCGACGATCCTTGGAGTGAACATGCGAAGTACTACTCAAACTGCTTCTTCTTCTTGGGCCACAATGTGGGCAACGTCCCCCTGACAACACCTAGGCCAAGGGCTAATGTCCACCCTACAGACACTTTTGAGGGGCGTCTTGATAGCTTCAAAGGCAGACAGCATCCCATTGACCCTGAGAGATTGGCCAGAGCTGGTTTCTACAGCACAGGTGAACAAGACCGTGTGATGTGCTTCAGATGTGGAGGAGGAGTAAAGGCATGGATGCCTGATGAAGACCCTTGGGAGGAACATGCCAGACACTATCCAGGTTGCAGTTTCCTTCTGGCAGAAAAAGGAGAAGAATATGTCAGCAGTGTTCAACTGAGATATCCAAAAAGGCCAACTCAGAATGGCTTTTCAAGTCATGAGAGCGGTTCTTCAGCCCAGGCATTAATTCACGGCTCCAGTGACATGTTTGAGAAAGCCGATGACCCAATGACAGAACTTGAGAAACTCCAGAGGGAGAAGCTCTGCAAGGTCTGCATGGACAGTGACATCAGCATCGTCTTCATTCCCTGCGGACACCTGGTCACCTGTCAAAAATGTTCAGCGTCCCTAGACAAGTGTCCCATCTGCTGTGCTACCATCACACAGAAGATAAAGACTTACAATGCCTAAATGACAAAGAAGCCCGCCTTCTGTACGAATCCCTGAAGTTCACTGAAAGTGGCAAAATGTAATCCTCATTCCTACAATTGCACATGTGTAAAATTTGATTTaaggtgtgtgtttgtatatatgtgttgATGTACTAAAttcttataaaatatatatattgttttattttttcattcagaCCTAATAATATTAAGCTGTACATTTGTGTCTGTTTGATCAAGGAAGGGACACActacattaatatttaacttgtaatatattgagaaaattatttttatttgaccaCTTCACACACTATGATTGAGGTTAATAACCGTAGTGCCTTTATGTAGACTTAATACGAATATTATACAGTTTGTTTAATTGACATAATCATGTACCTTGTGTttgcttttattcatttaatattgcTTAAGACTTTTAATCATGTTCAAAGTTGATTAAACTTCACCAgtccaagtttttttttctctcttgatCTTTCTGtatcattttgaataatgttttgttttatcactatGATTATATTAAAAGTAGAATTCTCCATG

Function

symbol description
xiap Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; positive regulation of canonical Wnt signaling pathway; and positive regulation of protein ubiquitination. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis).

GO:

id name namespace
GO:0090263 positive regulation of canonical Wnt signaling pathway biological_process
GO:0090307 mitotic spindle assembly biological_process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0031398 positive regulation of protein ubiquitination biological_process
GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0005876 spindle microtubule cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process molecular_function
GO:0046872 metal ion binding molecular_function
GO:0061630 ubiquitin protein ligase activity molecular_function

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko04064 NF-kappa B signaling pathway
ko04210 Apoptosis
ko04214 Apoptosis - fly
ko04215 Apoptosis - multiple species
ko04217 Necroptosis
ko04510 Focal adhesion
ko04621 NOD-like receptor signaling pathway
ko05200 Pathways in cancer
ko05207 Chemical carcinogenesis - receptor activation
ko05222 Small cell lung cancer
ko05166 Human T-cell leukemia virus 1 infection
ko05145 Toxoplasmosis
ko01524 Platinum drug resistance
ko01002 Peptidases and inhibitors
ko04121 Ubiquitin system
ko03029 Mitochondrial biogenesis

ZFIN:

id description
ZDB-GENE-030825-7 Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; positive regulation of canonical Wnt signaling pathway; and positive regulation of protein ubiquitination. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis).

Ensembl:

ensembl_id ENSDARG00000016143

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00014451 True 2196 mRNA 0.43 6 28473173 28483419

Neighbor

gene id symbol gene type direction distance location
XLOC_007337 psmd10 coding upstream 3929 28464736 ~ 28469244 (+)
XLOC_007335 acsl4a coding upstream 13727 28438947 ~ 28459446 (+)
XLOC_007336 NA coding upstream 28193 28444739 ~ 28444980 (+)
XLOC_007334 pin4 coding upstream 35747 28432737 ~ 28437426 (+)
XLOC_007333 mid2 coding upstream 87608 28281744 ~ 28385565 (+)
XLOC_007339 stag2b coding downstream 2794 28486213 ~ 28527422 (+)
XLOC_007340 hmmr coding downstream 61779 28545198 ~ 28562971 (+)
XLOC_007341 NA coding downstream 84145 28567564 ~ 28660969 (+)
XLOC_007342 NA coding downstream 374530 28857949 ~ 28910287 (+)
XLOC_007343 TENM2 coding downstream 717353 29200772 ~ 29760015 (+)
XLOC_007332 NA non-coding upstream 391101 28081081 ~ 28082072 (+)
XLOC_007331 NA non-coding upstream 639412 27720386 ~ 27833761 (+)
XLOC_007329 NA non-coding upstream 757749 27564398 ~ 27715424 (+)
XLOC_007347 NA non-coding downstream 1595695 30079114 ~ 30243127 (+)
XLOC_007353 NA non-coding downstream 1970681 30454100 ~ 30455836 (+)
XLOC_007357 NA non-coding downstream 2141927 30625346 ~ 30627451 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000000_14841466_14845039 NA coding CI01000000 null 14841458 ~ 14845709 (-)