akr1a1 (akr1a1,akr1a1b,LOC107731642)


Basic Information

Item Value
gene id akr1a1
gene name akr1a1,akr1a1b,LOC107731642
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035909.1
NCBI id CM008312.1
chromosome length 44161018
location 42139364 ~ 42151948 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007248169.3
TCTGTTTAactgtgtaaagtgtgttaaaTGTGAGTGAATTAGGCAGCCGGAGTTCAGCCGGACTGGAGAAATGCAGCTGCAGCTGCTCAGATTTTCTCTTCTCTGTGTTTATCACTCCTGCAGATCTCACCGCCGCAGCTGGGTTCACAAAGCAAGCATGAGTGATTTTGCAGTCCTCAACACTGGCCGAAAGATGCCCCTTGTTGGACTAGGAACGTGGAAAAGTGAACCTGGAAAAgtAAAGCAAGCAGTGATCTGGGCACTTCAGTCTGGCTATAGACACATTGACTGTGCTGCCATCTACGGAAATGAGCCAGAAATTGGTGAAGCTTTGCAGGAGATGTTGGGGCCTGATAAAGCTTTAAGGCGAGAGGACGTATTTGTTACCTCTAAGTTGTGGAATACGCGGCACCATGCAGAGGATGTGGAGCCTGCCCTGCTCAAGAGCTTGAAGGAGCTGAAGCTGGAATACCtggacctctacctcattcATTGGCCTTATGCTTTCCAacGTGGGGATGTTGCTTTTCCAAAAAAGGAAGATGGGACCTTACTGTATGATGATATTGACTACAAAGTGACATGGGCTGCCATGGAGAAACTTGTTGAAAAGGGACTTGTGAGGGCCATCGGAATCTCAAACTTTAACAGCCGACAGATTGATGACATCCTATCAGTGGCCAGTATAAAGCCTACTGTTTTGCAGGTGGAAGGGCACCCATACCTGGCACAGGTGGAGCTGCTTGCTCACTGCAGGGAACGGGGAATAGTGATGACTGCCTACAGTCCACTGGGTTCTCCAGACCGAGCCTGGAAAAGACCAGATGAGCCAGTTTTGTTACAGGAACCAGTCATTGCTTCTTTGGCCAAGAAGTACAAGAAATCTGTGGCACAGATTATAATcaggtggCAAACCCAGCGAGGAGTAGTGACGATCCCAAAGAGCGTTACAGAGTCTCgcataaaagaaaatatacagATCTTTGACTTCACACTGGAGCCTGAGGAAATGAACAGCATTACAGCATTGAATAAAGGCTGGCGTTACATAGTGCCAACAATTactgttgaTGACAAGCCCTTACCAAGAGATGCAGGACACCCTCACTACCCCTTCAATGATGCATATTAACACATCATGCTCCAATAATCTGTGCCTTCCAACCCACTTCAATTAAAACCCACTTCTGTATGCTGatcacaataaatgtttttcttacTGATTGGA
>XM_007248171.3
AGTGTTGAGCTCGTGTGGGACTTTTAATTTGGTGGTCTGAAACGATGGTATTCCCAAACCGGAAATGTTTTCGTAACGTCACCAGTGAGatataaaaattaaagattttaaagatttaatgtttagctgtttttgtgGAGAATACTGAGGATACCGTTCTGCCCTGCTCGATATATAAATACCGTTCACAAAGCAAGCATGAGTGATTTTGCAGTCCTCAACACTGGCCGAAAGATGCCCCTTGTTGGACTAGGAACGTGGAAAAGTGAACCTGGAAAAgtAAAGCAAGCAGTGATCTGGGCACTTCAGTCTGGCTATAGACACATTGACTGTGCTGCCATCTACGGAAATGAGCCAGAAATTGGTGAAGCTTTGCAGGAGATGTTGGGGCCTGATAAAGCTTTAAGGCGAGAGGACGTATTTGTTACCTCTAAGTTGTGGAATACGCGGCACCATGCAGAGGATGTGGAGCCTGCCCTGCTCAAGAGCTTGAAGGAGCTGAAGCTGGAATACCtggacctctacctcattcATTGGCCTTATGCTTTCCAacGTGGGGATGTTGCTTTTCCAAAAAAGGAAGATGGGACCTTACTGTATGATGATATTGACTACAAAGTGACATGGGCTGCCATGGAGAAACTTGTTGAAAAGGGACTTGTGAGGGCCATCGGAATCTCAAACTTTAACAGCCGACAGATTGATGACATCCTATCAGTGGCCAGTATAAAGCCTACTGTTTTGCAGGTGGAAGGGCACCCATACCTGGCACAGGTGGAGCTGCTTGCTCACTGCAGGGAACGGGGAATAGTGATGACTGCCTACAGTCCACTGGGTTCTCCAGACCGAGCCTGGAAAAGACCAGATGAGCCAGTTTTGTTACAGGAACCAGTCATTGCTTCTTTGGCCAAGAAGTACAAGAAATCTGTGGCACAGATTATAATcaggtggCAAACCCAGCGAGGAGTAGTGACGATCCCAAAGAGCGTTACAGAGTCTCgcataaaagaaaatatacagATCTTTGACTTCACACTGGAGCCTGAGGAAATGAACAGCATTACAGCATTGAATAAAGGCTGGCGTTACATAGTGCCAACAATTactgttgaTGACAAGCCCTTACCAAGAGATGCAGGACACCCTCACTACCCCTTCAATGATGCATATTAACACATCATGCTCCAATAATCTGTGCCTTCCAACCCACTTCAATTAAAACCCACTTCTGTATGCTGatcacaataaatgtttttcttacTGATTGGA
>XM_007248172.2
gtatgtaaactccaccagaagcatgaagCAGAAGTTGCAGTCTTAGTATGTGAATAAAAAGTCTGTTCACAAAGCAAGCATGAGTGATTTTGCAGTCCTCAACACTGGCCGAAAGATGCCCCTTGTTGGACTAGGAACGTGGAAAAGTGAACCTGGAAAAgtAAAGCAAGCAGTGATCTGGGCACTTCAGTCTGGCTATAGACACATTGACTGTGCTGCCATCTACGGAAATGAGCCAGAAATTGGTGAAGCTTTGCAGGAGATGTTGGGGCCTGATAAAGCTTTAAGGCGAGAGGACGTATTTGTTACCTCTAAGTTGTGGAATACGCGGCACCATGCAGAGGATGTGGAGCCTGCCCTGCTCAAGAGCTTGAAGGAGCTGAAGCTGGAATACCtggacctctacctcattcATTGGCCTTATGCTTTCCAacGTGGGGATGTTGCTTTTCCAAAAAAGGAAGATGGGACCTTACTGTATGATGATATTGACTACAAAGTGACATGGGCTGCCATGGAGAAACTTGTTGAAAAGGGACTTGTGAGGGCCATCGGAATCTCAAACTTTAACAGCCGACAGATTGATGACATCCTATCAGTGGCCAGTATAAAGCCTACTGTTTTGCAGGTGGAAGGGCACCCATACCTGGCACAGGTGGAGCTGCTTGCTCACTGCAGGGAACGGGGAATAGTGATGACTGCCTACAGTCCACTGGGTTCTCCAGACCGAGCCTGGAAAAGACCAGATGAGCCAGTTTTGTTACAGGAACCAGTCATTGCTTCTTTGGCCAAGAAGTACAAGAAATCTGTGGCACAGATTATAATcaggtggCAAACCCAGCGAGGAGTAGTGACGATCCCAAAGAGCGTTACAGAGTCTCgcataaaagaaaatatacagATCTTTGACTTCACACTGGAGCCTGAGGAAATGAACAGCATTACAGCATTGAATAAAGGCTGGCGTTACATAGTGCCAACAATTactgttgaTGACAAGCCCTTACCAAGAGATGCAGGACACCCTCACTACCCCTTCAATGATGCATATTAACACATCATGCTCCAATAATCTGTGCCTTCCAACCCACTTCAATTAAAACCCACTTCTGTATGCTGatcacaataaatgtttttcttacTGATTGGA
>XM_007248173.3
ACTGCACTCGATCACAACTCGCCTTCCAgcagaggagagaggaggaagagggaaAATGAAATATGGCTGCCCACTGCAGAAATTACAGTTACatggagaagagaaaagaaaagagacaaaacaGTATAGGTTCACAAAGCAAGCATGAGTGATTTTGCAGTCCTCAACACTGGCCGAAAGATGCCCCTTGTTGGACTAGGAACGTGGAAAAGTGAACCTGGAAAAgtAAAGCAAGCAGTGATCTGGGCACTTCAGTCTGGCTATAGACACATTGACTGTGCTGCCATCTACGGAAATGAGCCAGAAATTGGTGAAGCTTTGCAGGAGATGTTGGGGCCTGATAAAGCTTTAAGGCGAGAGGACGTATTTGTTACCTCTAAGTTGTGGAATACGCGGCACCATGCAGAGGATGTGGAGCCTGCCCTGCTCAAGAGCTTGAAGGAGCTGAAGCTGGAATACCtggacctctacctcattcATTGGCCTTATGCTTTCCAacGTGGGGATGTTGCTTTTCCAAAAAAGGAAGATGGGACCTTACTGTATGATGATATTGACTACAAAGTGACATGGGCTGCCATGGAGAAACTTGTTGAAAAGGGACTTGTGAGGGCCATCGGAATCTCAAACTTTAACAGCCGACAGATTGATGACATCCTATCAGTGGCCAGTATAAAGCCTACTGTTTTGCAGGTGGAAGGGCACCCATACCTGGCACAGGTGGAGCTGCTTGCTCACTGCAGGGAACGGGGAATAGTGATGACTGCCTACAGTCCACTGGGTTCTCCAGACCGAGCCTGGAAAAGACCAGATGAGCCAGTTTTGTTACAGGAACCAGTCATTGCTTCTTTGGCCAAGAAGTACAAGAAATCTGTGGCACAGATTATAATcaggtggCAAACCCAGCGAGGAGTAGTGACGATCCCAAAGAGCGTTACAGAGTCTCgcataaaagaaaatatacagATCTTTGACTTCACACTGGAGCCTGAGGAAATGAACAGCATTACAGCATTGAATAAAGGCTGGCGTTACATAGTGCCAACAATTactgttgaTGACAAGCCCTTACCAAGAGATGCAGGACACCCTCACTACCCCTTCAATGATGCATATTAACACATCATGCTCCAATAATCTGTGCCTTCCAACCCACTTCAATTAAAACCCACTTCTGTATGCTGatcacaataaatgtttttcttacTGATTGGA

Function

symbol description
akr1a1b Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in cellular detoxification of aldehyde. Predicted to be located in apical plasma membrane. Predicted to be active in cytosol. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
akr1a1 Enables L-glucuronate reductase activity and glucuronolactone reductase activity. Involved in daunorubicin metabolic process and doxorubicin metabolic process. Located in extracellular exosome. Biomarker of breast cancer and lung adenocarcinoma.

NR:

description
PREDICTED: alcohol dehydrogenase [NADP(+)] isoform X1

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0047939 L-glucuronate reductase activity molecular_function
GO:0004032 alditol molecular_function

KEGG:

id description
K00002 AKR1A1, adh; alcohol dehydrogenase (NADP+)

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007248169.3 False 1228 mRNA 0.47 9 42139364 42142563
XM_007248171.3 True 1269 mRNA 0.45 9 42139364 42142774
XM_007248172.2 False 1150 mRNA 0.46 9 42139364 42142940
XM_007248173.3 False 1215 mRNA 0.46 9 42139364 42151948

Neighbor

gene id symbol gene type direction distance location
nasp nasp,LOC107551040,LOC107594614 coding downstream 1479 42131577 ~ 42137885 (-)
tmem69 tmem69,LOC107579605 coding downstream 53537 42083217 ~ 42085827 (-)
mast2 mast2 coding downstream 57492 41880968 ~ 42081872 (-)
LOC111193790 NA coding downstream 557347 41581833 ~ 41582017 (-)
tspan1 NA coding downstream 753723 41371036 ~ 41385641 (-)
LOC103030126 LOC103030126,LOC108440237,LOC108271568,LOC107692395 coding upstream 124317 42276265 ~ 42335124 (-)
LOC103033504 NA coding upstream 209788 42361736 ~ 42381697 (-)
LOC107197605 NA coding upstream 500585 42652533 ~ 42656081 (-)
kank4 kank4,LOC107731645,LOC107704518,LOC107692389,LOC107556542,LOC107591186 coding upstream 506010 42657958 ~ 42728407 (-)
dock7 dock7 coding upstream 593672 42745620 ~ 42826931 (-)
G117578 NA non-coding downstream 26305 42097731 ~ 42113059 (-)
G117569 NA non-coding downstream 75356 42063212 ~ 42064008 (-)
G117567 NA non-coding downstream 119834 42016758 ~ 42019530 (-)
G117496 NA non-coding downstream 337452 41800777 ~ 41801912 (-)
LOC111193695 NA non-coding downstream 653140 41461930 ~ 41486224 (-)
G117623 NA non-coding upstream 64510 42216458 ~ 42217016 (-)
G117660 NA non-coding upstream 198172 42350120 ~ 42351195 (-)
G117662 NA non-coding upstream 216557 42368505 ~ 42436537 (-)
G117811 NA non-coding upstream 1074606 43226554 ~ 43232574 (-)
G117954 NA non-coding upstream 1286174 43438122 ~ 43438335 (-)
LOC103041916 LOC107758363,LOC107684070,LOC107692412 other downstream 1121550 40816133 ~ 41017814 (-)
LOC103034527 NA other downstream 1369682 40731296 ~ 40769682 (-)
LOC103040080 LOC108440156 other downstream 1775404 40360319 ~ 40363960 (-)
LOC103028549 NA other downstream 2848336 39284217 ~ 39291028 (-)
LOC103032356 LOC108441420,LOC108272184,LOC107582737,LOC107726519 other downstream 3175670 38953162 ~ 38963694 (-)

Expression


Co-expression Network