pcsk1 (pcsk1,LOC107739678)


Basic Information

Item Value
gene id pcsk1
gene name pcsk1,LOC107739678
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035910.1
NCBI id CM008313.1
chromosome length 38842236
location 35671315 ~ 35699103 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007253958.3
ctctctctctctctctctctctctctctctctctctcactggtaTCTTTCCACGCCTCTCCACGAGCCTACATGCCACAGTCACGAGGAGCGGACCTGATCTCTCTTTCCTGATAATAATATTGATCTGCTCTCTGgtttgatcatttattttttatttctgtattgaGTTGGTATTTCTGTATCTCGCGTCCCGCGCGCCCCGGACTCCGTGCGCGCCCCCGTTTCTCCTCGCGCTGCTCTTCGCTCTGAAATGGCAGTAAGATGTCCTGCTGCGGTGTTTCTCGGCGCTCTCGCGGTTCTCTGCGCGCTGTCTTCCCCAGGAGTGAACGCTTTGGACCGGCAGTACCTCAACGAGTGGGCCGTGGAGATCCCCGGAGGAACGGACGCTGCGCAGTCGATAGCCAACGAGCTCGGCTACGAACTGGTCAGACAGattGGGGCGCTACAAAACCATTATTTATTCAAACATCAGAGTCATCCTAGCAGGACCAAGAGGAGTGCAGACCACATCACCAAGAGGCTGTCAGAAGACGACAGGGTATCGTGGGCGGAGCAGCAGTATGAGAAGCAGAGAAGTAAGCGAGCTCCTTTAGGGGCTGATTGTAAAGAATGCTCAGTGGACAAACTCTTCGATGATCCCATGTGGAACCAGCAGTGGTACCTGCAAGACACGCGGACGTCTCCGTCTCTGCCGAAGCTGGACCTGCACGTGATCCCGGTGTGGAAGAAGGGGATCACGGGTAAAGGCGTGGTCATCACCGTGCTGGACGACGGCCTGGAGTGGAACCACACCGACATCTACCCCAATTACgATCCTGCAGCCAGTTACGATTTCAACGACAACGACCCCGATCCTTTCCCCAGATACGACTCCACCAATGAGAACAAGCACGGGACAAGGTGTGCAGGTGAGATTGCCATGCAGGCGGACAACAACAAATGTGGAGTCGGGGTGGCTTACAACTCTAAGGTTGGAGGGATCCGGATGCTGGATGGCATTGTGACGGACGCCATAGAGGCCAGCTCTATAGGGTTTAACCCGGACCACGTGGACATCTACAGTGCCAGCTGGGGTCCTAATGATGACGGGAAAACAGTGGAGGGTCCTGGTCGTCTGGCTCAGAAAGCCTTCGAGTACGGCATCCAGAAGGGACGTGGTGGAAAGGGCTCTATCTTCGTCTGGGCGTCGGGTAACGGCGGGCGGCAGGGTGATAACTGCGACTGTGACGGCTACACAGACAGCATCTACACCATCTCCATCAGCAGTGCGTCACAGCAGGGCCTGTCCCCGTGGTACGCAGAGAAATGCTCATCCACCCTGGCCACGGCCTACAGCAGCGGAGACTACACCGACCAGAGGATCACCAGTGCTGACTTGCACAATGAATGCACCGAGACACACACCGGAACATCTGCCTCTGCCCCGCTGGCAGCTGGGATCTTTGCCCTGGCTTTGGAACAGAATCCGGATCTGACCTGGAGGGATCTTCAGCATATAGTGGTGTGGACGTCTGAGTTCGACCCGCTGGCCAATAACCCCGGCTGGAAGAGGAACGGCGCAGGGCTGATGGTGAACAGCCGCTTCGGTTTCGGCCTGCTGAACGCTAAAGCTCTGGTGGATCTGGCAGATCCCAAAGTGTGGAAGCACGTGCCGGAGAAAAAGCAGTGCATCGTCAGAGATGACAGCTTCCAACCCAGACCTCTAAAAGCAGCGGGGGAGATCAGCATTGAGATTCCCACCAAAGCGTGTGCTGGCCAGACAAACTCTATAGAGTCTCTGGAGCACGTGCAGGTGGAGGCCAGCATTGAGTACACGAGGAGAGGAGACCTACACATCACACTCACTTCACCATCAGGAACTACTACAGTGCTGCTGGCTGAGCGGGAGAGAGACACGTCCTCCAACGGCTTTAGAAACTGGGACTTCATGTCTGTGCACACCTGGGGAGAGAACCCTACTGGCACCTGGACACTGAAAATCACTGACACTtcgGGCCGGATGGAGAATGAGGGGCAGATACTGAGCTGGAAGCTGATTCTCCACGGAACGTCTGAAAAGCCAGAACACATGAAGAAGCCGAGAGTTTACACACCGTACAACGCAGTGCAGAATGACCGCAGAGGAGTGGAACACATGGAGGACATGCTGGAGGAGGCCACTGCCCCTTCCCAAAAAATGGTAAAGTCCCGTCCACCGGCTCCCATTGCTGCCTCCTCTCCTGCCCCGGAGGAGAGGCATGCAGCTGCTCAAGCCGCTTCCACCCAAGACGCAGACCTGATACGCCTCATCCAGTCAGTCTTCGGCCCCATGTCTATAGCTTCCACTGGACGAGCTTCACCAGCGAGGGAAAGGATCCCTCAGCAAAAGCCGTACGAGACCCTGGTGCACCGCAACCCCGAGAGCAGCCTGTACAACCACTACAGAGACAGCTTCTACAGGAACCGGGCCTACCGGCACAGAGACGAGCAGCTGCTGCAGGCCCTGTTCGACATGCTGGATGGAGAACAGCAGTGAATGAGGGGGCGGAGAGAAGAAAGGGGGAGGGAGGGGCCGGGGAGAGGAGTATGGATGAGAAATAGGGGTAAAATAAAGGAGGTTGGGAGGTAAAAGAGAGGTGTTCTCAGCAGCTACAGTCCTCGGGGACCCACCTGCCTGCACAGTTTCTAGTCTCTGAAGTTCAGGACTCTTGAAGTTCTTAAACACAGAGAATAAACACACATAGAGATTTAcactgtttttgcctttttacaAGTGGAAAGTTGTTCAATTTGACACTAGAATGTGGCAATAcactatatatcacaatatagggGTTATGATTACACATACTATAATAGATATACATTTACACAAtacaaaattaactaaaatacaaaattttagtaaaagtgtcaaaatatgaaaaacCTGTCCATTCCAATCCAGTGTATTTTAATAGATTTGGGTATTAAATTTTAAACTTCCAATCTACTTTAAATCCTTAAGTCCTTACTGGACTGATAAGAGTGGTAATATTATAAGTAAACAGCCAAAAGAAGGGTTTAAttctctattccaccttaaataatgtagCAGTGTCCATTAGCGCTTTTCCACCGACATGGATGAACAACCaatgttgtgccgaattcagcacccccaccagaAAAAGCATCCCCTCTCAGAGCTTATTGCGTATTTCTAAGAAAAGTTAAAgcacttttatcaagaagaccaTGCATGCGGGCTGccaagagagggtgcttttcatggcgggggtgcagatttcggcacTACTATGGTGTTGAATTCAGAACCCCCACAAGAAAAAGCACCCTCTCACCGAATgtacttctaagtaaagttaaagcacttttatcaagaagaccaTGCATACGGGCTTccaagagagggtgcttttatGTCGGGGGGAATTCAGCAACCCCGCCAGAAAAAGCACTCCCTCTTGGAAGAGGCTGAAGGTGACATAACTATTTTTCATTCTTTCCTGGAGGCATTGTAGCTTAAAACAGCCTCTTGGGTactttcattttctaaaaaagttaaagccaagaagagaTACATGCGTGCTtacgagagggggtgcttttcctggcgggggtgctgaattcaggaACCAGGAACGTTCTTTTGTAGCAGGAACCGAAGAATTATAGGTTCTTTAATGCAAACCGTGATGATATTGGTTCACCGCGGCTGTGCAGCGTCCTCTGTTTGTGGAAACGTGGACTGGTTCGTTGAAAAGCACCACGGTTCTTATAAACCAAATGAAGCTGGTTTAAGAACTGGTTTAAAGAgttattttaaggtggaagggaacatttttttaccc

Function

symbol description
pcsk1 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in peptide hormone processing. Predicted to act upstream of or within proteolysis. Predicted to be located in transport vesicle. Predicted to be active in extracellular space; membrane; and neuron projection. Is expressed in several structures, including digestive system; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in obesity and proprotein convertase 1/3 deficiency. Orthologous to human PCSK1 (proprotein convertase subtilisin/kexin type 1).

NR:

description
neuroendocrine convertase 1-like

GO:

id name namespace
GO:0006508 proteolysis biological_process
GO:0004252 serine-type endopeptidase activity molecular_function

KEGG:

id description
K01359 PCSK1; proprotein convertase subtilisin/kexin type 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007253958.3 True 3835 mRNA 0.51 15 35671315 35699103

Neighbor

gene id symbol gene type direction distance location
LOC103029511 NA coding upstream 96611 35568055 ~ 35574704 (+)
LOC103030369 LOC103030369 coding upstream 117024 35543658 ~ 35554291 (+)
LOC103029836 NA coding upstream 135071 35527421 ~ 35536244 (+)
LOC103032475 brd3,brd3a coding upstream 508287 35153924 ~ 35163028 (+)
LOC103036996 rxra coding upstream 536597 34850991 ~ 35134718 (+)
LOC103028363 LOC108437782 coding downstream 7121 35706224 ~ 35711177 (+)
ell2 ell2 coding downstream 18332 35717435 ~ 35747006 (+)
nudt2 nudt2,LOC107661859,LOC107739745,LOC107579639 coding downstream 110402 35809505 ~ 35811707 (+)
LOC103026124 LOC108436592,LOC106955578,LOC104953222 coding downstream 152311 35851414 ~ 35865427 (+)
LOC103043841 LOC103043841 coding downstream 271006 35970109 ~ 35975545 (+)
G127264 NA non-coding upstream 34743 35555911 ~ 35636572 (+)
G127274 NA non-coding upstream 66672 35596326 ~ 35604643 (+)
G127268 NA non-coding upstream 89323 35578546 ~ 35581992 (+)
G127188 NA non-coding upstream 256544 35414319 ~ 35414771 (+)
G127152 NA non-coding upstream 343922 35296361 ~ 35327393 (+)
G127291 NA non-coding downstream 51159 35750262 ~ 35751378 (+)
G127362 NA non-coding downstream 248287 35947390 ~ 35948045 (+)
G127375 NA non-coding downstream 283595 35982698 ~ 35983876 (+)
G127386 NA non-coding downstream 368824 36067927 ~ 36094480 (+)
G127379 NA non-coding downstream 369232 36068335 ~ 36069013 (+)
G127250 NA other upstream 178840 35476122 ~ 35492475 (+)
vav2 vav2 other upstream 206713 35171516 ~ 35464602 (+)
stom stom,LOC107741953,LOC107556938,LOC107708355 other upstream 915186 34718796 ~ 34756129 (+)
LOC103023469 NA other upstream 1188928 34478626 ~ 34482387 (+)
LOC103040215 esm1 other upstream 1206319 34457981 ~ 34464996 (+)
glrx glrx,LOC105014469,LOC107661879 other downstream 56241 35755344 ~ 35761112 (+)
ubap1 ubap1 other downstream 129532 35828635 ~ 35838054 (+)
G127359 NA other downstream 235816 35934919 ~ 35943122 (+)
G127365 NA other downstream 255755 35954858 ~ 35958301 (+)
dtwd2 dtwd2 other downstream 267231 35966334 ~ 35969453 (+)

Expression


Co-expression Network