XLOC_008257 (foxo1a)


Basic Information

Item Value
gene id XLOC_008257
gene name foxo1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 3284416 ~ 3379041 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00016631
TTTTTAGTACACAGACATTCAACAAGAAGCGACAGCAACAGGACTCTCTCTCCCCCCCACACACATAATACAGGACTGGACATTACAAAACTTCACAACAACACCAGTCTGACGCACGCTGCGACTTCGAAATCGTTCCCAATGTAACTCAAGTCAGTTTAACTAAGTATCCGCAGTTCGCTTGTGTTTACAGTTTCGCGTTTCACCTCATATTTTCGCTTGACAATCATATGTGACATTTTAAGAGGCAGACAGTATTGCTGGTACCATGGCTGACGCAGCCCAAAACCAGATGGTGGAGATCGACCCGGACTTCGAGCCGCTGTCCCGGCCCCGCTCCTGCACTTGGCCGCTGCCGCGACCCGAGTTCCCAAACCCCGCCGCCGCGGACTCCAACACTTCATCCCCGGCTCCGTCCGTCAAACAGGAGCCTTCCAGCACCGCGGACTTCATCAACAACCTCAGTCTGCTAGAGGAGAATGAGGACTACCCGGACCAGAAGCCTCTCATGCTCTGCAGCGAGTTCCAGTGCCAGGAGAACTGCATCCACCAGCAGCAGATCCCGAGTCAGCAGCAACAGGTGCCCGTGCTGTCCTCTCCGGTGGCCGCCGCCGCCGCAGCCGCAGCAGCCGCGCAACGCAAAAGCAGCTCGTCTCGGCGCAACGCCTGGGGAAATATGTCGTACGCGGACCTGATCACCAAAGCCATCGAGAGCTCCCCAGAAAAGCGGCTCACCTTGTCTCAGATATACGACTGGATGGTGAAAAGCGTCCCGTATTTTAAAGACAAGGGGGATAGTAACAGCTCCGCGGGCTGGAAGAACTCAATCAGACACAACCTGTCCCTACATAGTAGGTTCATCCGAGTGCAGAATGAGGGGACTGGTAAGAGCTCTTGGTGGATGCTCAACCCTGAGGGTGGGAAAAGTGGAAAGTCTCCTCGACGCCGGGCGGCCTCCATGGACAACAACAGCAAGTTTGCCAAGAGCAGAGGACGAGCGGCAAAGAAAAAGGTACAAGCTGCTTACCAAACCTTTCAGCAGTCActttggctgcatttacactgcatgcttTAAGTGACTTTGTTCCCATTTTTTTCTCCCATCGGGCACAGATCAGGTATGGCCCATGTACTGTACGtctaagc
>TCONS_00016632
TTTTTAGTACACAGACATTCAACAAGAAGCGACAGCAACAGGACTCTCTCTCCCCCCCACACACATAATACAGGACTGGACATTACAAAACTTCACAACAACACCAGTCTGACGCACGCTGCGACTTCGAAATCGTTCCCAATGTAACTCAAGTCAGTTTAACTAAGTATCCGCAGTTCGCTTGTGTTTACAGTTTCGCGTTTCACCTCATATTTTCGCTTGACAATCATATGTGACATTTTAAGAGGCAGACAGTATTGCTGGTACCATGGCTGACGCAGCCCAAAACCAGATGGTGGAGATCGACCCGGACTTCGAGCCGCTGTCCCGGCCCCGCTCCTGCACTTGGCCGCTGCCGCGACCCGAGTTCCCAAACCCCGCCGCCGCGGACTCCAACACTTCATCCCCGGCTCCGTCCGTCAAACAGGAGCCTTCCAGCACCGCGGACTTCATCAACAACCTCAGTCTGCTAGAGGAGAATGAGGACTACCCGGACCAGAAGCCTCTCATGCTCTGCAGCGAGTTCCAGTGCCAGGAGAACTGCATCCACCAGCAGCAGATCCCGAGTCAGCAGCAACAGGTGCCCGTGCTGTCCTCTCCGGTGGCCGCCGCCGCCGCAGCCGCAGCAGCCGCGCAACGCAAAAGCAGCTCGTCTCGGCGCAACGCCTGGGGAAATATGTCGTACGCGGACCTGATCACCAAAGCCATCGAGAGCTCCCCAGAAAAGCGGCTCACCTTGTCTCAGATATACGACTGGATGGTGAAAAGCGTCCCGTATTTTAAAGACAAGGGGGATAGTAACAGCTCCGCGGGCTGGAAGAACTCAATCAGACACAACCTGTCCCTACATAGTAGGTTCATCCGAGTGCAGAATGAGGGGACTGGTAAGAGCTCTTGGTGGATGCTCAACCCTGAGGGTGGGAAAAGTGGAAAGTCTCCTCGACGCCGGGCGGCCTCCATGGACAACAACAGCAAGTTTGCCAAGAGCAGAGGACGAGCGGCAAAGAAAAAGCTGGCTCTTCAGGGTGGCCCCGAGGGTGGCGCGGACAGCCCTGGATCCCAGTACGGCAAGTGGCCTGGAAGTCCGAACTCCCACAGCAATGATGACTTTGAAGCCTGGACGGCTTTCCGACCCCGCACCAGCTCCAATGCCAGCACATTAAGCGGTCGTCTCTCACCGTTTATTGATGACGAACTTGGAGACTCTGATGTTCACATGGTCTACCCAGGCCCTGGGTCAGGGACCAAAATGACCTCCACCCTGCCCAGCCTGTCTGAAATGGCTGGATCTCTAGGCCACAGTGGCTCTGAGAATGTGATGGAGAATCTTCTGGATAACCTCAACTTGCTTTCACCTAAGAACCCATCCACGGGAGGTCCTGGGTCAGGATCCAACCAGTCCTCCCCCTCCTCGCTCATGCAGGCCAGTCCAGGTTACTCCCCCTACAGTTCCCCAGGTCTATCGGCAGTAAGCCAGCAGACCCAACAGGACTTTCGCAAGTGTCTCTACGGCCAGGCAGGAATGGGAAGCATGTCCCCTATGCCCATGCAACCTCTGCCAGAAAGCAAGCCAAGTTTTGGTCCTGGTGGAGGAACTATGGGTCAGTTTAACTGCACAGCAGGACTCCTAAAAGAGTTACTCACATCTGATGGGGAGCCTGGAGACCTCATGCCTTCAGTGGACACTGTTGTGTCCCAATCTGCTGGAGGGAGTGGATGTATGTTGCCTCCATACAGCAGTGGGCGAAACGAACTCATGGGCGGTGGACCTACCCACAGTCACACTCTTTCTCACCCACACAACATGCACGGACAAGCCCCGCCCACATCTGTGGCACTGAACGGGCGATCTCTGCACCCTCTGACTGCCATTGGTCACAGCAGTGTGGGCGGACGCCTGGGAAGTGGTAAATCTCCAATGCAGATGCAGTATGGAGGCTCAGGTCATCTCGGGGGTGGACTTCCTCCATACTGCAGCATGAGCAGTAACGGATACGGCCGCGGCCCAGGGATGATGGCCCACCAGCAGCTGCAACACCTGGAGAAGCTACCGAGCGATCTGGACGGGATGCCAATCGAGCGATTCGAATGTGACGTGGAGTCGATCTTGCATGACACGCTCATGGACGGAGAATCGCTGGACTTCAACTTCGATCCCATGAACTCCCAACAGGGGTTCGTGCCTCACAGTGTAAAGACCACCACTCACAGCTGGGTGTCTGGgtaaAAACCCTCATCACTGAGCAGCACCCAAACCCCCCGTCATCCCTCGCCAGGGAACTAAGCCCCTGTAAATTTGTTCACTTTTCTTCAGCAGAGGCGGCTGAGATTCCACCTCACACTGCCAAGCACACTGGCTCAATGTGGAGCTAAATTGCAAGGACGTCAGACATTGGGACTCGCGTTCAAACCAAGTGCCAAACCAGGTGCCTGTGCTCCAAAGCCAAATTGACAAGCTTTATTTTGCTGCCTTCAGTGGTCAAATCAGGGCAAAAAAAAACCTGAGGCCCTTACATCTGCTGCAACACACATTCATCAACATCCACACCAACTTCTCTAATGATTTTTACAGCCACATTTTCCATTAAGGGCAAACTGTGATAAGGTGTAAACGCCTAATAGCTAATAAACGGTAATAGCTCTCTTTCGTTGTCGTGTTGTCAGTTCAAAAACCCTACCCTGCCATTTTTGTCTAAGGGTAATGCATTCATGCTGCGCTTCATGATTGGCCTTATTGGGAAGAAGAACTGGAAGAGCGGGAATCGCTGTAAATAGATTTATTTAGAAACAGTCCTGCAGAATCATGATATTAGGGAAATCGATGCCGACTAGTTGAACTACGTCGCATACAGCACATCATAACACTTTCATTTCTGTCTCGTCGGCATATTTGAGCGAGCAGAAGTACTACATTTCTAAACCGTATGTTACTATAAATCGGTGTACAGAGAGTTTACACGATGATATCAACAATCAGGGCAACagatttaatgttgttttgtaaATCGGAGAGAAACTGGATTCGacgtttttacatttttggcGGACGTACATGGGAAAAGAGTTGTTTCTCGTCTGAATTGTATACATCTTTCCACGTTTCTTGTAAATACatgaaatatatatttcagaAACATATAAAAGTAgaatattttagtgttttttttttcttttgttatatcACAGTTATTCTTATTGCTGTTTATTAGCGGCTTCAGTTTGAtcgtttgtttgttatttataggaatagttcacccgataatgaaaaaagaaaaacaatttgcTTGTGTCATTCcaaactcatttatttattctgtgaacaaaaaaaaaacgatgactttttgaataataacacagctattctttttttaatatataacgaGGCTACCATTGCTATTCAAACAATTGTCAGTAAAAAgttctgacaatattttttacaaaatgaatGCTTTTATGTGTCATGGAGCAAAGAAACTCAGTTTGGAGCGACattagggtgaataaatgatttcAGAATTTCTCATTTTCTTGTCTAAGCTGTGTATAgcacattttgtaaatttttagGGTCCTTAAAAGACAAATCCAGCATTTTGTACAACTCAAAAGTTTTGTAACCTATGTACaatgttagtttaaaaaaaaaaaaagtcaaatttttcCAAAAACTGTTGGATTTGCTCTTAAAATCCATGTGAATCGGCAGTTGCTGaggcttttatttcagtatgttgatgtactttcaactgaaactgaatattaagtaggggggcggggctttcttttgcacATCATGCTTTAATAGAGAATTAAcataagaggggcgtggttaaggtTATTAATATATTGTTGCTATGGAAGCTCTTAGGTTGACGTCAGCAGAAGGATCGTCACTAGCTCATACTTGGattgaacttttttttcttcagtggattaacttacaCTGATTAACTATTCactttaagaataacaatgtgaactaacaattttgatttcacatggactttaagaatttttttacaaCCATCAAAACGTTTTATAAGTGATTAAAGTAGTTTAGAGATTCAGCGCTTGGAGAATCTTACGCCTTCACCACCACATTGAATCTGTTGCTGTAAAAAAGCTCCGGTTGTCTACTTTTAACAAAGTGTAGAGACTATTCTTGACTTCACATTATTTATTTGGCTAAAGGAGAAGTGATTGTATCAAGTCATGGTGTATTGTATTGTACACCTCTCTCAGATTGCAGGCACTGTGATGTATATGTTTGTGGTGGTCTGTGCTGCCTCAACCTTCATGTTCATTTCTCATTACCAGAAAAACATCGACAGTTTGGACTTTTTGCACTACCAGGTCTTTATAATGGTCAAAATGAGCAAATGAAAGGGTGAAAACAAGAATTGACTTCTTGATTAGTGTTTCAAAGCAAATGTTGAAAACTTTTTAATGCTTTGCATAAATTAACATATGTTAAGTTCTCATTATTggccttttttaattaaaatatcgaGTGCTTGATGTTGTTAGATGTGTTTATTGAGGACGCTAACACAGTTTTCTAACCTGACGGGATGTGATAACAATCCGCAACTAACTCGCATTTTGGTTTCTATTGCTGTGGCTTCATGCTGTTTAGCCACGCCTATTACGAAATCCTATCGGTCTAAAATTCCACTCTGCATACTTTAGATGAAATATGATTGGCTGTGCCATAATTTTCACTTCCAGTGTAAACAGACAAATTTCTCGTGCAACTAAAGCCATCTAGAGTGCTGTTGTTTGAAAACCCCATTCATTTTCTCTACAGGGAAGCAATAGTTGATACATAAAGCCCTGTTCTGTGTCaatgttagagtgtatgggtgtttcccaggactgggttgcagcaAATAAATGTTCTACGgcgtatttgtattattatttctgaATACCCATGGGAAAAATTCTGTAGCCATCATATTTTTTGGCTAGTTTCGGAAAATAAAAACGTAAACTATTATCGTTAACTTtaacgtttatttatttttaaatacaaaaatcacTGTGCCCACCATCATGGACACGCATTTGCTTTGTGAATTTCGCAGGTGAGCCCACCCACGCACATCTCCGAACGCTAATAACTATTGCGATTATCGCCATCGCCCGTTTGTTTGTATTAACGACAAGATGTTTGATATTTCATGTTTTGATAGAGCTGTGGAGTCCTGTTCATGTCCCGAATGTTCGCGCATAGTTCTGAAGAATATGAAGTATATTTAGAGTAGAAGATCATGTACACGCAACGCTTTTTCTCTTTTGTACACCGACACTGTTATTCTTGTGTTATTCTTTCAGTTTGTACTGgacaaaagaaaagtaaaaaaaaaaaaaaactgaaagaaatttAGTAGACAATTTAGCCGTTTTCTCTTCAGATTGCGGAGTTTGGAccaatttttaatgaaaataaataaataaatcaatatataaattaaaatactgCACTTTTTATCTGGAGATGTAATGAGTTCTCCTTCTAGAGaggttgaaaataaaatgaagatgATCTATTTTGAAACAAACTGTTACATTTCTTAACTTATGTACAGGAATGATTTGATTCGTGATTGAAAGATGACTTGAGGTGCAATTTGTGTAGAGAAAGTAATCTATGAGAGAGAAATGCTATCTGTTAAGCTGACATATGCCAATACTGACAcatgtgtattatatattatCTCTTGGTTTTTCGAGTTGGTTAGCAGTGAGCTGAAACCGTTTGTGAAATGTGAGcgctctgatgtttttttttttgctcttgatGCCGATGTTGTGCTTGTATTCCTGTACAAGAAACATGCTgccgctgtaaaaaaaaaaaaaaaaaaaagccatgtgTATATAAATTATGTTATATAAAGAAGAATACAATG
>TCONS_00016633
ATGGCTGACGCAGCCCAAAACCAGATGGTGGAGATCGACCCGGACTTCGAGCCGCTGTCCCGGCCCCGCTCCTGCACTTGGCCGCTGCCGCGACCCGAGTTCCCAAACCCCGCCGCCGCGGACTCCAACACTTCATCCCCGGCTCCGTCCGTCAAACAGGAGCCTTCCAGCACCGCGGACTTCATCAACAACCTCAGTCTGCTAGAGGAGAATGAGGACTACCCGGACCAGAAGCCTCTCATGCTCTGCAGCGAGTTCCAGTGCCAGGAGAACTGCATCCACCAGCAGCAGATCCCGAGTCAGCAGCAACAGGTGCCCGTGCTGTCCTCTCCGGTGGCCGCCGCCGCCGCAGCCGCAGCAGCCGCGCAACGCAAAAGCAGCTCGTCTCGGCGCAACGCCTGGGGAAATATGTCGTACGCGGACCTGATCACCAAAGCCATCGAGAGCTCCCCAGAAAAGCGGCTCACCTTGTCTCAGATATACGACTGGATGGTGAAAAGCGTCCCGTATTTTAAAGACAAGGGGGATAGTAACAGCTCCGCGGGCTGGAAGAACTCAATCAGACACAACCTGTCCCTACATAGTAGGTTCATCCGAGTGCAGAATGAGGGGACTGGTAAGAGCTCTTGGTGGATGCTCAACCCTGAGGGTGGGAAAAGTGGAAAGTCTCCTCGACGCCGGGCGGCCTCCATGGACAACAACAGCAAGTTTGCCAAGAGCAGAGGACGAGCGGCAAAGAAAAAGCTGGCTCTTCAGGGTGGCCCCGAGGGTGGCGCGGACAGCCCTGGATCCCAGTACGGCAAGTGGCCTGGAAGTCCGAACTCCCACAGCAATGATGACTTTGAAGCCTGGACGGCTTTCCGACCCCGCACCAGCTCCAATGCCAGCACATTAAGCGGTCGTCTCTCACCGTTTATTGATGACGAACTTGGAGACTCTGATGTTCACATGGTCTACCCAGGCCCTGGGTCAGGGACCAAAATGACCTCCACCCTGCCCAGCCTGTCTGAAATGGCTGGATCTCTAGGCCACAGTGGCTCTGAGAATGTGATGGAGAATCTTCTGGATAACCTCAACTTGCTTTCACCTAAGAACCCATCCACGGGAGGTCCTGGGTCAGGATCCAACCAGTCCTCCCCCTCCTCGCTCATGCAGGCCAGTCCAGGTTACTCCCCCTACAGTTCCCCAGGTCTATCGGCAGTAAGCCAGCAGACCCAACAGGACTTTCGCAAGTGTCTCTACGGCCAGGCAGGAATGGGAAGCATGTCCCCTATGCCCATGCAACCTCTGCCAGAAAGCAAGCCAAGTTTTGGTCCTGGTGGAGGAACTATGGGTCAGTTTAACTGCACAGCAGGACTCCTAAAAGAGTTACTCACATCTGATGGGGAGCCTGGAGACCTCATGCCTTCAGTGGACACTGTTGTGTCCCAATCTGCTGGAGGGAGTGGATGTATGTTGCCTCCATACAGCAGTGGGCGAAACGAACTCATGGGCGGTGGACCTACCCACAGTCACACTCTTTCTCACCCACACAACATGCACGGACAAGCCCCGCCCACATCTGTGGCACTGAACGGGCGATCTCTGCACCCTCTGACTGCCATTGGTCACAGCAGTGTGGGCGGACGCCTGGGAAGTGGTAAATCTCCAATGCAGATGCAGTATGGAGGCTCAGGTCATCTCGGGGGTGGACTTCCTCCATACTGCAGCATGAGCAGTAACGGATACGGCCGCGGCCCAGGGATGATGGCCCACCAGCAGCTGCAACACCTGGAGAAGCTACCGAGCGATCTGGACGGGATGCCAATCGAGCGATTCGAATGTGACGTGGAGTCGATCTTGCATGACACGCTCATGGACGGAGAATCGCTGGACTTCAACTTCGATCCCATGAACTCCCAACAGGGGTTCGTGCCTCACAGTGTAAAGACCACCACTCACAGCTGGGTGTCTGGGTAG

Function

symbol description
foxo1a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on gluconeogenesis. Acts upstream of or within several processes, including lymph vessel development; smooth muscle cell proliferation; and smooth muscle tissue development. Predicted to be active in nucleus. Is expressed in digestive system; head mesenchyme; pericardial region; and pharyngeal arch. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human FOXO1 (forkhead box O1).

GO:

id name namespace
GO:0048745 smooth muscle tissue development biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006094 gluconeogenesis biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0042593 glucose homeostasis biological_process
GO:0048659 smooth muscle cell proliferation biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0001945 lymph vessel development biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0008134 transcription factor binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-061013-59 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on gluconeogenesis. Acts upstream of or within several processes, including lymph vessel development; smooth muscle cell proliferation; and smooth muscle tissue development. Predicted to be active in nucleus. Is expressed in digestive system; head mesenchyme; pericardial region; and pharyngeal arch. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human FOXO1 (forkhead box O1).

Ensembl:

ensembl_id ENSDARG00000099555

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00016631 False 1146 mRNA 0.54 2 3284416 3368645
TCONS_00016632 False 5915 mRNA 0.43 4 3284416 3379041
TCONS_00016633 True 1959 mRNA 0.58 3 3284684 3372979

Neighbor

gene id symbol gene type direction distance location
XLOC_008256 LO017656.2 coding upstream 33195 3246475 ~ 3251221 (+)
XLOC_008255 NA coding upstream 44459 3237595 ~ 3239957 (+)
XLOC_008254 NA coding upstream 60968 3219134 ~ 3223448 (+)
XLOC_008253 CABZ01053592.1 coding upstream 83119 3169974 ~ 3201297 (+)
XLOC_008252 rcbtb2 coding upstream 121830 3125136 ~ 3162586 (+)
XLOC_008258 NA coding downstream 3773 3382814 ~ 3383114 (+)
XLOC_008259 FO704837.1 coding downstream 127268 3506309 ~ 3506423 (+)
XLOC_008260 NA coding downstream 148364 3527405 ~ 3529781 (+)
XLOC_008261 LHFPL6 coding downstream 160003 3539044 ~ 3652151 (+)
XLOC_008262 NA coding downstream 214298 3593339 ~ 3595259 (+)
XLOC_008463 BX663520.1 misc downstream 17873150 21252191 ~ 21252282 (+)
XLOC_008251 NA non-coding upstream 294465 2988791 ~ 2989951 (+)
XLOC_008250 NA non-coding upstream 418487 2865624 ~ 2865929 (+)
XLOC_008248 NA non-coding upstream 428787 2844812 ~ 2855629 (+)
XLOC_008264 NA non-coding downstream 303271 3682312 ~ 3718383 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00016058 NA coding CM030122.1 CM030122.1 4376445 ~ 4378160 (-)