XLOC_008307 (foxl2a)


Basic Information

Item Value
gene id XLOC_008307
gene name foxl2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 7054754 ~ 7058214 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00016685
AAACGATGGATGTTGTTCACACCTGAAAGAGCATTTAAATTCCACTCTTTGACTCGTGGTGGGGGCTTAACAAACCTGGTTTGCGTGCGCAATGATGGCCACCTACCCAGGCCACGAGGATAACGGCATGATACTCATGGACACAACCTCGAGTTCAGCGGAGAAAGACCGAACAAAAGACGAAGCTCCTCCAGAGAAGGGACCGGACAAATCCGACCCGACCCAGAAACCACCGTACTCATACGTGGCGTTAATCGCGATGGCAATCCGCGAGAGCTCGGAGAAGCGTCTTACGCTGTCCGGTATATACCAGTACATCATCAGTAAGTTTCCATTCTACGAGAAGAACAAGAAGGGATGGCAGAACAGCATCCGACACAACCTGTCACTCAACGAGTGCTTC
>TCONS_00016686
AAAACCTTTAACGCTGATATTAAGCTCCACAAATAGGTCTAACCTACAAAAAACACTGGGAAGGTTTGCGTGCGCAATGATGGCCACCTACCCAGGCCACGAGGATAACGGCATGATACTCATGGACACAACCTCGAGTTCAGCGGAGAAAGACCGAACAAAAGACGAAGCTCCTCCAGAGAAGGGACCGGACAAATCCGACCCGACCCAGAAACCACCGTACTCATACGTGGCGTTAATCGCGATGGCAATCCGCGAGAGCTCGGAGAAGCGTCTTACGCTGTCCGGTATATACCAGTACATCATCAGTAAGTTTCCATTCTACGAGAAGAACAAGAAGGGATGGCAGAACAGCATCCGACACAACCTGTCACTCAACGAGTGCTTCATCAAGGTGCCTCGGGAGGGCGGCGGTGAGCGAAAGGGCAACTACTGGACCCTGGATCCTGCATGCGAGGATATGTTTGAAAAGGGCAACTACCGGCGAAGACGACGAATGAAAAGACCGTTCAGGCCTCCACCGACCCATTTCCAGCCAGGCAAATCTCTCTTTGGCGGTGAAGGGTACGGTTACCTCTCCCCGCCCAAATACCTACAGTCTGGTTTTATCAATAACTCATGGTCTCCTGCACCCATGTCATATACCTCCTGTCAGGTGAGCAGTGGGAGTGTGAGTCCCGTTAATATGAAAGGCTTATCCGCACCATCGTCGTACAATCCATACTCGCGCGTGCAAAGTATAGGTCTTCCCAGCATGGTAAACTCTTACAACGGCATAagccatcatcatcaccaccaccacaCGCATCCTCATGCGCTCCCGCACGCCCAGCAACTCAGTCCCGCCACGGCTGCAGCACCTCCGGTGACCACTGGTAACGGAACAGGACTGCAGTTCGCTTGCTCGCGCCAGCCTGCAGAACTTTCAATGATGCACTGCTCATATTGGGATCACGAGAGCAAACACTCTGCACTACACGCGCGGATTGATATATAGTTCGGGCATCTCGAGATCAATGACACATCAACATATTCACTGaaagacagtaaaaaaaaa

Function

symbol description
foxl2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within maintenance of animal organ identity. Predicted to be located in nucleus. Is expressed in female organism; gonad; ovarian follicle; ovary; and testis. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and primary ovarian insufficiency 3. Orthologous to human FOXL2 (forkhead box L2).

GO:

id name namespace
GO:0048496 maintenance of animal organ identity biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030154 cell differentiation biological_process
GO:0009653 anatomical structure morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060512-241 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within maintenance of animal organ identity. Predicted to be located in nucleus. Is expressed in female organism; gonad; ovarian follicle; ovary; and testis. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and primary ovarian insufficiency 3. Orthologous to human FOXL2 (forkhead box L2).

Ensembl:

ensembl_id ENSDARG00000042180

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00016685 False 403 mRNA 0.51 2 7054754 7057545
TCONS_00016686 True 1057 mRNA 0.51 2 7057050 7058214

Neighbor

gene id symbol gene type direction distance location
XLOC_008306 NA coding upstream 179206 6867276 ~ 6875548 (+)
XLOC_008305 sirt2 coding upstream 246791 6786757 ~ 6807963 (+)
XLOC_008304 NA coding upstream 268699 6785649 ~ 6786055 (+)
XLOC_008303 si:ch1073-228b5.2 coding upstream 269789 6773876 ~ 6784965 (+)
XLOC_008302 CU694757.1 coding upstream 282634 6770586 ~ 6772120 (+)
XLOC_008308 pik3cb coding downstream 6605 7064819 ~ 7161877 (+)
XLOC_008309 her8.2 coding downstream 117968 7176182 ~ 7178865 (+)
XLOC_008310 her13 coding downstream 129014 7187228 ~ 7190183 (+)
XLOC_008311 NA coding downstream 676275 7734489 ~ 7737531 (+)
XLOC_008312 CR589941.1 coding downstream 747565 7805779 ~ 7805920 (+)
XLOC_008463 BX663520.1 misc downstream 14193977 21252191 ~ 21252282 (+)
XLOC_008301 CU633984.1 non-coding upstream 327672 6678521 ~ 6727082 (+)
XLOC_008299 CU655863.1 non-coding upstream 495569 6559050 ~ 6559185 (+)
XLOC_008317 CR293508.2 non-coding downstream 1624608 8682822 ~ 8682937 (+)
XLOC_008318 CR293508.3 non-coding downstream 1673538 8731752 ~ 8731866 (+)
XLOC_008319 NA non-coding downstream 1704260 8762474 ~ 8765029 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000363_00413629_00414546 FOXL2 coding CI01000363 null 412894 ~ 415022 (-)