XLOC_008320 (ap2s1)


Basic Information

Item Value
gene id XLOC_008320
gene name ap2s1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 8767650 ~ 8799977 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00016702
cacaCCTTGCAGCAACGGCCCTCAGCTCGCATCCTGTCCGGAGAAGATAGCGGGCGGCTACAGATCTTAACCAAGGCAGAGGCGTCTGTATTTcctaattaaatcaattaaacatTCACCAGAATAAGTCCGACAACCGCGAACGACAAAAACTGAGCACAATGATCCGCTTTATCCTCATCCAGAATCGGGCTGGGAAGACCAGACTGGCCAAGTGGTACATGCAGTTTGATGACGATGAGAAGCAGAAGCTAATTGAAGAGGTGCATGCTGTAGTGACAGTCCGTGATGCCAAACACACCAACTTTGTTGAGTTCAGAAACTTCAAGATCATTTACAGGCGGTATGCTGGCCTGTACTTCTGCATCTGTGTGGATGTGACGGACAATAACCTGGCATACCTGGAAGCTATTCACAACTTCGTTGAGGTTCTCAATGAGTATTTCCACAATGTGTGCGAGTTAGATCTGGTCTTCAATTTCTACAAGGTGTATACGGTGGTGGACGAGATGTTTCTAGCAGGAGAGATCAGAGAAACCAGCCAGACGAAGGTGCTCAAGCAGCTCCTCATGCTGCAGTCCCTGGAGTAAACTGtcaatcagtcaaccaaccaatcaaacaacCACCATTGTGTCAGGCTCCGCCCACCCCGCTGCAGCCAAGCCATATGatttgtgtgtatgagtgttgtCATGCTGAAAATCATCCTCTAACATTTCACCTTTTTCTTTACACTCGCATCCACCTCACAGGATGTTGCCGTTCTGTCCTGCAACTTCATGAATTTTCGAGGCAGATAAGAATTCGTAAAACTTCCTCGGTTATGTGACCTGATTATATCTTGGCATAGCCAGAATTGAATTCTTCAGCGATTTTATAGCACACTAGACTTCAGTGTTTCCGACTGGAAGCCTCTCCAAGCCTGTTCATTAACACTAACATAGATAATAGCGTCATGTGGGCCAAAAAACTGCCATGGCACGAAAGTGACAGTCATAATTGCAAGATTCCGGGGCTGCACTGCAATATCGCAATGAGAAAAACTTGATTTGATGTCCATTTAAGGAAATTCCCATATATGTactattaaaaaaagaatcaaatgTTTAATATGCTGCACTGCAAATAATAAATTTGTTACtgctttgtcttgttttctgGTACAAGTATCCATATTGTTAAAACTCCAAATACGTAAAGGTGATCTTCCTGTTGGTGactatatctttttttatacaaTTAAGATGTTCATAATGGTGTCACAAAAAGGGTTTCGCAACAACTGTTGGCActtttgagagtaaaaaaaaaacatacaggcaaAACCAAATTAACTGACCGTTTCAGTATGGAGATGTCATTAATCCATGAACAGTTCCTGCTTGTCTTAACTATTTCTGAATTGTAAGAGGCGATTCGGTtgtaactaatgttaacatgGCTGCTAAAAAAAGTGTCAATATGGACCTTTCTGGATTCTAATAAGATTTGGAAATGAAGATATAAAACAGCAAATACATAAATaccattgttattatttacatccctcaaaatggtctaccCACTACTGATTCGGTGAGGTCCTAAGAAGTGAAATTAAAATTTATGTcaaacaaaatacattattttagatCCACAGCTTTGGCCAATTGTATTCTTTTTGTtttgcctattattattattttttttttttcactctaaAAAGTAATAATCGGGTTAATCAGCCTAATGGtgaatttaaagaaaaatgaaggagaaaacaaaatatttcctTGCCATACTCTTACTATGCatctgtttcttctgttgaacacaaaggaaggtaTACTGAAGTATGTTGGGAAAAaacatccattgacttccatagtcgaAACTAAAATATGTAAATCAATAGTTGTTTTTctcccccaacattcttcaaaatatcatcctttgtATTCAACAGTAACTTAAACGGGAACAAGTGGATGGTTAAAAGTGTTGTGAGGGTTAAAATTCCAAAATGTTACAacaaagtcaaataaaaatataaatttacagcAAGATTTTACTATAAAATCAAACatataaatgtttgtatttacgACAGACTCCCGTTGCTCGCATCAAAAGGATGGGGCGAATatgattaatgtatttttttcaacgACGacgtttatttttttggttaactATTACTTAAAATTTCCTTCTCAATGTATGTTTTGGTGTTAGTAtctggaaaacaagacaaaaacacagcAAGCCTGTTCGCAGTGTTAAGTCAAAGTCTGTGAAGGTTGTTTTGTATTGtgtacatatacattatatatgcATCTATTTGAAACGTAATTGTATGAACTAACTAGTCATTCCAAGCCTCTAAACCGGGTCAGTTTCTGCTCGTTGTAAGTCTTCTGGCTTTGTGGAGAACTGAAGCCGGCGATTAGCGAGCGCTTTAGAGAACCAGGCTGAGTGGAAGAATGAAGCTCGAGGGAAATGACAAAAGATGGTCTACTTTTAATTTCCCCTTTTGTGGCGCTGCTTCCCTCGCGCCAAAAGGCTCTATGGCAACAGCTCAGCCTTGAAAATTCCATTACACTTCGGGTCATACGTTACGATgagtttttgtctttattttgtacTTGTATGTTTTATATGGTCTTTCTTTTCGTCCCTTCAGCCTTAGTTTGAAATTTGGTAGGTCTACCTATTTGTCCCTGTGAAATTGCAGATTAAACGCTGATTTAAGTGGTGTTTCTCTTGCGTATGTTTCTGTCAGTGTATATATAACCATGAAGGTGAAATAAAACGTACAACTTCAAA

Function

symbol description
ap2s1 Predicted to enable clathrin adaptor activity. Acts upstream of or within habituation. Predicted to be located in membrane. Predicted to be part of AP-2 adaptor complex. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in familial hypocalciuric hypercalcemia 3. Orthologous to human AP2S1 (adaptor related protein complex 2 subunit sigma 1).

GO:

id name namespace
GO:0006886 intracellular protein transport biological_process
GO:0016192 vesicle-mediated transport biological_process
GO:0015031 protein transport biological_process
GO:0046959 habituation biological_process
GO:0072583 clathrin-dependent endocytosis biological_process
GO:0030117 membrane coat cellular_component
GO:0030122 AP-2 adaptor complex cellular_component
GO:0016020 membrane cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0035615 clathrin adaptor activity molecular_function

KEGG:

id description
ko04144 Endocytosis
ko04961 Endocrine and other factor-regulated calcium reabsorption
ko04721 Synaptic vesicle cycle
ko05016 Huntington disease
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-040426-2174 Predicted to enable clathrin adaptor activity. Acts upstream of or within habituation. Predicted to be located in membrane. Predicted to be part of AP-2 adaptor complex. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in familial hypocalciuric hypercalcemia 3. Orthologous to human AP2S1 (adaptor related protein complex 2 subunit sigma 1).

Ensembl:

ensembl_id ENSDARG00000026967

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00016702 True 2805 mRNA 0.38 5 8767650 8799977

Neighbor

gene id symbol gene type direction distance location
XLOC_008319 NA coding upstream 2621 8762474 ~ 8765029 (+)
XLOC_008318 CR293508.3 coding upstream 35784 8731752 ~ 8731866 (+)
XLOC_008317 CR293508.2 coding upstream 84713 8682822 ~ 8682937 (+)
XLOC_008316 tmem160 coding upstream 367559 8394819 ~ 8400091 (+)
XLOC_008315 egln2 coding upstream 384653 8335600 ~ 8382997 (+)
XLOC_008321 CR925772.1 coding downstream 239073 9039050 ~ 9039164 (+)
XLOC_008322 ppm1na coding downstream 253082 9053059 ~ 9069172 (+)
XLOC_008323 si:dkey-202g17.3 coding downstream 272844 9072821 ~ 9089507 (+)
XLOC_008324 ptgir coding downstream 317353 9117330 ~ 9184449 (+)
XLOC_008325 CU467862.1 coding downstream 405287 9205264 ~ 9211131 (+)
XLOC_008463 BX663520.1 misc downstream 12452214 21252191 ~ 21252282 (+)
XLOC_008312 CR589941.1 non-coding upstream 961730 7805779 ~ 7805920 (+)
XLOC_008311 NA non-coding upstream 1030119 7734489 ~ 7737531 (+)
XLOC_008329 FP016239.1 non-coding downstream 614176 9414153 ~ 9418151 (+)
XLOC_008330 CR936974.1 non-coding downstream 652001 9451978 ~ 9457382 (+)
XLOC_008331 NA non-coding downstream 840710 9640687 ~ 9649456 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G361637 NA non-coding CI01000154 null 981793 ~ 991232 (+)