XLOC_008935 (cldne)


Basic Information

Item Value
gene id XLOC_008935
gene name cldne
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 2638884 ~ 2640966 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00017649
CTGCAAACACAGCCGAGGAATCCGGTCAATCTTGAAAATTCACCTCCAACCCAGTTTCATCAGCCTGGAACTCCTCCCATTCTGGACACAATCTTAAAACTCTGTAAGCCTGTGCAGTGAAGTCACTACAACCCTTCGGAGCGGACAGAAAACACACGTTCAACTTCACAAGcccacaaacaaacaagcaaacatggTGTCTATGTGCCGAGAGATCCTGGGCATGTGCCTGGCCATCATTGGCTTCTTGGGAGCCATTATTATTTGTGCTTTGCCCATGTGGAAGGTGACCGCGTTCATCGGAGCCAACATCGTGACGGCGCAGACCATCTGGGAGGGTTTGTGGATGAACTGTGTGATGCAGAGCACGGGACAGATGCAGTGTAAGATCTACGACTCGCTCCTGGCCTTGCCTCAGGACCTGCAGGCCGCTCGAGCTCTCGTGGTCATCGCCATCATCGTCAGCTTTTTCGCGCTCATCCTGGGCATCGCCGGCGGGAAATGCACCAACTTCGTGGAAAGGGAAGACGCCAAGGCTAAAGTGTCCATCGCCAGCGGCGTGATCTTCATCATTGCTGGAGTTCTGGTGCTGGTGCCTGTTTGCTGGTCCGCCAACACCATCATCAGAGATTTCTACAATCCTCTGCTCACTGATGCTCAGCGGAGGGAGATGGGGGCTTCGCTGTACATCGGATGGGGCGTCGCAGCGCTGCTGATCATCGGAGGTGGAATCCTGTGCAGCTCCTGCCCTCCAAAAGATGAAAAATACAACATGAAATACTCCCAGCCGCGCTCCACCGCCACCAGCAGAGCCTACGTCTGAGAGCTACGCGGAGATCGCAAAGACTTTTGGAgactctctctcactctttcgTTCTAAGACTTGCCAAGAAGATCAATTGAAAGACTGTGTCTGATATTGCATATATAGTGGTTATATAGTGAGGATGTATATATGTGCTGTGATTATACACACTTTTGAGCTGAATGAACACAACTCCTGAGATTTCTGTTGGCACAACTTAACTGTTTCATGTCAAATTCACTTAACGGCTaataacttaatcgatttgtgttgtgcCGACGTGAATGAACTGCGTGGAAGCCTGCATTTGTTTTACAGCGTGCACTCAAGAAAATGATGTTTGCagatgttttggaaaataatGCTTgccgtttgttcaaactactcatttgaaatgagctgaaacaacacaattcttgagtttctttgggacaacctaattgttttatgctcaattcaattaaaattgttaaaaaataataagcttACTTAATTTATTGATGTTCCACCATGAAAAATTGACTAAATAaatttgattgttggtggttcattccactgtggcgaccctggattgataaaattattttaaaaaataattagctaACGTAATTCATTGATGTTCCACCAACAAAATTTTGGCTAAATAAACTTatttgttggcggttcattccactgtggtgaccctggattaataaagttataaaaaatttaaaaaatagctaacttaattccttggTGTTCCACCATCAAAAATTGACTAAATAAACTTAATACTCGGTGGTTGATTCCATTGTGGcgaataaaattataaaaaacatattaagCTATTTTAATTCCTTGATGTTTTCCCaacataatttgattaagttaacttagttgagtgaattcaacataaaacaattaagttttccctcCAAAAAACtcaagctaattttaaataagtagtttgaagaagGCATTTATTGAGTGCAGATCCCTGAAAGagaaaaatgtgcatttataatgtgattttattcaatattttttgttgatttttagtttttttttaacaatgcattCTTATATTATACGTTTAATATGACGAGAGGAATAGTTTCTTTAAATGTAAGACGTAAGCTTTAATACTGTAAAGATTAAATGTGCATTAACTTagcttttgtgtttgtttgtcagtgtataaattaactttttttttttgcataaagatGTCTTAATCAGTAAAATTGTCctgatatttgtttttgtttattataataaatggTTCTGTAAAACTGTAAA

Function

symbol description
cldne Predicted to enable structural molecule activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be located in cell junction and membrane. Predicted to be integral component of membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; blastomere; digestive system; ectoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Orthologous to several human genes including CLDN4 (claudin 4).

GO:

id name namespace
GO:0070830 bicellular tight junction assembly biological_process
GO:0055113 epiboly involved in gastrulation with mouth forming second biological_process
GO:0007155 cell adhesion biological_process
GO:0005886 plasma membrane cellular_component
GO:0005923 bicellular tight junction cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005198 structural molecule activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-010328-5 Predicted to enable structural molecule activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second. Predicted to be located in cell junction and membrane. Predicted to be integral component of membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; blastomere; digestive system; ectoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Orthologous to several human genes including CLDN4 (claudin 4).

Ensembl:

ensembl_id ENSDARG00000043128

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00017649 True 2083 mRNA 0.40 1 2638884 2640966

Neighbor

gene id symbol gene type direction distance location
XLOC_008934 cldnj coding downstream 5993 2631421 ~ 2632891 (-)
XLOC_008933 NA coding downstream 12956 2618279 ~ 2625928 (-)
XLOC_008932 NA coding downstream 27714 2598804 ~ 2611170 (-)
XLOC_008931 dnajc30b coding downstream 42759 2589949 ~ 2596125 (-)
XLOC_008930 srprb coding downstream 119244 2510761 ~ 2519640 (-)
XLOC_008936 cldnf coding upstream 9821 2650787 ~ 2652640 (-)
XLOC_008937 cldna coding upstream 14600 2655566 ~ 2657508 (-)
XLOC_008938 si:ch211-235m3.5 coding upstream 59680 2700646 ~ 2726662 (-)
XLOC_008939 ppp5c coding upstream 86704 2727670 ~ 2754056 (-)
XLOC_008940 CABZ01086049.1 coding upstream 95417 2736383 ~ 2736498 (-)
XLOC_008928 NA non-coding downstream 310600 2323666 ~ 2328284 (-)
XLOC_008927 AL954387.2 non-coding downstream 372801 2265969 ~ 2266083 (-)
XLOC_008910 LO017713.1 non-coding downstream 1316978 1321790 ~ 1321906 (-)
XLOC_008942 NA non-coding upstream 172550 2813516 ~ 2816142 (-)
XLOC_008946 CABZ01086029.1 non-coding upstream 277291 2918257 ~ 2931021 (-)
XLOC_008951 NA non-coding upstream 474371 3115337 ~ 3116262 (-)
XLOC_008952 NA non-coding upstream 519472 3160438 ~ 3162459 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
rainbow trout (Oncorhynchus mykiss) G2180066 LOC106563774 non-coding NC_048593.1 CM023247.2 36358160 ~ 36359289 (-)
mexican tetra (Astyanax mexicanus) G119618 NA unknown NC_035910.1 CM008313.1 5822510 ~ 5831030 (-)