XLOC_009245 (pafah1b1a)


Basic Information

Item Value
gene id XLOC_009245
gene name pafah1b1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 25273185 ~ 25319663 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00018171
CGCCTGCAGAAGTCAGCCGATGCGCGCCCCCGTGCCGTGTAGAGGCGAATGCGGCGCTGCAAGGAGGCAGACCCCGAGACTTCAGCCCCCCTTTTCAACACGAAAATAACACTTTTGTCGTCCATTATCAGCTTCTTCTGAGGAATAACTTTCAGCGCTGACTCTGTATGATGCAGAGACCGTCTGGTTGGTAAATGCCTGCAGGCTGTCAATGTGTGGTGTACCTGGAGACTGTCTTTAAGGAGAAGTGTTTGGGGTGAGCTGCTGACCACCCTGCGAGCCGGACCCGGCGTCCTATCTCTGATCTCCTGCCAAGGAGACAGCAGTTGCTGCACACTCTACACCTGACCCCCATCCCCACCCCGTCCTGTCCCGTCCCTTCTGCCAACATGGTGCTGTCACAGAGGCAACGTGACGAGCTAAACCGAGCGATAGCTGATTACCTTCGTTCCAATGGATATGAAGAGGCATATTCAGTTTTCAAAAAGGAGGCGGAATTAGACATGAATGAAGAATTGGACAAGAAATATGCAGGTCTCTTGGAAAAGAAATGGACTTCAGTCATCAGATTACAGAAAAAGGTGATGGAGTTAGAATCAAAACTGAATGAAGCAAAAGAGGAGATTAATATAGGTGGGCCAATTGGACAGAAGCGAGACCCCAAAGAATGGATCCCCCGTCCTCCTGAGAAATACGCTCTGAGCGGCCATAGGAGTCCTGTCACCAGAGTCATTTTCCATCCTGTTTTCAGCGTCATAGTTTCTGCCTCAGAGGACGCAACAATAAAGGTATGGGATCATGAAACTGGAGATTTTGAAAGGACCCTCAAAGGCCACACAGACTCCGTGCAAGACATTTCCTTTGACCACACTGGAAAGCTGCTAGCCTCGTGTTCAGCGGATATGACCATCAAGCTCTGGGACTTCCAGGGCTTTGAGTGTATCAGGACCATGCACGgacACGACCATAATGTTTCATCTGTAGCTATTATGCCCAATGGAGATCACATAGTTTCTGCCTCAAGGGATAAAACCATTAAAATGTGGGAGGTTGCCACTGGATACTGTGTTAAGACATTCACCGGACACAGAGAGTGGGTCCGCATGGTGCGGCCCAACCAGGACGGGACCCTGATTGCCAGTAGTTCTAATGACCAGACGGTGCGTGTTTGGGTGGTGGCCACAAAAGAATGTAAAGCAGAGCTGCGCGAGCATGAGCATGTGGTGGAGTGCATTTCTTGGGCCCCTGAAAGTGCCCATCCCACCATCCTGGAGGCCACCGGCTCAGAGACCAAGAAGAGTGGGAAACCTGGTCCTTTCCTTTTGTCTGGTTCCAGAGATAAGACTATCAAGATGTGGGATGTGAGCATTGGCATGTGCCTTATGACACTGGTTGGCCATGATAACTGGGTGCGTGGGGTTCTTGTGCACCCTGGAGGAAAGTACATTGTGAGCTGTGCTGATGACAAGACTTTGAGGATCTGGGACTACAAAAACAAGCGCTGCACGAAGACCTTGAGTGCCCACGAACATTTTGTTACCTCTCTGGATTTCCACAAGACTGCTCCGTACGTCGTCACCGGGAGCGTAGATCAAACAGTAAAAGTGTGGGAATGTCGCTGATCATACCCGCCAGGACCCTTCACAACACCTCCATGCTCCCCTCCACCCCCACGGACCCATTCCACTTTCCCCTCAGCTTCCTCCTGCTCTTCTGGATGCACTCGAACACCACAGTCATCACCCACGAGCTCCGGTTTAATAACGTGTCCTTTTATGTAAATTATTCTGGATGTAGATCGAgctattaaatgaaaaaaaaaaagtattcttgCATGGTGAATCCAAAACTGTATACTGTAAATTTACATAATGTTGTCTAGAAGTACCATAGGTTTAACACAGGCTGATCTTTCACTCAGCCTGACCTACCGAAGGCAGAAGCTGACTGGGTTAAATGTAGGGCACTAAACTGATAATTTAATGACAGTGTCTGATTTAtatttgtctatttttattttatttagtttattttgttttgttttccactGTCTTAGTCTGTTTGTGCCTAGCTTGGAGACCTTTCAAAGGGGCAAAGGCTACAGAAGGAATCTATAAATGCTGAGGTGGAGAGTTGATCTGGAGCTTGTTATCGGAGTTATTCTGTAGCTTTGTTACATCACTTCTGGAGTGTACTTATACCATTCTCTTCTCTTGTGGATTTAGATAACATTTAATGGTTGCATCTAAGAA
>TCONS_00018172
ATCTCTGATCTCCTGCCAAGGAGACAGCAGTTGCTGCACACTCTACACCTGACCCCCATCCCCACCCCGTCCTGTCCCGTCCCTTCTGCCAACATGGTGCTGTCACAGAGGCAACGTGACGAGCTAAACCGAGCGATAGCTGATTACCTTCGTTCCAATGGATATGAAGAGGCATATTCAGTTTTCAAAAAGGAGGCGGAATTAGACATGAATGAAGAATTGGACAAGAAATATGCAGGTCTCTTGGAAAAGAAATGGACTTCAGTCATCAGATTACAGAAAAAGGTGATGGAGTTAGAATCAAAACTGAATGAAGCAAAAGAGGAGATTAATATAGGTGGGCCAATTGGACAGAAGCGAGACCCCAAAGAATGGATCCCCCGTCCTCCTGAGAAATACGCTCTGAGCGGCCATAGGAGTCCTGTCACCAGAGTCATTTTCCATCCTGTTTTCAGCGTCATAGTTTCTGCCTCAGAGGACGCAACAATAAAGGTATGGGATCATGAAACTGGAGATTTTGAAAGGACCCTCAAAGGCCACACAGACTCCGTGCAAGACATTTCCTTTGACCACACTGGAAAGCTGCTAGCCTCGTGTTCAGCGGATATGACCATCAAGCTCTGGGACTTCCAGGGCTTTGAGTGTATCAGGACCATGCACGgacACGACCATAATGTTTCATCTGTAGCTATTATGCCCAATGGAGATCACATAGTTTCTGCCTCAAGGGATAAAACCATTAAAATGTGGGAGGTTGCCACTGGATACTGTGTTAAGACATTCACCGGACACAGAGAGTGGGTCCGCATGGTGCGGCCCAACCAGGACGGGACCCTGATTGCCAGTAGTTCTAATGACCAGACGGTGCGTGTTTGGGTGGTGGCCACAAAAGAATGTAAAGCAGAGCTGCGCGAGCATGAGCATGTGGTGGAGTGCATTTCTTGGGCCCCTGAAAGTGCCCATCCCACCATCCTGGAGGCCACCGGCTCAGAGACCAAGAAGAGTGGGAAACCTGGTCCTTTCCTTTTGTCTGGTTCCAGAGATAAGACTATCAAGATGTGGGATGTGAGCATTGGCATGTGCCTTATGACACTGGTTGGCCATGATAACTGGGTGCGTGGGGTTCTTGTGCACCCTGGAGGAAAGTACATTGTGAGCTGTGCTGATGACAAGACTTTGAGGATCTGGGACTACAAAAACAAGCGCTGCACGAAGACCTTGAGTGCCCACGAACATTTTGTTACCTCTCTGGATTTCCACAAGACTGCTCCGTACGTCGTCACCGGGAGCGTAGATCAAACAGTAAAAGTGTGGGAATGTCGCTGATCATACCCGCCAGGACCCTTCACAACACCTCCATGCTCCCCTCCACCCCCACGGACCCATTCCACTTTCCCCTCAGCTTCCTCCTGCTCTTCTGGATGCACTCGAACACCACAGTCATCACCCACGAGCTCCGGTTTAATAACGTGTCCTTTTATGTAAATTATTCTGGATGTAGATCGAgctattaaatgaaaaaaaaaaagtattcttgCATGGTGAATCCAAAACTGTATACTGTAAATTTACATAATGTTGTCTAGAAGTACCATAGGTTTAACACAGGCTGATCTTTCACTCAGCCTGACCTACCGAAGGCAGAAGCTGACTGGGTTAAATGTAGGGCAC
>TCONS_00018173
GTGCAATGACTAGTTTTGCCAATTCTGACTTTTACTAGGTGATGGAGTTAGAATCAAAACTGAATGAAGCAAAAGAGGAGATTAATATAGGTGGGCCAATTGGACAGAAGCGAGACCCCAAAGAATGGATCCCCCGTCCTCCTGAGAAATACGCTCTGAGCGGCCATAGGAGTCCTGTCACCAGAGTCATTTTCCATCCTGTTTTCAGCGTCATAGTTTCTGCCTCAGAGGACGCAACAATAAAGGTATGGGATCATGAAACTGGAGATTTTGAAAGGACCCTCAAAGGCCACACAGACTCCGTGCAAGACATTTCCTTTGACCACACTGGAAAGCTGCTAGCCTCGTGTTCAGCGGATATGACCATCAAGCTCTGGGACTTCCAGGGCTTTGAGTGTATCAGGACCATGCACGgacACGACCATAATGTTTCATCTGTAGCTATTATGCCCAATGGAGATCACATAGTTTCTGCCTCAAGGGATAAAACCATTAAAATGTGGGAGGTTGCCACTGGATACTGTGTTAAGACATTCACCGGACACAGAGAGTGGGTCCGCATGGTGCGGCCCAACCAGGACGGGACCCTGATTGCCAGTAGTTCTAATGACCAGACGGTGCGTGTTTGGGTGGTGGCCACAAAAGAATGTAAAGCAGAGCTGCGCGAGCATGAGCATGTGGTGGAGTGCATTTCTTGGGCCCCTGAAAGTGCCCATCCCACCATCCTGGAGGCCACCGGCTCAGAG

Function

symbol description
pafah1b1a Predicted to enable dynein complex binding activity; microtubule plus-end binding activity; and protein heterodimerization activity. Acts upstream of or within brain morphogenesis. Located in cytoplasm. Is expressed in several structures, including gill; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in lissencephaly and lissencephaly 1. Orthologous to human PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1).

GO:

id name namespace
GO:0030154 cell differentiation biological_process
GO:0031023 microtubule organizing center organization biological_process
GO:0007275 multicellular organism development biological_process
GO:0007281 germ cell development biological_process
GO:0000132 establishment of mitotic spindle orientation biological_process
GO:0048854 brain morphogenesis biological_process
GO:0007049 cell cycle biological_process
GO:0051012 microtubule sliding biological_process
GO:0047496 vesicle transport along microtubule biological_process
GO:2000574 regulation of microtubule motor activity biological_process
GO:0051301 cell division biological_process
GO:0007097 nuclear migration biological_process
GO:0007399 nervous system development biological_process
GO:0008090 retrograde axonal transport biological_process
GO:0000776 kinetochore cellular_component
GO:0043005 neuron projection cellular_component
GO:0043025 neuronal cell body cellular_component
GO:0005815 microtubule organizing center cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005874 microtubule cellular_component
GO:0005875 microtubule associated complex cellular_component
GO:0005881 cytoplasmic microtubule cellular_component
GO:0005635 nuclear envelope cellular_component
GO:0005737 cytoplasm cellular_component
GO:0070840 dynein complex binding molecular_function
GO:0051010 microtubule plus-end binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040116-2 Predicted to enable dynein complex binding activity; microtubule plus-end binding activity; and protein heterodimerization activity. Acts upstream of or within brain morphogenesis. Located in cytoplasm. Is expressed in several structures, including gill; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in lissencephaly and lissencephaly 1. Orthologous to human PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1).

Ensembl:

ensembl_id ENSDARG00000032013

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00018171 False 2252 mRNA 0.48 11 25273185 25319663
TCONS_00018172 False 1671 mRNA 0.48 10 25273470 25304710
TCONS_00018173 True 746 processed_transcript 0.50 4 25278845 25284045

Neighbor

gene id symbol gene type direction distance location
XLOC_009244 mettl16 coding downstream 4157 25214171 ~ 25269028 (-)
XLOC_009243 mnta coding downstream 63877 25172671 ~ 25209308 (-)
XLOC_009242 vps53 coding downstream 119782 25100726 ~ 25153403 (-)
XLOC_009241 rflnb coding downstream 173506 25093291 ~ 25099679 (-)
XLOC_009240 exo5 coding downstream 179159 25084821 ~ 25094026 (-)
XLOC_009246 cluha coding upstream 1909 25321572 ~ 25367309 (-)
XLOC_009247 si:dkey-54n8.4 coding upstream 56260 25375923 ~ 25392589 (-)
XLOC_009248 tlcd2 coding upstream 78464 25398127 ~ 25435085 (-)
XLOC_009249 hif1al coding upstream 182201 25501864 ~ 25527581 (-)
XLOC_009250 mmp20a coding upstream 226313 25545976 ~ 25556227 (-)
XLOC_009236 NA non-coding downstream 299073 24968092 ~ 24974112 (-)
XLOC_009234 NA non-coding downstream 346092 24901551 ~ 24927093 (-)
XLOC_009230 NA non-coding downstream 654280 24592325 ~ 24618905 (-)
XLOC_009228 NA non-coding downstream 710124 24561821 ~ 24563061 (-)
XLOC_009227 CU313324.1 non-coding downstream 1114118 24158953 ~ 24159067 (-)
XLOC_009254 NA non-coding upstream 379149 25698812 ~ 25876120 (-)
XLOC_009256 CR848822.3 non-coding upstream 675317 25994980 ~ 25995095 (-)
XLOC_009257 CR848822.2 non-coding upstream 755700 26075363 ~ 26075480 (-)
XLOC_009258 NA non-coding upstream 797531 26117194 ~ 26183974 (-)
XLOC_009259 CU179658.2 non-coding upstream 954977 26274640 ~ 26274757 (-)

Expression


Co-expression Network